Emmanouil S. Brilakis, MD, PhD
Emmanouil S. Brilakis, MD, PhDCONTACT INFORMATIONWORKDallas VA Medical Center (111A)4500 South Lancaster Road, Dallas, TX 75216cell: 214-284-2667office: 214-857-1547pager: (972) 614-0465 (metrocall.com)fax: hoo.comemmanouil.brilakis@utsouthwestern.eduWORK EXPERIENCE2004 Director, Cardiac Catheterization Laboratory, VA North Texas Health CareSystem, Dallas, TXPRESENT ACADEMIC RANK AND POSITION2004 Assistant Professor in Medicine, University of Texas Southwestern, Dallas, Texas2004Assistant Professor in Medicine, Mayo Medical School, Rochester, Minnesota2001-2004Instructor in Medicine, Mayo Medical School, Rochester, MinnesotaEDUCATION AND TRAINING2007Training in Cardiac Computed Tomography, Lenox Hill Heart and VascularInstitute, New York, New York2005PhD in Clinical Research, School of Medicine, National University of Athens,Greece2003-2004Fellow in Interventional Cardiology, Mayo Clinic, Rochester, Minnesota2/2004Masters in Clinical Research, Mayo Graduate School, Rochester, Minnesota2000-2003Fellow in Cardiology, Mayo Clinic, Rochester, Minnesota1997-2000Resident in Internal Medicine, Mayo Clinic, Rochester, Minnesota1995-97Resident in Internal Medicine, General Military Hospital, Athens and Xanthi,Greece1
1989-95Doctor of Medicine, High Honors, School of Medicine, National University ofAthens, GreeceRESEARCH FUNDING2007-2008American Heart Association – “Get With The Guidelines” Young InvestigatorDatabase Research Grant - amount to be determinedClinical presentation, use of coronary revascularization, use of atherosclerosissecondary prevention performance measures, and in-hospital mortality in acutecoronary syndrome patients: comparison between patients with and without priorhistory of peripheral vascular disease2007-2008UT Arlington – UT Southwestern Joint Venture Grant for CollaborativeResearchCo-PI 100,000Development of a novel biodegradable stent in collaboration with Drs Jian Yang andPanos Shiakolas (Department of Bioengineering and Mechanical Engineering,University of Texas Arlington)2006Clark R. Gregg fund, Harris Methodist Foundation Grant.PI 80,000Multicenter enrollment support for the SOS (Stenting Of Saphenous vein grafts)randomized-controlled trial of a paclitaxel-eluting stent vs. a bare metal stent insaphenous vein graft lesions6/20056/2007Veteran Affairs VISN-17 Startup Award.PI 100,000Research Coordinator support for the SOS (Stenting Of Saphenous vein grafts)randomized-controlled trial of a paclitaxel-eluting stent vs. a bare metal stent insaphenous vein graft lesions2004Dallas VA Research Corporation Startup Grant.PI 20,000The SOS (Stenting Of Saphenous vein grafts) randomized-controlled trial of apaclitaxel-eluting stent vs. a bare metal stent in saphenous vein graft MinnesotaPUBLICATIONS1. Brilakis ES, Banerjee S. Successful Retrograde Treatment of a Mid Left Anterior Descending ArteryChronic Total Occlusion Using a Novel “Guide Parallel to Wire” Technique. Catheter Cardiovasc Interv;in press2
