9th Annual Basic And Clinical Immunology For The Busy .

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9th Annual Basic and ClinicalImmunology for the BusyClinician:Immunopathogenesis and Treatment ofImmune Mediated Inflammatory Diseasesand the Immunologic Basis of WellnessFebruary 5 & 6, 2021Virtual SymposiumWhy attend?1. Timely overview of recent advances in basic and clinical immunology2. Case-based presentations focused on a targeted therapy perspective3. Unique session reviewing the scientific and immunologic basis of wellnessThis program has been endorsed by:Cleveland Society ofRheumatologyMedia Coverage by Healio RheumatologyRegister Today! ccfcme.org/clinical2021

OverviewJoin us for the 9th Annual Basic and Clinical Immunology for the Busy Clinician:Immunopathogenesis and Treatment of Immune Mediated Inflammatory Diseases and theImmunologic Basis of Wellness virtual symposium.This annual course is designed for busy clinicians looking for an opportunity to enhance theirdeclarative and procedural knowledge in the field of immunology, as it applies to patients withimmune mediated inflammatory diseases. Sessions include an initial remedial seminar onthe integrated immune response for those feeling they need a refresher on the basic conceptsof human immunology. A second session highlights immunologic advances (pathogenesis,diagnosis, biomarkers) in key autoimmune diseases. A third session applies this knowledge ina series of case based presentations by leaders in the field on how they approach such patientsfrom a targeted therapy perspective. Reference to treatment guidelines, as well as recent data onefficacy and safety, will be emphasized. The final session centers on how lifestyle and behavioraffect immune response and how patient education on lifestyle management can affect clinicaloutcomes, including quality of life and inflammation.Why Attend the Virtual Symposium? Learn from national and international experts in the practice of immunology Focus on the management of select diseases with our advanced, case-based presentations Earn CME and ABIM Maintenance of Certification Points Explore our virtual exhibit hallAfter completing this live stream activity, participants will be able to: Describe the how the COVID-19 pandemic has altered the scientific knowledge of theintegrated immune response and the clinical practice of immunology. Summarize the key recent research findings on basic and clinical immunology and definetheir impact on patient care. Review the available clinical data on immunotherapies and apply them to individualized careplans for patients with specific immunologic conditions. Analyze research on the immunologic effects of sleep, exercise, and strength and interpretthe potential clinical implications.Who Should Attend?The symposium is directed to rheumatologists, dermatologists, infectious disease physicians,allergists, clinical immunologists, as well as specialists in integrative medicine, preventivemedicine, wellness, primary care, and other health care professionals caring for patients withimmunologic diseases.

AgendaDay 1 - Friday, February 5, 202112:00 pm Welcome & IntroductionsLeonard H. Calabrese, DO, Cleveland Clinic, Activity DirectorSession I - Remedial Immunology Boot CampThis session provides a 30,000 foot view of the integrated immune system through thelens of COVID-19. It is most appropriate for those interested in a remedial introductionto the current concepts of the human immune response.12:05 pm Through the Lens of COVID19 - How we Recognize and DefendOurselves from Viral PathogensLeonard H. Calabrese, DO1:05 pmQuestion & Answer Session1:20 pmBreakSession 2 – Advances in Basic and Clinical Immunology in Select ImmuneMediated DiseasesThis session focuses on the most recent advances in the underlying immunology ofselect diseases including underlying immunobiology of select diseases, as it applies todiagnosis, management and therapeutic targeting.1:30 pm Psoriasis, Psoriatic Arthritis and SpondlyoarthritisDennis McGonagle, FRCPI, PhD2:00 pmAutoinflammatory Syndromes/Cytokine StormR. John Looney, MD2:30 pm Panel DiscussionDennis McGonagle, FRCPI, PhD, and John Looney, MD2:50 pm Yoga Break (non-CME)A tradition at our Boot Camp, for the past several years, is to break up the meeting withwellness activities. Judi Bar is the Lead Yoga Therapist and Yoga Program Manager,Center for Integrative Medicine, Cleveland Clinic. Judi is one of the first to hold sucha position in the country with a major medical institution. She is certified throughInternational Association of Yoga Therapist. Judi will wake us up from our computersand infuse mind-body activity to recharge our body and mind3:00 pmRheumatoid ArthritisWilliam F.C. Rigby, MD3:30 pmSLEGregg J. Silverman, MD4:00 pm Panel DiscussionWilliam F.C. Rigby, MD, and Gregg J. Silverman, MD4:20 pmAdjournDay 2 - Saturday, February 6, 2021Session 3 – Case Based Approaches to Select Immune Mediated Inflammatory DiseasesThis session focuses on management of immune mediated inflammatory diseases(IMIDS) with biologic therapeutics including biologics and targeted synthetic biologics.The presentations are clinically based and emphasize complex medical decision makingincorporating aspects of drug selection, sequencing, outcomes, toxicity and recentguidelines for each disease.7:55 amWelcome & Introductions8:00 amRheumatoid ArthritisWilliam F.C. Rigby, MD8:30 amSystemic Lupus ErythematosusR. John Looney, MD9:00 am Panel DiscussionWilliam F.C. Rigby, MD, and R. John Looney, MD9:30 amPsAM. Elaine Husni, MD, MPH10:00 amSpondlyoarthritisPhilip J. Mease, MD10:30 am Panel DiscussionM. Elaine Husni, MD, MPH, and Philip J. Mease, MD11:00 amYoga Break with Judi Bar (non-CME)11:15 amVasculitisAdam Brown, MD

