Department Of Mechanical Engineering McMaster University .
MECHENG 4BF3Biofluid MechanicsDr. Z. MotamedDepartment of Mechanical EngineeringMcMaster UniversityMECHENG 4BF3 (Biofluid Mechanics)Term 2 (January – April 2021)Velocity (m/s)Secondary flowTurbulent Kinetic energy (N/m2)Reynolds shear stress lty/zahra-k-motamedInstructor:Office:Email:Office hours:Lectures:Tutorials:Course website:Dr. Zahra MotamedABB-C 307motamedz@mcmaster.caMondays, 2 to 4 pm; on Microsoft TeamsTuesdays, Wednesdays, and Fridays, 9:30 - 10:20 am, on Microsoft TeamsWednesday, 1:30 to 2:20 pmvia Avenue to Learn (avenue.mcmaster.ca)Note: Due to the COVID-19 pandemic, all McMaster University courses components will be entirelyonline during the winter of 2021. The lectures will be live (synchronous) lectures on Teams.
MECHENG 4BF3Biofluid MechanicsDr. Z. MotamedCourse Description & Objectives“The essence of our life is ultimately not blood but the fluidity of blood. It is remarkable how readilywe miss this point.” Mair ZamirThe circulatory system consists of the heart and a network of vessels that transport the blood. Theheart consists of two pulsatile pumps in series and circulates blood through the vasculature. Thevasculature consists of arteries, arterioles, capillaries, venules and veins. The circulatory system alsoincludes local circulation subsystems such as cerebral, pulmonary and renal circulations.Blood flow is the lifeline to each cell within our body. The main objective of the course is to learnbasics of blood flow mechanics through the circulatory system and its subsystems. The field ofBiofluid mechanics is broad and multidisciplinary covering motions of blood and vessel walls, complexbiomechanics of the heart, a large network of the blood vessels with complicated geometries,persistent pulse-driven changes in flow and pressure and behavior of blood cells.This course examines the physiology and mechanics of circulation, mechanobiology and thebiomechanics of different components of the circulatory system, in-vivo and in-vitro techniques andtheir medical applications. This course covers normal circulatory system, diseases, and medicaldevices.SignificanceThe extracorporeal systems, such as medical devices, should be tested to satisfy governmentregulations and biofluid is often essential in these tests. Thus, in the development of medical devices,biofluid mechanics plays important roles at all stages from design to evaluation of the hemodynamiceffects of medical devices after implantation in the patient body. Moreover, biofluid mechanics playsmajor roles in uncovering causes of pathologies, in enabling prediction of effectiveness ofinterventions, in allowing systematic testing of possible clinical solutions, and in enablingpersonalization of interventions.Course Topics:Major topics to be covered include: Anatomy and pathophysiology of cardiovascular and respiratory system Flow- pressure relationship in circulatory system Pulse wave velocity and wave reflections Analysis of composite cardiac waveforms Dynamics of pulsatile flow Principles underlying blood flow Biorheology Blood flow visualization techniques in research and clinic Mechanical forces on cardiovascular tissue (blood vessels, the heart) Mechanical forces on cardiovascular cells (endothelial cells, platelets, red and white blood cells) Clinical diagnostic metrics
MECHENG 4BF3Biofluid MechanicsDr. Z. MotamedAudienceThis course has been designed for 4th and 5th year undergraduate students in engineering interestedin learning about biofluid mechanic and its applications. The course will be of interest of students inthe following departments and schools:Mechanical Engineering, Chemical Engineering, Computing and Software, Electrical and ComputerEngineering, Engineering Physics, School of Biomedical Engineering and School of ComputationalScience & Engineering.Email PolicyAll emails directed to the instructor should include a subject prefix of “ME [course number][subject]”.Course MaterialsLecture Notes:The lectures notes will be made available on Avenue. The lectures notes do not always repeatmaterials from supplementary references.Textbooks:There is no specific textbook for this course. The instructor will provide reading material includingcourse notes, articles, videos and schematics. Following are some useful references for the course:-Zamir M (2016) Hemo-Dynamics, Springer.-Nichols W, O’Rourke M, Vlachopoulos C (2011) McDonald’s Blood Flow in Arteries, Sixth Edition,CRC Press, Taylor & Francis Group.-Waite L, Fine JM (2017) Applied Biofluid Mechanics, Second Edition, McGraw Hill.-Kleinstreuer C (2006) Biofluid Dynamics: Principles and Applications, CRC Press, Taylor & FrancisGroup.EvaluationThe final grade will be calculated by combining presentations, term project report and the final examas follows. The percentage marks will be converted to a final letter grade using the standardconversion scale shown in the McMaster Graduate Calendar.First presentation (February 9th & 10th & 12th)& Abstract (February 8th)Second presentation (March 16th & 17th &19th)Final project presentation (To be announced)Term project paper*Bonus20% (10 minutes presentation of project definitionand two-page abstract defining the project)25% (15 minutes presentation of project update)25% (30 minutes presentation of project)30% (Deadline for submission: April 23rd)10%
