Course Scheme & Syllabi For M.Sc. (Hons . - DAV University

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DAV UNIVERSITY, JALANDHARD AV UNIVERSITY JALANDHARCourse Scheme & SyllabiForM.Sc. (Hons.) ZOOLOGY(Program ID-37)1st to 4th SEMESTERSyllabi Applicable for Admissions in 2018Page 1 of 63

DAV UNIVERSITY, JALANDHARSCHEME OF COURSESM.Sc. (Hons.) ZoologySemester 1S. No.1PaperCodeCourse TypeZOO530CoreCourse TitleAnimal Physiology- ILTPCr410440042ZOO531Core3ZOO532CoreMolecular Biology4004CoreCell and Molecular BiologyLaboratory00324ZOO533Cell ogy Laboratory00327BCH524CorePrinciples of Biochemistry4004CorePrinciples of BiochemistryLaboratory00328BCH525TotalL: LecturesT: TutorialsP: PracticalsCr: CreditsPage 2 of 6326

DAV UNIVERSITY, JALANDHARSCHEME OF COURSESM.Sc. (Hons.) ZoologySemester 2S. No.123PaperCodeCourse TypeZOO536ZOO537ZOO5384Course TitleLTPCrAnimal Physiology- II4104Animal PhysiologyLaboratoryAdvanced Techniques inZoology00324004Advanced Techniques inZoology Laboratory0032CoreBiosystematics4104CoreEcology and ConservationBiology4004Ecology and ConservationBiology 7CoreZOO5428Open Elective Course ITotalL: LecturesT: TutorialsP: PracticalsCr: CreditsPage 3 of 63426

DAV UNIVERSITY, JALANDHARSCHEME OF COURSESM.Sc. (Hons.) ZoologySemester 3S. No.PaperCodeCourse TypeCourse 47LTPCrGenetics4004CoreGenetics Laboratory0032CoreDevelopmental Biology4004CoreDevelopmental BiologyLaboratory0032CoreProject –I *2002Seminar-I*6Open Elective Course II47Departmental Elective I6Departmental Elective I (Choose any one theory)ZOO6641ZOO665ZOO6662ElectiveAnimal Biotechnology4004ElectiveAnimal inologyLaboratory0032ZOO667ZOO668ElectiveAnimal Behaviour4004ZOO669ElectiveAnimal Behaviour Laboratory0032ZOO630ElectiveEconomic Zoology4104ZOO646ElectiveEconomic Zoology Laboratory003234TotalL: LecturesT: TutorialsP: PracticalsCr: Credits* The students shall submit synopsis of any of these: Project (Laboratory/Field/ Review) Survey, Seminar.Page 4 of 6326

DAV UNIVERSITY, JALANDHARSCHEME OF COURSESM.Sc. (Hons.) ZoologySemester 4S. No.1PaperCodeCourse TypeCourse TitleBOT621CoreResearch Methodology2LTPCr3104Departmental Elective IIZOO6316Project II*83ORCoreZOO6482002Seminar-II*&6Departmental Elective II*Departmental Elective II (Choose any one theory course and the related laboratory eParasitology Laboratory0032ZOO636ElectiveAquaculture and Fisheries4004ZOO637ElectiveAquaculture and 4ZOO639ElectiveEntomology Laboratory0032ZOO670ElectivePopulation Genetics andEvolution4104ZOO671ElectivePopulation Genetics andEvolution Laboratory0032IIIIIIIVTotalL: LecturesT: TutorialsP: PracticalsCr: Credits*The student shall choose any one of these: Laboratory work/Field work/ Review/Survey/ Seminar/ Course of equivalent credits from theDepartmental Electives.Page 5 of 6318

DAV UNIVERSITY, JALANDHARSyllabiSEMESTER 1L T P Credits MarksCourse Title: Animal Physiology –ICourse Code: ZOO5304 1 04100Course Objective: The students will learn physiological aspects of body processes atsystem, organ, tissue and cellular level as well as their regulation.Unit-A 15 hoursNutrition and Digestion:Modes of Nutrition. Different types of nutrients, their sources and diseasesassociated with them.Histology and functions of gastrointestinal tract and its associated glands;mechanical and chemical digestion of food; role of gastrointestinal hormones;control and action of GI Tract secretions; absorptions of carbohydrates, lipids,proteins, water, minerals and vitamins.Unit-B 15 hoursTransport and Circulatory Mechanisms:Blood corpuscles, haemopoiesis, haemoglobin; coagulation of blood andhaemostasis.Physiological anatomy of mammalian heart, coronary circulation, cardiacmusculature and specialized tissue, origin and conduction of cardiac impulse,cardiac cycle, cardiac output and its regulation-Frank-Starling law of theheart, regulation of heart rate, blood pressure and its regulation; ECG – itsprinciple and significance.Unit-C15 hoursExcretion and Osmoregulation: Physiology of excretion, urine formation, urine concentration, wasteelimination, micturition, regulation of water balance, blood volume, bloodpressure, electrolyte balance, acid-base balance. Neuronal and hormonalregulationUnit-D15 hoursRespiratory system: Anatomy of Respiratory System, pulmonary ventilation, respiratory volumesand capacities; exchange and transport of gases, oxygen-haemoglobindissociation curve, waste elimination, neural and chemical regulation ofrespiration; circulatory and respiratory response to extreme conditions.Reference books:1. Barrington, E.U.W. Invertebrates Structure and Functions. Boston: Houghton MifflinCo., 1967.Page 6 of 63