11:45 amTargeted Therapy Conundrums in the Compromised HostCassandra Calabrese, DO12:15 pm Panel DiscussionAdam Brown, MD, and Cassandra Calabrese, DO12:35 pm1:05 pmLunch BreakKeynote Lecture Art and Medicine TBA (non-CME)Session 4 – Scientific/Immune Basis of WellnessAn integral part of the Boot Camp is to critically appraise the data on the immunologicbasis of wellness. This year, we are featuring world leaders in two domains of greatinterest, including the immune-exercise and the immune sleep axis. We also will unveilthe Immune Strength program.1:35 pmImmunology of SleepMichael R. Irwin, MD2:05 pmImmunology of ExerciseDavid C. Nieman, DrPH, FACSM2:35 pm Immune StrengthLeonard H. Calabrese, DO, and M. Elaine Husni, MD, MPH3:05 pm3:35 pmPanel DiscussionMichael R. Irwin, MD; David C. Nieman, DrPH, FACSM;Leonard H. Calabrese, DO, and M. Elaine Husni, MD, MPHClosing RemarksCreating better habits for amore resilient immune systemFacultyActivity DirectorLeonard H. Calabrese, DOProfessor of MedicineCleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityR.J. Fasenmyer Chair of Clinical ImmunologyDepartment of Rheumatic and Immunologic DiseasesOrthopaedic and Rheumatologic InstituteCleveland ClinicCleveland, OHFacultyAdam Brown, MDDepartment of Rheumaticand Immunologic DiseasesOrthopaedic andRheumatologic InstituteCleveland ClinicCleveland, OHMichael R. Irwin, MDCousins DistinguishedProfessor of Psychiatry andBiobehavioral SciencesDavid Geffen School ofMedicine at UCLALos Angeles, CADavid C. Nieman, DrPH,FACSMProfessor, Department ofBiology, College of Arts andScienceAppalachian State UniversityBoone, North CarolinaCassandra Calabrese, DODepartment of Rheumaticand Immunologic DiseasesOrthopaedic andRheumatologic InstituteCleveland ClinicCleveland, OHR. John Looney, MDProfessor of MedicineStephen I. RosenfeldProfessor of Allergy andClinical ImmunologyUniversity of RochesterRochester, NYM. Elaine Husni, MD, MPHDirector, Arthritis andMusculoskeletal TreatmentCenterVice Chair of RheumatologyDepartment of Rheumaticand Immunologic DiseasesOrthopaedic andRheumatologic InstituteCleveland ClinicCleveland, OHDennis McGonagle, FRCPI,PhDProfessor, University of LeedsSchool of MedicineLeeds, EnglandWilliam F.C. Rigby, MDVice-Chair, Department ofMedicineProfessor of Medicine &MicrobiologyThe Geisel School ofMedicine at DartmouthLebanon, NHPhilip J. Mease, MDDirector of RheumatologyResearchSwedish Health ServicesSeattle, WAGregg J. Silverman, MDAssociate Director, Division ofRheumatologyProfessor of Medicine andPathologyNYU School of MedicineNew York, NY

