Cancer Institute - MCQ
قسم باثولوجيا األورام معهد جنوب مصر لألورام South Egypt Cancer Institute – MCQSelect the best single answer:1- Hyperplasia is characterized by all of the following except:a- the hormonal type is the commonest exampleb- sometimes precancerousc- always irreversibled- may lead to organ hyperfunctione- monotony of hyperplastic cells2- Atrophy is characterized by all of the following except:a- decrease in size and number of cellsb- common in brain of old agec- may be congenitald- may result from a disuse of an organ3- Hypertrophy is:a- associated with increased cell numberb- rare in the heartc- often predispose to malignancyd- all of the abovee- non of the above4- Hypertrophy is characterized by all of the following except:a- not always pathologicalb- usually results in an increase of the blood supply of the tissuec- common in the heartd- precancerouse- may be associated with hyperplasia5- Hyperchromatism is seen in:a- degenerated cellsc- signet-ring cellsb- necrotic cellsd- dysplastic cells6- Squamous metaplasia may result from:a- bilharziasisb- smokingc- bothd- neither
7- Metaplasia is:a- common in the skinc- bothb- only seen in epithelial tissuesd- neither8- As a physician, you should be concerned about a surgicalpathology report that describes metaplasia in a biopsy because:a- this change indicates irreversible tissue damageb- it may be due to irritant that can be avoidedc- the patient will probably develop cancerd- It may be due to viral infection that can be treatede- Any of the above9- Hyperplastic tissues:a- show marked cellular pleomorphismb- may become neoplasticc- are always irreversible lesionsd- all of the abovee- non of the above10-A paraplegic patient aged 30 yrs., he is expected to have:a- atrophy of the calf musclesb- hypertrophy of the calf musclesc- bothd- neither11- Neoplasia is characterized by:a- has no stimulusc- not coordinatede- non of the aboveb- has no useful functiond- all of the above12- All these benign tumours are capsulated except:a- lipomab- chondromac- angiomad- neurofibromae- fibroadenoma13- Malignant tumour of mesenchymal tissues is called:a- adenocarcinomab- sarcomac- mucoid carcinomad- squamous cellcarcinoma
14- A malignant ulcer is characterized by:a- necrotic floorc- indurated basee- non of the aboveb- raized everted edged- all of the above15- The edge of a malignant ulcer is:a- underminedc- punched oute- slopingb- rolled overd- everted16- Precancerous lesions include:a- papilloma of the tonguethyroidc- bilharziasis of the urinary bladdere- non of the above17-The nuclei of malignant cells show:a- variability in sizec- variability in shapee- all of the aboveb- adenoma of thed- all of the aboveb- hyperchromatismd- abnormal mitosis18- Transcoelomic spread occurs in carcinoma of:a- breastb- tonguec- skind- stomache- non of the above19- Squamous cell carcinoma occurs as a primary tumour in thefollowing sites except:a- skinb- gall bladderc- urinary bladderd- tonguee- liver20- The following tumours give distant metastasis except:a- basal cell carcinomab- squamous cellcarcinomac- adenocarcinomad- scirrhous carcinomae- encephaloid carcinoma21- Which of the following is not a benign tumour:a- adenomab- fibromac- chondromad- papillomae- haematoma
22- Osteoclastoma is:a- benign tumour of bonebonec- locally malignant tumour of boned- metastatic tumour of bone23- A benign tumour usually shows:a- lymphatic spreadc- many mitotic figurespopulatione- extensive necrosisb- malignant tunour ofe- non of the aboveb- blood spreadd- mature cell24- Neoplasia means:a- disturbance in cellular growthb- disturbance in cellular differentiationc- disturbance in both cellular growth and differentiatione- all of the above25- The most common malignant tumour of the liver:a- cholangiocarcinomab- hepatocellularcarcinomac- metastatic carcinomad- sarcoma26- Carcinoma in situ is:a- carcinoma of unknown originc- carcinoma with bad prognosiscarcinomae- carcinoma occurs in certain sites.b- occult carcinomad- non invasive27- Locally malignant tumours include all except:a-adamantinomab- osteoclastomac- basal cell carcinomad- mixed salivary glandtumoure- osteosarcoma28- All tumours metastasizing in bone result in bone destructionexcept:a- thyroid gland carcinomab- breast carcinomac- prostatic carcinomad- renal cell carcinomae- bronchogenic carcinoma
