SEER Cancer Statistics Review 1975-2017

Table 29.1SEER Cancer Statistics Review 1975-2017Age-Adjusted and Age-Specific SEER Cancer Incidence Rates, 2013-2017aBy International Classification of Childhood Cancer(ICCC)b Group and Subgroupc and Age at DiagnosisIncluding myelodysplastic syndromes and Group III benign brain/CNS tumorsAll Races, Males and FemalesNational Cancer Instituteabcd-ICCC Group and Subgroup0-140-19All ICCC Groups CombinedExcluding Group III benign brain/CNS tumorsIncluding Group III benign brain/CNS tumorsd169.9185.7188.9210.7I Leukemia (includes myelodysplastic syndromes)I(a) Lymphoid leukemiaI(b) Acute myeloid leukemiaI(c) Chronic myeloproliferative diseasesI(d) Myelodysplastic syndrome and other myeloproliferativeI(e) Unspecified and other specified leukemias54.041.28.41.71.61.1II Lymphomas and reticuloendothelial neoplasmsII(a) Hodgkin lymphomaII(b) Non-Hodgkin lymphoma (except Burkitt lymphoma)II(c) Burkitt lymphomaII(d) Miscellaneous lymphoreticular neoplasmsII(e) Unspecified lymphomas 3.69.13.7-27.812.612.02.7-54.432.518.32.50.9III CNS and misc intracranial and intraspinal neoplasmsdIII(a) Ependymomas and choroid plexus tumorIII(b) AstrocytomaIII(c) Intracranial and intraspinal embryonal tumorsIII(d) Other gliomasIII(e) Other specified intracranial/intraspinal neoplasmsIII(f) Unspecified intracranial and intraspinal 2.462.22.913.72.55.036.22.0IV Neuroblastoma and other peripheral nervous cell tumorIV(a) Neuroblastoma and ganglioneuroblastomaIV(b) Other peripheral nervous cell -1.20.9-1.00.6-V Retinoblastoma4.43.332.38.20.5--VI Renal tumorsVI(a) Nephroblastoma and other nonepithelial renal tumorVI(b) Renal carcinomaVI(c) Unspecified malignant renal -1.80.81.0-1.91.7-SEER 21 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey,Georgia excluding ATL/RG, Idaho, New York and Massachusetts).International Classification of Childhood Cancer is based on ICD-O-3. International Classification of Childhood Cancer isbased on ICD-O-3. Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Shin HY, Hesseling P, Stiller CA.International Incidence of Childhood Cancer, Volume III. Lyon: International Agency for Research on Cancer, In press.Classifications are shown for invasive cases only except as noted. For ICCC groups and subgroups that include in situbehavior, only invasive cases are shown except as noted.Group III and Group III subgroups include benign brain/CNS tumors.Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).Statistic could not be calculated. Rate based on less than 16 cases for the time interval.

Table 29.1 - continuedSEER Cancer Statistics Review 1975-2017Age-Adjusted and Age-Specific SEER Cancer Incidence Rates, 2013-2017aBy International Classification of Childhood Cancer(ICCC)b Group and Subgroupc and Age at DiagnosisIncluding myelodysplastic syndromes and Group III benign brain/CNS tumorsAll Races, Males and FemalesICCC Group and Subgroup0-140-19 11-45-910-1415-19VII Hepatic tumorsVII(a) HepatoblastomaVII(b) Hepatic carcinomaVII(c) Unspecified malignant hepatic .20.8-1.51.3-VIII Malignant bone tumorsVIII(a) OsteosarcomaVIII(b) ChrondosarcomaVIII(c) Ewing tumor and related sarcomas of boneVIII(d) Other specified malignant bone tumorsVIII(e) Unspecified malignant bone 0.80.60.20.90.60.33.02.2-1.11.0--0.6-1.10.60.5IX SoftIX(a)IX(b)IX(c)IX(d)IX(e)X GermX(a)X(b)X(c)X(d)X(e)tissue and other extraosseous sarcomasRhabdomyosarcomaFibrosarcoma, peripheral nerve & other fibrousKaposi sarcomaOther specified soft tissue sarcomasUnspecified soft-tissue sarcomascell & trophoblastic tumors & neoplasms of gonadsIntracranial and intraspinal germ-cell tumorsExtracranial & extragonadal germ cell tumorsMalignant gonadal germ cell tumorsGonadal carcinomasOther and unspecified malignant gonadal tumorsXI Other malignant epithelial neoplasms and melanomasdXI(a) Adrenocortical carcinomaXI(b) Thyroid carcinomaXI(c) Nasopharyngeal carcinomaXI(d) Malignant melanomaXI(e) Skin carcinomaXI(f) Other and unspecified carcinomasdXII Other and unspecified malignant neoplasmsXII(a) Other specified malignant tumorsXII(b) Other unspecified malignant tumorsNational Cancer InstituteNot classified by ICCC0.20.2SEER 21 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey,Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey,Georgia excluding ATL/RG, Idaho, New York and Massachusetts).bInternational Classification of Childhood Cancer is based on ICD-O-3. International Classification of Childhood Cancer isbased on ICD-O-3. Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Shin HY, Hesseling P, Stiller CA.International Incidence of Childhood Cancer, Volume III. Lyon: International Agency for Research on Cancer, In press.cClassifications are shown for invasive cases only except as noted. For ICCC groups and subgroups that include in situbehavior, only invasive cases are shown except as noted.dIncludes in situ urinary bladder tumors.Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).Statistic could not be calculated. Rate based on less than 16 cases for the time interval.a