MECHENG 4BF3Biofluid MechanicsDr. Z. Motamed* In this course, class discussion about the subject matter helps better understanding of the material.To encourage learning from peers and interactive and effective learning, 10% bonus mark isconsidered for contributing to class discussions in synchronous sessions.Term Project: All students will be required to work on a research project in a group of 2 to 3students. The final deliverable will be a written research report. Each group will select a topic andwill prepare a report. Potential topics will be presented to the students during the first lecture. Eachgroup will submit two project reports and each group will give two presentations. Although studentswill do a team project, evaluation will be done for each individual student. Every student equallypresents parts of the project and should mention his or her detailed contribution to the group projectin both reports. The teams should be formed and be informed to the instructor by the end of thethird week of the term.Guidelines: Guidelines for the project reports, presentations and rubrics for evaluating them will bepresented to students at the beginning of semester.Attendance: Class attendance is highly recommended.Class Website: All registered students will have access to the class website via Avenue(avenue.mcmaster.ca). Class announcements, course information and course documents arecontained on this website. This website will be continuously updated with related informationthroughout the semester.Learning OutcomesUpon successful completion of the course, it is expected that the students will be able to: Understand the physiology and anatomy of the circulatory system Understand the governing physics of solid and fluid mechanics applied to the circulatory system Know specific circulatory diseases and how they are related to biofluid mechanics Understand fluid mechanics models currently used for circulatory research problems Understand the effect of mechanical forces on various circulatory cells Understand biomechanical issues in selected circulatory medical devices Have the understanding to develop simple models of circulatory function under varying preload,afterload, and contractility Have the understanding to develop simple models of blood flow in devices and circulatorysystem Have the understanding to develop simple models of stress and strain in blood vessels and hearttissue Be familiar with the current state of the art computational modeling tools, experimental in vitro,in vivo and multi-scale methodologies Develop critical thinking regarding the current research challenges in biofluid mechanics Have the understanding to carry out a circulatory-mechanics research projectNotice Regarding Possible Course ModificationThe instructor and university reserve the right to modify elements of the course during the term. Theuniversity may change the dates and deadlines for any or all courses in extreme circumstances. If any
MECHENG 4BF3Biofluid MechanicsDr. Z. Motamedmodifications become necessary, reasonable notice and communication with the students will begiven with explanation and the opportunity to comment on changes. It is the responsibility of thestudent to check their McMaster email and course websites weekly during the term and to note anychangesEquity, Diversity, and InclusionEvery registered student belongs in this course. Diversity of backgrounds and experiences is expectedand welcome. You can expect your Instructor to be respectful of this diversity in all aspects of thecourse, and the same is expected of you. The Department of Mechanical Engineering is committed tocreating an environment in which students of all genders, cultures, ethnicities, races, sexualorientations, abilities, and socioeconomic backgrounds have equal access to education and arewelcomed and treated fairly. If you have any concerns regarding inclusion in our Department, inparticular if you or one of your peers is experiencing harassment or discrimination, you areencouraged to contact the Chair, Associate Undergraduate Chair, Academic Advisor or to contact theEquity and Inclusion Office.Physical and Mental HealthFor a list of McMaster University’s resources, please refer to the Student Wellness Centre. There isalso a list of resources appended to this document.Academic IntegrityYou are expected to exhibit honesty and use ethical behaviour in all aspects of the learning process.Academic credentials you earn are rooted in principles of honesty and academic integrity. It is yourresponsibility to understand what constitutes academic dishonesty. Academic dishonesty is toknowingly act or fail to act in a way that results or could result in unearned academic credit oradvantage.This behaviour can result in serious consequences, e.g. the grade of zero on an assignment, loss ofcredit with a notation on the transcript (notation reads: “Grade of F assigned for academicdishonesty”), and/or suspension or expulsion from the university. For information on the varioustypes of academic dishonesty please refer to the Academic Integrity Policy, located ies-roceduresguidelines/The following illustrates only three forms of academic dishonesty: plagiarism, e.g. the submission of work that is not one’s own or for which other credit has beenobtained. improper collaboration in group work. copying or using unauthorized aids in tests and examinations.Authenticity / Plagiarism DetectionSome courses may use a web-based service (Turnitin.com) to reveal authenticity and ownership ofstudent submitted work. For courses using such software, students will be expected to submit theirwork electronically either directly to Turnitin.com or via an online learning platform (e.g. A2L, etc.)using plagiarism detection (a service supported by Turnitin.com) so it can be checked for academicdishonesty. Students who do not wish their work to be submitted through the plagiarism detectionsoftware must inform the Instructor before the assignment is due. No penalty will be assigned to a
