Chapter 6A Tour Of The Cell

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Chapter 6 A Tour of the CellThis chapter is a preview of those to follow. Therefore, many of the questions take a rather holisticapproach. Questions in the new edition reflect additions to the chapter and an increase ofApplication/Analysis and Synthesis/Evaluation questions. Where possible, some reflect integration withprior chapters on macromolecules.Multiple-Choice Questions1) When biologists wish to study the internal ultrastructure of cells, they most likely woulduseA) a light microscope.B) a scanning electron microscope.C) a transmission electronic microscope.D) A and BE) B and CAnswer: CTopic: Concept 6.1Skill: Knowledge/Comprehension2) The advantage of light microscopy over electron microscopy is thatA) light microscopy provides for higher magnification than electron microscopy.B) light microscopy provides for higher resolving power than electron microscopy.C) light microscopy allows one to view dynamic processes in living cells.D) A and BE) B and CAnswer: CTopic: Concept 6.1Skill: Knowledge/Comprehension3) A primary objective of cell fractionation is toA) view the structure of cell membranes.B) identify the enzymes outside the organelles.C) determine the size of various organelles.D) separate the major organelles so that their particular functions can be determined.E) crack the cell wall so the cytoplasmic contents can be released.Answer: DTopic: Concept 6.1Skill: Knowledge/Comprehension110

4) In the fractionation of homogenized cells using centrifugation, the primary factor thatdetermines whether a specific cellular component ends up in the supernatant or the pelletisA) the relative solubility of the component.B) the size and weight of the component.C) the percentage of carbohydrates in the component.D) the number of enzymes in the fraction.E) the presence or absence of lipids in the component.Answer: BTopic: Concept 6.1Skill: Knowledge/Comprehension5) Which of the following correctly lists the order in which cellular components will be foundin the pellet when homogenized cells are treated with increasingly rapid spins in acentrifuge?A) ribosomes, nucleus, mitochondriaB) chloroplasts, ribosomes, vacuolesC) nucleus, ribosomes, chloroplastsD) vacuoles, ribosomes, nucleusE) nucleus, mitochondria, ribosomesAnswer: ETopic: Concept 6.1Skill: Application/Analysis6) Quantum dots are small (15—30 nm diameter), bright particles visible using lightmicroscopy. If the dots can be specifically bound to individual proteins on a plasmamembrane of a cell, which of the following correctly describes the advantage of usingquantum dots in examining proteins?A) The dots permit the position of the proteins to be determined more precisely.B) The dots permit the average distance between the proteins to be determined moreprecisely.C) The dots permit the size of the proteins to be determined more precisely.D) The dots permit the motion of the proteins to be determined more precisely.E) The dots permit visualization of proteins interacting with lipids.Answer: DTopic: Concept 6.1Skill: Application/Analysis7) If a modern electron microscope (TEM) can resolve biological images to the nanometerlevel, as opposed to the best light microscope, this is due to which of the following?A) The focal length of the electron microscope is significantly longer.B) Contrast is enhanced by staining with atoms of heavy metal.C) Electron beams have much shorter wavelengths than visible light.D) The electron microscope has much greater ratio of image size to real size.E) The electron microscope cannot image whole cells at one time.Answer: CTopic: Concept 6.1Skill: Application/AnalysisChapter 6, A Tour of the Cell111

8) A biologist is studying kidney tubules in small mammals. She wants specifically to examinethe juxtaposition of different types of cells in these structures. The cells in question can bedistinguished by external shape, size, and 3-dimensional characteristics. Which would bethe optimum method for her study?A) transmission electron microscopyB) cell fractionationC) light microscopy using stains specific to kidney functionD) light microscopy using living unstained materialE) scanning electron microscopyAnswer: ETopic: Concept 6.1Skill: Synthesis/Evaluation9) A newspaper ad for a local toy store indicates that a very inexpensive microscope availablefor a small child is able to magnify specimens nearly as much as the much more costlymicroscope available in your college lab. What is the primary reason for the pricedifference?A) The ad agency is misrepresenting the ability of the toy microscope to magnify.B) The toy microscope does not have the same fine control for focus of the specimen.C) The toy microscope magnifies a good deal, but has low resolution and therefore poorquality images.D) The college microscope produces greater contrast in the specimens.E) The toy microscope usually uses a different wavelength of light source.Answer: CTopic: Concept 6.1Skill: Application/Analysis10) Why is it important to know what microscopy method was used to prepare the images youwish to study?A) so that you can judge whether the images you are seeing are of cells or of organellesB) so that you can make a judgment about the likelihood of artifacts having beenintroduced in the preparationC) so that you can decide whether the image is actually of the size describedD) so that you can know whether to view the image in color or notE) so that you can interpret the correct biochemical process that is occurringAnswer: BTopic: Concept 6.1Skill: Application/Analysis11) All of the following are part of a prokaryotic cell exceptA) DNA.B) a cell wall.C) a plasma membrane.D) ribosomes.E) an endoplasmic reticulum.Answer: ETopic: Concept 6.2Skill: Knowledge/Comprehension112Chapter 6, A Tour of the Cell