Table 29.2SEER Cancer Statistics Review 1975-2017Age-Adjusted SEER Cancer Incidence RatesaBy International Classification of Childhood Cancer(ICCC)b Selected Group and Subgroupc and Year of DiagnosisExcluding benign brain and myelodysplastic syndromesAll Races, Males and Females, Ages 0-19ICCC Group and SubgroupNational Cancer 2017163.1146.3159.3165.7181.6I LeukemiaI(a) Lymphoid leukemiaI(b) Acute myeloid .944.233.08.5II Lymphomas and reticuloendothelial neoplasmsII(a) Hodgkin lymphomaII(b,c,e) Non-Hodgkin 711.727.412.714.5III CNS & misc intracranial & intraspinal neoplasmsIII(a) Ependymomas and choroid plexus tumorIII(b) AstrocytomaIII(c) Intracranial and intraspinal embryonal tumorsIII(d) Other .75.75.129.52.514.56.35.631.52.916.26.05.5IV Neuroblastoma and other peripheral nervous cell tumorsIV(a) Neuroblastoma and V Retinoblastoma3.12.83.23.23.1VI Renal tumorsVI(a) Nephroblastoma and other nonepithelial renal tumor6.76.26.56.26.86.46.55.96.96.3VII Hepatic tumorsVII(a) Hepatoblastoma2.21.61.40.91.81.42.51.82.92.2VIII Malignant bone tumorsVIII(a) OsteosarcomaVIII(c) Ewing tumor and related sarcomas of X Soft tissue and other extraosseous sarcomasIX(a) 3X Germ cell & trophoblastic tumors & neoplasms of gonadsX(a) Intracranial and intraspinal germ-cell tumorX(c) Malignant gonadal germ cell 87.3XI Other malignant epithelial neoplasms and melanomasdXI(b) Thyroid carcinomaXI(d) Malignant .110.54.9All ICCC Groups Combinedabcd-SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).International Classification of Childhood Cancer is based on ICD-O-3. Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F,Dolya A, Shin HY, Hesseling P, Stiller CA. International Incidence of Childhood Cancer, Volume III. Lyon: International Agencyfor Research on Cancer, In press.Classifications are shown for invasive cases only except as noted. For ICCC groups and subgroups that include in situbehavior, only invasive cases are shown except as noted.Includes in situ urinary bladder tumors.Statistic could not be calculated. Rate based on less than 16 cases for the time interval.

Table 29.3SEER Cancer Statistics Review 1975-2017Age-Adjusted SEER Cancer Incidence Trends, 1975-2017aBy International Classification of Childhood Cancer(ICCC)b Selected Group and SubgroupcExcluding benign brain and myelodysplastic syndromesAll Races, Males and FemalesAges 0-14ICCC Group and SubgroupAll ICCC Groups CombinedAges 0-19% ChangeAPCAPCAPC1975-2017 1975-2017 1975-1996 1997-2017% ChangeAPCAPCAPC1975-2017 1975-2017 1975-1996 .7*0.7*1.0*0.6*0.9*1.3*0.7*0.50.6II Lymphomas and reticuloendothelial neo.II(a) Hodgkin lymphomaII(b,c,e) Non-Hodgkin 0*0.21.9*III CNS & misc intracranial & intraspinal neo.III(a) Ependymomas and choroid plexus tumorsIII(b) AstrocytomaIII(c) Intracranial and intraspinal embryonal tum.III(d) Other .8*0.8-0.5-0.1I LeukemiaI(a) Lymphoid leukemiaI(b) Acute myeloid leukemiaIV Neuroblastoma and other peripheralnervous cell tumorsIV(a) Neuroblastoma and 30.40.2-1.60.30.30.3V Retinoblastoma16.50.30.9-0.116.50.31.0-0.1VI Renal tumorsVI(a) Nephroblastoma and othernonepithelial renal 0.70.60.00.0VII Hepatic tumorsVII(a) 428.52.1*2.4*2.03.1*1.31.6VIII Malignant bone tumorsVIII(a) OsteosarcomaVIII(c) Ewing tum. and related sarcomas of .296.5-9.10.30.6*-0.11.0*1.7*0.30.30.80.1IX Soft tissue and other extraosseous sarcomasIX(a) 0.6*0.10.60.8X Germ cell & trophoblastic tum. & neo. of gonadsX(a) Intracranial and intraspinal germ-cell tum.X(c) Malignant gonadal germ cell nal Cancer InstituteXI Other malignant epithelial neo. and melanomasd81.01.7*0.23.1*103.41.6*0.72.8*XI(b) Thyroid carcinoma59.61.8*-0.13.8*166.12.4*0.44.3*XI(d) Malignant melanoma5.51.5*0.70.410.80.6*1.4-1.3The APC is the Annual Percent Change over the time interval.aSEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).bInternational Classification of Childhood Cancer is based on ICD-O-3. International Classification of Childhood Cancer isbased on ICD-O-3. Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Shin HY, Hesseling P, Stiller CA.International Incidence of Childhood Cancer, Volume III. Lyon: International Agency for Research on Cancer, In press.cClassifications are shown for invasive cases only except as noted. For ICCC groups and subgroups that include in situbehavior, only invasive cases are shown except as noted.dIncludes in situ urinary bladder tumors.*The APC is significantly different from zero (p .05)#The APC for 1997-2017 is significantly different from the APC for 1975-1996 (p .05).@The APC for 1997-2017 is significantly different from the APC for 1975-1996 (p .10).Statistic could not be calculated. Trend based on less than 10 cases for at least one year within the time interval.Neoplasms are abbreviated as neo. Tumors are abbreviated as tum.