School Of Biochemistry And Immunology JS Immunology 2019–2020

School of Biochemistry and ImmunologyJS Immunology2019–2020

2019-2020SECTION 1 – HANDBOOK INFORMATIONTable Of Contents:Cover PageSection 1 - Handbook InformationSection 2 - Programme OverviewSection 3 - General Student Information & RegulationsSection 4 - Teaching & LearningSection 5 – Appendix, 2019/2020 Class informationCommon Abbreviations used throughout handbook:JS – Junior Sophister,SS – Senior Sophister,Imm – ImmunologyBC – BiochemistryMM – Molecular MedicineB&I – School of Biochemistry & ImmunologySoM – School of MedicineECTS – European Credit Transfer SystemMCQ – multiple choice questions212391428

2019-2020SECTION 2 – PROGRAMME OVERVIEWWelcome to Junior Sophister Immunology:Congratulations on choosing an exciting and dynamic subject area for your degree. Inthe last 20 years, Immunology has advanced so much and skills from all biomedical sciencesare now central to solving questions in Immunology, which has now been realized as central toall disease in our bodies. In Junior Sophister year, you will learn the basic functioning of theimmune system (BIU33220) and apply this to its most recognized function – fighting infection(BIU33240). To support this, you will also go more in depth on the fundamental processes inbiochemistry and cellular signalling (BIU33210) and molecular biology and genetics(BIU33240).As well as going in-depth in the area of Immunology through the 4 modules outlinedabove, you will develop your skills as a scientist – through the practical classes associated witheach module and through the Laboratory Methods module (BIU33030), which is designed tointroduce students to the problems associated with experimental design, analysis andquantitatively making sense of data and interpreting your results. The Research Skills module(BIU33020), which consists of a “mini-review” – an in-depth literature review on a topic inimmunology which will be directed by an academic staff member, will also involve quantitativeproblems – which again will develop analytical and data-handling skills, as well as increaseyour knowledge of the experimental techniques employed by School staff on an everydaybasis. All of this will prepare you for your final year research project in the Senior Sophisteryear.The Freshman years in College are very different to the Sophister years you are nowentering. They were preparatory years, whereas what you do now counts towards your degree.The ethos is also different. Over the Freshman years the class size can be large and theatmosphere impersonal. Despite this, you coped and obviously did well as you havesucceeded in obtaining a place in a dynamic School. However, the smaller class size nowmeans that teaching can be more interactive – feel free to ask questions and initiatediscussions during lectures. If you have not understood, assume that the lecturer has notexplained things properly. Above all, try to see lecturers in supportive, as well as directiveroles. In this School, you are allocated a tutor – a full-time academic staff member whom youwill meet regularly and who will advise you in a small group situation. You should embrace thisopportunity and see it as advantageous for you, not an imposition, although it means morework. There will also be tutorial sessions related to the practical classes which accompanyeach module, outlining key techniques and skills.The formal extended essay or mini-review, the practical assessment, as well as theessays written as part of the tutorials, will help you develop the organisation and style in writingneeded to get a good degree. In your future career you will need to present clear, wellstructured reports. Discuss your work and take cognisance of the comments made by the staffmember – they are as important as the mark. Poor exam technique is a feature of earlyundergraduate years, so now is a good time to deal with this ahead of your finals next year.Exam answers often read like summaries, not developed accounts of a topic. Do not assumethat the reader has a good knowledge of the subject and explain details properly. First andforemost, read the question being asked very carefully and be sure to address this question inyour answer. Always keep this in mind when you organise your answers and essays. Do notregurgitate pre-prepared essays and do not question spot from previous exam papers.This booklet will outline the content of each module for the Immunology course acrossboth Semesters, as well as the distribution of marks for the year. A detailed breakdown of the 43

2019-2020Exam Papers is also provided. We have made every effort to ensure that the informationprovided regarding lecture content, practical classes etc is correct. We may update some of theinformation as we go along during the year. CMIS/mytcd provides the official college timetable.Notice will be provided of any major changes, re-scheduled/cancelled lectures or classes, viae-mail and through the class representative – who you should elect promptly & makethemselves known to School staff.From myself and all the academic staff in the School, we look forward to meeting withyou during the year. You are the future of Immunology in this School and we embrace theopportunity to help you on this exciting journey.Frederick J Sheedy,Ussher Assistant Professor in ImmunologySchool of Biochemistry & ImmunologyCourse co-ordinator, JS Immunology degreefsheedy@tcd.ieSchool Contacts:Junior Sophister Course CoordinatorsImmunology: Dr Frederick Sheedy, Room 5.50 and email: fsheedy@tcd.ieBiochemistry: Dr Derek Nolan Room 5.06 and e-mail: denolan@tcd.ieMolecular Medicine: Dr James Murray, James.Murray@tcd.ieJunior Sophister Practical Coordinator / Blackboard Coordinator:Dr Audrey Carroll, Room 3.25 (enter via Practical Teaching Lab, 3.22) aucarrol@tcd.ieErasmus/International Student Coordinator:Dr Andrei Budanov, budanova@tcd.ieSenior Sophister Immunology Course Coordinator:Prof Clair Gardiner, gardinec@tcd.ieDirector of Undergraduate Teaching and Learning:Dr Aisling Dunne, Room 3.10 and e-mail: aidunne@tcd.ieSchool Office: Ms Una Murphy, Room 3.07 and email: murphyu1@tcd.ie4