DAV UNIVERSITY, JALANDHAR2. Cooper, G.M. and Hausman, E. The Cell: A Molecular Approach. Sinauer Associates,2013.3. Hall, J.E. Guyton and Hall Text Book of Medical Physiology, XIII edition, SaundersCompany, 2015.4. Hoar, W.S., General and comparative physiology, Adaptation and Environment, 3rded., Cambridge University Press, 1983.5. Tortora, G.J. and Grabowski, S. Principles of Anatomy & Physiology. XIEdition JohnWiley & sons, 2006.6. Victor P. Eroschenko.diFiore’s Atlas of Histology with Functionalcorrelations. XIIEdition. Lippincott W. & Wilkins, 2008.Page 7 of 63

DAV UNIVERSITY, JALANDHARCourse Title: Cell BiologyPaper Code: ZOO531Course Objective: To develop a comprehensive knowledgeof cell biology and role played by subcellular organelles inbiological functions of the cell.L T P Credits Marks4 0 04100UNIT-A12 hoursMembrane Structure and Function: Structure of model membrane, lipid bilayerand membrane protein diffusion, osmosis, ion channels, active transport,membrane pumps, mechanism of sorting and regulation of intracellular transport,electrical properties of membranes, extracellular matrix.Structural organization and function of intracellular organelles:dria and chloroplast, Golgi bodies, lysosomes, endoplasmic reticulum,peroxisomes, vacuoles, structure & function of cytoskeleton and its role inmotility.UNIT-B12 hoursCell cycle & its regulation: Mitosis and meiosis, Cell cycle regulation, Role ofthe cyclins and cyclin-dependent kinases, Cell cycle checkpoints.Cancer Biology: Genetic basis for cancer; Oncogenes, proto-oncogenes;Chromosome rearrangements and cancer; Tumor suppressor genes; Cellular rolesof tumor suppressor proteins, interaction of cancer cells with normal cells,necrosis, apoptosis, therapeutic interventions of uncontrolled cell growth.UNIT-C12 hoursCell Trafficking: Targeting proteins to endoplasmic reticulum, signal recognitionparticle, signal recognition particle receptor, protein folding and processing in ERprotein export from ER; Protein sorting and export from Golgi Apparatus; SNAREhypothesis; Protein import into Mitochondria, Import and sorting of chloroplastprotein.UNIT-D12 hoursCell signaling- Modes of cell signaling, Steroid hormone receptors, G-proteincoupled receptors; Regulation of signaling pathways, c- AMP pathway of signaltransduction; c-GMP, phospholipids and calcium ions, Ras, Raf, MAP kinasepathway, JAK–STAT pathway, bacterial chemotaxis and quorum sensing, celladhesion and roles of different adhesion molecules in signalling.Page 8 of 63

DAV UNIVERSITY, JALANDHARReference books:1. Alberts, B. Bracy, P. Lewis , J. Raff, M. Roberts K and Watson, J. (eds) (2008).Molecular Biology of the Cell (5th Ed.), Garland Publishing , New York.2. Avers, C. J. (1976). Cell Biology, Van Nostrand Reinhold, New York.3. Cooper, G. M. (2015). The cell, A Molecular Approach (7th Ed)ASM press,Washington, D. C.4. Darnell, J. Lodish, H. and Baltimore, D. (2007). Molecular Cell Biology, 6th edition,Freeman, New York.5. Derobertis, E. D. P. and Derobertis, E.M.F. (2011). Essentials of Cell and MolecularBiology(8th Ed) Hold Saunders – Philadelphia.6. Karp G. (2013). Cell and Molecular Biology. Concepts and Experiments, 7th EditonJohn Wiley and Sons, Inc. New York, Brisbane, Toronto.7. Loewy, A. G. , Siekevitz, P, Menningee, J. R. , and Allant, J. A. N. (1999). Cellstructure and Functions. An integrated Approach 3rd edition. Saunders CollegePublishing, Philadelphia, London.8. Pollard. T.D. and Earnshaw, W.C. (2002) Cell Biology. Saunders, PhiladelphiaLondon. New York, St. Luis Sydney, Toronto.9. Powar, C. B. (1990). Cell Biology. Himalaya Publishing House, Bombay.10. Sadava, D. E. (1993). Cell Biology – Organelle, Structure and Fucntions. H. Jonesand Bartlett- Boston.Page 9 of 63

