School Of Chemistry And Molecular Bioscience BIOL213 .

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School of Chemistry and Molecular BioscienceBIOL213: Principles of BiochemistrySubject OutlineAutumn 2021On-CampusWollongongSubject InformationCredit Points: 6Pre-requisite(s): BIOL103 & CHEM101 and CHEM102 or CHEM104 & CHEM105Co-requisite(s): Subject Code to be entered from subject databaseRestrictions: As per subject databaseContact Hours: As per subject databaseSubject ContactsSubject Coordinator/LecturerName:Professor Heath EcroydLocation:Building 42, Room 312Telephone:61 2 4221 3443Email:heath ecroyd@uow.edu.auConsultation mode and times:Email for appointmentLecturerName:A/Prof Tracey KuitLocation:Building 43, Room 106Telephone:61 2 4221 4916Email:tracey kuit@uow.edu.auConsultation mode and times:Email for appointmentLecturerName:Dr Nikki CurthoysLocation:Building 43, Room G03Telephone:61 2 4221 3851Email:ncurthoy@uow.edu.auConsultation mode and times:Email for appointmentLecturerName:Dr Reece SophocleousLocation:To be confirmedTelephone:To be confirmedEmail:reeces@uow.edu.auConsultation mode and times:Email for appointmentHardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 1 of 17Last modified: 25 March 2021

Student Support and AdviceFor general enquiries please contact StudentHub 41:Location: Bldg 41 Level 1Telephone: 61 2 4221 3492Email: smah-students@uow.edu.auCopyrightCommonwealth of AustraliaCopyright Regulations 1969 2020 University of WollongongThe original material prepared for this guide is covered by copyright. Apart from fair dealing for the purposes of private study,research, criticism or review, as permitted under the Copyright Act, no part may be reproduced by any process without writtenpermission.Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 2 of 17Last modified: 25 March 2021

Table of ContentsSection A: General Information . 4Subject Learning Outcomes . 4Subject Description . 4Readings, References and Materials . 4Textbooks: . 4Prescribed Readings (includes eReadings) . 4Materials . 4Recommended Readings . 4Recent Changes to this Subject . 4Lecture Recordings . 5Your Privacy – Lecture Recording . 5Ethical Objection to the Use of Animal and Animal Products . 5Laboratory Safety Guidelines . 5List of Topics Covered . 6Section B: Assessment . 7Assessment Summary . 7Details of Assessment Tasks . 7Minimum Requirements for a Pass in this Subject . 8Minimum Student Attendance and Participation . 9Scaling. 9Late Submission . 9Late Submission Penalty – at 10% . 9Academic Consideration . 10Review and Appeal of Academic Decisions Policy . 10Supplementary Assessments. 10System of Referencing Used for Written Work . 10Submission of Assessments . 10Assessment Return . 10Retention of Submitted Work . 10Section C: General Advice . 11Student Consultation and Communication. 11Student Etiquette . 11eLearning Space . 11Use of Internet Sources . 11Lecture, Tutorial, Laboratory Times . 12Extraordinary Changes for the Subject after Release of the Subject Outline . 12Learning Analytics . 12The Assessment Quality Cycle . 12Academic Integrity Policy . 12Student Services and Support . 14UOW Grade Descriptors . 15University Policies . 16Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 3 of 17Last modified: 25 March 2021

Section A: General InformationSubject Learning OutcomesOn successful completion of this subject, students will be able to:1. Describe the major classes of macromolecules and their subunits;2. Describe the basic principles of enzyme function;3. Describe the information flow from DNA to protein;4. Perform the calculations necessary to relate physical amounts and concentrations ofbiochemicals;5. Interpret biochemical data and reach valid scientific conclusions;6. Display an understanding of the following experimental skills:i. Safe and responsible conduct in laboratoriesii. The ability to dispense and manipulate small (μl) volumes accuratelyiii. Use and understand the operation of a limited range of modern laboratory equipmentSubject DescriptionStructure and biological functions of proteins, nucleic acids, carbohydrates and lipids and theirsubunits. Membrane structure. Enzymes, their functions and their regulation. The central dogma ofMolecular Biology – from genes to proteins.Readings, References and MaterialsTextbooks:This subject uses the following text(s). Lehninger, Principles of Biochemistry, 7th Ed, International Edition, Nelson and Cox (2016)W.H. Freeman Macmillan Learning, New YorkPrescribed Readings (includes eReadings)NilMaterials UOW Approved CalculatorLaboratory Coat and safety glasses for the wet-practical laboratoriesRecommended ReadingsThe following references complement the prescribed readings and textbooks: Biochemistry (6th edition) Berg, Tymoczko & Stryer (574.192/49)Biochemistry (3rd edition) Mathews, van Holde & Ahern (574.192/88)Principles & Techniques of Biochemistry and Molecular Biology (6th edition) Wilson & Walker(574.192028/16)iGenetics (3rd edition) Russell (576.5/5)Recommended readings are not intended as an exhaustive list, students should use the Librarycatalogue and databases to locate additional resources.Recent Changes to this Subjecti.Changes to this subject have been made recently as a result of restrictions resulting from theCOVID-19 pandemic. These changes include:a. A decrease in the number of wet practicals delivered due to restrictions on thenumber of people allowed in the laboratory spaceb. The online delivery of the mid-session and final quizzesc. Amendments to the minimum requirements for a Pass in the subject (see below)ii.This subject has been adjusted to be delivered remotely for Autumn 2021 session.Please see further information on Remote Learning for Students on the following g/Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 4 of 17Last modified: 25 March 2021

