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THURSDAY, JUNE 18, 20203 - Opening Program: Structural Heart Disease During the COVID-19 Era, Supported byEdwards Lifesciences3 - Opening Live Q&A3 - Episode 1: Most Frequently Used TAVR Systems, Supported by Edwards Lifesciences3 - Episode 1: A Deep Dive into Imaging for Mitral Intervention4 - Challenging Case 1: MV Intervention4 - Challenging Case 2: Tricuspid, LAA, or PFO Intervention4 - Challenging Case 3: TAVR-Complications4 - Challenging Case 4: MV Complications and Intervention5 - Challenging Case 5: TAVR – VIV5 - Challenging Case 6: TAVR – Clinical Topics5 - Featured Structural ResearchFRIDAY, JUNE 19, 20205 - Special Session I: Collaborators in TAVR — For New-To-TAVR Heart Teams6 - Episode 2: Newcomer TAVR Systems, Supported by Boston Scientific Corporation6 - Episode 2: MitraClip for DMR — Technique EssentialsSATURDAY, JUNE 20, 20206 - Episode 1: Late-Breaking Clinical Science (I)7 - Late-Breaking Clinical Science Connect Live Q&A (I)7 - Episode 3: TAVR in Younger & Lower Risk Patients, Supported by Edwards Lifesciences7 - Episode 3: Heart Team Decision-making in Complex DMR Cases, Supported by AbbottSUNDAY, JUNE 21, 20208 - Episode 2: Late-Breaking Clinical Science (II)8 - Late-Breaking Clinical Science Connect Live Q&A (II)8 - EPISODE II: Patient Navigation Through TAVR Care Pathway - During and Post COVID,Sponsored by Edwards Lifesciences8 - Episode 4: TAVR Controversies9 - Episode 4: Transcatheter Edge-to-Edge Repair for FMR9 - Mitral Connect Live Q&A: Transcatheter Valve in MAC in Mitral Bioprosthetic ValveFailureMONDAY, JUNE 22, 20209 - Episode 1: PFO Closure — Outcomes in Stroke Prevention9 - Episode 5: Alternative Vascular Access and Closure In TAVR10 - TAVR Connect Live Q&A (I): TAVR in Younger & Lower Risk Patients: Challenges,Opportunities, and Controversies, Supported by Edwards Lifesciences10 - Episode 1: Transcatheter Tricuspid Intervention — Patient Selection and Imaging,Supported by AbbottTUESDAY, JUNE 23, 202010 - Special Session II: Transcatheter Aortic Regurgitation Therapy11 - Episode 2: PFO Closure — Devices and Techniques11 - Episode 2: Transcatheter Leaflet Grasping for Tricuspid Intervention, Supported byAbbottWEDNESDAY, JUNE 24, 202011 - Episode 3: Current Controversies in PFO Closure12 - PFO Closure Connect Live Q&A: Current Controversies in PFO Closure12 - Episode 6: Strokes & Cerebral Embolic Protection12 - Episode 3: Transcatheter Tricuspid Repair vs. Replacement13 - Tricuspid Connect Live Q&A: Transcatheter Leaflet Grasping for TricuspidRegurgitationTHURSDAY, JUNE 25, 202013 - Episode 1: Fundamentals of LAA Closure13 - EPISODE I: How to Enable Patients with Severe Aortic Stenosis to Continue to BeReferred and Treated During the Current COVID Crisis, Sponsored by EdwardsLifesciences13 - Episode 1: Case Based Learning for the Heart Team: Coronary Artery Disease in TAVIPatients14 - Episode 7: TAVR Case Management Strategies14 - Episode 5: Heart Team Roundtable — Decision-Making in Transcatheter MitralRepairFRIDAY, JUNE 26, 202015 - Episode 2: Watchman Series15 - Episode 2: Low Risk TAVI Trials in the Real World: Where Are We in 2020?15 - Episode 8: New TAVR Hot Topics16 - Episode 6: Transcatheter Mitral Valve Replacement (TMVR)SATURDAY, JUNE 27, 202016 - Episode 3: Expert Roundtable — Beyond the Watchman16 - EPISODE I: How to Enable Patients with Severe Aortic Stenosis to Continue to BeReferred and Treated During the Current COVID Crisis, Sponsored by EdwardsLifesciences17 - EPISODE III: Women In Structural Heart (WISH) - Hot Debates 2020, Sponsored byAbbott and Edwards Lifesciences17 - Episode 9. TAVR in Aortic Bioprosthetic Valve Failure17 - Episode 7: Transcatheter Valve in MAC (ViMAC)SUNDAY, JUNE 28, 202018 - Episode 