29- An occult carcinoma is:a- in situ carcinomab- locally malignant carcinomac- clinically undetectable primary carcinoma, manifested by metastasisd- all of the abovee- none of the above30- A male patient aged 63 years with multiple osteolytic lesions inthe skull, he is expected to have:a- osteomalaciab- miliary tuberculosisc- prostatic carcinomad- melanomae- none of the above31- Basal cell carcinoma spreads by:a- transcoelomicc- lymphe- non of the above32- Osteoclastoma is:a- benign tumour of bonec- locally malignat tumour of bonebonee- none of the above33- A locally malignant tumour includes:a- bronchial adenomac- adamantinomae- all of the above34- A benign tumour usually shows:a- stromal invasionpopulationc- lymphatic spreade- extensive necrosis35- Teratoma areise from:a- multipotent cellsc- totipotent cellse- none of the aboveb- bloodd- all of the aboveb- malignant tumour of boned- metastatic tumour ofb- rodent ulcerd- desmoid tumourb- mature celld- many mitotic figuresb- unipotent cellsd- all of the above36- The following tumours give distant metastasis except:a- squamous cell carcinomab- basal cell carcinomac- adenocarcinomad- scirrhous carcinomae- encephaloid carcinoma
37- Krukenberg tumour:a- primary tumour of the ovaryb- associated withhydrothoraxc- secondary tumour reach the ovary by the blood streamd- secondary tumour that reach the ovary by transcoelomic spreade- all of the above38- Krukenberg tumour:a- usually bilateral ovarian tumourb- associated withmalignant ascitisc- secondary tumour that reach the ovary by transcoelomic spreadd- reach the ovaries from the GITe- all of the above39- The following are examples of hereditary cancer except:a- breast carcinomab- colon carcinomac- Wilm's tumourd- osteogenic carcinomae- retinoblastoma40- Viruses that have been associated with malignancy include all ofthe following except:a- rhinovirusb- hepatitis B virusc- human immunodeficiencyd- human papilloma viruse- human T-lymphocyte virus, type I41- Tumour cachexia is related to all except:a- depression leading to anorexiasensationc- tumour necrosis factore-None of the aboveb- altered tasted- altered deglutition42- 1-Hyperplasia is characterized by all of the following except:a-the hormonal type is the commonest exampleb-sometimes precancerousc-always irreversibled-may lead to organ hyperfunctione-monotony of hyperplastic cells43- Hypertrophy is:a-associated with increased cell numberb-rare in the heart
c-often predispose to malignanyd-all of the abovee- non of the above44- As a physician, you should be concerned about a surgicalpathology report that describes metaplasia in a biopsybecause:a-this change indicates irreversible tissue damageb-it may be due to irritant that can be avoidedc-the patient will probably develop cancerd-It may be due to viral infection that can be treatede-any of the above45- Neoplasia is characterized by:a- has no stimulusb- has no usefulfunctionc- not coordinatedd- all of the abovee- non of the above46- All these benign tumours are capsulated except:a- lipomab- chondromac- angiomad- neurofibromae- fibroadenoma47- The edge of a malignant ulcer is:a- underminedc- punched oute- sloping48- Precancerous lesions include:a- papilloma of the tonguethyroidc- bilharziasis of the urinary bladdere- non of the above49- A benign tumour usually shows:a- lymphatic spreadc- many mitotic figurespopulatione- extensive necrosisb- rolled overd- evertedb- adenoma of thed- all of the aboveb- blood spreadd- mature cell
50- Carcinoma in situ is:a- carcinoma of unknown originc- carcinoma with bad prognosiscarcinomae- carcinoma occurs in certain sites.51- Teratoma areise from:a- multipotent cellsc- totipotent cellse- non of the aboveb- occult carcinomad- non invasiveb- unipotent cellsd- all of the above52- A male patient aged 63 years with multiple osteolytic lesions inthe skull, he is expected to have:a- osteomalaciab- miliary tuberculosisc- prostatic carcinomad- melanomae- non of the above53- The following are examples of hereditary cancer except:a- breast carcinomab- colon carcinomac- Wilm's tumourd- osteogenic carcinomae- retinoblastoma54- Anaplastic tumour is a tumour in which the tissue is:a- well differentiatedb- moderatelydifferentiatedc- poorly differentiatedd- undifferentiated55- Krukenberg tumour is:a- primary tumour of the ovaryb- associated withhydrothoraxc- secondary tumour reach the ovary by the blood streamd- secondary tumour that reach the ovary by transcoelomic spreade- all of the above56- The most common malignant tumour of the liver:a- cholangiocarcinomab- hepatocellularcarcinomac- metastatic carcinomad- sarcoma57- Viruses that have been associated with malignancy include all ofthe following except:a- rhinovirusb- hepatitis B virusc- human immunodeficiency virusd- human papilloma virus
