POCKET GUIDE

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POCKET GUIDEfor theINTERN & MEDICAL STUDENT

Table of contentsWelcome3Description of urology clinical service4Sub-intern goals and responsibilities4-7Intern goals and responsibilities8-9Overview of residency10Research at MGH Department of Urology11-12Basic concepts in urologyUrologic emergenciesGenitourinary trauma13-17Priapism17-20Fournier’s gangrene21-22General UrologyUrinary retention23-27Acute Renal Colic27-29Erectile dysfunction29-31Benign prostatic hyperplasia (BPH)31-33Evaluation of scrotal masses33-34Urinary tract infection35-38Urologic OncologyRenal Cell Carcinoma & Renal Cysts39-42Upper Tract Urothelial Carcinoma42-44Bladder Cancer45-47Prostate Cancer48-52ProceduresFoley catheter placement/Bladder irrigation53-57Bedside cystoscopy57-59Priapism – Corporal Irrigation59-60Updated 6/20152

WelcomeDear sub-intern/intern,We are proud to welcome you to the MGH department of urology. This is a very excitingtime in your career and finding a residency that fits you is of utmost importance. The goal ofour residency is to train you to be the best urologic surgeon you can be, and expose you to allaspects of urology. In addition, we hope to provide opportunities to help develop your interestsand take full advantage of the opportunities for collaboration that come along with training inthe city of Boston.In this guide you will find an introduction to our department and to provide you withbasic information that you might find useful during your initial arrival at MGH. More specific toour interns, we provide you a list of the faculty’s research interests and guidelines for choosinga mentor and project as you progress through your intern year.Michael L. Blute, MDChairmanAria F. Olumi, MDResidency Program DirectorUpdated 6/20153

Description of urology clinical serviceThe current clinical service is divided into three separate teams (Leadbetter, O’neil, andKerr). Average daily patient census is 6-8 patients per service. Each service has a junior resident,chief resident, and occasionally an intermediate resident. We have a wonderful PA, Diane Levis,who usually covers the O’neil and Kerr services while junior residents are in the operatingroom. The intern usually spends time on Leadbetter during which he/she will carry theemergency department consult pager and cover the patients on that service. Sub-interns willrotate through two of the teams (2 weeks on each team) at the discretion of the chiefresidents.Sub-intern rotation detailsAccommodationsPlease make plans for accommodations early since it can be challenging to find a place close toMGH. If you have any questions or have difficulty obtaining a place to stay please contact KimWilliams (kwilliams40@partners.org) and she well put you in touch with a resident who may beable to assist you. Consider proximity to the public transportation when choosing a place tostay.Useful tatingroom.com/ - sublet website for medical students, by medical students.Please be advised that these listings are provided simply as a convenience to students and thatwe do not officially endorse these establishments. Arrangements are made independentlybetween the establishment and the student.Public transportationBoston is a city with excellent public transportation. Please check the MBTA website(http://www.mbta.com/) for up to date information. Please note the earliest times that the Topens to properly plan your arrival for rounds during your rotation.Identification cardsThe ID office is located on the second floor of the Wang building. When you exit theelevators make a right and follow the signs to the MGH security office. There you will be able toget your picture ID.Updated 6/20154

Important locationsUrology resident call room – located in the Gray/Bigelow building on the 11th floor. This iswhere you will go to print your team lists and where operating room schedules will be postedon the board.Urology offices/library – Gray/Bigelow 1102. To access the urology library turn right afterentering the urology offices and head down the hall towards the room at the end.Emergency department – located on the first floor close to the Fruit street entrance to thehospital. As a sub-intern you are encouraged to follow the intern/residents to see consults inthe emergency department to get an idea of the breadth of consults that we have theopportunity to see at MGH as a result of being a large tertiary and level 1-trauma center.Cafeteria – located in the basement. There is also a coffee shop outside of the Gray/Bigelowelevators on the first floor and a small cafeteria on the basement floor of the Wang building.Computers – if there are no available computers in the urology call room you can use thecomputer in the urology library or you can use the resident lounge on the first floor of theWang building.Computer access/Online resourcesAfter obtaining computer access, please double check that you have access to CAS,Mosaic, and Apprentice. You will use these programs to access patient clinical information,operating room schedules, and to help print patient lists for rounds, respectively. If you do nothave access to these programs, please email Cindy Murphy (CMURPHY3@mgh.harvard.edu).Meeting with Chief residentEach sub-intern should meet with one of the three chief residents during the first fewdays of the rotation to discuss goals and responsibilities for the month.Team-workSub-interns are expected to work together as a team with their co-residents andmedical students. We expect that you will try to incorporate yourself into the team and reallytry to experience what it may be like to be an MGH resident. Your focus should be on trying tofollow your patients throughout the rotation (e.g. volunteer to write the post-op check on thepatient who you were in the OR with). At times there may be up to four other medical studentson service. Make sure that you are working together to assign each other cases in a way thatwill allow you to obtain a grasp of the different procedures performed at MGH, but also giveyou an opportunity to get to know the faculty.Pre-rounding/roundingTouch base with the junior resident on your team to find out exact details about how topre-round and other tasks that may be helpful in the morning. Rounds usually start at 6 AM, butUpdated 6/20155