4: Master Roundtable Discussion — Complex LAA Occlusion Cases andComplications18 - LAA Closure Connect Live Q&A: Complex LAA Anatomy: Interventional Approach,Device Selection, and Complication Management18 - EPISODE IV: Evolut TAVR and the Cusp Overlap Implant Technique, Sponsored byMedtronic19 - EPISODE V: Tailoring Mitral Valve Repair: Contemporary Evidence DemonstratingImproved Patient Outcomes, Sponsored by Abbott19 - Episode 10: Bicuspid Aortic Valve Disease (BAV), Supported by Edwards Lifesciences19 - TAVR Connect Live Q&A (II): TAVR in Bioprosthetic Valve Failure and Bicuspid AorticValve Disease, Supported by Edwards Lifesciences20 - Episode 8: Transcatheter Treatment of Mitral Bioprosthetic Valve Failure20 - Closing Program Connect Live Q&A: Crystal Ball Predictions in Valvular Heart DiseaseTVT Connect 2020 - Structural Heart SummitLast Updated 06/26/2020 Page: 2

THURSDAY, JUNE 18, 2020Episode 1: Most Frequently Used TAVR Systems, Supported byEdwards Lifesciences-OPENING PROGRAM: STRUCTURAL HEARTDISEASE DURING THE COVID-19 ERA,SUPPORTED BY EDWARDS LIFESCIENCESTHURSDAY, JUNE 18, 202012:00 PM - 1:00 PMTBDThis session is not accredited.-Opening Program: Structural Heart Disease During the COVID-19 Era,Supported by Edwards Lifesciences12:00 PM - 12:30 PMSegment 1: Balloon-Expandable Sapien TAVR SystemModerators: John G. Webb Presenters: Susheel K. Kodali Virtual Discussants:Tamim M. Nazif, Philippe Pibarot, David A. WoodTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.8:00 AM - 8:20 AMSegment 1: Structural Interventions in the Covid-19 Era — Emphasis on theHeart TeamModerators: Martin B. Leon Presenters: Bernard Prendergast Virtual Discussants:Eberhard Grube, Robert J. Sommer8:20 AM - 8:40 AMSegment 2: Structural Interventions in the Covid-19 Era — Re-Affirming aPatient Centric ApproachModerators: Martin B. Leon Presenters: Susheel K. Kodali Virtual Discussants:Jeroen J. Bax, Eberhard GrubeOPENING LIVE Q&A12:30 PM - 1:00 PMSegment 2: Self-Expanding Evolut R/Pro TAVR SystemModerators: Jeffrey J. Popma Presenters: John K. Forrest Virtual Discussants:Eberhard GrubeEPISODE 1: A DEEP DIVE INTO IMAGING FORMITRAL INTERVENTION-Episode 1: A Deep Dive into Imaging for Mitral InterventionTHURSDAY, JUNE 18, 20204:00 PM - 5:00 PMTBDThis session is not accredited.-Opening Live Q&ATHURSDAY, JUNE 18, 20208:40 AM - 9:00 AMTBDThis session is not accredited.8:40 AM - 9:00 AMOpening Live Q&AModerators: Juan F. Granada Social Media Moderators: Mirvat Alasnag, AayshaCader, Jay Mohan Virtual Discussants: Alexandre Abizaid, Mamas Mamas,Bernard PrendergastEPISODE 1: MOST FREQUENTLY USED TAVRSYSTEMS, SUPPORTED BY EDWARDSLIFESCIENCES4:00 PM - 4:20 PMSegment 1: Echo Imaging in Mitral Intervention — Planning and GuidanceModerators: Mark Reisman Presenters: Paul A. Grayburn Virtual Discussants:Rebecca T. Hahn, Dee Dee Wang4:20 PM - 4:40 PMSegment 2: CT Imaging in Mitral InterventionModerators: Mark Reisman Presenters: Jonathon A. Leipsic Virtual Discussants:João L. Cavalcante, Dee Dee Wang4:40 PM - 5:00 PMSegment 3: Imaging Assessment of Technical Outcomes Post-MitralInterventionModerators: Mark Reisman Presenters: Federico M. Asch Virtual Discussants:Gorav Ailawadi, João L. Cavalcante, Rebecca T. Hahn, Dee Dee Wang-TVT Connect 2020 - Structural Heart Summit THURSDAY, JUNE 18, 2020Last Updated 06/26/2020 Page: 3

