HS301 – Fundamentals Of Biostatistics Summer 2019

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HS301 – Fundamentals of BiostatisticsSummer 2019Instructor:Office:Phone:E-mail:A.Daniel J. McCarty, PhDD143 Science Building(715) 346-2508 (Office)dmccarty@uwsp.eduCourse descriptionFundamentals of Biostatistics (3 credits)This is an introductory course in statistical methods used in applied research for thebiological sciences. The course will emphasize the principles of statistical reasoning,underlying assumptions, hypothesis testing, and careful interpretation of results. Sometopics covered: descriptive statistics, graphical displays of data, probability, confidenceintervals and tests for means, differences of means, sample size and power, differences ofproportions, chi-square tests for categorical variables, regression, multiple regression, andnon-parametric statistics.Prerequisite: Math 95, HS105B.FormatOnline courseC.TextbookBasic Biostatistics by B. Bert Gerstman (Second edition)D.General goals and objectivesE.Grading system93 – 10090 – 9287 – 8983 – 8680 – 82Students will develop a new set of reasoning skills that will provide a foundation fordesigning, analyzing and interpreting research in the biological sciences. This knowledgeand skills are essential in today’s healthcare environment which emphasizes evidencedbased healthcare and health outcome evaluation.At the conclusion of this course students will able to: Appreciate the vital role of biostatistics in healthcare research and in promotingevidenced-based healthcare and health outcome evaluation. Articulate the underlying concepts and assumptions for major study designs,hypothesis testing and common analytical methods. Demonstrate quantitative skills such as the ability to organize raw data, graphicallyexplore the data distributions, conduct appropriate statistical analyses and interpretand apply results for problem solving.AAB BB-77 – 7973 – 7670 – 7267 – 6960 – 66Below 60C CCD DF1

“A” reflects exceptional work (going beyond the basics, integrating material well,displaying professionalism in individual and group work, application anddemonstration of knowledge and skills, showing initiative, using creativity,writing is reflective of multiple drafts).“B” reflects good work (valuable teamwork skills, active in class, ability to graspbasic concepts and apply to new situations, some participation in class, completesall assignments with a degree of proficiency but may not demonstrate initiative,creativity or reflection consistently, writing contains errors or lacks concisenessand completeness).“C” reflects average work (assignments are completed at the minimum, basicconcepts are grasped but cannot be applied, some difficulty in group work,spelling and grammar mistakes are common, writing is conversational in tonewith little attention paid to detail, word choices, organization (rough draft quality),little participation in class.Student responsibilities for successful coursework:Attendance: Students must attend all classes and are responsible for allinformation presented in class. Notify the instructor in person, by telephone oremail if an absence is anticipated. Class begins promptly at the scheduled times.Reading Assignments: Additional readings may be posted in D2L. Students willbe more successful in the class if the text and other handouts are read before theclass period during which a given topic will be covered. The course is focused ondiscussion and analysis of topics. Readings will prepare you for participation inclass.If you have any concern about meeting the requirements of this course, please seeme.G.Derivation of course gradeTwo exams (20% each - multiple choice and short answer)Lesson QuizzesActivities (D2L drop box)Final exam (comprehensive)H.Other class information40%15%15%30%Cell phone policy - No text messaging.Email – please note that you are responsible for anything I send you via email.2

I.Communicating with your instructor via emailI check my email frequently during the day. However, I receive a lot of email andI sometimes delete emails which do not have the subject specified. If you have notreceived a response to your email within 24 hours, please resend your email. I donot check email routinely on some weekends.J.Students with special needsStudents with special needs should contact the instructor as early in the semesteras possible to make any necessary class/test accommodations.The contents of this syllabus are as complete and accurate as possible. Theinstructor reserves the right to make any changes necessary to the syllabus andcourse material. The instructor will make every effort to inform the students ofchanges as they occur. It is the responsibility of the student to know what changeshave been made in order to successfully complete the requirements of the course.Any in-class announcement, verbal or written, is considered official addendum tothis syllabus.3

Week#1May 28th Background Reading & LessonsLesson 1a – Introduction to Statistics and (healthcareinformatics)Lesson 1b - Intro to Chance and ProbabilityActivities Deming videos Hans Rosling – The Joy ofStats video (1 hour) Lesson 1a Quiz Lesson 1b Quiz#2June 3rd Read Chapter 1 TextLesson 2 – MeasurementRead Chapter 2 TextLesson 3 – Major Study Designs Lesson 2 Quiz Lesson 3 Quiz#3June 10th Lesson 4 – SamplingChalk talk - SamplingRead Chapter 3 TextLesson 5 – Frequency Distributions Lesson 4 QuizLesson 5 Quiz#4June 17th Read Chapter 4 TextLesson 6 – Summary StatisticsRead Chapter 5 TextChalk talk – Variance partLesson 7 – Probability Concepts Lesson 6 QuizMinitab activity 1 –Frequency and DescriptiveStatisticsLesson 7 Quiz Read Chapter 6 TextLesson 8 – Binomial Probability DistributionsRead Chapter 7 TextLesson 9- Normal Probability DistributionsRead Chapter 8 TextLesson 10 – Introduction to Statistical InferenceChalk talk – Central Limit TheoremRead Chapter 9 TextLesson 11- The Basics of Hypothesis TestingChalk talk – Hypothesis TestingChalk talk – Sample Size and PowerRead Chapter 10 TextLesson 12- Confidence IntervalsReview for Exam 1Exam 1Read Chapter 11 textLesson 13- Inferences about a Mean #5June 24th#6July 1st#7July 8th#8July 15th#9July 22nd Lesson 8 QuizMinitab activity 1 answersdue on D2LLesson 9 QuizLesson 10 QuizLesson 11 QuizLesson 12 Quiz Exam 1Lesson 13 quizRead Chapter 12 TextLesson 14- Comparing Independent MeansChalk talk – T-TestsRead Chapter 13 TextLesson 15 - Comparing Several MeansChalk talk – ANOVA Lesson 14 QuizMinitab activity 2– t-testsLesson 15 QuizMinitab activity 3– ANOVARead Chapter 14 TextLesson 16 - Correlation and RegressionChalk talk – CorrelationChalk talk – RegressionRead Chapter 15 Minitab activity 2 answersdue on D2LMinitab activity 3 answersdue on D2LLesson 16 Quiz 4

Lesson 17 –Multiple Linear Regression #10July 29th#11Aug 5th#12Aug 12th Review for exam 2Exam 2 – Intro concepts plus Chapters 10-15Read Chapter 16Lesson 18 - Inference about a ProportionRead Chapter 18 and Chapter 19Lesson 19 – Chi-sq testChalk talk – Chi-sqReview for the Final ExamFinal exam due by Aug 16th by 11:59pm Lesson 17 QuizMinitab activity 4 Correlation and RegressionMinitab activity 4 answersdue on D2LLesson 18 QuizMinitab activity 5– Chi-sqanalysisLesson 19 QuizMinitab activity 5 answersdue on D2L5

Fundamentals of Biostatistics (3 credits) This is an introductory course in statistical methods used in applied research for the biological sciences. The course will emphasize the principles of statistical reasoning, underlying assumptions, hypoth

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