e- human T-lymphocyte virus, type I58- Tumour cachexia is related to all except:a- depression leading to anorexiab- altered taste sensationc- tumour necrosis factord- altered deglutitione- non of the above59- As a physician, you should be concerned about a surgicalpathology report that describes metaplasia in a biopsy because:a-this change indicates irreversible tissue damageb-it may be due to irritant that can be avoidedc-the patient will probably develop cancerd-It may be due to viral infection that can be treated60- All are true for gatekeeper genes except:1- maintain the integrity of the genome by repairing DNA damage2- inhibit the proliferation, or promote the death of cells withdamaged DNA3- are exemplified by the p35 gene4- are mutated in familial neuroblastoma5- are exemplified by the BRCA1 gene61- Telomeresa- are situated in the centromeric regions of chromosomesb- lengthen with each cell divisionc- are non-coding tandemly repetitive sequences of DNAd- are replicated by the enzyme telomerasee- are prematurely shortened in progeria62- Ionizing radiationA- increases DNA synthesisB- increases H2O2 in the tissuesC- breaks disulphide bondsD- causes atrophy of the seminiferous tubules of the testis63- Viruses that have been associated with malignancy include allof the following except:a- rhinovirusb- hepatitis B virusc- human immunodeficiencyd- human papillomavirusf- human T-lymphocyte virus, type I
64- Tumour cachexia is related to all except:a- depression leading to anorexiasensationc- tumour necrosis factore- non of the aboveb- altered tasted- altered deglutition65- As a physician, you should be concerned about a surgicalpathology report that describes metaplasia in a biopsy because:a-this change indicates irreversible tissue damageb-it may be due to irritant that can be avoidedc-the patient will probably develop cancerd-It may be due to viral infection that can be treatede-any of the above66-A male patient aged 63 years with multiple osteolytic lesions in theskull, he is expected to have:a- osteomalaciab- miliary tuberculosisc- prostatic carcinomad- melanomae- non of the above67- Fourth event in this series?Abudding of C-type particle from cell surfaceBreplicationCRNA virus enters cellDSynthesis of DNA provirusESynthesis of reverse transcriptase68- Tetraploidy in a tumour can only be recognized with certainly bya chromosome count on a dividing cell, but the next best indicatoris a nucleus that?A- contains four times the normal amount of DNAB- contains twice the normal amount of DNAC- has two nucleoliD- is four times the normal diameterE- is twice the normal diameter69- All are true for cellular proto-oncogenes except:A- may be converted to cellular oncogenes by placement next topromoter genesB- are responsible for the production of cellular constituents ofenzymes
C- the cellular proto-oncogenes responsible for chronic myeloidleukemia is the same as that for Burkitt's lymphomaD- contain similar genetic structures to viral oncogenesE- may be converted into cellular oncogenes by gene amplification70- Atrophy is characterized by all of the following except:a-decrease in size and number of cellsb-common in brain of old agec-may be congenitald-may result from a disuse of an organ71- Hypertrophy is characterized by all of the following except:a-not always pathologicalb-usually results in an increase of the blood supply of the tissuec-common in the heartd-precancerouse-may be associated with hyperplasia72- Squamous metaplasia may result from:a- bilharziasisc- bothb- smokingd- neither73- Hyperplastic tissues:a-show marked cellular pleomorphismb-may become neoplasticc-are always irreversible lesionsd-all of the abovee-non of the above74- A malignant ulcer is characterized by:a- necrotic floorb- raized everted edgec- indurated based- all of the abovee- non of the above75- The nuclei of malignant cells show:a- variability in sizec- variability in shapee- all of the aboveb- hyperchromatismd- abnormal mitosis176- The following tumours give distant metastasis except:a- basal cell carcinomab- squamous cell carcinomac- adenocarcinomad- scirrhous carcinoma