12) The volume enclosed by the plasma membrane of plant cells is often much larger than thecorresponding volume in animal cells. The most reasonable explanation for this observationis thatA) plant cells are capable of having a much higher surface-to-volume ratio than animalcells.B) plant cells have a much more highly convoluted (folded) plasma membrane thananimal cells.C) plant cells contain a large vacuole that reduces the volume of the cytoplasm.D) animal cells are more spherical, while plant cells are elongated.E) the basic functions of plant cells are very different from those of animal cells.Answer: CTopic: Concept 6.2Skill: Synthesis/Evaluation13) A mycoplasma is an organism with a diameter between 0.1 and 1.0 μm. What does its sizetell you about how it might be classified?A) It must be a single celled protist.B) It must be a single celled fungus.C) It could be almost any typical bacterium.D) It could be a typical virus.E) It could be a very small bacterium.Answer: ETopic: Concept 6.2Skill: Application/Analysis14) Which of the following is a major cause of the size limits for certain types of cells?A) the evolution of larger cells after the evolution of smaller cellsB) the difference in plasma membranes between prokaryotes and eukaryotesC) the evolution of eukaryotes after the evolution of prokaryotesD) the need for a surface area of sufficient area to allow the cellʹs functionE) the observation that longer cells usually have greater cell volumeAnswer: DTopic: Concept 6.2Skill: Knowledge/Comprehension15) Large numbers of ribosomes are present in cells that specialize in producing which of thefollowing molecules?A) lipidsB) starchesC) proteinsD) steroidsE) glucoseAnswer: CTopic: Concept 6.3Skill: Knowledge/ComprehensionChapter 6, A Tour of the Cell113

16) The nuclear lamina is an array of filaments on the inner side of the nuclear membrane. If amethod were found that could cause the lamina to fall into disarray, what would youexpect to be the most likely consequence?A) the loss of all nuclear functionB) the inability of the cell to withstand enzymatic digestionC) a change in the shape of the nucleusD) failure of chromosomes to carry genetic informationE) inability of the nucleus to keep out destructive chemicalsAnswer: CTopic: Concept 6.3Skill: Synthesis/Evaluation17) Recent evidence shows that individual chromosomes occupy fairly defined territorieswithin the nucleus. Given the structure and location of the following parts of the nucleus,which would be more probably involved in chromosome location?A) nuclear poresB) the nucleolusC) the outer lipid bilayerD) the nuclear laminaE) the nuclear matrixAnswer: ETopic: Concept 6.3Skill: Synthesis/Evaluation18) Under which of the following conditions would you expect to find a cell with apredominance of free ribosomes?A) a cell that is secreting proteinsB) a cell that is producing cytoplasmic enzymesC) a cell that is constructing its cell wall or extracellular matrixD) a cell that is digesting food particlesE) a cell that is enlarging its vacuoleAnswer: BTopic: Concepts 6.3, 6.4Skill: Application/Analysis19) Which type of organelle is primarily involved in the synthesis of oils, phospholipids, andsteroids?A) ribosomeB) lysosomeC) smooth endoplasmic reticulumD) mitochondrionE) contractile vacuoleAnswer: CTopic: Concept 6.4Skill: Knowledge/Comprehension114Chapter 6, A Tour of the Cell

20) Which structure is the site of the synthesis of proteins that may be exported from the cell?A) rough ERB) lysosomesC) plasmodesmataD) Golgi vesiclesE) tight junctionsAnswer: ATopic: Concept 6.4Skill: Knowledge/Comprehension21) The Golgi apparatus has a polarity or sidedness to its structure and function. Which of thefollowing statements correctly describes this polarity?A) Transport vesicles fuse with one side of the Golgi and leave from the opposite side.B) Proteins in the membrane of the Golgi may be sorted and modified as they move fromone side of the Golgi to the other.C) Lipids in the membrane of the Golgi may be sorted and modified as they move fromone side of the Golgi to the other.D) Soluble proteins in the cisternae (interior) of the Golgi may be sorted and modified asthey move from one side of the Golgi to the other.E) All of the above correctly describe polar characteristics of the Golgi function.Answer: ETopic: Concept 6.4Skill: Knowledge/Comprehension22) The fact that the outer membrane of the nuclear envelope has bound ribosomes allows oneto most reliably conclude thatA) at least some of the proteins that function in the nuclear envelope are made by theribosomes on the nuclear envelope.B) the nuclear envelope is not part of the endomembrane system.C) the nuclear envelope is physically continuous with the endoplasmic reticulum.D) small vesicles from the Golgi fuse with the nuclear envelope.E) nuclear pore complexes contain proteins.Answer: ATopic: Concept 6.4Skill: Knowledge/Comprehension23) The difference in lipid and protein composition between the membranes of theendomembrane system is largely determined byA) the physical separation of most membranes from each other.B) the transportation of membrane among the endomembrane system by smallmembrane vesicles.C) the function of the Golgi apparatus in sorting membrane components.D) the modification of the membrane components once they reach their final destination.E) the synthesis of lipids and proteins in each of the organelles of the endomembranesystem.Answer: CTopic: Concept 6.4Skill: Knowledge/ComprehensionChapter 6, A Tour of the Cell115

