Total Duration: 5.5-7 Years MBBS Program Course Syllabus

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Curriculum of MBBS (Just for international students)Credits and CoursesTotal Number of Credits: 220.35Basic Medical Sciences Stage: 87.25Fundamental of Clinical Medicine Stage: 34.6Clinical Clerkship Stage: 98.5Total Duration: 5.5-7 YearsMBBS program Course Syllabusfor International StudentsM.B.B.S.- 1th semesterNumber of quisiteTotalcredits1Tissue, Development & Function2.250.252.52Cell and Molecules3.00.753.753Anatomy of limbs1.51.53.04Medical Physics2.02.05Principles of Health Services2.02.06General English Language7General Persian Language5PsychologyTotal2.015.75 - 2.02.515.25

M.B.B.S. - 2nd semesterNumber of quisiteTotalcredits1Cardiovascular System3.251.04.252Respiratory System1.50.251.753Medical Genetic2.04Biochemistry1.55Family Health2.02.06Persian Language3.03.07Medical Terminology13.0Total16.252.0Cell andMolecules0.5General EnglishLanguage1.752.03.018.0M.B.B.S. - 3rd semesterNumber of quisiteTotalcredits1Gastrointestinal System2.00.752.752Endocrine Systems1.50.251.753Urinary System1.50.251.754Reproductive System1.50.51.755Nutrition2.02.06Information Technology2.02.07Physical Training11.01.09Devine Ethics2.02.010Introduction to Religion I2.02.0Total15.251.7517.0

M.B.B.S.- 4th semesterNumber of quisiteTotalcredits1Immunology2.50.53.02Nervous System2.750.53.253Special Senses1.00.251.254Anatomy of Head and dical Terminology II3.0MedicalTerminology I3.08Physical Training II1.0Physical TrainingI1.09Introduction to Religion II2.0Total17.251.02.02.7520M.B.B.S.- 5th semesterNumber of y3.01.04.03Principles of Epidemiology2.04Devine Texts2.02.08Persian Language (PersianMedical Terminology)3.03.0Total12.0Principles ofHealth Services2.02.017

M.B.B.S.- 6th semesterNumber of quisiteTotalcredits1Physiopathology of Rheumatologic(Muscle & Joint) Diseases1.761.762Physiopathology of RespiratorySystem2.02.03Physiopathology of Digestive System1.881.884Physiopathology of CardiovascularSystem2.02.05Physiopathology of Urinary System1.761.766Advance Pathology 12.03.07Pharmacology 12.02.08Clinical Immunology I1.01.014.414.4Total

M.B.B.S.- 7th semesterNumber of quisiteTotalcredits1Physiopathology of Endocrine System2.02.02Physiopathology of Blood System2.02.03Fundamentals of Clinical Surgery1.01.04Fundamentals of Clinical Pediatrics1.01.05Fundamentals of Clinical Neurology0.50.56Fundamentals of Clinical Psychiatry0.50.57Fundamentals of Infectious Disease1.01.08Pharmacology 22.01.03.09Advance Pathology 22.00.72.710Clinical Immunology 21.011Medical Practice0.51.01.512Basic Clinical Skills2.02.92.015.54.720.2Total1.0

M.B.B.S.- 8th semesterNumber of quisiteTotalcredits1Biostatistics1.01.02Clinical Epidemiology2.02.03Forensic Medicine & Toxicology2.02.04Internal Medicine5Medical Ethics2.0Total7.012.012.02.012.019.0M.B.B.S.- 9th semesterNumber of quisiteTotalcredits1General .03.04Neurosurgery1.0Total9.01.012.021.0

M.B.B.S.- 10th semesterNumber of quisiteTotalcredits1Infectious Diseases2.03.05.02Neurologic Diseases1.53.04.53Psychiatry1.53.04.54General Obstetrics and Gynecology4.06.010.0Total9.015.024.0M.B.B.S.- 11th semesterNumber of erequisiteTotalcredits1Pediatrics Diseases 14.02Pediatrics Diseases ology1.51.56Emergency Medicine1.51.516.521.5Total5.012.03.0