8:20 AM - 8:30 AMPercutaneous Vacuum-Assisted Thrombectomy of a Right Atrial Thrombus in aPatient with a Patent Foramen OvalePresenter: Craig BasmanCHALLENGING CASE 1: MV INTERVENTION-Challenging Case 1: MV InterventionTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.CHALLENGING CASE 3: TAVR-COMPLICATIONS-Challenging Case 3: TAVR-Complications8:00 AM - 8:10 AMTranscatheter Mitral Valve Lithotripsy (TMVL) as a Pretreatment to MitralValvuloplasty in Calcified Rheumatic Valve Stenosis.Presenter: Alok SharmaTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.8:10 AM - 8:20 AMICE-Guided Mitraclip: A Step-By-Step GuidePresenter: Jonathan Yap8:00 AM - 8:10 AMRare Complication After TAVR - Ventricular Septal DefePresenter: Gokul Mandala Reddy8:20 AM - 8:30 AMRole of Teleproctoring in Challenging and Innovative Structural InterventionsAmidst the COVID-19 Pandemic and BeyondPresenter: Sachin Goel8:10 AM - 8:20 AMA «Moving» TAVR : Supra-Aortic Vessel Stenting to Stabilize an EmbolizedAcurate NEO ValvePresenter: Matteo Casenghi8:30 AM - 8:40 AMUrgent MitraClip for Torrential Mitral Regurgitation Following Coronary ArteryBypass Graft SurgeryPresenter: Leor Perl8:20 AM - 8:30 AMCoreValve Transcatheter Aortic Valve Migration Complicated by CardiogenicShockPresenter: Trisha Marie Gomez8:30 AM - 8:40 AMFailed Basilica for TAVR With High Risk of Coronary ObstructionPresenter: Itshac Itsik Ben-dorCHALLENGING CASE 2: TRICUSPID, LAA, ORPFO INTERVENTION-Challenging Case 2: Tricuspid, LAA, or PFO InterventionTHURSDAY, JUNE 18, 20208:00 AM - 8:30 AMTBDThis session is not accredited.8:00 AM - 8:10 AMFirst In Human Use of a Novel Percutaneous Transcatheter Tricuspid CoaptationValve Device for Severe Tricuispid Regurgitation.Presenter: Stephen A. O'Connor8:10 AM - 8:20 AMTricuspid Valve-In-Valve Percutaneous Procedure in Radiolucent DegeneratedProsthesisTVT Connect 2020 - Structural Heart Summit THURSDAY, JUNE 18, 2020CHALLENGING CASE 4: MV COMPLICATIONSAND INTERVENTION-Challenging Case 4: MV Complications and InterventionTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.8:00 AM - 8:10 AMFailed Mitral Ring Annuloplasty Followed By Failed Transseptal Valve-In-RingProcedure : Treating With Simultaneous Transapical Valve-In-Valve andParavalvuler Leak ClosureLast Updated 06/26/2020 Page: 4

8:10 AM - 8:20 AMRight Coronary Artery Ostial Dissection During Transseptal Mitral Valve in ValveReplacement: Management of a Complex Case When it Gets More Complex.Presenter: Pablo Codner8:00 AM - 8:10 AMTranscatheter Aortic Valve Replacement as a Bridge to Surgical Aortic ValveReplacementPresenter: Mark Gajjar8:20 AM - 8:30 AMSevere Hemolysis After Transapical Closure of Mitral Perivalvular LeakRequiring Transeptal Reintervention.Presenter: Marcelo A. Aguero8:10 AM - 8:20 AMPatient With Both Coarctation and Aortic Stenosis and Very High SurgicalRisk.How Should We Manage This Type of Challeging Case?Presenter: luis fernandez gonzalez8:30 AM - 8:40 AMNovel Percutaneous Treatment of Mitral Patient-Prosthesis Mismatch withBioprosthetic Valve in Valve Replacement With Valve FracturePresenter: Sukhdeep Basra8:20 AM - 8:30 AMTranscatheter Aortic Valve Replacement (TAVR) of Rapidly Progressive AorticStenosis of a Bicuspid Valve-Containing Donor Heart.Presenter: Jelani Grant8:30 AM - 8:40 AM7 Year Follow Up of TAVR For Pure Aortic RegurgitationPresenter: Sanjay S. BhandariCHALLENGING CASE 5: TAVR – VIV-Challenging Case 5: TAVR – VIVTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.FEATURED STRUCTURAL RESEARCH-Featured Structural ResearchTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.8:00 AM - 8:10 AMTranscarotid VIV TAVR, Bioprosthetic Valve Remodeling and Closure of LVOTPseudoaneurysmPresenter: Keith B. Allen8:00 AM - 8:10 AMImpact of Balloon Pre-dilation on Clinical Outcomes and Valve HemodynamicPerformance Following TAVR in The PARTNER 3 TrialPresenter: Karim Al-Azizi8:10 AM - 8:20 AMValve-in-Ring TAVR in a Patient With a HeartWare VAD and Prior HAART AorticValve AnnuloplastyPresenter: Marysa Leya8:20 AM - 8:30 AMValve-in-Valve Transcatheter Aortic Valve Implantation for Failing SurgicalAortic Stentless Bioprosthesis: When “Half” Sizes