2. Dimas B, Lindsey JB, Banerjee S, Brilakis ES. ST-segment Elevation Acute Myocardial infarction DueTo Severe Hypotension and Proximal Left Subclavian Artery Stenosis in a Prior Coronary ArteryBypass Graft Patient. Cardiovasc Revasc Med; in press3. Boatman D, Saeed B, Varghese I, Peters CT, Daye J, Peters Haider A, Roesle M, Banerjee S, BrilakisES. Prior coronary artery bypass graft surgery patients undergoing diagnostic coronary angiographyhave multiple uncontrolled coronary artery disease risk factors and high risk for cardiovascular events.Heart Vessels; in press4. Dustin M. Boatman*, Bilal Saeed*, Indu Varghese*, Calvin T. Peters*, Jad Daye*, Aman Haider*,Michele Roesle*, Subhash Banerjee*, Emmanouil S. Brilakis*5. Brilakis ES, Khera A, Saeed, B, , Banerjee S , McGuire DK, Murphy SA, de Lemos JA. Association ofLipoprotein-Associated Phospholipase A2 Mass and Activity with Coronary and AorticAtherosclerosis: Findings From the Dallas Heart Study. Clin Chemistry; in press6. Brilakis ES, de Lemos JA, Cannon CP, Wiviott SD, Murphy SA, Morrow DA, Sabatine MS, BanerjeeS, Blazing MA, Califf RM, Braunwald E. Outcomes of Patients With Acute Coronary Syndrome andPrior Coronary Artery Bypass Grafting. Results (From the Pravastatin or Atorvastatin Evaluation andInfection Therapy [PROVE-IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials). Am J Cardiol; inpress7. Brilakis ES, Banerjee S. The “Proxis-Tornus” technique for a difficult to cross calcified saphenous veingraft lesion. J Invasive Cardiol; in press8. Prasad A, Prasad A, Varghese I, Roesle M, Banerjee S, Brilakis ES. Prevalence and treatment ofproximal left subclavian artery stenosis in patients referred for coronary artery bypass surgery. Int JCardiol; in press9. Banerjee S, Varthese C, Samuel J, Weideman RA, Little BB, Kelly KC, Rao SV, Reily RF, Brilakis ES.Prolonged Clopidogrel Use Following Percutaneous Coronary Intervention is Associated with LowerMortality. Am J Cardiol; in press10. Warner JJ, Weideman RA, Kelly KC, Brilakis ES, Banerjee S, Cunningham F, Harford WV, Kazi S,Little BB, Cryer B. The Risk of Acute Myocardial Infarction With Etodolac is Not IncreasedCompared to Naproxen: A Historical Cohort Analysis of a Generic COX-2 Selective Inhibitor. Journalof Cardiovascular Pharmacology and Therapeutics 2008:1074248408323136.11. Brilakis ES, Brilakis HS. Pursuing Postgraduate Training in Internal Medicine and Cardiology in theUSA: An Introduction for Greek Physicians. Hellenic J Cardiol 2008; 49: 222-22612. Daye J, Boatman D, Peters C, Varghese I, Haider A, Roesle M, Jessen ME, DiMaio JM, Banerjee S,Brilakis ES. Perioperative Risk of Patients Undergoing Noncardiac Surgery After Coronary ArteryBypass Surgery. J Investig Med 2008;56:878-88113. Varghese I, Ummer A, Roesle M, Banerjee S, Brilakis ES. Recurrent late drug-eluting stent thrombosisupon discontinuation of antiplatelet therapy. Cardiovasc Revasc Med 2008;9:179-1813
14. Brilakis ES, Khera A, McGuire DK, See R, Banerjee S, Murphy SA, de Lemos JA. Influence of Raceand Sex on Lipoprotein-Associated Phospholipase A2 Levels: Observations from the Dallas HeartStudy. Atherosclerosis 2008;199:110-11515. Brilakis ES, Saeed, B, Banerjee S. Use of Drug-Eluting Stents in Saphenous Vein AortocoronaryBypass Graft Lesions: a Critical Appraisal. J Interv Cardiol 2008;21:151-15716. Varghese I, Boatman DM, Peters CT, Daye J, Haider A, Roesle M, Banerjee S, Brilakis ES. Impact onContrast, Fluoroscopy, and Catheter Utilization From Knowing the Coronary Artery Bypass GraftAnatomy Before Diagnostic Coronary Angiography. Am J Cardiol 2008; 101:1729-173217. Prasad A, Cipher DJ, Prasad A, Mohandas A, Roesle M, Brilakis ES, Banerjee S. Reproducibility ofIntravascular Ultrasound Virtual Histology Analysis. Cardiovasc Revasc Med 2008;9:71-7718. Banerjee S, Compton PA, Hooker RS, Cipher DJ, Reimold A, Brilakis ES, Banerjee P, KaziS.Cardiovascular Outcomes in Male Veterans with Rheumatoid Arthritis (COVARA). Am J Cardiol;2008;101:1201-120519. Haider