MECHENG 4BF3Biofluid MechanicsDr. Z. Motamedstudent who does not submit work to the plagiarism detection software. All submitted work issubject to normal verification that standards of academic integrity have been upheld (e.g., on-linesearch, other software, etc.). For more details about McMaster’s use of Turnitin.com please go towww.mcmaster.ca/academicintegrity.Courses with an On-Line ElementSome courses may use on-line elements (e.g. e-mail, Avenue to Learn (A2L), LearnLink, web pages,capa, Moodle,ThinkingCap, etc.). Students should be aware that, when they access the electroniccomponents of a course using these elements, private information such as first and last names, usernames for the McMaster e-mail accounts, and program affiliation may become apparent to all otherstudents in the same course. The available information is dependent on the technology used.Continuation in a course that uses on-line elements will be deemed consent to this disclosure. If youhave any questions or concerns about such disclosure please discuss this with the course instructor.Online ProctoringSome courses may use online proctoring software for tests and exams. This software may requirestudents to turn on their video camera, present identification, monitor and record their computeractivities, and/or lock/restrict their browser or other applications/software during tests or exams.This software may be required to be installed before the test/exam begins.Conduct ExpectationsAs a McMaster student, you have the right to experience, and the responsibility to demonstrate,respectful and dignified interactions within all of our living, learning and working communities. Theseexpectations are described in the Code of Student Rights & Responsibilities (the “Code”). All studentsshare the responsibility of maintaining a positive environment for the academic and personal growthof all McMaster community members, whether in person or online.It is essential that students be mindful of their interactions online, as the Code remains in effect invirtual learning environments. The Code applies to any interactions that adversely affect, disrupt, orinterfere with reasonable participation in University activities. Student disruptions or behaviours thatinterfere with university functions on online platforms (e.g. use of Avenue 2 Learn, WebEx or Zoomfor delivery), will be taken very seriously and will be investigated. Outcomes may include restrictionor removal of the involved students’ access to these platforms.Academic Accommodation of Students with DisabilitiesStudents with disabilities who require academic accommodation must contact Student AccessibilityServices (SAS) at 905-525-9140 ext. 28652 or sas@mcmaster.ca to make arrangements with aProgram Coordinator. For further information, consult McMaster University’s AcademicAccommodation of Students with Disabilities policy.Requests for Relief for Missed Academic Term WorkMcMaster Student Absence Form (MSAF): In the event of an absence for medical or other reasons,students should review and follow the Academic Regulation in the Undergraduate Calendar“Requests for Relief for Missed Academic Term Work”.
MECHENG 4BF3Biofluid MechanicsDr. Z. MotamedAcademic Accommodation for Religious, Indigenous or Spiritual Observances (Riso)Students requiring academic accommodation based on religious, indigenous or spiritual observancesshould follow the procedures set out in the RISO policy. Students should submit their request to theirFaculty Office normally within 10 working days of the beginning of term in which they anticipate aneed for accommodation or to the Registrar's Office prior to their examinations. Students should alsocontact their instructors as soon as possible to make alternative arrangements for classes,assignments, and tests.Copyright and RecordingStudents are advised that lectures, demonstrations, performances, and any other course materialprovided by an instructor include copyright protected works. The Copyright Act and copyright lawprotect every original literary, dramatic, musical and artistic work, including lectures by Universityinstructors.The recording of lectures, tutorials, or other methods of instruction may occur during a course.Recording may be done by either the instructor for the purpose of authorized distribution, or by astudent for the purpose of personal study. Students should be aware that their voice and/or imagemay be recorded by others during the class. Please speak with the instructor if this is a concern foryou.Extreme CircumstancesThe University reserves the right to change the dates and deadlines for any or all courses in extremecircumstances (e.g., severe weather, labour disruptions, etc.). Changes will be communicated throughregular McMaster communication channels, such as McMaster Daily News, A2L and/or McMasteremail.
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Academic skills assistance, job search, volunteeringGH 110ext. 24254studentsuccess@mcmaster.caStudent Accessibility ServicesDisability services, assistive technology supportMUSC B107ext. 28652sas@mcmaster.caTutorOceanStudent to Student Tutoring ffice of Student Financial aid and ScholarshipsEmergency funding, government funds, OSAP assistance, scholarships, work programsGH 120ext. 24319https://registrar.mcmaster.ca/aid-awards/Food Collective Centre (FKA Mac Bread Bin)DOOFThe Food Collective Centre is a service run by students dedicated to cultivating stronger food systems in theMcMaster and surrounding community. (MSU centreNeighbour 2 NeighbourFood bank, community kitchen, community counselling, help with paying for utilities, and more. com/Barrett Centre for Crisis SupportTROPPUSSISIRCSTUDENT SUPPORTSCIMEDACAStudent Success CentreProvides a safe environment in the community and responds to the needs of individuals, 16 years of age orolder, who experience a mental health crisis and do not require a hospital stay. Confidential and freeservices 24/7/36524 Hour Crisis Line: 905-529-7878, Toll Free: 1-844-777-3571COAST (Crisis Outreach and Support Team)Hamilton’s crisis line is answered 24 hours a day, 7 days a week. The COAST mobile team, consisting of amental health worker, and a police officer, will respond to crisis calls between the hours of 8 a.m. and 1 a.m.d
MECHENG 4BF3 Biofluid Mechanics Dr. Z. Motamed Department of Mechanical Engineering McMaster University MECHENG 4BF3 (Biofluid Mechanics) Term 2 (Janua
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