may be earlier if there are conferences scheduled that morning or the team has a particularlylarge census (important to take into account when choosing your accommodations). Try to preround (obtain vitals) on the patients in your team if time allows. There will be times that the listwill be very large. In general, try to at least pre-round on the patients whom you have seen inthe OR and examine them before rounds. It will be up to your team chief, but you should try tocome up with an assessment and plan for your patient to be presented during rounds. Helpfollow-up on tasks during the day that may be helpful to other team members.Operating roomThe first day of the rotation make sure to take the scrub class so that you are able toscrub into cases. Once you are done with your scrub class please report to the urology officewhere Cindy Murphy will give you the information about who to report to next.The operating room schedule will be posted in the call room several days in advance.Please make sure to discuss which cases you will be scrubbing in on with your fellow medicalstudents a couple of days prior to the operation to allow time for preparation. In general, try tospend the day with one attending rather than trying to bounce around different rooms. This willgive you an opportunity to get to know the faculty in the department.You should have access to the patient’s medical record including clinic visits, imaging,and pathology. Make sure you come prepared to discuss the patient’s presentation, physicalexam findings, and indication for the procedure. In addition, be ready to discuss relevantanatomy for the procedure. You have access to Campbell’s urology through the MGH Treadwelllibrary (http://www2.massgeneral.org/library/ - ebooks - search for Campbell’s urology - login with partners username and password). Alternatively, in CAS you have a tab that is called“handbook” which contains links to pubmed, ebooks, and UptoDate for your review.ClinicDuring your rotation try to spend at least one afternoon per week in clinic to get a sensefor what office urology is like (schedule included in the appendix). This will be another way foryou to get to know the faculty in the department.PresentationMedical students who are applying to urology residency programs are required to give a10-minute presentation (8 minutes plus 2 minutes for questions) on a topic of their choice.Residents should try to identify a topic early on in the rotation and ask the chief residents forguidance on the specific topic. This should be a focused presentation with a thorough literaturereview. Students should be able to show mastery in the specific area and try to avoidpresenting summaries of chapters in Campbell’s. Furthermore, try to stay away from choosingtopics that are currently controversial in the field and/or do not have a clear consensus.Updated 6/20156

Letters of recommendationStudents should try to schedule a meeting with Dr. Blute (please email Cindy Murphy atcmurphy3@mgh.harvard.edu) towards the end of their rotation to discuss the departmentalletter of recommendation. Letters will be a compilation of comments received from residents,faculty, and assessment of your presentation. Please bring a copy of an up to date CV to yourmeeting with Dr. Blute.Updated 6/20157

Intern goals and responsibilitiesScheduleYou will have a total of 3 months of urology during your intern year. Your schedule willusually be Monday through Saturday. During your general surgery rotation you will rotatethrough surgical oncology, pediatric surgery, SICU, trauma surgery, and general surgery.ObjectivesThe objectives of the urology intern rotation:1.2.3.4.Become familiar with the management of post-operative urologic patientsUnderstand the management of common emergent urological consultsBecome facile in the placement of difficulty Foley catheters and bladder irrigationLearn the basics of endoscopy in the operating roomTeam-workThe intern will usually start on the Leadbetter service as the responding clinician andhold the emergency department consult pager (see details below). The urology intern jobcomes with great responsibility as you will be the first one assessing patients in the emergencydepartment and in charge of triaging these patients. If our PA is off, the intern will often assistin covering the list of the post-call resident.KnowledgeDr. Olumi will be providing you (the Urology categorical interns) with a copy of Smith’sUrology that you should read in completion during your intern year. In preparation for the inservice we will have a mock 25-question exam after intern year and 50-question exam afteryour first year of urology.ConsultsThe intern usually holds the consult pager that is usually used to call intra-operative,emergency department, and occasionally floor consults. Intra-operative – you will at times be called directly from the operating room for anintra-operative consult. This will range from a difficulty Foley placement toassistance with a potential bladder and/or ureteral injury. If it is the latter, try to getas much information about their primary concern, patient name/MRN, andimmediately contact the proper attending with the details of the consult. For theformer, ask about what catheters have been tried. Prior to going to the operatingroom make sure to take a thorough look through the patient’s history, labs, andprior imaging to look for a history of BPH, urethral stricture disease, and/or priorurologic surgery.Updated 6/20158

