Ventilation For Infection & Comfort Control In Hospital .

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Ventilation for Infection & ComfortControl in Hospital Operating RoomsPresented by: Brian Sikorski P.Eng.E-Factor Engineering, IncorporatedCHES BC, KelownaMarch 28th 2006Photo fromhttp://www.precisionairproducts.com/

Presentation OverviewThe Role of Ventilation in Operating RoomsDesign Guidelines and Standards Review andComparisonAir Filtration – To HEPA or not to HEPA?Air Change Requirements for the ORAir Diffusion System DesignTemperature and Humidity ControlAir Handling SystemsEnergy Conservation Ideas

Buzzwords and AcronymsAIA – American Institute of ArchitectsASHE – American Society of Healthcare EngineeringASHRAE – American Society of Heating, Refrigeration, and AirConditioning EngineersCDC – Center for Disease ControlCHES – Canadian Health Engineering SocietyHICPAC - Healthcare Infection Control Practices AdvisoryCommitteeAII - Airborne Infection Isolation (negative)OR – Operating Room (positive)PE – Protective Environment (positive)

The Infection ProblemASHRAE – Working to Ensure Healthcare Facilities Remain Healthy, a report by Ronald Vallort,Past President ASHRAE, Inc. 2005 from Business Briefing: Hospital Engineering & Facil. Mgmt.ASHRAE HVAC Design Manual for Hospitals and Clinics Appendix D

Surgical Site Infection (SSI) The Surgical Site - the area of the wound subject toinfectionSources of Infection – mainly from skin cells shedfrom exposed regions of skin, both from operatingroom staff and the patient.1 (Up to 30,000 deadcells/hour can fall from a surgeon’s face)2These skin cells or squames particles are around 10 µmin diameter.A unit of bacteria contaminated squames is a cfuNot likely to infect but possible.“Many SSI cases are caused by airborne exogenousorganisms”3See endnotes on last slide for references

Protection of Surgical SiteProtect the Surgical Site from Infection byproviding:Proper Clothing worn by OR occupantsAntibiotic Treatment of the WoundSterilized InstrumentsEffective Ventilation to Dilute and RemoveContaminants

The Ventilation Solution"Evidence from many studies leaves no doubt that hospital airquality and ventilation play decisive roles in affecting airconcentrations of pathogens.and, in this way, have major effects on(reducing) infection rates"Report to The Center for Health Design for the "Designing the 21st CenturyHospital Project". This project is funded by the Robert Wood Johnson Foundation.September 2004.

Standards and Guidelines“At this point in time, there is nointernationally agreed standard for airquality in hospitals and healthcarefacilities”11.Excerpt from “An Update on Proposed ASHRAE Standard”, Frank .A. Mills BSc, CEngpresented at Seminar “Hospital Infection Control”, London, 13 June 2005

Design Standards & Guidelines forOR Ventilation ASHRAE Standards and Guidelines CSA Standards Z317.2-01 Special Requirements for Heating, Ventilation , andAir Conditioning in Health Care FacilitiesAmerican Institute of Architects: Standard 52.1 1992 and 52.2 1999: laboratory methods fortesting air filter performance2003 Handbook HVAC Applications Ch. 7 - Health CareFacilitiesHVAC Design Manual for Hospitals and Clinics (2003)Standard 170p Ventilation of Healthcare FacilitiesASHRAE/ASHE (expect – Spring 2006)Guidelines for Design and Construction of Hospital and HealthCare Facilities: 2001 Edition (wait for 2006 edition)BC Building Code – Part 9 References to CSA Z317 and ASHRAE HVACHandbook

ASHRAE Standard 52.2 Filters andMERV Standard 52.2 – 1999: Method of Testing GeneralVentilation Air Cleaning Devices for RemovalEfficiency by Particle SizeStd develops the MERV (Minimum EfficiencyReporting Value) filter's performance is determined by comparing airborneparticle counts upstream and downstream of the air filterMERV’s are accompanied by a resistance to air flowmeasurement (pressure drop)MERV’s number 1 to 20 with highest being most efficient

ASHRAE Standard 52.2 Test ResultsTypeDisposable Panel Filters,Fiberglass &Synthetic Filters,Permanent SelfCleaning Filters,ElectrostaticFilters, WashableMetal Foam FiltersMERV Std. 52.21-4TypicalAir FilterPleated Filters,Non-SupportedBag Filters,Non-SupportedBag Filters,HEPA Filters,Extended Surface Filters,Rigid Box Filters,Rigid Box Filters,ULPA Filters,Media Panel Filters5-8Rigid Cell /CartridgeFilters9-12Rigid Cell /CartridgeFilters13-16DOP forHEPA/ULPASULPA Filters17-2099.97% to 100%Average Dust-SpotEfficiency 20 % 20 to 35%40 to 75%80 to 95% Average ArrestanceASHRAE Std.52.160 to 80%80 to 95% 95 to 98%98 to 99%N/AParticle SizeRanges 10.0 µm3.0-10.0 µm1.0-3.0 µm0.30-1.0 µm 0.30 µmResidential,Industrial Workplace,IndustrialWorkplace,Smoke Removal,Clean Rooms,Light Commercial,Commercial,High EndCommercialBuildingsGeneral Surgery,High Risk Surgery,Equipment ProtectionPaint BoothsTypical Air FilterApplicationsHospitals andHealth erials