e- encephaloid carcinoma77- Krukenberg tumour:a- usually bilateral ovarian tumourb- associated withmalignant ascitisc- secondary tumour that reach the ovary by transcoelomic spreadd- reach the ovaries from the GITe- all of the above78- Viruses that have been associated with malignancy include all ofthe following except:a- rhinovirusb- hepatitis B virusc- human immunodeficiencyd- human papillomaviruse- human T-lymphocyte virus, type I79- Tumour cachexia is related to all except:a- depression leading to anorexiab- altered taste sensationc- tumour necrosis factord- altered deglutitione- non of the above80- Osteoclastoma is:a- benign tumour of boneof bonec- locally malignant tumour of boned- metastatic tumour of boneb- malignant tunoure- non of the above81- Neoplasia means:a- disturbance in cellular growthb- disturbance in cellular differentiationc- disturbance in both cellular growth and differentiatione- non of the above82- Locally malignant tumours include all except:a- adamantinomab- osteoclastomac- basal cell carcinomad- mixed salivary glandtumoure- osteosarcoma83- An occult carcinoma is:a- in situ carcinomacarcinomab- locally malignant
c- clinically undetectable primary carcinoma, manifested bymetastasisd- all of the abovee- non of the above84- NOT true of retinoblastoma:A- Cells small, often arranged in rosettes1- Five year survival under 15%2- Occurs in infants3- Often bilateral4- Often familial85- Lymphoma of the stomach:a- may be primary or secondary in the stomachb- has a better prognosis than carcinoma of the stomachc- bothd- neither86- The most biologically aggressive pigmented skin lesion is:a- junction nevusb- compound nevusc- Intradermal nevusd- Blue nevuse- Lentigo maligna87- NOT true of giant cell tumours of bone (osteoclastoma)1- about 20% metastasize2- are surrounded by a zone of dense new bone3- Haemorrhage and haemosidrin-laden phagocytes common4- Histologically a mixture of spindle cell and multinucleated giantcells5- Occurs chiefly at bone ends, especially at knee88- Which one of the following is the commonest neoplastic cause ofenlargement of lymph nodea-chronic lymphatic leukaemiab-diffuse non-Hodgkin's lymphomac-follicular lymphomad-nodular sclerosis Hodgkin's lymphomae-secondary carcinoma89- Viruses that have been associated with malignancy include all ofthe following except:a- rhinovirusb- hepatitis B virusc- human immunodeficiency virusd- human papilloma virus
e- human T-lymphocyte virus, type I90- Tumour cachexia is related to all except:a- depression leading to anorexiab- altered taste sensationc- tumour necrosis factord- altered deglutitione- non of the above91- All these benign tumours are capsulated except:a- lipomab- chondromac- angiomad- neurofibromaf- fibroadenoma92- As a physician, you should be concerned about a surgicalpathology report that describes metaplasia in a biopsy because:a-this change indicates irreversible tissue damageb-it may be due to irritant that can be avoidedc-the patient will probably develop cancerd-It may be due to viral infection that can be treatede- any of the above93- Neoplasia means:a- disturbance in cellular growthb- disturbance in cellular differentiationc- disturbance in both cellular growth and differentiatione- non of the above94- An occult carcinoma is:a- in situ carcinomab- locally malignantcarcinomac- clinically undetectable primary carcinoma, manifested bymetastasisd- all of the abovee- non of the above95- Krukenberg tumour:a- usually bilateral ovarian tumourb- associated withmalignant ascitisc- secondary tumour that reach the ovary by transcoelomic spreadd- reach the ovaries from the GITe- all of the above96- The following are examples of hereditary cancer except:a- breast carcinomab- colon carcinomac- Wilm's tumourd- osteogenic carcinoma
97- Hereditary predisposition to the development of tumours occursin the following sites:a- Retinab- Colonc- Uterusd- Skine- Stomach
Select the best single answer:1. During a routine physical examination, a 49-year-old man isfound to have a 2.5-cm “coin lesion” in the upper lobe of his leftlung. The lesion is removed surgically, and histologic sectionsreveal sheets of malignant cells with clear cytoplasm (clear cellcarcinoma). Which of the following is the most likely site of originfor this metastatic lung tumor?a. Appendixb. Breastc. Kidneyd. Pancrease. Stomach2. A 17-year-old man presents with a lesion on his face that measuresapproximately 1.5 cm in its greatest dimension. He has a history ofnumerous similar skin lesions that have occurred mainly in sunexposed areas. The present lesion is biopsied and reveals aninvasive squamous cell carcinoma. This patient most probably hasone type of a group of inherited diseases associated with unstableDNA and increased incidence of carcinoma. Which of thefollowing is the most likely diagnosis?a. Xeroderma pigmentosab. Wiskott-Aldrich syndromec. Familial polyposisd. Sturge-Weber syndromee. Multiple endocrine neoplasia type I3. A 57-year-old man presents