IGSCE Human Biology SAMS Booklet - XtremePapers

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IGCSEHuman BiologySample AssessmentMaterials (SAMs)Edexcel IGCSE in Human Biology (4HB0)First examination 2011

Edexcel, a Pearson company, is the UK’s largest awarding body, offering academicand vocational qualifications and testing to more than 25,000 schools, colleges,employers and other places of learning in the UK and in over 100 countriesworldwide. Qualifications include GCSE, AS and A Level, NVQ and our BTEC suite ofvocational qualifications from entry level to BTEC Higher National Diplomas,recognised by employers and higher education institutions worldwide.We deliver 9.4 million exam scripts each year, with more than 90% of exam papersmarked onscreen annually. As part of Pearson, Edexcel continues to invest in cuttingedge technology that has revolutionised the examinations and assessment system.This includes the ability to provide detailed performance data to teachers andstudents which help to raise attainment.We will inform centres of any changes to this issue. The latest issue can be found onthe Edexcel website: www.edexcel.org.uk.AcknowledgementsThis document has been produced by Edexcel on the basis of consultation withteachers, examiners, consultants and other interested parties. Edexcel acknowledgesits indebtedness to all those who contributed their time and expertise to itsdevelopment.Every effort has been made to contact copyright holders to obtain their permissionfor the use of copyright material. Edexcel will, if notified, be happy to rectify anyerrors or omissions and include any such rectifications in future editions.References to third-party material made in this document are made in good faith.Edexcel does not endorse, approve or accept responsibility for the content ofmaterials, which may be subject to change, or any opinions expressed therein.(Material may include textbooks, journals, magazines and other publications andwebsites.)Authorised by Roger BeardPrepared by Phil MyersAll the material in this publication is copyright Edexcel Limited 2008

ContentsIntroduction3Sample question papers5Human Biology Paper 17Human Biology Paper 235Sample mark schemes55General Marking Guidance57Human Biology Paper 159Human Biology Paper 269Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials1

2Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

IntroductionThese sample assessment materials have been prepared to support the specification.The aim of these materials is to provide students and centres with a generalimpression and flavour of the actual question papers and mark schemes in advance ofthe first operational examinations.Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials3

4Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Sample question papersHuman Biology Paper 17Human Biology Paper 235Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials5

6Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

SurnameInitial(s)Paper ReferenceCentreNo.CandidateNo.4 H B 00 1SignaturePaper Reference(s)4HB0/01Examiner’s use onlyEdexcel IGCSETeam Leader’s use onlyHuman BiologyHuman Biology Paper 1Question LeaveNumber BlankSample Assessment MaterialTime: 2 hours123Materials required for examinationNil4Items included with question papersNil5678910Instructions to CandidatesIn the boxes above, write your centre number, candidate number, your surname, initial(s) and signature.Check that you have the correct question paper.Answer ALL the questions. Write your answers in the spaces provided in this question paper.Some questions must be answered with a cross in a box ( ). If you change your mind about ananswer, put a line through the box ( ) and then mark your new answer with a cross ( ).Information for CandidatesThe marks for individual questions and the parts of questions are shown in round brackets: e.g. (2).There are 10 questions in this question paper. The total mark for this paper is 120.There are 28 pages in this question paper. All blank pages are indicated.Advice to CandidatesWrite your answers neatly and in good English.This publication may be reproduced only in accordance withEdexcel Limited copyright policy. 2008 Edexcel Limited.Printer’s Log. No.N35423AW850/4HB0/57570 2/2/2/Edexcel IGCSE in Human BiologyTotal*N35423A0128*Turn over Edexcel Limited 20087Sample Assessment Materials

LeaveblankAnswer ALL questions.1.For each of the questions (a) to (j), choose an answer A, B, C, D and put a cross ( ) in thebox. Mark only one answer for each question. If you change your mind about an answer,put a line through the box ( ) and then mark your new answer with a cross ( ).(a) The diagram shows a section through the human heart.CBDAWhich chamber pumps oxygenated blood to the body?ABCD(1)(b) Which process do plants use to make their food from tion(1)8Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank(c) The diagram shows a section of the human eye.CBDAWhich part of the eye detects light?ABCD(1)(d) In which of the following structures does the human foetus usually grow anddevelop?AvaginaButerusCoviductDovary(1)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials9