MatterPresenter: Antonio Popolo Rubbio8:10 AM - 8:20 AMSafety Profile of an Intra-Annular Self-Expanding Transcatheter Aortic Valveand Next-Generation Low-Profile Delivery System: Pooled Analysis of 180 Highand Extreme Risk Subjects From Two Prospective Cohort StudiesPresenter: Bassem Chehab8:30 AM - 8:40 AMHeart Team Approach to a Challenging Case of Alternative Access in ProstheticAortic Valve DysfunctionPresenter: Pegah Zare8:20 AM - 8:30 AMEarly Clinical Outcomes With a Repositionable and Fully Retrievable AorticValve in The First 50 Patients Enrolled in The Respond Edge RegistryPresenter: Rajesh K. Kharbanda8:30 AM - 8:40 AMClinical and Echocardiographic Outcomes of Transcatheter Mitral Valve Repairin a Single Healthcare SystemPresenter: Zuyue WangCHALLENGING CASE 6: TAVR – CLINICALTOPICS-Challenging Case 6: TAVR – Clinical TopicsTHURSDAY, JUNE 18, 20208:00 AM - 8:40 AMTBDThis session is not accredited.TVT Connect 2020 - Structural Heart Summit FRIDAY, JUNE 19, 2020FRIDAY, JUNE 19, 2020-SPECIAL SESSION I: COLLABORATORS IN TAVR— FOR NEW-TO-TAVR HEART TEAMS-Last Updated 06/26/2020 Page: 5

Special Session I: Collaborators in TAVR — For New-To-TAVR HeartTeamsFRIDAY, JUNE 19, 20208:00 AM - 9:00 AMTBDThis session is not accredited.8:00 AM - 8:20 AMSegment 1: Foundations of TAVR — Technology, Patient Selection, andEvidenceModerators: Martin B. Leon Presenters: Michael J. Reardon Virtual Discussants:Jeffrey J. Popma, Dee Dee Wang12:40 PM - 1:00 PMSegment 3: The ACURATE Neo TAVR SystemModerators: Michael J. Reardon Presenters: Alexandre Abizaid VirtualDiscussants: Helge Möllmann, Thomas PilgrimEPISODE 2: MITRACLIP FOR DMR —TECHNIQUE ESSENTIALS-Episode 2: MitraClip for DMR — Technique EssentialsFRIDAY, JUNE 19, 20204:00 PM - 5:00 PMTBDThis session is not accredited.8:20 AM - 8:40 AMSegment 2: Building Your TAVR Program (and Heart Team)Moderators: Martin B. Leon Presenters: Kim Guibone Virtual Discussants: KendraJ. Grubb, Srinivas Iyengar4:00 PM - 4:15 PMSegment 1: MitraClip — Echo Screening and GuidanceModerators: Scott Lim Presenters: Richard Bae Virtual Discussants: George Gellert8:40 AM - 9:00 AMSegment 3: Maintaining & Accelerating Your TAVR ProgramModerators: Martin B. Leon Presenters: Jeffrey J. Popma Virtual Discussants:Hemal Gada, Antonie Keller Producers: Daniel Parker4:15 PM - 4:30 PMSegment 2: MitraClip — Step-by-step Technique and Assessment of OutcomesModerators: Scott Lim Presenters: Jason H. Rogers Virtual Discussants: RalphStephan von BardelebenEPISODE 2: NEWCOMER TAVR SYSTEMS,SUPPORTED BY BOSTON SCIENTIFICCORPORATION4:30 PM - 4:45 PMSegment 3: New Insights From COAPTModerators: Scott Lim Presenters: Gregg W. Stone Virtual Discussants: Michael J.Mack, Patrick M. McCarthy-Episode 2: Newcomer TAVR Systems, Supported by Boston ScientificCorporationFRIDAY, JUNE 19, 202012:00 PM - 1:00 PMTBDThis session is not accredited.12:00 PM - 12:20 PMSegment 1: The LOTUS Edge TAVR SystemModerators: Michael J. Reardon Presenters: Christopher U. Meduri VirtualDiscussants: Hemal Gada, Nicolas M. Van Mieghem12:20 PM - 12:40 PMSegment 2: The PORTICO TAVR SystemModerators: Michael J. Reardon Presenters: Raj Makkar Virtual Discussants:Azeem Latib, Lars SondergaardTVT Connect 2020 - Structural Heart Summit SATURDAY, JUNE 20, 20204:45 PM - 5:00 PMSegment 4: MitraClip — Device Evolution (Gen 4)Moderators: Scott Lim Presenters: Anita Asgar Virtual Discussants: William A.Gray, Robert M. KippermanSATURDAY, JUNE 20, 2020-EPISODE 1: LATE-BREAKING CLINICAL SCIENCE(I)-Episode 1: Late-Breaking Clinical Science (I)SATURDAY, JUNE 20, 20208:00 AM - 9:00 AMTBDThis session is not accredited.Last Updated 06/26/2020 Page: 6