24) In animal cells, hydrolytic enzymes are packaged to prevent general destruction of cellularcomponents. Which of the following organelles functions in this compartmentalization?A) chloroplastB) lysosomeC) central vacuoleD) peroxisomeE) glyoxysomeAnswer: BTopic: Concept 6.4Skill: Knowledge/Comprehension25) Which of the following statements correctly describes some aspect of protein disposal fromprokaryotic cells?A) Prokaryotes are unlikely to be able to excrete proteins because they lack anendomembrane system.B) The mechanism of protein excretion in prokaryotes is probably the same as that ineukaryotes.C) Proteins that are excreted by prokaryotes are synthesized on ribosomes that arebound to the cytoplasmic surface of the plasma membrane.D) In prokaryotes, the ribosomes that are used for the synthesis of secreted proteins arelocated outside of the cell.E) Prokaryotes contain large pores in their plasma membrane that permit the movementof proteins out of the cell.Answer: CTopic: Concept 6.4Skill: Application/Analysis26) Tay-Sachs disease is a human genetic abnormality that results in cells accumulating andbecoming clogged with very large and complex lipids. Which cellular organelle must beinvolved in this condition?A) the endoplasmic reticulumB) the Golgi apparatusC) the lysosomeD) mitochondriaE) membrane-bound ribosomesAnswer: CTopic: Concept 6.4Skill: Application/Analysis27) The liver is involved in detoxification of many poisons and drugs. Which of the followingstructures is primarily involved in this process and therefore abundant in liver cells?A) rough ERB) smooth ERC) Golgi apparatusD) Nuclear envelopeE) Transport vesiclesAnswer: BTopic: Concept 6.4Skill: Knowledge/Comprehension116Chapter 6, A Tour of the Cell

28) Which of the following produces and modifies polysaccharides that will be secreted?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: DTopic: Concept 6.4Skill: Knowledge/Comprehension29) Which of the following contains hydrolytic enzymes?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: ATopic: Concept 6.4Skill: Knowledge/Comprehension30) Which of the following is a compartment that often takes up much of the volume of a plantcell?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: BTopic: Concept 6.4Skill: Knowledge/Comprehension31) Which is one of the main energy transformers of cells?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: CTopic: Concept 6.5Skill: Knowledge/Comprehension32) Which of the following contains its own DNA and ribosomes?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: CTopic: Concept 6.5Skill: Knowledge/ComprehensionChapter 6, A Tour of the Cell117

33) Which of the following contains enzymes that transfer hydrogen from various substrates tooxygen?A) lysosomeB) vacuoleC) mitochondrionD) Golgi apparatusE) peroxisomeAnswer: ETopic: Concept 6.5Skill: Knowledge/Comprehension34) Grana, thylakoids, and stroma are all components found inA) vacuoles.B) chloroplasts.C) mitochondria.D) lysosomes.E) nuclei.Answer: BTopic: Concept 6.5Skill: Knowledge/Comprehension35) Organelles other than the nucleus that contain DNA includeA) ribosomes.B) mitochondria.C) chloroplasts.D) B and C onlyE) A, B, and CAnswer: DTopic: Concept 6.5Skill: Knowledge/Comprehension36) The chemical reactions involved in respiration are virtually identical between prokaryoticand eukaryotic cells. In eukaryotic cells, ATP is synthesized primarily on the innermembrane of the mitochondria. Where are the corresponding reactions likely to occur inprokaryotic respiration?A) in the cytoplasmB) on the inner mitochondrial membraneC) on the endoplasmic reticulumD) on the inner plasma membraneE) on the inner nuclear envelopeAnswer: DTopic: Concept 6.5Skill: Knowledge/Comprehension118Chapter 6, A Tour of the Cell