Leaveblank(e) The diagram shows a cell from the human body.In which part of the body would this type of cell be found?AskinBlining of a blood vesselClining of the tracheaDbrain(1)(f) The diagram shows a cell made in the human body.Name the type of cell.AspermBovumCneuroneDmuscle(1)10Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank(g) Follicle-stimulating hormone (FSH) is made by which of the following structures?AtestisBliverCpituitary glandDadrenal gland(1)(h) Which of the gases is given out by car exhausts and is poisonous?Acarbon monoxideBmethaneCnitrogenDCFCs(1)(i) Which structure in the human body excretes carbon dioxide?AliverBlungsCkidneyDskin(1)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials11

Leaveblank(j) The diagram shows a fermenter which is used to grow fungi which can produce asubstance that can kill other fungi.air hat is the name of this type of (1)Q1(Total 10 marks)12Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

LeaveblankThe diagram shows the variation in the thickness of the lining of the uterus and some ofthe events during the menstrual cycle.2.Thickness oflining of uterusEgg cell develops inovaryMenstrualperiod02468 10 12 14 16 18 20 22 24 26 28 30Time in daysStart ofmenstrualperiod(a) (i) During which days is the lining of the uterus decreasing in thickness?.(1)(ii) Describe what is happening to this lining.(1)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials13

Leaveblank(iii) During which days is the lining at its thickest?.(1)(iv) Give three reasons for the lining being thick during this time.1 .2 .3 .(3)(b) Explain on which days of the cycle pregnancy is unlikely to occur.(4)Q2(Total 10 marks)14Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank3.(a) The bar chart shows the number of cases of the sexually transmitted disease,gonorrhoea, affecting people of different ages in a country in one year.(i) How many cases of the disease were there during the year in men aged30–34?.(1)(ii) How many cases of the disease were there during the year in women aged20–24?.(1)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials15

Leaveblank(iii) Which age group has the greatest number of cases of the disease in males andfemales?.(1)(iv) Suggest one reason for this age group having the greatest number of cases.(1)(b) (i) Name one other sexually transmitted disease.(1)(ii) State three ways in which the spread of gonorrhoea can be reduced.1 .2 .3 .(3)Q3(Total 8 marks)16Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank4.A student tests some food samples for protein.(a) He uses the piece of apparatus shown below to measure the reagent.25cm32015105(i) Name this piece of apparatus.(1)(ii) He measures out 3 cm3 of the reagent.Draw a line on the diagram to show the level of the reagent.(1)(b) The student tested two foods, A and B, for protein.(i) Name a reagent he could use.(1)(ii) He obtained the following results. Complete the table below to show the coloursobtained.FoodColourConclusionAno proteinBprotein present(2)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials17

Leaveblank(c) The diagrams below show the apparatus used by a student to investigate the digestionof starch at two different temperatures. C Cthermometerthermometertest tube100100909080807070606050504040heatedwatertest tubeheatedwatermixture B ofstarch andhuman amylasemixture A ofstarch andhuman amylase(i) What is the temperature at which each starch and human amylase mixture isbeing incubated?A.B.(2)18Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank(ii) The student removed a small sample of the starch and amylase mixture from eachtest tube every two minutes. Each sample was tested for the presence of starch.The student wished to show the results of the tests in the form of a table.Draw a table, with the correct headings, that will allow the student to record histest results.(4)(iii) State in which of the two mixtures the starch would be digested most quickly andexplain why.(3)Q4(Total 14 marks)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials19

Leaveblank5.(a) Some people carry donor cards like the one shown.Organ /Tissue Donor CardI wish to donate my organs and tissues. I wish to give:any needed organs or tissuesonly the following organsand tissues:DonorSignatureWitnessWitnessDateThis means that when they die, their body parts can be given to people that needthem.The table gives the function of body parts that are commonly donated.Complete the table using words from the rDonated body partbreaks down toxic chemicalsfills with air during breathingbends light as it enters eyesecretes insulin(4)20Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank(b) (i) Name the final fluid produced by a normal kidney.(1)(ii) Name the blood vessel that supplies oxygenated blood to the normal kidney.(1)(c) A person who suffers kidney failure may be treated every few days by dialysis.This uses an artificial kidney machine. The diagram shows the working of a kidneymachine. In this machine a special solution flows round the outside of an inner tubewhich carries the patient’s blood.Special solution of glucose, salts and aminoacids at the concentration found in normal bloodBlood frompatient’sarteryBlood l IGCSE in Human BiologySpecial solution excess wastesfrom the blood Edexcel Limited 2008Sample Assessment Materials21