General InformationStudy ReferencesAccreditationThe Cleveland Clinic Foundation Center forContinuing Education is accredited by theAccreditation Council for Continuing MedicalEducation (ACCME) to provide continuingmedical education for physicians.Faculty presentations will be available online inPDF format on a password protected website.You will have access prior to the activity to allowyou to download or print the slides.The Cleveland Clinic Foundation Center forContinuing Education designates this internetlive activity for a maximum of 10.50 AMA PRACategory 1 Credits . Physicians should claimonly the credit commensurate with the extent oftheir participation in the activity.Participants will receive instructions to accessthe virtual symposium at least five days prior tothe conference.Live Stream AccessAmericans with Disabilities ActParticipants claiming CME credit from thisactivity may submit the credit hours to theAmerican Osteopathic Association for Category2 credit.American Board of Internal Medicine MOCSuccessful completion of this CME activity,which includes participation in the evaluationcomponent, enables the participant to earn upto 10.50 Medical Knowledge MOC points in theAmerican Board of Internal Medicine’s (ABIM)Maintenance of Certification (MOC) program.Participants will earn MOC points equivalentto the amount of CME credits claimed forthe activity. It is the CME activity provider’sresponsibility to submit participant completioninformation to ACCME for the purpose of grantingABIM MOC credit.Other Health Care ProfessionalsA certificate of participation will be provided toother health care professionals for requestingcredits in accordance with state nursingboards, specialty societies, or other professionalassociations.The Cleveland Clinic Foundation Center forContinuing Education fully intends to complywith the legal requirements of the Americanswith Disabilities Act. If you need assistance,please notify us at least two weeks prior to theactivity.Faculty DisclosureThe Cleveland Clinic Foundation Center forContinuing Education has implemented a policyto comply with the current Accreditation Councilfor Continuing Medical Education (ACCME)Standards for Commercial Support requiringresolution of all faculty conflicts of interest.Faculty declaring a relevant commercial interestwill be identified in the activity syllabus.InformationFor additional information about this activity,contact the Cleveland Clinic Center forContinuing Education.Website: ccfcme.org/Clinical2021Phone: 216.444.9990Register online at ccfcme.org/clinical2021Fee includes: access to virtual symposium and faculty PowerPoint presentations in PDFCategoryRegistration ratePhysician 175Non-Physician 100Resident*/Fellow*Corporate 0 200*Letter from program directoris required to receive thediscounted fee. If letter is notreceived two weeks prior tothe activity, the full physicianfee will be charged.Registration and CancellationIn case of cancellation, a full refund will be made if canceled by January 15, 2021. AfterJanuary 15, a 25 cancellation fee will be deducted from your refund. Email notification of yourcancellation by January 22, 2021 is required to process your refund. No refunds will be issuedafter January 22, 2021.For questions about registration or cancellation, email us at cmeregistration@ccf.org or call216.448.8710.Cleveland Clinic Center for Continuing Education reserves the right to cancel or postpone an activity atour sole discretion. In the unlikely event that this occurs, any registration fee(s) paid will be refunded. Beadvised that Cleveland Clinic is not responsible for related costs including airline tickets, hotel costs, orany similar fee penalties incurred as a result of any trip cancellations or changes.

Register Today! ccfcme.org/clinical2021Virtual SymposiumFebruary 5 & 6, 2021Immunopathogenesis and Treatment of ImmuneMediated Inflammatory Diseases and theImmunologic Basis of Wellness9th Annual Basic and ClinicalImmunology for the Busy Clinician:The Cleveland Clinic Foundation9500 Euclid Ave, TR204Cleveland, OH 44195NON-PROFIT ORG.U.S. PostagePAIDCleveland, OHPermit No. 1918

Overview Join us for the 9th Annual Basic and Clinical Immunology for the Busy Clinician: Immunopathogenesis and Treatment of Immune Mediated Inflammatory Diseases and the Immunologic Basis of Wellness virtual symposium. This annual course is designed for busy clinicians looking for an opportunity to enhance their

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