M.B.B.S.- 12th semesterNumber of quisiteTotalcredits1Otolaryngology3.03.02Health Training3.03.03Research Methods & Computer2.02.04Persian .B.S. ThesisNumber of equisiteTotalcreditsThesis6.06.0Total6.06.0

COURSE NAME: Cell and Molecules BlockNUMBER OF CREDITS: 3.0 (theory) – 0.75 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This is the first block of M.D. program in Tehran University of Medical Sciences. The Cellular andMolecular Biology Program fosters interactions among students and faculty, helping to broaden thestudents’ appreciation of diverse research opportunities and to encourage interdisciplinary thinkingin a highly collaborative atmosphere. This program has been an integrative force that aims to tietogether the various disciplines of genetics, biochemistry, microbiology, immunology, cell biology,and others. The goal is to train our students to examine scientific problems from many perspectivesthrough individualized, flexible programs of coursework and research. The biochemical pathways ofliving organisms are studied with a focus on metabolic processes. Topics include pathways linkingnutritional intake and energy yielding processes as well as the application of underlying. Broadcontent includes a study of the chemistry and reactions of constituents of living matter, includingcarbohydrates, lipids, proteins, nucleic acids, vitamins, coenzymes, and minerals. In addition, thechemistry and regulation of the reactions and processes of whole organisms will be examinedincluding: endocrinology, enzymology, nutrition, intermediary metabolism, and biochemicalmechanisms involved in select disease states.References1.2.3.Junqueira's Basic Histology. McGraw-Hill Medical 2010; 12th edition, chapters 1, 2, 3Guyton and Hall Textbook of Medical Physiology. Saunders 2011, 12th edition, chapters 4 & 5Cohen B.J. Medical terminology: an illustrated guide. Walter Kluwer/Lippincott Williams & Wilkins2008. 5th edition4. Devlin T.M. Textbook of Biochemistry with Clinical Correlation. John Wiley & Sons 2010; 7thedition5. Murray R. et al. Harpers Illustrated Biochemistry. McGraw-Hill Medical 2009; 28th edition6. Ganong's Review of Medical Physiology. McGraw-Hill Medical 2009; 23rd edition

Cell and Molecules (theory) subjectsSession TitleHrs.Introduction to Cell & Molecule2Water and buffer2Introduction to Histology2Cell4Amino acid Structure & Classification2Amino acids & proteins classification2Amino acids & proteins functions2Amino acids & proteins Hemoglobin2Carbohydrates Mono- & Di- Saccharides2Carbohydrates Glycoconjugates2Lipids & Lipoproteins Structure4Enzymes6Vitamins & Coenzymes2Water Soluble Vitamins2Fat soluble vitamins2Amino Acids Structure2DNA Replication2Molecular biology Transcription2Molecular biology Translation2Molecular biology Repair mechanisms2Molecular biology Regulation of gene expression2Membrane performances4Membrane Potential (Voltage)Total hrs.458

Cell and Molecules (practical) subjectsSession es2Spectrophotometer2DNA Total hrs.18

COURSE NAME: Tissue, Development & Function BlockNUMBER OF CREDITS: 2.25 (theory) – 0.25 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This is a lecture and laboratory course that examines the microanatomy of cells, tissues andorgans. Lectures illustrate the microstructure of major tissues and organs in relation to theirfunction. Laboratory exercises use the light microscope to study these components and makeuse of slides and electron micrographs for review and discussion. This lab-oriented programpresents the molecular biology and histology of normal cells, tissues and organ systems atvarious developmental functional stages. Students learn how individual cell functionsinteract with one another and how such interactions are accomplished from the tissue levelsto the organ levels. The course introduces molecular and control systems and preparesstudents for an understanding of normal (homeostasis) systems and pathological conditions.In addition, students learn how molecular building blocks are utilized for growth anddifferentiation, wound healing and tissue repair, defense mechanisms, and transfer ofhereditary characters.References1.2.3.4.Junqueira's Basic Histology. McGraw-Hill Medical 2010; 12th edition; chapters 4-10 and 12-13 and 18Langman's Medical Embryology. Lippincott Williams & Wilkins 2012, 12th edition; chapters 2-9, pages10-129Guyton and Hall Textbook of Medical Physiology. Saunders 2011, 12th edition, chapters 6, 7, 8Ganong's Review of Medical Physiology. McGraw-Hill Medical 2009; 23rd edition