8:00 AM - 8:15 AMSEGMENT 1: Real World Experience With The SAPIEN 3 Ultra: A PropensityMatched Analysis From The United StatesModerators: Sunil V. Rao Presenters: Tamim M. Nazif Virtual Discussants: J. DawnAbbott, Subhash Banerjee, David J. Cohen12:00 PM - 12:20 PMSegment 1: TAVR in Low-Risk Patients - Considerations and Knowledge GapsModerators: Patrick T. O'Gara Presenters: Bernard Prendergast VirtualDiscussants: Martin B. Leon, Michael J. Reardon12:20 PM - 12:40 PMSegment 2: The TAVR Durability ConundrumModerators: Patrick T. O'Gara Presenters: Michael J. Mack Virtual Discussants:Philippe Pibarot, John G. Webb8:15 AM - 8:30 AMSEGMENT 2: Valve-In-Surgical Valve With SAPIEN 3 For TAVR: PropensityMatched Analyses of Real-World DataModerators: Sunil V. Rao Presenters: Amr E. Abbas Virtual Discussants: J. DawnAbbott, Subhash Banerjee, David J. Cohen8:30 AM - 8:45 AMSEGMENT 3: TAVR With Self-Expandable Supra Annular Valves for FailedSurgical Bioprostheses: Insights From the TVT RegistryModerators: Sunil V. Rao Presenters: Guilherme Attizzani Virtual Discussants: J.Dawn Abbott, Subhash Banerjee, David J. Cohen8:45 AM - 9:00 AMSEGMENT 4: TAVR Using Supra Annular, Self-Expanding Valves in Low RiskPatientsModerators: Sunil V. Rao Presenters: Bruce J. Rutkin Virtual Discussants: J. DawnAbbott, Subhash Banerjee, David J. CohenLATE-BREAKING CLINICAL SCIENCE CONNECTLIVE Q&A (I)-12:40 PM - 1:00 PMSegment 3: TAVR in Low-Risk Patients: A Case Study for the Heart TeamModerators: Patrick T. O'Gara Presenters: Amisha Patel Virtual Discussants: RajMakkar, Robert L. Smith, John G. WebbEPISODE 3: HEART TEAM DECISION-MAKINGIN COMPLEX DMR CASES, SUPPORTED BYABBOTT-Episode 3: Heart Team Decision-making in Complex DMR Cases,Supported by AbbottSATURDAY, JUNE 20, 20204:00 PM - 5:00 PMTBDThis session is not accredited.Late-Breaking Clinical Science Connect Live Q&A (I)SATURDAY, JUNE 20, 20209:00 AM - 9:30 AMTBDThis session is not accredited.9:00 AM - 9:30 AMLate-Breaking Clinical Science Connect Live Q&A (I)Moderators: Sunil V. Rao Social Media Moderators: Mirvat Alasnag, AayshaCader, Amisha Patel, John Saxon Virtual Discussants: J. Dawn Abbott, SubhashBanerjee, David J. CohenEPISODE 3: TAVR IN YOUNGER & LOWER RISKPATIENTS, SUPPORTED BY EDWARDSLIFESCIENCES-Episode 3: TAVR in Younger & Lower Risk Patients, Supported byEdwards Lifesciences4:00 PM - 4:15 PMSegment 1: High Surgical Risk Barlow’s DiseaseModerators: Patrick M. McCarthy Presenters: Jason H. Rogers Discussants: ScottLim4:15 PM - 4:30 PMSegment 2: Surgical MV Repair FailureModerators: Michael J. Reardon Presenters: Kendra J. Grubb Virtual Discussants:Isaac George, Howard C. Herrmann4:30 PM - 4:45 PMSegment 3: Small Valve Area and Mitral CalcificationModerators: Scott Lim Presenters: Jason H. Rogers Virtual Discussants: VasilisBabaliaros, Jeremy Thaden4:45 PM - 5:00 PMSegment 4: HOCMModerators: Michael J. Reardon Presenters: Paul Sorajja Virtual Discussants: ChetRihalSATURDAY, JUNE 20, 202012:00 PM - 1:00 PMTBDThis session is not accredited.TVT Connect 2020 - Structural Heart Summit SATURDAY, JUNE 20, 2020Last Updated 06/26/2020 Page: 7

SUNDAY, JUNE 21, 20209:00 AM - 9:30 AMLate-Breaking Clinical Science Connect Live Q&A (II)Moderators: David J. Moliterno Social Media Moderators: Mirvat Alasnag,Aaysha Cader Virtual Discussants: Samir R. Kapadia, Julinda Mehilli, Gregg W.Stone-EPISODE 2: LATE-BREAKING CLINICAL SCIENCE(II)-Episode 2: Late-Breaking Clinical Science (II)SUNDAY, JUNE 21, 20208:00 AM - 9:00 AMTBDThis session is not accredited.8:00 AM - 8:15 AMSEGMENT 1: Functional Status and Outcomes After TMVr in HF and SecondaryMR: The COAPT TrialModerators: Stephan Windecker Presenters: Gennaro Giustino VirtualDiscussants: Samir R. Kapadia, Julinda MehilliEPISODE II: PATIENT NAVIGATION THROUGHTAVR CARE PATHWAY - DURING AND POSTCOVID, SPONSORED BY EDWARDSLIFESCIENCES-EPISODE II: Patient Navigation