A, Banerjee S, Brilakis ES. Acute Pulmonary Edema due to Pacemaker-Induced MitralRegurgitation. J Invasive Cardiol; 2008;20:E8420. Lindsey JB, Brilakis ES, Banerjee S. Extrinsic Compression of the Left Main Coronary Artery Treatedwith Percutaneous Coronary Intervention. A Case Report and Review of the Literature. CardiovascRevasc Med 2008;9:47-5121. Prasad A, Compton PA, Prasad A, Roesle M, Makke L, Rogers S, Banerjee S, Brilakis ES. Incidenceand treatment of arterial access dissections occurring during cardiac catheterization. J Interv Cardiol2008;21:61-6622. Lindsey JB, Banerjee S, Brilakis ES. Two “buddies” may be better than one: use of two buddy wires toexpand an under-expanded left main coronary stent. J Invasive Cardiol 2007;19:E355-35823. Brilakis ES, Banerjee S, Berger PB. Perioperative management of coronary stents. J Am Coll Cardiol2007;49:2145-5024. Brilakis ES, Banerjee S, Berger PB. The risk of drug-eluting stent thrombosis with noncardiac surgery.Curr Cardiol Rep 2007;9:406-1125. Iturbe JM, Banerjee S, Brilakis ES. Exertional dyspnea due to spontaneous coronary artery dissectionin a 55-year-man. Heart 2007;93:121226. The Lp-PLA2 Studies Collaboration; Ballantyne C, Cushman M, Psaty B, Furberg C, Khaw KT,Sandhu M, Oldgren J, Rossi GP, Maiolino G, Cesari M, Lenzini L, James SK, Rimm E, Collins R,Anderson J, Koenig W, Brenner H, Rothenbacher D, Berglund G, Persson M, Berger P, Brilakis E,McConnell JP, Koenig W, Sacco R, Elkind M, Talmud P, Rimm E, Cannon CP, Packard C, BarrettConnor E, Hofman A, Kardys I, Witteman JC, Criqui M, Corsetti JP, Rainwater DL, Moss AJ, RobinsS, Bloomfield H, Collins D, Packard C, Wassertheil-Smoller S, Ridker P, Ballantyne C, Cannon CP,Cushman M, Danesh J, Gu D, Hofman A, Nelson JJ, Thompson S, Zalewski A, Zariffa N, Di4
Angelantonio E, Kaptoge S, Thompson A, Thompson S, Walker M, Watson S, Wood A. Collaborativemeta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovasculardiseases. Eur J Cardiovasc Prev Rehabil. 2007;14:3-1127. Wolk R, Berger PB, Lennon RJ, Brilakis ES, Davison DE, Somers VK. Association between plasmaadiponectin levels and unstable coronary syndromes. Eur Heart J 2007;28:292-828. Brilakis ES, Roesle M, Banerjee S. Stent Deformation after Catheter Advancement through a RecentlyDeployed Self-Expanding Stent: Diagnosis, Mechanism and Correction. J Invasive Cardiol 2007:19:4629. Banerjee S, Cho M, Gupta S, Brilakis ES. Aberrant Takeoff of a Right Accessory Renal ArteryIdentified during an Aortoiliac Intervention. Vasc Dis Management 2007;4:4-5.30. Tsimikas S, Brilakis ES, Lennon RJ, Miller ER, Witztum JL, McConnell JP, Kornman KS, Berger PB.Relationship of IgM and IgG autoantibodies to oxidized low density lipoprotein and apolipoproteinB100-immune complexes with angiographically determined coronary artery disease and cardiovascularevents. J Lip Res 2007;48:425-43331. Prasad A, Banerjee S, Brilakis ES. Hemodynamic consequences of massive coronary air embolism.Circulation 2007;115:e51-332. Compton PA, Zankar AA, Adesanya AO, Banerjee S, Brilakis ES. Risk of Non-Cardiac Surgery AfterCoronary Drug-Eluting Stent Implantation. Am J Cardiol 2006 ;98:1212-333. Yang EH, Brilakis ES, Reeder GS, Gersh BJ. Modern management of acute myocardial infarction. CurrProbl Cardiol 2006,31:769-81734. Banerjee S, Brilakis E, Zhang S, Roesle M, Lindsey J, Philips B, Blewett CG, Terada LS.Endothelial progenitor cell mobilization after percutaneous coronary intervention. Atherosclerosis2006,89:70-535. Williams