Tissue, Development, and Function (theory) subjectsSession TitleHrs.Epithelial Tissue2Connective Tissue2Types of Connective & Adipose Tissue2Cartilage Tissue & Joints2Osseous Tissue & Ossification2Blood & Hematopoiesis2Muscular Tissue2Nervous Tissue4Definition for Neurotransmission& Neurotransmitters2Cell Signaling2Skin2Introduction to Embryology2Gametogenesis2Ovulation & Fertilization2Embryonic Period21st & 2nd Weeks of Embryonic Period23rd Weeks of Embryonic Period2Fetal Period2Placenta & Fetal Membranes2Congenital Malformations2Contraction of Skeletal Muscle2Excitation of Skeletal Muscle2Contraction of Smooth Muscle2Neuromuscular Transmission2Total hrs.50

Tissue, Development, and Function (practical) subjectsSession TitleHrs.Microscopes2Epithelial Tissue2Connective & Osseous Tissue2Blood smears and cell differentiation2Cartilage Tissue2Muscular Tissue2Nervous Tissue2Skin2Total hrs.16

COURSE NAME: Cardiovascular System BlockNUMBER OF CREDITS: 3.25 (theory) – 1.0 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This course provides instruction into the mechanisms of operation of the humancardiovascular system. Emphasis is placed on the integration of relevant principles fromanatomy, physiology, biochemistry, pathology, pharmacology, and microbiology withrespect to the behavior of the normal circulation and its responses to the stress of injury anddisease. Both expert-directed and student-directed methodologies will be employed in thismodule and a select set of clinical cases will be used to guide instruction. Circulatory systemswill present students with an integrated approach to the key supply chain and wastemanagement systems of the body. Students will follow the movement of oxygen from theenvironment to the tissues, and movement of waste products of metabolism along theopposite path, examining the coordinated roles of the lungs, heart and kidney in the controland regulation of these processes. Introduction to anatomy, histology, and pharmacologycontent will be incorporated into the course.References1.2.3.4.5.6.7.8.Drake R.L. Gray’s Anatomy for Students. Churchill Livingstone 2010; 2nd edition. pp 58-243 excluding:101-106, 128-130, 137-139, 159-176Junqueira's Basic Histology. McGraw-Hill Medical 2010; 12th edition. Chapters 11 & 14Langman's Medical Embryology. Lippincott Williams & Wilkins 2012; 12th edition. Chapter 13, pp:162- 201.Medical physiology, Guyton and hall. Saunders 2011, 12th edition. Chapters 9-12, Chapters 14-19, Chapter 20 (exception: methods for measuring cardiac output up to end) Chapter 21 (exception: ischemic heart disease up to end) Chapter 23 Chapter 23 Chapter 23Snell R.S. Clinical Anatomy by Systems. Lippincott Williams & Wilkins 2006 o Chapters 4 and 5 o Pages 94-95 o Page 271 (Thoracic duct) o Page 609 (Phrenic nerve) o Pages 569-571 (Vagus nerve)Snell R.S. Clinical Anatomy by Regions 2008; 8th edition.Ganong's Review of Medical Physiology. McGraw-Hill Medical 2010; 23rd edition. Chapters 5, 30-34Berne & Levy. Medical physiology. 2008. 8th edition. Chapters 15-19

Cardiovascular System (theory) subjectsSession TitleHrs.Vertebral Column, Ribs, & Sternum2Back2Thoracic Wall2Mediastinum & Heart2Heart2Superior & Posterior Mediastinum4Overview of Cardiovascular system2Histology of Circulatory System2Histology of Lymphatic & Immune System4Embryology of the Heart2Embryology of Vessels2Physiology of RBCs/WBCs and Plts6Action Potentials in Cardiac Muscle, Cardiac Cycle2Electrocardiogram2Blood Pressure, Heart Sounds2“Volume-Pressure Diagram” During the CardiacCycle2Physics Principles of Circulatory System4Control of Excitation and Conduction in the Heart2of Circulatory System2Vessels of Circulatory System2Circulatory System of Lymph & Capillaries2Central Cardiovascular Control2Special Circulatory2Total hrs.56