37) A biologist ground up some plant leaf cells and then centrifuged the mixture to fractionatethe organelles. Organelles in one of the heavier fractions could produce ATP in the light,while organelles in the lighter fraction could produce ATP in the dark. The heavier andlighter fractions are most likely to contain, respectively,A) mitochondria and chloroplasts.B) chloroplasts and peroxisomes.C) peroxisomes and chloroplasts.D) chloroplasts and mitochondria.E) mitochondria and peroxisomes.Answer: DTopic: Concept 6.5Skill: Application/Analysis38) Which of the following are capable of converting light energy to chemical energy?A) chloroplastsB) mitochondriaC) leucoplastsD) peroxisomesE) Golgi bodiesAnswer: ATopic: Concept 6.5Skill: Knowledge/Comprehension39) A cell has the following molecules and structures: enzymes, DNA, ribosomes, plasmamembrane, and mitochondria. It could be a cell fromA) a bacterium.B) an animal, but not a plant.C) a plant, but not an animal.D) a plant or an animal.E) any kind of organism.Answer: DTopic: Concept 6.5Skill: Knowledge/Comprehension40) The mitochondrion, like the nucleus, has two or more membrane layers. How is theinnermost of these layers different from that of the nucleus?A) The inner mitochondrial membrane is highly folded.B) The two membranes are biochemically very different.C) The space between the two layers of the nuclear membrane is larger.D) The inner membrane of the mitochondrion is separated out into thylakoids.E) The inner mitochondrial membrane is devoid of nearly all proteins.Answer: ATopic: Concept 6.5Skill: Knowledge/ComprehensionChapter 6, A Tour of the Cell119

41) Why isnʹt the mitochondrion classified as part of the endomembrane system?A) It only has two membrane layers.B) Its structure is not derived from the ER.C) It has too many vesicles.D) It is not involved in protein synthesis.E) It is not attached to the outer nuclear envelope.Answer: BTopic: Concept 6.5Skill: Synthesis/Evaluation42) The peroxisome gets its name from its interaction with hydrogen peroxide. If a liver cell isdetoxifying alcohol and some other poisons, it does so by removal of hydrogen from themolecules. What, then, do the enzymes of the peroxisome do?A) combine the hydrogen with ATPB) use the hydrogen to break down hydrogen peroxideC) transfer the harmful substances to the mitochondriaD) transfer the hydrogens to oxygen moleculesAnswer: DTopic: Concept 6.5Skill: Application/Analysis43) How does the cell multiply its peroxisomes?A) They bud off from the ER.B) They are brought into the cell from the environment.C) They are built de novo from cytosol materials.D) They split in two after they are too large.E) The cell synthesizes hydrogen peroxide and encloses it in a membrane.Answer: DTopic: Concept 6.5Skill: Knowledge/Comprehension44) Motor proteins provide for molecular motion in cells by interacting with what types ofcellular structures?A) sites of energy production in cellular respirationB) membrane proteinsC) ribosomesD) cytoskeletonsE) cellulose fibers in the cell wallAnswer: DTopic: Concept 6.6Skill: Knowledge/Comprehension120Chapter 6, A Tour of the Cell

45) Cells can be described as having a cytoskeleton of internal structures that contribute to theshape, organization, and movement of the cell. Which of the following are part of thecytoskeleton?A) the nuclear envelopeB) mitochondriaC) microfilamentsD) lysosomesE) nucleoliAnswer: ATopic: Concept 6.6Skill: Knowledge/Comprehension46) Of the following, which cell structure would most likely be visible with a light microscopethat has been manufactured to the maximum resolving power possible?A) mitochondrionB) microtubuleC) ribosomeD) largest microfilamentE) nuclear poreAnswer: ATopic: Concept 6.6Skill: Knowledge/Comprehension47) Which of the following contain the 9 2 arrangement of microtubules?A) ciliaB) centriolesC) flagellaD) A and C onlyE) A, B, and CAnswer: DTopic: Concept 6.6Skill: Knowledge/ComprehensionChapter 6, A Tour of the Cell121

Use the following to answer the following questions. All three are involved in maintenance of cell shape.PropertyMicrotubules (tubulinpolymers)StructureHollow tubes; wallconsists of 13 columns oftubulin moleculesDiameter25 nm with 15-nm lumenMain functions Cell motilityMicrofilaments (actinfilaments)Two intertwined strandsof actin, each a polymer ofactin subunits7 nmCell motilityIntermediate filamentsFibrous proteinssupercoiled into thickercables8-12 nmAnchorage48) Tubulin is a dimer, made up of 2 slightly different polypeptides, alpha and beta. Given thestructure above, what is the most likely consequence to the structure of the microtubule?A) One ʺhalf-pipeʺ side of the tubule must be heavier in alpha and the other in betasubunits.B) One end of a microtub

Multiple-Choice Questions 1) When biologists wish to study the internal ultrastructure of cells, they most likely would use A) a light microscope. B) a scanning electron microscope. C) a transmission electronic microscope. D) A and B E) B and C Answer: C Topic: Concept 6.1 Skill: Knowledge/Comprehension

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