Lecture RecordingsThe University of Wollongong supports the recording of lectures as a supplemental study tool, to providestudents with equity of access, and as a technology-enriched learning strategy to enhance the studentexperience.If you make your own recording of a lecture you can only do so with the explicit permission of the lecturerand those people who are also being recorded.You may only use recorded lectures, whether they are your own or recorded by the university, for yourown educational purposes. Recordings cannot be altered, shared or published on another platform,without permission of the University, and to do so may contravene the University’s Copyright Policy,Privacy Policy, Intellectual Property Policy, IT Acceptable Use Policy and Student Conduct Rules.Unauthorised sharing of recordings may also involve a breach of law under the Copyright Act 1969.All lectures in this subject will be recorded, when they are scheduled in venues that are equipped withECHO360 lecture recording technology, and made available via the subject Moodle site within 48 hoursYour Privacy – Lecture RecordingIn accordance with the Student Privacy & Disclosure Statement, when undertaking our normal teachingand learning activities, the University may collect your personal information. This collection may occurincidentally during the recording of lectures in equipped venues (i.e. when your identity can beascertained by your image, voice or opinion), therefore the University further advises students that: Lecture recordings are made available to students, university staff, and affiliates, securely onthe university’s Echo360 ALP (Active Learning Platform) via the eLearning platform Moodle; Recordings are made available only for the purpose for which they were recorded, for example,as a supplemental study tool or to support equity and access to educational resources; Recordings are stored securely for up to two years.If you believe your personal information has been collected in a recorded lecture you can approachyour Subject Coordinator and ask to view this information. If your personal information has beencollected and you do not want it used or stored you can request the recording be edited.The University is committed to ensuring your privacy is protected. If you have a concern about how yourpersonal information is being used or managed please refer to the University’s Privacy Policy or consultour Privacy webpage https://www.uow.edu.au/privacy/Ethical Objection to the Use of Animal and Animal ProductsIn order to achieve specific learning objectives, the use of animals, animal tissues, and or animalderived products (such as sera) is inherent and unavoidable. Students with conscientious objectionsto this use should not enrol in this subject.Students who intend to avoid a particular learning activity on the basis of conscientious objectionshould notify the subject coordinator in writing as soon as possible and not later than the end ofWeek 1 of the session. Students who do not participate in a particular learning activity are requiredto complete an alternative exercise (a CD-ROM is available) or attend the practical and "observe".The material involved is examinable and the prac must be written up and completed in yourworkbook. For further information, refer to aboratory Safety GuidelinesThe rules below are general rules that are required in laboratories. Before commencing your project you are to ensure that you understand specific proceduresfor the laboratory in which you work. You will need to fill out a risk assessment form before commencing any experiments (conferwith your laboratory supervisor). Never use any equipment or attempt any experiment without checking the safety implicationswith your laboratory supervisor or experienced delegated laboratory worker. Undergraduate students are not permitted to work after hours unless there is appropriateapproval and supervision.Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 5 of 17Last modified: 25 March 2021

List of Topics CoveredThe following are examples of the topics to be covered in this course. This is not an exhaustive listand will be subject to change. Amino acids: properties and functional groupsProtein structure and separation of proteinsCarbohydrates and glycobiologyNucleotides and nucleic acidsLipids and membrane structure and functionGenes and chromosomesReplication in prokaryotes and eukaryotesTranscription in prokaryotes and eukaryotesTranslation and protein modificationsProtein Function and ligand bindingEnzymes and bioenergeticsEnzyme Kinetics and regulationA Timetable of Topics will be available from the eLearning site in week 1 of session.Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 6 of 17Last modified: 25 March 2021

