African Americans And Clinical Research - UC Davis Health

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African Americansand Clinical ResearchIf you have ever taken a pill or been treatedfor an illness, you have seen the benefit ofclinical trials. Each year, thousands of AfricanAmericans take part in clinical trials to helpfind ways to prevent, treat, and cure illness.Clinical trials help African Americans and allpeople enjoy better health.HELPING YOU TOMAKE AN INFORMED CHOICE

What are clinical trials?Clinical trials, also known as “clinical research studies”, or “clinical studies”, arestudies in human volunteers that try to answer specific health questions. Someclinical trials measure the safety and effectiveness of potential new treatments.Other clinical trials observe health issues and behaviors in large groups ofpeople.Why are pediatric clinical studies conducted?MANY ILLNESSES such as sickle cell anemia, asthma, diabetes, heart disease, HIV/AIDS, and certain kinds of cancer, such as prostate cancer, affect African Americansmore than other people. Yet, little is known about how they respond to treatment, soAfrican American volunteers are needed to help scientists learn how differenttreatments affect them. When African Americans take part in clinical trials, they helpimprove the health of all people and provide greater understanding of healthdisparities.Clinical Trials Then and NowFOR MANY YEARS, most clinical trials were done on white men only. This meant thatgroups such as African Americans, women, and other minorities were not included.But today, clinical trials welcome the participation of all people, and those clinical trialsare closely monitored for their safe and ethical treatment of volunteers.CISCRP is not involved in recruiting patients for clinical studies, nor is it involved in conducting clinical studies.

How You Are Protected If You ParticipateSOME AFRICAN AMERICANS still remember past abuses like the TuskegeeExperiment, in which syphilis treatment was withheld from a group of AfricanAmerican men for many years. People wonder if something like that could happentoday.The answer is NO. Federal guidelines and codes of ethics are in place to protectclinical research volunteers from harm. In addition, an Institutional Review Board, apanel of professionals and community members, is responsible for monitoring studysafety and protecting volunteer rights in every clinical trial.What You Need To KnowBEFORE YOU ENROLL in a clinical trial, it is a good idea to learn as much as you canabout it. You may be interested to know that there are different kinds of clinicaltrials. Some need healthy volunteers while other clinical trials seek volunteers needingtreatment.A clinical trial is conducted according to a plancalled a protocol, which describes: What types of volunteers may enter the study The schedules of tests and procedures, studymedications and dosages Length of the study Number of study visitsBased on the requirements of the protocol, youmay or may not qualify for a specific clinical trial.If you qualify for the clinical trial, you will be askedto agree in writing to follow the protocol. This iscalled giving informed consent.

Things to Consider Before VolunteeringBEFORE TAKING PART in a clinical trial, consider the possible benefits and risks.BENEFITSThe investigational treatment studied in a clinical trial may or may not benefityou personally, but the benefits of participating are: Possibly getting treatment for an illness when no other treatment exists Receiving expert care for your condition Having early access to new treatments Knowing your participation is helping othersRISKSClinical trials study investigational treatments, therefore, some informationabout the treatments are unknown. Some risks include: Not being able to choose your treatment Receiving a treatment that may not work as planned Experiencing unpleasant or serious side effectsTo help you decide if you should participate in a clinical trial, ask questions,search the library or Internet for information (See Learn More About ClinicalTrials on back), and seek the advice of family members or a trusted doctor,clergyman or friend.Remember, your participation in clinical trials is strictlyvoluntary and you can drop out at any time for anyreason.

Questions to Ask Before Participatingin a Clinical Trial What is the purpose of this clinical trial?Why would researchers think this treatment might work for me?What are my treatment options?How will this clinical trial help my familyor my community?What will I be asked to do?How long is the clinical trial going to last?What are the possible risks?Will I have to pay for any part of the clinical trial, and will I be reimbursed forcosts of travel, parking, or meals incurred while I am in a clinical trial? If the treatment works for me, can I keep using it after the clinical trial ends? How will this study affect my daily life? Will anyone else know about my participation?

CTSC Clinical Trials Office2921 Stockton Blvd, Suite 1400Sacramento, CA 95817(855) 823-1660health.ucdavis.edu/participateThe UC Davis CTSC is a member of the national CTSA consortium andsupported by award TR001860 from the National Institutes of Health’sNational Center for Advancing Translational Sciences.CISCRP is an independent non-profit organization dedicated to engaging the public and patients aspartners in the clinical research process through education and outreach programs. CISCRP servicesalso assist clinical research stakeholders in understanding public and patient attitudes & experiencesin research to improve patient satisfaction. CISCRP is not involved in recruiting patients for clinicaltrials, nor is it involved in conducting clinical trials.One Liberty Square Suite 510 Boston, MA 02109Visit www.CISCRP.org or Call toll free 1-877-633-4376 2018 CISCRP All Rights Reserved. No part of this document may be reproduced without written consent from CISCRP.

African Americans and Clinical Research If you have ever taken a pill or been treated for an illness, you have seen the benefit of clinical trials. Each year, thousands of African Americans take part in clinical trials to help find ways to prevent, treat, and cure illness. Clinical trials help African Americans and all people enjoy better health.

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