Air Filtration – HEPA Filters HEPA – High Efficiency Particulate Air filters Originally developed in the 1940’s by AEC to filter outradioactive particlesThe filter shall exhibit a minimum efficiency of 99.97%when tested at an aerosol of 0.3 µm (micrometers)diameter (DOP)Pressure drop shall be about 1.0 in wc @ 1000 cfm for24” x 24” x 11 ½” (DOE-STD-3020-97)

HEPA Filter Performance

Proposed ASHRAE Standard 170pStandard 170P, Ventilation of Health Care FacilitiesTo be released June 2006Based on Existing ASHRAE recommendations, HVACDesign Manual, AIA Guidelines, and extensive pier andmember review.Intent to limit potential for infection transfer viaventilation pathsSpecifies ventilation design for Operating Rooms

ASHRAE/ASHE Standard 170p OR’s will be placed in 3 classifications1:Class A: least stringent – local anesthesia, includesmost clinics and medical office buildings used forminor surgery Class B: single or multi-specialty facilities wheresedation anesthesia or dissociative drugs areadministered Class C: most stringent - single or multi-specialtyfacilities administering general anesthesia 1. Based on the “Guidelines for Optimal Ambulatory Surgical Care and Office Based Surgery”(American College of Surgeons 2000)

ASHRAE Standard 170p Minimum outside air change rate to be 4 ACH and total to 20ACHAir Filtration Pressure Maintain at positive pressure wrt. adjoining spaces 2.5 Pa (0.01 inw.g.)Proposed temperature and humidity conditions for general OR to be filtered 1st to MERV 8 and 2nd to MERV 14, largeorgan transplant and orthopedic surgery to MERV 17 (HEPA) in 2ndbankRoom 68 F to 75 F (20 C to 23.8 C)RH range from 30% to 60%Minimum requirement for type and location of diffusers Probably Laminar Flow Ceiling Grilles – Group E downflow, lowentrainment of room airReturn Air Grilles are proposed to be low side wall not less than 150 mm(6 in.) above the floor

ASHRAE Std 170p Air Diffusers “Shall” be: Centered in the room over the surgical tableMust extend 12”-18” (300 to 450 mm) beyond tablefootprint (with allowance for other stuff in ceiling e.g.lighting anchors, gas columns for outlets“Shall” have: Face velocity shall be between 25 and 35 fpm (0.125m/sec – 0.18 m/sec)

CSA Z317.2-01 Special Requirementsfor HVAC Systems in Health Care Three Area Classifications I II and III. Class Iincludes Patient Care areas with “Risk” to thepatient – Including Operating Rooms (verygeneral)Three Classes of Facilities A, B, and C. Class Ahas surgical operating rooms

CSA Z317.2-01 Special Requirementsfor HVAC Systems in Health CareFor Operating Rooms Minimum outside air change rate to be 6 ACH and total to 20 ACH Air FiltrationSpecialized Operating Rooms shall be 99.97 % Efficient (HEPA)Pressure 6.11.2 specifies that: Proposed temperature and humidity conditions Differential between areas shall be greater than 0.762 mm of water pressure (7.5 Pa, 0.03 inwc) (3 times ASHRAE 170p)Room 17 C to 27 CRH range from 45% to 55%Minimum requirement for type and location of diffusers 6.12.3.2 specifies that:Air supply for operating rooms, delivery rooms shall be through nonaspirating ceilingoutlets near the center of the work area

CSA and HEPA Filters for OR’s CSA Z317.2-01 Article 6.8.4 states:Where present, HEPA filters in the supply air systemsshall bea)b)c)d)Located at the point where the air enters the roomProvided with test ports before and after the filter, andtested Designed to permit removal, disposal, and replacementwithout introducing contamination of the area servedProvided with means to indicate pressure drop to a BMS ora local alarm to indicate pressure drop

Guideline Comparisons for ACH and FiltrationCompliments of AJ Manufacturing HOSPITAL/CLEAN ROOM DIFFUSERS, Rob Haake

Air Change Rate DiscussionSimple Definition ACH CFM x 60/Room Volume (ft3) This is the Total Air Change Rate in a room The outdoor air portion creates the air change,removes odours, chemicals, and gases Recirculated air is OK to remove particles Comment: In North America it is standard practice to recirculate airwhile in the UK it is not allowed. Who is right?