2019-2020OVERVIEW OF JUNIOR SOPHISTER COURSE STRUCTURE AND ASSESSMENT:A Junior Sophister student must complete 60 ECTS credits in the year.The 60 ECTS credits translate into 600 marks that are distributed across the course as follows:1.Four 10 credit modules consisting of lectures and linked practicals. Each of thesemodules will be assessed by continuous assessment (30% weighting) and by an exampaper at the end of the semester (70% weighting). There will be a separate exam paperfor each module. Total marks for this component 400 marks2.A 10 credit research skills module covering literature skills (a minireview of a topicproposed by a member of staff), presentation skills (involving a short oral presentationof the minireview topic) and analysis of quantitative data (4 quantitative problemsessions and associated exams). This module will be assessed by continuousassessment across both semesters (100%).The continuous assessment component will be linked to the literature review and anelement associated with in-course exams linked to the problem sessions. Total mark forthis module 100 marks.3.A 5 credit laboratory skills module covering basic biochemical and immunologicallaboratory skills (practical sessions) and data handling lectures. This module will beentirely in-course assessed in semester 1. Total mark for this component 50 marks.4.All JS students are obliged to take a Broad Curriculum option (5 credits) all of which arein-course assessed & can are scheduled across both semesters. Total mark for thiscomponent 50 marks.In summary; there will be four exam papers in total; 2 at the end of Semester 1, 2 at the end ofSemester 2, (2 hours each), which will assess the ten-credit core modules associated withlectures. You should note that in-course assessment includes a laboratory-based practicalexam, MCQs and problem exams, as well as home-work elements (laboratory assessments,mini-review etc.).The Junior and Senior Sophister years are integrated and the Junior Sophister mark(including the mark for Broad Curriculum) will contribute 20% to your final degree mark.Importantly, the pass-mark for Junior Sophister Immunology is 40% but to progress to SeniorSophister year, students must obtain a minimum grade of 45% in JS year.The Junior Sophister Immunology course content, module-by-module with associated markweightings and methods of assessment are outlined in the next 2 pages. Further informationon course content and learning objectives is provided in the final “Teaching & Learning”section.5

mester2019-2020Semester BIU33210Biochemistry10 ECTS BI3129(100 marks)Practical 1Practical 2Practical 3Lab MCQTopicAlpha, beta, tertiary domain interactionsActive site architecturePost-translation modificationsProteins of the immune systemLecturerAmir KhanAmir KhanDavid FinlayJerrard HayesAisling Dunne &Cellular signallingEmma CreaghPaul Voorheis &Membrane proteins and the cytoskeletonDerek NolanGeneral module material (inc. Practicals) VariousEnzyme KineticsJames MurraycAMP assayDaniela ZistererBinding assayDaniela ZistererMaterial from practical classesVariousAssessmentMarksPaper 11 of 2 Questions20 marksPaper 11 of 2 Questions20 marksPaper 11 of 2 Questions20 marksPaper 1Short QuestionsWrite-upWrite-upWrite-upIn-class MCQ10 marks3 marks4 marks3 marks20 marksmesterSept-DecCodeBI3022BI3023TopicImmunology I - Components of ImmunityModuleImmunology II - Immunity in DiseaseBIU33220Immunology I & IICoreGeneral module material (inc. Practicals)Concepts inLectureMCQImmunology I materialImmunologyPhagocytosis10 ECTS Practical 1Practical2Dendritic cells(100 marks)Lab MCQMaterial from practical classesLecturerAssessmentMarksVariousPaper 21 of 2 Questions20 marksVariousPaper 21 of 2 Questions20 marksVariousPaper 21 other Q20 marksVariousPaper 2Short Questions10 marksVariousIn-class MCQ5 marksRachel McLoughlinWrite-up2.5 marksEd LavelleWrite-up2.5 marksVariousIn-class MCQ20 marksmesterSept-NovCodeLecturesTopicData HandlingLecturerAndrew McDonaldComputer LabPre-PracticalPracticalsLab ExamAll PracticalsLab MCQKinetics & Prism AnalysisSolutions & DilutionsLab Skills Experiments 1-4Practical ExaminationLab Book Notes & Record KeepingMaterial from practical classesJames MurrayNoirin Nic BhairdDerek NolanDerek NolanFrederick SheedyVariousModuleBIU33030LaboratoryMethods5 ECTS(50 marks)6AssessmentData Handling ExerciseIn-class MCQIn-class testWrite-upIn-class Write-upLab Book InspectionIn-class MCQMarks15 marks15 marks1 mark3 marks4 marks2 marks10 marks