BA, Wright RS, Murphy JG, Brilakis ES, Reeder GS, Jaffe AS. A new simplifiedimmediate prognostic risk score for patients with acute myocardial infarction. Emerg Med J 2006; 23:186 – 19236. Brilakis ES, Best PJM, Elesber AA, Barsness GW, Lennon RJ, Holmes DR Jr, Rihal CS, GarrattKN. PB. Incidence, Retrieval Methods, and Outcomes of Stent Loss During PercutaneousCoronary Intervention: A Large Single Center Experience. Catheter Cardiovasc Interv 2005;66:333-34037. Brilakis ES, Orford JL, Fasseas P, Wilson SH, Melby S, Lennon RJ, Berger PB. Clinical Outcome ofPatients Undergoing Balloon Angioplasty vs. Stent Placement in the Two Months Prior to NonCardiac Surgery. Am J Cardiol 2005;96:512-438. Tsimikas S, Brilakis ES, Miller ER, McConnell JP, Lennon RJ, Kornman KS, Witztum JL, BergerPB.Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med2005;353(1):46-5739. Brilakis ES, Friedman PA, Maounis TN, Rokas SG, Shen WK, Stamatelopoulos SF, Cokkinos DV.Programmed Ventricular Stimulation in Patients with Idiopathic Dilated Cardiomyopathy and5
Syncope Receiving Implantable Cardioverter-Defibrillators: A Case Series and A Systematic Reviewof the Literature. Int J Cardiol 2005;98:395-40140. Brilakis ES, McConnell JP, Lennon RJ, Elesber AA, Meyer JG, Berger PB. Association ofLipoprotein-Associated Phospholipase A2 Levels With Coronary Artery Disease Risk Factors,Angiographic Coronary Artery Disease, and Cardiovascular Events at Follow-Up. Eur Heart J2005;26:137-44 act/ehi010?ijkey 20OQzbr41. Wolk R, Berger P, Lennon RJ, Brilakis ES, Johnson BD, Somers VK. Plasma leptin level andprognosis in patients with established coronary atherosclerosis. J Am Coll Cardiol 2004;44:1819-2442. Brilakis ES, Maniu CV, Wahl MR, Barsness GW. Unstable angina due to stent fracture. J InvasiveCardiol 2004:16:54543. Brilakis ES, Nishimura RA. Dynamic respiratory changes in hypertrophic cardiomyopathy; Heart2004;90:29644. Brilakis ES, Wright RS, Kopecky SL, Mavrogiorgos NC, Reeder, GS, Gersh BJ, Williams BA,Clements IP. Association of the PURSUIT risk score with predischarge ejection fraction,angiographic severity of coronary artery disease, and mortality in a nonselected, community-basedpopulation with non-ST elevation acute myocardial infarction; Am Heart J 2003;146:811-845. Al-Ahmari S, Chandrasekaran K, Brilakas E, Tahlil W, Dearani J, Malouf J, Gilman G, Seward JB,Tajik AJ Isolated partial anomalous pulmonary venous connection: Diagnostic value of suprasternalcolor flow imaging and contrast echocardiography. J Am Soc Echocardiogr 2003;6:884-946. Work R, Berger PB, Lennon RJ, Brilakis ES, Somers VK. Body mass index. A risk factor forunstable angina and myocardial infarction in patients with angiographically confirmed coronaryartery disease. Cicrulation 2003;108:2206-1147. Brilakis ES, Reeder GS, Gersh BJ. Modern management of acute myocardial infarction. Curr ProblCardiol 2003;28:7-12748. Brilakis ES, Nishimura RA. Severe Pulmonary Hypertension in a Patient with HypertrophicCardiomyopathy: Response to Alcohol Septal Ablation; Heart 2003;89:79049. Brilakis ES, Berger PB, Ballman KV, Rozen R. Methylenetetrahydrofolate reductase (MTHFR)C677T and methionine synthase reductase (MTRR) A66G polymorphisms: association with serumhomocysteine and angiographic coronary artery disease in the era of flour products fortified withfolic acid; Atherosclerosis 2003;168:315-2250. Brilakis ES, McConnell JP, Ballman KV, Klee GG, Berger PB. Lack of association between plasmahomocysteine and angiographic coronary artery disease in the era of folic acid fortified cereal grainflour; Atherosclerosis 2002;165:375-38151. Brilakis ES, Mavrogiorgos NC, Kopecky SL, Wright RS, Reeder, GS, Gersh BJ, Williams BA,Clements IP. Usefulness of QRS duration in the absence of bundle branch block as an earlypredictor of survival in non-ST elevation acute myocardial infarction; Am J Cardiol 2002;89:1013-186
