Knee Marketing Module

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Knee MarketingModuleInternal use only. Do not distribute.

Knee PortfolioU2 Total Knee SystemU2 PSA Revision KneeUSTARII Primary and RevisionHinge KneeUSTARII Limb Salvage System2Internal use only. Do not distribute.The U2 PSA (Posterior StabilizedAugmentable) Revision Kneesystem can be used with variousaugments and extension stems torestore joint stability and addressbone loss, allowing surgeons thepossibility for an optimal solutionfor each individual patient.

The U2 PSA Revision KneeSystemOffers a wide range of revisioncomponent options.Designed for improved in jointstability with an increasedconstrained geometry design.Features a patented screwlocking mechanism.3

PSA Knee System. Novel low-profile tibial baseplate design.Reduced 18 mm tibial stem length. Designed to allow use of the offset adaptor with a stem extension without cortex impingment.PSA RevisionKnee Systemtibial baseplate.18mmOther tibialbaseplates canhave longerlength. This couldpotentially lead tocorteximpingementPSA Revision Knee Systemtibial baseplate with offsetadaptor.Generic kneesystem tibialbaseplate.

PSA Knee System. Novel C-Ring locking screw for a ‘NoBack-out’ Screw Design.Built-in reinforced metal ring. Designed to reduce the potential for shear on thetibial insert.Built- inscrewReinforcedmetal ringCentralrecessPSA Revision Knee System.Cutaway of Tibial Insert andTibial baseplate.5Patent No. US9044327Anthony et al , Journals of the Mechanical Behavior of Biomedical Materials( 2 0 1 4 ) 1 – 5Cutaway of PSATibial insert andbaseplate construct.

PSA Knee System. Platform approach for additional Intra-operativeRevision Options.Consistent implant design. Designed to provide improved flexibility to convertintra-operatively to and from PSA Revision Knee and USTARII Hinge Knee system.Matching AP, ML and chamfer resections.Consistent box width.PSA RevisionKneePSA RevisionKneeUSTARIIPrimary andRevision HingeKneeUSTARIIPrimary andRevision HingeKnee61 Note.The PS box widths are constant for the U2 PS Primary PS, PSA Revision and USTARII Hinge Knee systems. The PS box depth and heights vary.

Revision Knee System. Competitive Comparison – Femoral Component.7UNITEDORTHOPEDICPSA REVISIONKNEEZIMMERBIOMET PERSONA REVISION KNEEZIMMER-BIOMET NEXGEN LEGACY LCCKREVISION KNEEZIMMER-BIOMET VANGUARD 360REVISION KNEEDEPUY ATTUNE REVISION KNEEDEPUY LCS COMPLETEREVISION KNEESTRYKER TRIATHLON REVISION KNEESMITH &NEPHEW LEGION REVISIONKNEEMEDACTA GMK REVISIONKNEEEXACTECH TRULIANT tChromiumCobaltChromiumOxidized ating OptionCobaltChromium# SIZES6137101078865ROM155 155 120 NANAN/AN/A155 N/AN/A(PS) I/EROTATION 3.7 N/A 2.0 15 2, 0.5 3 4.0 4, Zeroconstraint5N/AVaries based oninsertVaries based on insertVaries basedon insert 4 7, 28(PS) VARUS/VALGUSCONSTRAINT 1.4 N/A 1.25 Zero constraint2, 1.0. 31.25 4,51.25 6Varies based oninsertVaries based on insertVaries basedon insert 3 7, 1.58FEMORAL OFFSETADAPTOR OPTIONS2, 4 and 6 mm3 and 6 mm4.5 mm2.5, 5 and 7.5 mm2, 4, and 6 mmN/A2, 4, 6 and 8 mm2, 4, and 6 mm3, 5 mm2, 4, 6, or 8mmFEMORAL AUGMENTOPTIONSDistal in 4, 8, 12, and16 mm, Posterior in 4and 8 mmDistal and Posteriorin 5, 10 and 15mm1Posterior, Distal,Posterior/Distal, AnteriorPosterior, Distal,Posterior/Distal,AnteriorDistal andPosteriorDistal in 5, 10 and 15mm, Posterior in 5 and10 mmDistal in 5, 10and 15 mm,Posterior in 5 and10 mmDistal in 5, 10 and 15mm, Posterior in 5 and10 mmDistal in 4,8and 12 mm,Posterior in 5and 10 mmDistal andPosterior in 5to 30 mm in5mm options9N/A Information Not Available l ROM Range-Of-Motion l I/E Internal/External l VVC Varus Valgus Constraint1Not in smaller sizes l 2With Standard Vanguard SSK PS Bearing l 3With SSK PSC Bearing l 4Fixed Bearing l 5Rotating Platform l 6VVC l 7PSC Posterior Stabilized Constrained l 8CC Condylar Constrained9Augments are stackable