Through TAVR Care Pathway - Duringand Post COVID, Sponsored by Edwards LifesciencesSUNDAY, JUNE 21, 20202:00 PM - 3:00 PMTBDThis session is not accredited.8:15 AM - 8:30 AMSEGMENT 2: First Prospective RCT Assessing Incidence of Reduced LeafletMotion and its Clinical Impact Following TAVRModerators: Stephan Windecker Presenters: Hasan Jilaihawi Virtual Discussants:Samir R. Kapadia, Julinda Mehilli2:00 PM - 2:15 PMSEGMENT I: VCC/Structural Heart Manager ViewpointModerators: Mark J. Russo Presenters: Roseanne Palmer Virtual Discussants:Vijay Iyer, Douglas C. Shook, Alex Vasquez8:30 AM - 8:45 AMSEGMENT 3: SAPIEN 3 TAVR Versus Surgery in Intermediate-Risk Patients: APropensity Score Matched Analysis of 5-Year OutcomesModerators: Stephan Windecker Presenters: Susheel K. Kodali Virtual Discussants:Samir R. Kapadia, Julinda Mehilli2:15 PM - 2:30 PMSEGMENT II: Interventional Cardiologist ViewpointModerators: Mark J. Russo Presenters: Vijay Iyer Virtual Discussants: RoseannePalmer, Douglas C. Shook, Alex Vasquez8:45 AM - 9:00 AMSEGMENT 4: Incidence, Characteristics, Predictors, and Outcomes of SurgicalExplantation After TAVR: A Population-Based, Nationally RepresentativeAnalysisModerators: Stephan Windecker Presenters: Tsuyoshi Kaneko Virtual Discussants:Samir R. Kapadia, Julinda Mehilli2:30 PM - 2:45 PMSEGMENT III: Anesthesia ViewpointModerators: Mark J. Russo Presenters: Douglas C. Shook Virtual Discussants:Vijay Iyer, Roseanne Palmer, Alex Vasquez2:45 PM - 3:00 PMSEGMENT IV: Interventional Cardiologist ViewpointModerators: Mark J. Russo Presenters: Alex Vasquez Virtual Discussants: VijayIyer, Roseanne Palmer, Douglas C. ShookLATE-BREAKING CLINICAL SCIENCE CONNECTLIVE Q&A (II)-Late-Breaking Clinical Science Connect Live Q&A (II)SUNDAY, JUNE 21, 20209:00 AM - 9:30 AMTBDThis session is not accredited.EPISODE 4: TAVR CONTROVERSIES-Episode 4: TAVR ControversiesSUNDAY, JUNE 21, 202012:00 PM - 1:00 PMTBDThis session is not accredited.TVT Connect 2020 - Structural Heart Summit SUNDAY, JUNE 21, 2020Last Updated 06/26/2020 Page: 8

12:00 PM - 12:30 PMSegment 1: Cardiac Conduction Management IssuesModerators: Tamim M. Nazif Presenters: Josep Rodés-Cabau Virtual Discussants:Hemal Gada, Steven J. YakubovSUNDAY, JUNE 21, 20205:00 PM - 5:30 PMTBDThis session is not accredited.12:30 PM - 1:00 PMSegment 2: Valve Leaflet Thickening and Thrombosis IssuesModerators: Raj Makkar Presenters: Jonathon A. Leipsic Virtual Discussants:Jeffrey J. Popma, Lars Sondergaard5:00 PM - 5:30 PMMitral Connect Live Q&AModerators: Scott Lim Social Media Moderators: Aaysha Cader, Purvi ParwaniVirtual Discussants: Megan Coylewright, Gilbert H.L. Tang, Mathew WilliamsEPISODE 4: TRANSCATHETER EDGE-TO-EDGEREPAIR FOR FMR-MONDAY, JUNE 22, 2020-EPISODE 1: PFO CLOSURE — OUTCOMES INSTROKE PREVENTION-Episode 4: Transcatheter Edge-to-Edge Repair for FMREpisode 1: PFO Closure — Outcomes in Stroke PreventionSUNDAY, JUNE 21, 20204:00 PM - 5:00 PMTBDThis session is not accredited.MONDAY, JUNE 22, 20208:00 AM - 9:00 AMTBDThis session is not accredited.4:00 PM - 4:15 PMSegment 1: Transcatheter Edge-to-Edge for FMR — Patient Eligibility andTimingModerators: James B. B. Hermiller Jr Presenters: William T. Abraham VirtualDiscussants: Paul A. Grayburn, Milton Packer8:00 AM - 8:20 AMSegment 1: PFO — Updated Nomenclature and Anatomical ClassificationModerators: Megan Coylewright Presenters: Akram Y. Elgendy VirtualDiscussants: Scott E. Kasner8:20 AM - 8:40 AMSegment 2: PFO Closure — A New Era of Secondary Stroke PreventionModerators: Megan Coylewright Presenters: Steven R. Messe Virtual Discussants:Zahid Amin4:15 PM - 4:30 PMSegment 2: Transcatheter Edge-to-Edge for FMR — Imaging and HemodynamicGuidanceModerators: James B. B. Hermiller Jr Presenters: Thomas Smith VirtualDiscussants: Samir R. Kapadia, Randolph P. Martin8:40 AM - 9:00 AMSegment 3: Choosing the “Right” Stroke Patient for PFO ClosureModerators: Megan Coylewright Presenters: David E. Thaler Virtual Discussants:Iris Q. Grunwald, Lars Sondergaard4:30 PM - 4:45 PMSegment 3: MitraClip in FMR — Technical Approach and ConsiderationsModerators: James B. B. Hermiller Jr Presenters: Matthew J. Price VirtualDiscussants: Georg Nickenig, Steven J. Yakubov4:45 PM - 5:00 PMSegment 4: PASCAL in FMR — Technical Approach and ConsiderationsModerators: James B. B. Hermiller Jr Presenters: Neil P. Fam Virtual Discussants:Jörg Hausleiter, Scott LimEPISODE 5: ALTERNATIVE VASCULAR ACCESSAND CLOSURE IN TAVR-Episode 5: Alternative Vascular Access and Closure In TAVRMITRAL CONNECT LIVE Q&A: TRANSCATHETERVALVE IN MAC IN MITRAL BIOPROSTHETICVALVE FAILURE-Mitral Connect Live Q&A: Transcatheter Valve in MAC in MitralBioprosthetic Valve FailureTVT Connect 2020 - Structural Heart Summit MONDAY, JUNE 22, 2020Last Updated 06/26/2020 Page: 9

MONDAY, JUNE 22, 202012:00 PM - 1:00 PMTBDThis session is not accredited.12:00 PM - 12:15 PMSegment 1: TAVR: Transfemoral Access - Technique and ToolboxModerators: Isaac George Presenters: Prakash Krishnan Virtual Discussants: KeithB. Allen, Michael Rinaldi, Torsten P. VahlEPISODE 1: TRANSCATHETER TRICUSPIDINTERVENTION — PATIENT SELECTION ANDIMAGING, SUPPORTED BY ABBOTT-Episode 1: Transcatheter Tricuspid Intervention — Patient Selectionand Imaging, Supported by AbbottMONDAY, JUNE 22, 20204:00 PM - 5:00 PMTBDThis session is not accredited.12:15 PM - 12:30 PMSegment 2: TAVR: Trans-Axillary Access and Carotid AccessModerators: Isaac George Presenters: James M. McCabe Virtual Discussants:Keith B. Allen, Philippe Genereux, Prakash Krishnan, Michael Rinaldi, Torsten P.Vahl4:00 PM - 4:15 PMSegment 1: Tricuspid Regurgitation and Clinical Outcomes — Lessons from theHF FieldModerators: Rebecca T. Hahn Presenters: JoAnn Lindenfeld Virtual Discussants:Colin M. Barker, Daniel Burkhoff12:30 PM - 12:45 PMSegment 3: TAVR: Trans-Caval AccessModerators: Adam B. Greenbaum Presenters: Toby Rogers Virtual Discussants:Chandan Devireddy, Amir Kaki4:15 PM - 4:30 PMSegment 2: Patient Selection for Tricuspid Intervention — Lessons From SurgeryModerators: Rebecca T. Hahn Presenters: Patrick M. McCarthy VirtualDiscussants: Isaac George, Maurizio Taramasso12:45 PM - 1:00 PMSegment 4: TAVR - Large-Bore Vascular Closure Techniques and New DevicesModerators: Adam B. Greenbaum Presenters: David A. Wood Virtual Discussants:Philippe Genereux, Curtiss T. Stinis4:30 PM - 4:45 PMSegment 3: Transcatheter Tricuspid Intervention — Imaging EssentialsModerators: Rebecca T. Hahn Presenters: Paul A. Grayburn Virtual Discussants:Jonathon A. Leipsic, Yan TopilskyTAVR CONNECT LIVE Q&A (I): TAVR INYOUNGER & LOWER RISK PATIENTS:CHALLENGES, OPPORTUNITIES, ANDCONTROVERSIES, SUPPORTED BY EDWARDSLIFESCIENCES-TAVR Connect Live Q&A (I): TAVR in Younger & Lower Risk Patients:Challenges, Opportunities, and Controversies, Supported by EdwardsLifesciencesMONDAY, JUNE 22, 20201:00 PM - 1:30 PMTBDThis session is not accredited.1:00 PM - 1:30 PMTAVR Connect Live Q&A (I): TAVR in Younger & Lower Risk Patients: Challenges,Opportunities, and Controversies,TVT Connect 2020 - Structural Heart Summit TUESDAY, JUNE 23, 20204:45 PM - 5:00 PMSegment 4: Heart Team Roundtable — Imaging and Tricuspid Device SelectionModerators: Rebecca T. Hahn Presenters: Neil P. Fam Virtual Discussants: PatrickM. McCarthy, Maurizio TaramassoTUESDAY, JUNE 23, 2020-SPECIAL SESSION II: TRANSCATHETER AORTICREGURGITATION THERAPY-Special Session II: Transcatheter Aortic Regurgitation TherapyTUESDAY, JUNE 23, 202012:00 PM - 1:00 PMTBDThis session is not accredited.Last Updated 06/26/2020 Page: 10