with signs of fatigue that are theresult of anemia. Workup reveals that his anemia is the result ofbleeding from a colon cancer located in the sigmoid colon. Thelesion is resected and at the time of surgery no metastatic diseaseis found. Which of the following markers would be most useful forfuture follow-up of this patient for the evaluation of possiblemetastatic disease from his colon cancer?a. alpha fetoprotein (AFP)b. Carcinoembryonic antigen (CEA)c. Chloroacetate esterase (CAE)d. Human chorionic gonadotropin (hCG)4. A 14-month-old male infant presents with an enlarging abdominalmass. Laboratory examination reveals increased urinary levels ofmetanephrine and vanillyl mandelic acid (VMA). A histologicsection from the mass reveals a tumor composed of small,primitive-appearing cells with hyperchromatic nuclei and little to
no cytoplasm. Occasional focal groups of tumor cells are arrangedin a ring around a central space. Which of the following is themost likely diagnosis?a. Adrenal cortical carcinomab. Ganglioneuromac. Nephroblastomad. Neuroblastomae. Pheochromocytoma5. A 35-year-old man living in a southern region of Africa presentswith increasing abdominal pain and jaundice. He has worked as afarmer for many years, and sometimes his grain has becomemoldy. Physical examination reveals a large mass involving theright side of his liver, and a biopsy specimen from this massconfirms the diagnosis of liver cancer (hepatocellular carcinoma).Which of the following substances is most closely associated withthe pathogenesis of this tumor?a. Aflatoxin B1b. Direct-acting alkylating agentsc. Vinyl chlorided. Azo dyese. Naphthylamine6. A 59-year-old man is found to have a 3
pathology report that describes metaplasia in a biopsy because: a-this change indicates irreversible tissue damage b-it may be due to irritant that can be avoided c-the patient will probably develop cancer d-It may be due to viral infection that can be treated e-any of the above 66-A male patient aged 63 years with multiple osteolytic lesions .
Ovarian cancer is the seventh most common cancer among women. There are three types of ovarian cancer: epithelial ovarian cancer, germ cell cancer, and stromal cell cancer. Equally rare, stromal cell cancer starts in the cells that produce female hormones and hold the ovarian tissues together. Familial breast-ovarian cancer
Sample MCQ’s for Nutrition and Meal Planning (20 - 21 batch only) Subject: Nutrition and Meal Planning Semester: III Class: SYBSc Instructions: 1. Attempt any 8 MCQ’s out of 10. 2. Each MCQ carries 1.5 marks 3. Read each statement carefully and mark any one option out of the four Options that you think is the correct answer 4.
AUTHORISATION TO TAKE Australian Medical Council MCQ EXAMINATION WITH PEARSON VUE You have been authorised to take a MCQ examination at a Pearson VUE testing center. Information on the MCQ Examination, the testing rules, and how to schedule your MCQ Examination follows: Awarding Body: Australian
MCQ 11.74 When sampling is done with or without replacement, is equal to: MCQ 11.75 If X represent the number of units having the specified characteristic and n is the size of the sample, then popula
As the Chair and Co-Chair of the Kansas Cancer Partnership (KCP), we are pleased to provide . you with the 2017-2021 Kansas Cancer Prevention and Control Plan. This plan is the result of . Breast Biopsies Breast Cancer Cervical Cancer Colorectal Cancer Lung Cancer Prostate Cancer. Post-Diagnosis & Quality of Life throughout the Cancer Journey.
cancer, pancreatic cancer, breast cancer, lung cancer, liver cancer, kidney cancer, brain cancer & brian tumors, lymphoma, blood diseases, bone cancer & all types of viruses Used externally as a skin cancer treatment, treating carcinoma, melanoma, warts, moles & as a drawing salve People with in-operable cancers sent home to die have used black
Tier 3: Florida-based cancer centers in pursuit of designation as either a NCI-designated Cancer Center or NCI-designated Comprehensive Cancer Center Currently, there are three participating cancer centers: H. Lee Moffitt Cancer Center, University of Florida Shands Cancer Hospital, and University of Miami Sylvester Comprehensive Cancer Center.
What does skin cancer look like? There are many different types of skin cancer (such as melanoma and basal cell skin cancer). Each type looks different. Also, skin cancer in people with dark skin often looks different from skin cancer in people with fair skin. A change on the skin is the most common sign of skin cancer. This may