Cardiovascular System (practical) subjectsSession TitleHrs.Histology of Heart, Lymph, & Capillaries Arteries4Cell blood Count (RBC/WBC)4Hematocrits and Coagulation tests2Electrocardiogram2Blood Pressure, Heart Sounds2Osteology4Anatomy of Back4Thoracic Wall2Mediastinum & Heart4Superior & Posterior Mediastinum2Total hrs.30

COURSE NAME: Respiratory System BlockNUMBER OF CREDITS: 1.5 (theory) – 0.25 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This block integrates the basic sciences into a study of the pulmonary system in both healthand disease. Each of the basic science topics is incorporated into an integrated body ofknowledge utilizing both didactic and self-directed learning methods, and clinical models.References1.Drake R.L. Gray’s Anatomy for Students. Churchill Livingstone 2010; 2nd edition. 159-175 985-10292. Junqueira's Basic Histology. McGraw-Hill Medical 2010; 12th edition 298-3153. Langman's Medical Embryology. Lippincott Williams & Wilkins 2012, 12th edition. 201-20714. Guyton and Hall Medical physiology, 12th edition, 2011, chapters 37-41.5. Ganong's Review of medical physiology, 2010, 23rd edition, section VII, chapters 35-37.6. Berne & Levy physiology, 2010, 6th edition, section 5, chapters 20-257. Snell R.S. Clinical Anatomy by Systems. Lippincott Williams & Wilkins 20068. Snell R.S. Clinical Anatomy by Regions 2008; 8th edition

Respiratory System (theory) subjectsSession TitleHrs.Nasal Cavity2Pharynx & Larynx2Lung & Pleura2Histology of Respiratory System2Pulmonary Ventilation2Embryology of Respiratory System2Pulmonary Volumes and Capacities2Pulmonary circulation2Physical Principles of Gas Exchange2Transport of O2 and CO2 in Blood and Tissue Fluids2Regulation of Respiration2Total hrs.22Respiratory System (practical) subjectsSession TitleHrs.Histology of Respiratory system2Spirometery2Nasal Cavity, Pharynx & Larynx2Lung & Pleura2Applied Anatomy2Total hrs.10

COURSE NAME: Gastrointestinal System BlockNUMBER OF CREDITS: 2.0 (theory) – 0.75 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This required system-based block integrates the basic sciences into the study of the gastrointestinalsystem and metabolism in both health and disease. Each of the basic science topics is incorporatedinto an integrated body of knowledge utilizing both didactic and self-directed learning methods andclinical models.References1.2.3.4.Drake R.L. Gray’s Anatomy for Students. Churchill Livingstone 2010; 2nd edition. Chapter 4, pages246-355 and 366-381, chapter 5, pages 439-441, chapter 8, pages 1030-1060 and 985-998Junqueira's Basic Histology. McGraw‐Hill Medical 2010; 12th edition, Chapters 15-16, pages249-297Langman's Medical Embryology. Lippincott Williams & Wilkins 2009, 11th edition, chapter15, pages 208-231Guyton and Hall Textbook of Medical Physiology. Elsevier 2016, 13th edition, chapters 63-6465-66

Gastrointestinal System (theory) subjectsSession TitleHrs.Anatomy of Oral Cavity, Pharynx, & Esophagus2Histology of Oral Cavity2Histology of Salivary Glands & General Structure ofDigestive Tract2Abdominal Wall Regions & Inguinal Canal4Peritoneal Cavity & Abdominal Viscera2Abdominal Digestive Tract2Digestive Tract in Pelvis2Microanatomy of Digestive Tract2Histology of Accessory Glands of Digestive System2Vessels & Nerves of Digestive System2Embryology of Foregut2Embryology of Midgut & Hindgut2General Principles of GI System2Gastric Secretion, Salivary and Esophagus Secretions2Pancreatic, Small and Large Secretions2Bile Secretion, Gall Bladder, and Liver Functions2GI Motility, Digestion, and Absorption2Total hrs.38