Episode 2: Transcatheter Leaflet Grasping for Tricuspid Intervention,Supported by Abbott12:00 PM - 12:15 PMSegment 1: TAVR Indications and Potential for Native Pure ARModerators: Vinod H. Thourani Presenters: Michael J. Reardon VirtualDiscussants: Danny Dvir, Hendrik TreedeTUESDAY, JUNE 23, 20204:00 PM - 5:00 PMTBDThis session is not accredited.12:15 PM - 12:30 PMSegment 2: Current (Non-Dedicated) TAVR for Native Pure AR (With CaseExamples)Moderators: Vinod H. Thourani Presenters: Thomas Pilgrim Virtual Discussants:Azeem Latib, Raj Makkar4:00 PM - 4:15 PMSegment 1: Transcatheter Tricuspid Leaflet Grasping — Imaging Guidance andLimitationsModerators: Jörg Hausleiter Presenters: Edwin Ho Virtual Discussants: Charles J.Davidson, Dee Dee Wang12:30 PM - 1:00 PMSegment 3: Jena-Valve TAVR for Native Pure AR (With Case Examples)Moderators: Vinod H. Thourani Presenters: Torsten P. Vahl Virtual Discussants:Stephan Baldus, James M. McCabe4:15 PM - 4:30 PMSegment 2: Transcatheter Tricuspid Leaflet Grasping — Indications, Technique,and OutcomesModerators: Jörg Hausleiter Presenters: Paul Sorajja Virtual Discussants: Neil P.Fam, Susheel K. KodaliEPISODE 2: PFO CLOSURE — DEVICES ANDTECHNIQUES4:30 PM - 4:45 PMSegment 3: Featured Case — Torrential TR with Very Large Coaptation GapModerators: Jörg Hausleiter Presenters: Ralph Stephan von Bardeleben VirtualDiscussants: William A. Gray, Yan Topilsky-Episode 2: PFO Closure — Devices and TechniquesTUESDAY, JUNE 23, 20208:00 AM - 9:00 AMTBDThis session is not accredited.8:00 AM - 8:15 AMSegment 1: PFO Closure — Imaging and Technique EssentialsModerators: Robert J. Sommer Presenters: Brij Maini Virtual Discussants: FabianNietlispach, Frank E. Silvestry8:15 AM - 8:30 AMSegment 2: PFO Closure — Anatomical and Technical ConsiderationsModerators: Robert J. Sommer Presenters: Matthew J. Price Virtual Discussants:Bushra S. Rana, Richard Smalling8:30 AM - 8:45 AMSegment 3: PFO Closure — Anatomical Determinants of Device Selection (CaseBased)Moderators: Robert J. Sommer Presenters: Horst Sievert Virtual Discussants: MarkReisman, Harsimran Sachdeva Singh4:45 PM - 5:00 PMSegment 4: Featured Case — Torrential TR in Presence of Pacemaker LeadModerators: Jörg Hausleiter Presenters: Charles J. Davidson Virtual Discussants:Edwin Ho, Francesco MaisanoWEDNESDAY, JUNE 24, 2020-EPISODE 3: CURRENT CONTROVERSIES IN PFOCLOSURE-Episode 3: Current Controversies in PFO ClosureWEDNESDAY, JUNE 24, 20208:00 AM - 9:00 AMTBDThis session is not accredited.8:00 AM - 8:15 AMSegment 1: PFO Closure for Migraine Headache8:45 AM - 9:00 AMSegment 4: PFO Closure — Complications and Management (Case-Based)Moderators: Robert J. Sommer Presenters: Harsimran Sachdeva Singh VirtualDiscussants: John F. RhodesEPISODE 2: TRANSCATHETER LEAFLETGRASPING FOR TRICUSPID INTERVENTION,SUPPORTED BY ABBOTT-TVT Connect 2020 - Structural Heart Summit WEDNESDAY, JUNE 24, 2020Last Updated 06/26/2020 Page: 11

8:15 AM - 8:30 AMSegment 2: PFO Closure to Prevent Primary StrokeModerators: Jonathan M. Tobis Presenters: Brian K. Whisenant VirtualDiscussants: David E. Thaler12:00 PM - 12:15 PMSegment 1: Strokes After TAVR and Neuro-ARCModerators: Samir R. Kapadia Presenters: Alexandra J. Lansky VirtualDiscussants: Hemal Gada, Steven J. Yakubov8:30 AM - 8:45 AMSegment 3: Post-Closure Antithrombotic Therapy — Does It Matter?Moderators: Jonathan M. Tobis Presenters: Amar Krishnaswamy VirtualDiscussants: Clifford J. Kavinsky1

Segment 2: Self-Expanding Evolut R/Pro TAVR System Moderators: Jeffrey J. Popma Presenters: John K. Forrest Virtual Discussants: Eberhard Grube EPISODE 1: A DEEP DIVE INTO IMAGING FOR MITRAL INTERVENTION -Episode 1: A Deep Dive into Imaging for Mitral Intervention THURSDAY, JUNE 18, 2020 4

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