Revision Knee System. Competitive Comparison – Femoral Component.8UNITEDORTHOPEDICPSA REVISIONKNEEMICROPORT EVOLUTION REVISION KNEECORIN APEX REVISIONKNEEORTHODEVELOPMENT BKS REVISIONKNEEAESCULAP IMPLANT SYSTEMSCOLUMBUS ASREVISION tChromiumCobaltChromiumCobaltChromium,AST coating Option3# SIZES66N/A77ROM155 N/AN/AN/A130 (PS) I/EROTATION 3.7 4.0 1NA2N/AN/A 2.2 4 1.2 5(PS) VARUS/VALGUSCONSTRAINT 1.4 2.0 1NA2N/AN/ANo Stability4 1.0 / 0.4 5FEMORAL OFFSETADAPTOR OPTIONS2, 4 and 6 mm4 and 8 mmN/AN/AUp to 4mm Posteriorlyor AnteriorlyFEMORAL AUGMENTOPTIONSDistal in 4, 8, 12, and16 mm, Posterior in 4and 8 mmDistal and Posteriorin 4, 8 and 12 mmDistal and Posteriorin 5, 10 and 15 mmDistal in 4, 8 and 12mm, Posterior in 4and 8 mmDistal and Posterior in5, 10 mm (And 15 mmin some sizes)N/A Information Not Available l ROM Range-Of-Motion l I/E Internal/External l VVC Varus Valgus ConstraintCCK Constrained Condylar Knee l 2 CS Condylar Stabilizing Not Applicable (NA) for I/E Rotation and Varus/Valgus Constraint, has unique ‘toroid’ path allowing 15.0 of axial rotation l 3 AST Advanced coatingoption l 4 PS CS PS Condylar Stabilizing Medium Constrained l 5 PS CK High Constrained1

Revision Knee System. Competitive Comparison - Tibial Insert Component.9UNITEDORTHOPEDICPSA REVISIONKNEEZIMMERBIOMET PERSONA REVISION KNEEINSERT OPTIONSStandardConstrained IALZIMMER-BIOMET NEXGEN LEGACYLCCK REVISION KNEEZIMMER-BIOMET VANGUARD REVISIONKNEEDEPUY ATTUNE REVISIONKNEEDEPUY LCS COMPLETEREVISION KNEESTRYKER TRIATHLON REVISION KNEESMITH &NEPHEW LEGION REVISIONKNEEMEDACTA GMK REVISIONKNEEEXACTECH TRULIANT REVISION KNEEPersona RevisionCCK, PersonaCPS or PersonaPS BearingCCK, Legacy PSoptionsVanguard 360 SSKPS Bearing or SSKPSCFB and RP2,3RP PS and VVCPS, PSR, TSPS High-flex, PSConstrained, PSUltra-CongruentFixed, PS Fixed,Semi-ConstrainedFixed, Mobile,Ultra-CongruentMobilePS, PCS. CC9,11,13,15,18, 21, 25,30 mm10 thru 26 mmoptionsNA10 up to 24 mm in 2mm incrementsVaries depending oninsert typeVaries dependingon insert type9, 11, 13, 16, 19,22, 25, 28, 31mmVariesdepending oninsert typeVaries dependingon insert typeVaries dependingon insert typeUHMWPE,Highly Cross-linkedPoly(XPE),Vitamin- E Poly(EXPE)Vitamin-E andConventional(HXLPE)NAVivacit-E Vitamin Eand HXLPETechnology,Conventional(HXLPE)1Vivacit-E Vitamin Eand y,Conventional(HXLPE)1Conventional(HXLPE) andAdvanced (X3)UHMWPE,XLPEUHMWPENCM (UHMWPE)N/A Information Not Available l CCK Constrained Condylar Knee l CPS Constrained Posterior Stabilized l HXLPE Highly Cross-Lined Polyethylene l PSC Posterior Stabilized Constrained l FB Fixed Bearing lRP Rotating Platform l VVC Varus Valgus Constraint MB Mobile Bearing l PSR Posterior Stabilized Reinforced l TS Total Stabilizer l PSC Posterior Stabilized Constrained Stabilized l PCS PosteriorCondylar Stabilized l CC Condylar Constrained1Estimate only l 2FB Fixed Bearing l 3MB Mobile Bearing