52. Fasseas P, Brilakis ES, Leybishkis B, Cohen M, Sokil AB, Wolf N, Dorn RL, Roberts A,VanDecker W. Association of carotid artery intima-media thickness with complex aorticatherosclerosis in patients with recent stroke. Angiology 2002;53:185-953. Hassan I, Brilakis ES, Thompson RL, Que FG. Surgical management of abdominal tuberculosis; JGastrointest Surg. 2002;6:862-7.54. Brilakis ES, Friedman PA, Gersh BJ, Shen WK. Oral amiodarone and atrial fibrillation. Lancet2001;358:147-855. Brilakis ES, Shen WK, Hammill SC, Hodge DO, Rea RF, Lexvold, NY, Friedman PA. Role ofprogrammed ventricular stimulation and implantable cardioverter-defibrillators in patients withidiopathic dilated cardiomyopathy and syncope. PACE 2001;24:1623-3056. Brilakis ES, Wright RS, Kopecky SL, Reeder GS, Williams BA, Miller WA. Bundle-branch blockas a predictor of long-term survival after acute myocardial infarction. Am J Cardiol 2001;88:205-957. Brilakis ES, Manginas AN, Cokkinos DV. Chronic thromboembolic pulmonary hypertension ina patient heterozygous for both factor V Leiden and the G20120A prothrombin mutation. Heart2001;86:14958. Brilakis ES, Olson LJ, Berry GR, Daly RC, Loisance D, Zucker M, Cooper LT. Survivaloutcomes of patients with giant-cell myocarditis bridged by ventricular assist devices; ASAIO J2000;46:569-57259. Brilakis ES, Olson EJ, McGregor CGA, Olson LJ. Sleep apnea in heart transplant recipients:type, symptoms, risk factors, and response to nasal continuous positive airway pressure. J HeartLung Transplant 2000;19:330-660. Brilakis ES, Wolfe ME, Brilakis HS, Friedman PA. Wide QRS tachycardia refractory topharmacologic interventions and cardioversion. Am J Emerg Med 2000;18:453-45661. Brilakis ES, Young WF Jr, Wilson JW, Thompson GB, Munger TM. Reversible catecholamineinduced cardiomyopathy in a heart transplant candidate without persistent or paroxysmalhypertension. J Heart Lung Transplant 1999;18:376-8062. Brilakis ES, Tajik AJ. 82-year-old man with recurrent syncope. Mayo Clin Proc 1999;74:609-12BOOK CHAPTERS1. Brilakis ES, Berger PB. Management of the DES Patient Undergoing Non-Cardiac Surgery.Braunwald Hear Disease, 8th edition 2008.2. Brilakis ES, Banerjee S. Mechanical Complications of Acute Myocardial Infarction. ACC SelfAssessment Program 7th edition 2008.7
3. Brilakis ES, Garrat KN. Device loss during percutaneous coronary intervention: incidence,complications, and retrieval methods. In Ellis S, Holmes DR (editors), In Ellis S, Holmes DR(editors), Strategic Approaches in Coronary Intervention, Lippincott Williams & Wilkins, 20054. Brilakis ES, Rihal CS. The thrombus containing lesion. In Ellis S, Holmes DR (editors), In Ellis S,Holmes DR (editors), Strategic Approaches in Coronary Intervention, Lippincott Williams &Wilkins, 20055. Garrat KN, Brilakis ES, Bacharach SM. Stent retrieval: devices and technique. In Heuser RR,Henry M (editors). Peripheral Vascular Stenting, Martin Dunitz Ltd, 2004EDUCATIONAL WEBSITE1. Editorial consultant for ACP-PIER (American College of Physicians – Physician’s Information andEducation Resource chapter: “Perioperative Cardiac Risk Assessment. 