Some Air Change TheoryContaminant Decay Rate at 1 ACH10.9C (t ) e ACH tUnit Concentration0.80.70.60.5Reaches 63.2% after 1 time constant0.40.30.2Reaches 95% after 3 time constants0.100.0001.0002.0003.000Time (Hours)4.0005.0006.000

Air Change Rate Effects onContaminantsOutdoor Air Change Rate vs Time to Purge Space1200.0CO2@4 ACHCO2@10 ACHCO2@15 ACH1000.0Concentration (PPM)ACH 000.800Time (hour)1.0001.2001.400

Air Change Rate Review Standards/Guidelines cite minimum ACH ratesStudies show extreme rates do not help(Memarzadeh)It takes 5 ACHOA time constants to clear 99% ofa contaminant released quickly into a roomAir Change effectiveness depends on the roomdesign, diffuser locations, ceiling heights androom size.

Comparison of Effectiveness of ACH andDiffuser Type PerformanceFrom “Comparison of Operating Room Ventilation Systems in the Protection of the Surgical Site”,Farhad Memarzadeh, P.E., Ph.D. Andrew P. Manning, Ph.D. ASHRAE Transactions Research 2002

Air Diffuser Options Laminar Perforated DiffusersLaminar Diffuser With Terminal HEPA FilterPrecision Air Products: Laminar diffuser

Good (and Bad) Ventilation Design“Operating Room Ventilation – Why and How – Some Drawbacks Suggestions – and Economy” Sven Friberg, Babro Friberg UMEA Sweden

Air Diffuser Array Design Complete Laminar Grid (Kelowna Hospital)Produce a lowvelocity airflow, nonaspirating,vertical airpattern.Air isexhaustedevenly fromlow wall airgrills.

Air Diffuser Array Design Laminar Grid with Perimeter Air Curtain (AJ Manufacturing)

Air Diffuser Array DesignVancouver General Hospital: JP North OR9 Laminar Core with Perimeter AirCurtain

Air Distribution Performance

Air Handling System Options VAV/CAV System with Terminal ReheatDual Duct System with Mixing Boxes

Heat Recovery Options Runaround Loop - Simpleand Cost Effective, good forretrofit (50% eff.)Heat Pipe – good if exhaustvery near supply (60% eff.or more)Fixed Plate HeatExchangers (60% to 80%)Enthalpy Wheel – Up to80% total recovery. Notallowed for OR’s or AII’sRunaround Loop Heat Recovery

Temperature and Humidity Control Temperature Control Winter Humidity Control Use good sensors, calibrate regularly (annual)Allow setpoint control only between values of 19 C to 22 C ifpossible, unless OR has special requirementsOnly use spray humidifiers from plant steam or Steam toSteam injection. Do not leave stagnant water.Humidifiers should not be placed directly over the OR toavoid water leaksAllow a long enough length of duct downstream to absorb allwater – no carry over allowedGet expensive RH sensors – reliable, accurate, lowmaintenance. Vaisala are best but 400 ea.Tuning of Controllers Air flow, temperature, and humidity need to be steady.

Special Temperature Conditions In Cardiac Surgery, some surgeons requiretemperatures to be rapidly lowered to 16 C and thenrapidly heated to 26 CIn solid organ transplant rooms, rooms need to bequickly lowered to 18 C or lower. With rooms underhigh loading, this may require sub-cooling of the air to7.5 C

Energy Conservation Keep reheat to minimumMonitor OR temperatures and reset AHU SATInstall VFD on Supply/Return/Exhaust Fanand reset duct pressures (for VAV)Install Heat Recovery – for systems with 100%OA if economicalReduce Ventilation Rate when unoccupied to40% or lower if pressure control maintained.Use low resistance air filters

VGH Operating Room Systems 24 OR’s in VGH main surgical suite4 are dedicated to emergency surgeryAll are 100% outdoor air around 20 ACHNewer OR’s are served by VAV system w TerminalReheat and Heat Recovery (runaround loop).Older OR’s in Jim Pattison North are Dual Duct w/oheat recovery – air flow is reduced after hoursTour via BMS and Photos

Summary of Main Points Ventilation in Operating Rooms is for control of SSI.The main culprits for infection are squames shed by occupants.Many guidelines exist for Air Quality in Health Care but CSAZ317.2-01 and ASHRAE 170p focus on OR VentilationHEPA filters are required for orthopedic, large organ transplant,surgery and should be at the diffuser.Rectangular Arrays of Laminar Diffusers without air curtain arepreferred design for high risk surgery areas.Humidity control needs expensive sensors, regular calibration,and no potentially stagnant sources.Allow a range of temperature control but do not defeat the SSIneeds.Energy Conservation is desirable, but room pressure andinfection control must be maintained.

End Notes 1. Comparison of Operating Room Ventilation Systemsin the Protection of the Surgical Site, FarhadMemarzadeh, P.E., Ph.D. (from ASHRAE HVACDesign Manual for Hospitals and Clinics)2. Excerpt from “An Update on Proposed ASHRAEStandard”, Frank A. Mills BSc, CEng presented atSeminar “Hospital infection control”, London, 13 June20053. From Research Considered on OR Air; ASHRAEInsights, December 7th 2004)

The Ventilation Solution "Evidence from many studies leaves no doubt that hospital air quality and ventilation play decisive roles in affecting air concentrations of pathogens.and, in this way, have major effects on (reducing) infection rates" Report to The Center for Health Design for the "Designing the 21st Century Hospital Project".

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