Revision Knee System. Competitive Comparison - Tibial Insert Component.UNITEDORTHOPEDICPSA REVISIONKNEE10MICROPORT EVOLUTION REVISION KNEECORIN APEX REVISIONKNEEORTHODEVELOPMENT BKS REVISIONKNEEAESCULAP IMPLANT SYSTEMSCOLUMBUS ASREVISION KNEEINSERT OPTIONSStandardConstrained PSInsertCCK and CSN/APS and CKPS MC and PS 18, 21, 25,30 mm10, 12, 14, 17, 20,22, and 24mmN/A8, 10, 12, 14, 16, 18,20, 22, 24, 26, 28 and30110 to 32 mmMATERIALUHMWPE,Highly Cross-linkedPoly(XPE),Vitamin- E Poly(EXPE)UHMWPEN/AUHMWPE,Vitamin- E Poly (EVitalize )BETA SterilizedPolyethyleneN/A Information Not Available l CCK Constrained Condylar Knee l PS CS PS Condylar Stabilizing l PS CK Constrained1 CKInsert Options l MC Medium Constrained l HC High Constrained

Revision Knee System. Competitive Comparison– Tibial Baseplate Component.UNITEDORTHOPEDICPSA REVISIONKNEEZIMMER-BIOMET PERSONA REVISION KNEEZIMMER-BIOMET NEXGEN LEGACY LCCKREVISION KNEEZIMMER-BIOMET VANGUARD REVISION KNEEDEPUY ATTUNE REVISION KNEEDEPUY LCS COMPLETEREVISION KNEE3STRYKER TRIATHLON REVISION KNEESMITH &NEPHEW LEGION REVISIONKNEEMEDACTA GMK REVISIONKNEEEXACTECH TRULIANT REVISION KNEETIBIAL SIZES8991910928865INTERCHANGEABLE(FEMUR&TIBIA )Fullyinterchangeablewith Adult sizesLimited basedon Tibial InsertTypeLimited based on TibialInsert TypeComplete tibialfemoralinterchangeabilityLimited based onTibial Insert TypeLimited based onTibial Insert Type1 Size up, 1 SizedownLimited based onTibial Insert TypeLimited based onTibial Insert TypeLimited based on TibialInsert TypeTIBIALOFFSET ADAPTOROPTIONS2, 4 and 6 mm3 and 6 mmUp to 4.5mm2.5, 5 and 7.5 mmAvailableN/A2, 4, 6 and 8 mm2, 4, and 6 mm3, 5 mm2, 4, 6, or 8mmTIBIALAUGMENTOPTIONS5, 10, and 15 mm5, 10 and 15mm5, 10, 15 and 20mmand 30mm inTrabecular MetalVariousAvailable5,10 and 15 mm25 and 10 mm5, 10, and 15mm invarious angleoptions5 and 10 mm5, 10 and 15 mm 4N/A Information Not Available111Estimate only l 2M.B.T Revision Tray Option l 3LCS Complete Revision Knee shown with optional Sleeves implant component l 4 Augments are stackable

Revision Knee System. Competitive Comparison– Tibial Baseplate Component.UNITEDORTHOPEDICPSA REVISIONKNEEMICROPORT EVOLUTION REVISION KNEECORIN APEX REVISIONKNEEORTHODEVELOPMENT BKS REVISIONKNEEAESCULAP IMPLANT SYSTEMSCOLUMBUS ASREVISION KNEETIBIAL SIZES8Size 3 to 8 2N/A67INTERCHANGEABLE(FEMUR&TIBIA )Fullyinterchangeablewith Adult sizesN/AN/A1 Size up, 1 SizedownN/ATIBIALOFFSET ADAPTOROPTIONS2, 4 and 6 mmN/AN/AN/AUp to 6 mm Mediallyor LaterallyTIBIALAUGMENTOPTIONS5, 10, and 15 mm5, 10, and 15mmN/A5, 10, and 15mmin various angleoptions5, 10 and 15 mmN/A Information Not Available121Estimate only l 2 Includes Modular Keel with Medium and Large sizes

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