Section B: AssessmentAssessment SummaryAssessment ItemForm of AssessmentDue DateAssessment 1Practical pre-lab andpost-lab online quizzesAssessment 2Mid-session theory quizPre-lab quizzesdue before theprac class; Postlab quizzes due 34 days after theprac classWeek 6Assessment 3Assessment 4Electronic lab notebookworksheetPractical quizAt the end of theprac classWeek 12Assessment 5Final theory quizDuring examperiodReturn/FeedbackDue dateWithin 21 days ofdue dateWeightingWithin 21 days ofdue dateWithin 21 days ofdue dateWithin 21 days ofdue dateRelease ofresultsTotal Marks20%15%15%10%40%100%Details of Assessment TasksAssessment tasks will be marked using explicit criteria that will be provided to students prior tosubmission.Assessment 1Due DateWeightingSubmissionType of CollaborationLengthDetailsStyle and formatSubject LearningOutcomesMarking CriteriaAssessment 2Due DateWeightingSubmissionType of CollaborationLengthDetailsStyle and formatSubject LearningOutcomesMarking CriteriaPractical pre-lab and post-lab quizzesPre-lab quizzes due before the prac class; Post-lab quizzes due 3-4 daysafter the prac class15%OnlineIndividual AssessmentTo be completed before and following each prac classWill contain experimental data, calculations and quiz-style questionspertaining to that week’s practical class.Online quiz questions4, 5, 6Marked against a standardised answer sheetMid-session theory quizWeek 620%OnlineIndividual Assessment45 minMultiple choice and short answer questions covering the theory content ofmodule 1 of the subjectOnline quiz delivered through Moodle1,2Marked against a standardised answer sheetHardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 7 of 17Last modified: 25 March 2021

Assessment 3Due DateWeightingSubmissionType of CollaborationLengthDetailsStyle and formatSubject LearningOutcomesMarking CriteriaAssessment 4Due DateWeightingSubmissionType of CollaborationLengthDetailsStyle and formatSubject LearningOutcomesMarking CriteriaAssessment 5Due DateWeightingSubmissionType of CollaborationLengthDetailsStyle and formatSubject LearningOutcomesMarking CriteriaElectronic lab notebook worksheetAt the end of the prac class15%Electronic lab notebookGroup AssessmentPrac class timeRecord and analyse data collected in prac class, and answer questionspertaining to the classPractical worksheet4, 5, 6Marked against a standardised answer sheetPractical quizWeek 1210%OnlineIndividual Assessment45 minExperimental data, calculations and quiz-style questions pertaining topracticalsOnline quiz delivered through Moodle4, 5, 6Marked against a standardised answer sheetFinal theory quizDuring exam period40%Exam papers and answers must be submitted at the conclusion of theexamIndividual Assessment2 hoursMultiple choice and short answer questions covering the theory content ofmodules 2 and 3 of the subjectPaper-based final exam1, 2, 3Marked against a standardised answer sheetMinimum Requirements for a Pass in this SubjectTo receive a clear pass in this subject a total mark of 50% or more must be achieved. In addition,failure to meet any of the minimum performance requirements is grounds for awarding a TechnicalFail (TF) in the subject, even where total marks accumulated are greater than 50%.The minimum performance requirements for this subject are: achieve a combined minimum mark for the theory-related assessment tasks (2 and 5) of 45%,andachieve a combined minimum mark for the practical-related assessment tasks of 50% (1,3and 4), andmeet the minimum participation requirements set out below.Hardcopies of this document are considered uncontrolled please refer to UOW website or eLearning for the latest versionFaculty of Science Medicine and HealthPage: 8 of 17Last modified: 25 March 2021

Minimum Student Attendance and ParticipationIt is expected that students will allocate 12 hours per week to this subject, including any required classattendance, completion of prescribed readings and assessment tasks.Student attendance at practicals and tutorials is compulsory and students must attend 100% ofpractical and tutorial cl

Biochemistry (6th edition) Berg, Tymoczko & Stryer (574.192/49) Biochemistry (3rd edition) Mathews, van Holde & Ahern (574.192/88) Principles & Techniques of Biochemistry and Molecular Biology (6th edition) Wilson & Walker

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