Gastrointestinal System (practical) subjectsSession TitleHrs.Histology of Oral Cavity, Pharynx, & Esophagus2Histology of Digestive Tract (Stomach,Duodenum, Jejunum Ileum)2Histology of Digestive Tract in Pelvis2Anatomy of Oral Cavity, Pharynx & Esophagus2Abdominal Wall Regions & Inguinal Canal4Peritoneal Cavity & Abdominal Viscera2Abdominal Digestive Tract2Anatomy of Digestive Tract in Pelvis2Mesenteric and Inferacolin Vessels2Total hrs.20

COURSE NAME: Endocrine System BlockNUMBER OF CREDITS: 1.5 (theory) – 0.25 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:This block integrates the basic sciences into a study of the endocrine and reproductive systems inboth health and disease. Each of the basic science topics is incorporated into an integrated body ofknowledge utilizing both didactic and self-directed learning methods, and clinical models.References1.2.3.Guyton and Hall Textbook of Medical Physiology. Saunders 2011, 12th edition, chapter 27, page 339 chapter 28, pages 345-348 and 353-357 chapters 74-79Junqueira's Basic Histology. McGraw‐Hill Medical 2010; 12th edition, chapter 20, pages 348-370Langman's Medical Embryology. Lippincott Williams & Wilkins 2009, 11th edition, chapter 17, pages274-275 and 267-268, chapter 18, pages 303-304 and 316-317

Endocrine System (theory) subjectsSession TitleHrs.Anatomy, Histology & Embryology of Hypothalamus& Pituitary Gland2Anatomy, Histology & Embryology of Thyroid,Parathyroid, Adrenal Glands & Pancreatic Islands2Introduction to Physiology of Endocrine System2Biochemical Principles of Hormones2Hypothalamus and Posterior Pituitary2Anterior Pituitary2Insulin, Glucagon, and Diabetes Mellitus2Thyroid Metabolic Hormones2Adrenocortical Hormones2Parathyroid Hormone, Calcitonin, Vitamin D andBone2Biochemistry of Hypothalamus & Pituitary Gland2Biochemistry of Thyroid Hormones2Thyroid Metabolic Hormones2Biochemistry of Parathyroid Hormones & RegulationMechanism of Ca2 2Total hrs.28Endocrine System (practical) subjectsSession TitleHrs.Microscopic structure of Endocrine system Glands2Macroscopic structure of Endocrine system Glands2Body Mass Index Calculation2Total hrs.6

COURSE NAME: Reproductive System BlockNUMBER OF CREDITS: 1.25 (theory) – 0.5 (practical)COURSE TYPE: Theoretical and PracticalGENERAL AIMS and DESCRIPTION:In the reproductive system block, students will learn how to explain the cellular andanatomical components of reproduction and early development. These components includethe development of the reproductive track, development of gametes, fertilization, andformation of the germ layers, development of the embryonic environment, andendocrinology of the system. Students will learn the behaviors, attitudes, and psycho-socialfactors that accompany the physical changes of puberty during normal development, as wellas some of the psychiatric disorders that may emerge and disrupt normal developmentduring this period. Students will also become familiar with psychosocial treatments for preand postpartum psychiatric disorders. Finally, students will critically evaluate basic andclinical research in the field.References1. Drake R.L. Gray’s Anatomy for Students. Churchill Livingstone 2010; 2nd edition. Chapter 5, pages448-4962. Junqueira's Basic Histology. McGraw‐Hill Medical 2010; 12th edition, chapters 21-22, pages371-411, chapter 18, pages 316-331.3. Langman's Medical Embryology. Lippincott Williams & Wilkins 2009, 11th edition, chapter16, pages 243-259, chapter 21, pages 339-3444. Guyton and Hall Textbook of Medical Physiology. Saunders 2011, 12th edition, chapters 8083

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MBBS program Course Syllabus for International Students M.B.B.S.- 1th semester Subject Number of credits . 5 Dermatology 3.0 3.0 Total 4.0 9.0 13.0 M.B.B.S. Thesis Subject Number of credits Total . Ganong's Review of Medical Physiology. McGraw-Hill Medical 200

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