Leaveblank(i) Name one of the excess wastes leaving the apparatus in the special solution.(1)(ii) Explain why the contents of the special solution entering the apparatus must beat the same concentration as found in normal blood.(3)(iii) Describe the function of the partially permeable membrane.(2)(iv) In a normal kidney, which structure acts as the partially permeable membrane?.(1)(d) Long term treatment for kidney failure is for the person to have a kidney transplant.(i) State three advantages to a person having a transplant rather than continueddialysis treatment.1 .2 .3 .(3)22Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank(ii) One disadvantage of a transplant is the need to find a donor with a matchingtissue type. Why is this process important?.(2)Q5(Total 18 marks)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials23

Leaveblank6.(a) Complete the sentences using words from the list.diffusionvesiclessynaptic cleftsneurotransmitterselectrochemicalsynapseNerve impulses pass along an axon in the form of an .impulse. Nerve cells come very close to the ends of other nerve cells at gapscalled a . . Nerve impulses are able to pass acrossthese gaps because of chemical substances. These substances are knownas . , an example of which is acetylcholine. The impulsereaches a pre-synaptic membrane, which is separated from the post-synapticmembrane, by a small gap called a . . The acetylcholineis formed at the end of the pre-synaptic axon and is containedin . . When the acetylcholine is released, it passes fromthe pre-synaptic membrane to the post-synaptic membraneby . where it stimulates another impulse.(6)(b) Suggest why the release of acetylcholine requires large numbers of mitochondria tobe present in the pre-synaptic axon.(2)Q6(Total 8 marks)24Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank7.The diagram below shows an outline of the life cycle of an insect that is the vector of themalarial parasite.Mated female feeds on the bloodfrom an animalAdults mateAdultFemale layseggs in waterAirWaterLarvaEggsPupa(a) (i) Name the type of insect shown in the diagram.(1)(ii) What is meant by the term vector in this context?.(2)(iii) On the diagram, circle the stage at which malaria is passed on to a human.(1)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials25

Leaveblank(iv) Give two stages of the life cycle where control measures could be used to stopthe spread of malaria. In each case explain how the control measure would beeffective.Stage 1 .Explanation .Stage 2 .Explanation .(4)(b) Suggest two reasons why malaria is a difficult disease to control.1 .2 .(2)(c) There is evidence that global temperatures are increasing.Suggest two possible effects of increases in global temperature on the number ofcases of malaria.(2)Q7(Total 12 marks)26Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank8.The diagram below shows two muscles which move the human elbow joint.AB(a) (i) Name the two muscles A and B.A.B.(2)(ii) Name two types of synovial joint shown in the diagram.1 .2 .(2)(iii) Explain how the two muscles A and B cause movement of the forearm.(4)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials27

Leaveblank(b) The diagram below shows an elbow without cartilage.Explain why the person whose elbow is shown is likely to have painful and difficultmovement of the joint.(4)Q8(Total 12 marks)28Sample Assessment Materials Edexcel Limited 2008Edexcel IGCSE in Human Biology

Leaveblank9.Haemoglobin exists in two forms, normal haemoglobin and sickle-cell haemoglobin.The allele for normal haemoglobin is Hb and that for sickle-cell haemoglobin is HbS.The alleles are codominant where they exist in the genotype.(a) (i) State what is meant by the term genotype.(1)(ii) State what is meant by the term codominant.(2)(b) (i) Name the type of cells in which haemoglobin is found.(1)(ii) Describe the function of haemoglobin.(3)Edexcel IGCSE in Human Biology Edexcel Limited 2008Sample Assessment Materials29

Leaveblank(c) (i) A person with the allele HbS is resistant to malaria. Complete the table below,to show the possible genotypes of the children born to two sets of parents withgenotypes given.For each child state whether this genotype would be resistant to malaria or not.Part of the table has been completed for you.Genotype of parentsFatherMotherGenotypes of possiblechildrenResistance to ) Parents who have particular genotypes can produce children who all haveresistance to malaria but none of the children suffer from sickle-cell anaemia.State the genotypes of such parents.Parent 1 .

Edexcel, a Pearson company, is the UK’s largest awarding body, offering academic and vocational qualific

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