2007-2008EDITORIALS – LETTERS1. Brilakis ES, Berger PB. Should Bare Metal or Drug-Eluting Stents Be Used During PCI of SaphenousVein Graft Lesions: Waiting For Godot? Catheter Cardiovasc Interv; in press2. Brilakis ES, Berger PB. Treatment of coronary bifurcation lesions: might less be more? Eur Heart J2008;29:704-7063. Brilakis ES, Banerjee S. Letter by Brilakis and Banerjee regarding article, "Impact of internal mammaryartery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft".Circulation. 2006;114:e6484. Brilakis ES, Banerjee S. The Use of Deep Guide Catheter Intubation to Treat a Distal AnastomoticLesion in an Ectatic Sequential Saphenous Vein Graft. TCTMD d/main? nfpb true& pageLabel TCTMDContent&hdCon 14112675. Brilakis ES. Risk of surgery after coronary stent placement. Letter to the editor. British Journal ofAnaesthesia. 2006. 66. Brilakis ES, Banerjee S. Continuation of clopidogrel may be safe during bronchoscopy with biopsy.Letter to the editor. Chest 2006. 7. Brilakis ES, Kopecky SL, Wright RS, Reeder GS, Williams BA, Clements IP. Evaluation of theEMMACE model in a US population with non-ST elevation acute myocardial infarction. s/86/2/150PRESENTATIONS8
1. Brilakis ES, de Lemos JA, Cannon CP, Wiviott SD, Murphy SA, Morrow DA, Sabatine MS, BanerjeeS, Blazing MA, Califf RM, Braunwald E. Outcomes of Patients With Acute Coronary Syndromes andPrior Coronary Artery Bypass Grafting. Results From the Pravastatin or Atorvastatin Evaluation andInfection Therapy (PROVE-IT-TIMI 22) and the Aggrastat to Zocor (A to Z) trials. Circulation. 2007;116: II 3142. Brilakis ES, Khera A, McGuire DK, Murphy SA, de Lemos JA. Race and Gender Differences inLipoprotein-Associated Phospholipase A2 Levels: Results From the Dallas Heart Study.American Heart Association Meeting, Chicago, Illinois, November 20063. Compton PA, Zankar AA, Adesanya AO, Banerjee S, Brilakis ES. Risk of Non-Cardiac SurgeryAfter Coronary Drug-Eluting Stent Implantation. ESC Congress Barcelona, Spain, Se
9. Banerjee S, Varthese C, Samuel J, Weideman RA, Little BB, Kelly KC, Rao SV, Reily RF, Brilakis ES. Prolonged Clopidogrel Use Following Percutaneous Coronary Intervention is Associated with Lower Mortality. Am J Cardiol; in press 10. Warner JJ, Weideman RA, Kelly KC, Brilakis ES, Banerjee S, Cunningham F,
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PULSE MAY 2014 4. World renown Cardiology team at VA North Texas includes Francisco Garcia-Morales MD, Jeffery Hastings MD, Jerrold Grodin MD, Mr. Payne, Subhash Banerjee MD, Emmanouil . Brilakis MD, Elvie Ocampo, Shuaib Abdullah, MD. a. Balloon catheter in diseased valve. b. Balloon with valve in place. c. Balloon inflation to secure the .
Lillian Gelberg, MD Neal Halfon, MD David Hayes-Bautista, PhD Ronald Hays, PhD Felicia Hodge, PhD Robert Kaplan, PhD Clifford Ko, MD Gerald F. Kominski, PhD Mark Litwin, MD, PhD Carol Mangione, MD Marvin Marcus, DDS Vicki Mays, PhD Alex Ortega, PhD, MPH John Peabody, MD Thomas H. Rice, PhD Lisa Rubenstein,
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American Revolution Activity Book This Activity Book contains activity pages that accompany the lessons from the Unit 6 Teacher Guide. The activity pages are organized and numbered according to the lesson number and the order in which they are used within the lesson. For example, if there are two activity pages for Lesson 4, the first will be numbered 4.1 and the second 4.2. The Activity Book .