Emergency department – the most common emergent consults include symptomaticnephrolithiasis (pain /- infection) – of which patients may present with urosepsis,urinary retention, epididymoorchitis, Fournier’s gangrene, priapism, and hematuria.Please make sure to read about these conditions prior to the start of your rotation.Floor/Inpatient – the consult resident will usually take care of the floor consults, butyou will occasionally be called to assist with difficult Foley placements and to assistwith bladder irrigations in patients with clot retention. During the weekends you willbe in charge of taking all consults with the assistance of the on-call junior resident.Operating roomDuring your urology rotation you should become familiar with the instruments used forcystoscopy and basics of common endourologic procedures.MentorshipDr. Olumi will meet with you within the first couple of months of your intern year toassign you a mentor in the department of urology. If you are choosing to take time after internyear to do research it will be important to start thinking about a potential area of interest andprojects.Updated 6/20159

Overview of residencyThe MGH residency provides trainees a strong clinical exposure to general urology,urologic oncology, stone disease, infertility, voiding dysfunction, female urology, and pediatricurology. Residents have the opportunity to rotate through Children’s Hospital Boston duringtheir senior years. Laparoscopic and robotic skills are solidified during the later years of training.One unique aspect of this residency is the ability to become a junior attending at theend of residency. All urology interns have the same general surgery and urology rotations.During the PGY-2/URO-1 year, residents are staggered into urology every four months –resident 1 enters his/her PGY-2/URO-1 year immediately, resident 2 four months later, andresident 3 four months after resident 2 enters. This provides those residents who enter urologyat a later time the opportunity to do more general surgery rotations or use the time to performresearch. At the end of residency trainees remain on staff as the “Cabot attending” duringwhich he/she will have attending privileges at MGH and be in charge of their own clinic,overseeing the resident clinic, and take call for trauma at a level 1 trauma center. This uniqueexperience allows residents to work as attendings under the continued guidance of the MGHfaculty.Conference curriculumTuesday morning resident conferencesResidents take turns leading weekly discussions of a particular topic in urology. Eachsession is led by a faculty member with particular expertise in the topic presented.Thursday morning indications and grand roundsEvery Thursday morning at 7 AM residents meet to discuss cases scheduled through theurology resident clinic and staffed with the Cabot attending. Grand rounds usually runs from7:30 to 9:30 AM where we have lectures from faculty within the department of urology, otherMGH departments, resident case presentations, or GU oncology conferences.Oncology fellowshipThere are two fellows per year in the combined Brigham and Women’s Hospital/MGHurologic oncology fellowship. The fellows rotate through both hospitals and are a tremendousasset to resident education and training. Fellows are also keen to involve residents in ongoingresearch.Updated 6/201510

Research at MGH Department of UrologyKidney Cancera. A comparison of nephron sparing techniques: percutaneous radiofrequency ablation(RFA) vs. open and laparoscopic partial nephrectomy (Feldman)b. Renal Biopsy for suspicious renal masses: The MGH cohort of 1000 patients (Feldman)c. Molecular pathogenesis of angiomyolipoma and other TSC related neoplasms (Wu –funded by NIH/Program Project)Bladder Cancera. Multi-institutional bladder cancer quality care initiative for non-metastatic muscleinvasive transitional cell carcinoma of the bladder (Feldman)b. RTOG 0926: Phase II – Management of aggressive forms of stage T1 bladder cancer withtrimodality therapy (TURBT, chemotherapy, and radiation) (Dahl)c. RTOG 0524: Paclitaxel and radiation therapy with or without Trastuzumab in treatingpatients who have undergone surgery for bladder cancer (Dahl)d. Genetic signatures in T1 G3 bladder cancer (McDougal)Prostate Cancera. 5-alpha reductase 2 expression in adult prostate tissue (Olumi – funded by NIH/R01)b. Biomarkers for active surveillance in prostate cancer (Feldman – funded by DOD &Prostate Cancer Foundation)c. Circulating tumor cell (CTC) analysis in prostate cancer (Dahl)d. Molecular mechanisms of resistance to pro-apoptotic therapies (Olumi – funded by NewYork Academy of Medicine)e. Metabolic state of prostate cancer cells determines sensitivity to Metformin in prostatecancer cells (Olumi)f. Genetic signatures in prostate cancer (McDougal & Wu)g. Template biopsy in patients who are highly suspicious for having prostate cancer buthave had negative biopsies (McDougal)h. Metabolomics of prostate cancer in prostate biopsy specimens (McDougal & Wu –funded by NIH)Updated 6/201511

Penile Cancera. Penile conserving surgery for penile cancer (McDougal)Infertilitya. Sperm vitrification (Tanrikut)b. Clinical outcomes related to testosterone replacement therapy (Tanrikut)c. Dietary impacts on semen parameters (Tanrikut)Nephrolithiasisa. Analysis of 24-hour urines and risk factors for recurrent nephrolithiasis (Eisner)b. Use of paravertebral nerve block in patients undergoing percutaneous nephrolithototmy(Eisner)c. Predictive factors and stone characteristics for patients evaluated in the emergencydepartment with flank pain (Eisner)d. Novel MRI applications for the detection of renal stones (Eisner)Tissue Biobank (Wu & McDougal – Funded by MGH Bertucci Research Fund)a.b.c.d.e.Prostate: 3547Kidney: 1091Bladder: 244Testis: 140Adrenal: 221Updated 6/201512

UROLOGIC EMERGENCIESGenitourinary Trauma Tim Brown, MD,PhDIndications for genitourinary (GU) evaluation in a trauma patient:o Traumatic hematuriao Gross hematuriao Penetrating traumao Pediatric patient and any degree of hematuriao Blunt trauma with microscopic hematuria and shockIndications for evaluation of GU trauma in the absence of hematuria:o Mechanism of injury: rapid deceleration or flank injuryo Clinical findings (mechanism of injury): flank ecchymosis, flank pain, posteriorrib fractures, transverse process fractures near kidney, pelvic fracture, etcRadiologic studies:o Abodomen/pelvis CT with delays: suspected renal/ureteral injuryo CT-cystogram: suspected bladder injuryo RUG (retrograde urethrogram): suspected urethral injuryo Scrotal ultrasound: testicular injuryRenal trauma Factso Most common GU organ injured by traumao Blunt trauma accounts for 90% of renal injurieso Children are more susceptible to renal trauma due to less perirenal fat,underdeveloped rib cage and less muscleEvaluationo Imaging study of choice: 2-phase contrast renal CT Vascular/cortical phase 30 seconds after IV contrast Delayed phase 10 minutes later to assess for perirenal or ureteralextravasationo IVP and Ultrasound are low yield and less reliable Single shot IVP can be used in unstable patient in the OR to confirmpresence of a contralateral kidneyClassificationo Grade 1: contusion or subcapsular hematomao Grade 2: cortical laceration 1cm, no extravasationo Grade 3: cortical laceration 1cm, no extravasationo Grade 4: laceration 1 cm deep into collecting system OR vascular injury(thrombosed renal artery or segmental vein injury)o Grade 5: shattered kidney OR renal pedicle avulsionManagementUpdated 6/201513

o Initial observation is appropriate for patient with renal parenchymal injury andurinary extravasationo The only absolute indication for renal exploration is hemodynamic instabilityfrom renal injury (should avoid unnecessary exploration due to risk of releasingperirenal tamponade)o Urinary drainage via ureteral stent should be performed in the presence of anenlarging urinoma, fever, increasing pain, ileus, fistula or infection. May need toaugment with percutaneous drain, percutane

POCKET GUIDE . for the . INTERN & MEDICAL STUDENT . Table of contents Welcome 3 . Description of urology clinical service 4 . . We are proud to welcome you to the MGH department of urology. This is a very ex

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