DAV UNIVERSITY, JALANDHARCourse Title:Molecular BiologyPaper Code: ZOO532L T P Credits MarksCourse Objective: A comprehensive knowledge of 4 0 04100molecular aspects of biological function at the molecularlevel, particular emphasis on the structure and regulation of genes, as well as, the structureand synthesis of proteins and applications of these concepts in human medicine and health,agriculture, study evolution and other areas.UNIT-A15 hoursDNA and its various forms, super coiling of DNA, DNA melting, repetitivesequences, cot and rot curves, C value paradox, DNA supercoiling. Prokaryotic &eukaryotic DNA replication, enzymes and accessory proteins involved in DNAreplication, replication origin & replication fork, fidelity of replication, extrachromosomal replicons, DNA damage and repair mechanisms, gene amplification,mobile genetic elements, homologous and site specific recombination.UNIT-B15 hoursProkaryotic and eukaryotic transcription, RNA polymerase, transcription factors,regulatory elements, transcriptional activator, repressor & mechanism oftranscription regulation, post-transcriptional processing of mRNA, rRNA & tRNA,RNA editing, structure and function of different types of RNA, RNA transport.UNIT-C15 hoursProtein synthesis and processing: Ribosome structure, genetic code, prokaryotic &eukaryotic translation, the translation machinery, mechanism and regulation oftranslation & translation proof-reading, translational inhibitors, Post- translationalmodification of proteins and intracellular protein targeting, import into nucleus,mitochondria and peroxisome.UNIT-D15 hoursControl of gene expression at transcription and translation level (regulating theexpression of phages, viruses, prokaryotic and eukaryotic genes, role of chromatinin gene expression and gene silencing).Reference books:1. Alberts, B. Bracy, P. Lewis , J. Raff, M. Roberts K and Watson, J. (eds) (2008).Molecular Biology of the Cell (5th Ed.), Garland Publishing , New York.Page 10 of 63

DAV UNIVERSITY, JALANDHAR2. Cooper, G. M. (2015). The cell, A Molecular Approach (7th Ed)ASM press,Washington, D. C.3. Darnell, J. Lodish, H. and Baltimore, D. (2007). Molecular Cell Biology, 6th edition,Freeman, New York.4. Derobertis, E. D. P. and Derobertis, E.M.F. (2011). Essentials of Cell and MolecularBiology(8th Ed) Hold Saunders – Philadelphia.5. Karp G. (2013). Cell and Molecular Biology. Concepts and Experiments, 7th EditonJohn Wiley and Sons, Inc. New York, Brisbane, Toronto.6. Loewy, A. G. , Siekevitz, P, Menningee, J. R. , and Allant, J. A. N. (1999). Cellstructure and Functions. An integrated Approach 3rd edition. Saunders CollegePublishing, Philadelphia, London.7. Pollard. T.D. and Earnshaw, W.C. (2002) Cell Biology. Saunders, PhiladelphiaLondon. New York, St. Luis Sydney, Toronto.8. Powar, C. B. (1990). Cell Biology. Himalaya Publishing House, Bombay.9. Sadava, D. E. (1993). Cell Biology – Organelle, Structure and Fucntions. H. Jonesand Bartlett- Boston.10. Genes IX (2008). Benjamin Lewin (Jones and Bartlett Publishers).11. Molecular cloning: A laboratory manual (2000). J. Sambrook, E.F. Fritish and T.Maniatis (Cold Spring Harbor Laboratory Press, New York).Page 11 of 63

DAV UNIVERSITY, JALANDHARCourse Title: Cell and Molecular Biology LaboratoryLT P CreditsMarksCourse Code: ZOO5330050 Preparation of permanent slides of cell division Preparation of permanent slide of polytene chromosomes Isolation of DNA from prokaryotes/eukaryotes Quantification of DNA using UV-Visible spectrophotometer Designing of primers and ePCR Amplification of DNA by PCR Agarose gel electrophoresis Comet assay for estimation of DNA damagePage 12 of 6332

DAV UNIVERSITY, JALANDHARCourse Title: ImmunologyPaper Code: ZOO534Course Objective: To acquaint students with the differentcomponents of immune system and their functioning.L T P Credits Marks4 0 04100UNIT-A 20 hoursConcepts in immunology: Specificity, discrimination of self from nonself and memoryCells and organs of immune system: Lymphocytes, Monocyes,Eosinophils, Basophils, Neutrophils, Dendritic cells; Lymphoid organsAntigens: Characteristics of antigens, antigenicity vs. immunogenicity,epitopes, B and T cell epitopes, adjuvantsAntibodies: Structure, Types and Functions of antibodies; concept ofmonoclonal and polyclonal antibodiesUNIT-B10 hoursAntigen-antibody interactions: Precipitation, Agglutination, Immunodiffusion,Immunoelectrophoresis, IFA, ELISA and Flow cytometryUNIT-C15 hours Immunity: Innate and acquired immunity, Humoral immunity, Cellmediated immunity, Complement system: Nomenclature of complement components,activation pathways of complement system Cytokines: Various cytokines and their roleUNIT-D 15 hoursAutoimmunity: Mechanisms of autoimmunityHypersensitivity: General concept, types of hypersensitivityVaccines: General concept, types of vaccinesReference books:1. Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology. 6th editionSaunders Publication, Philadelphia. 2007. Print2. Delves P, Martin S, Burton D, Roitt IM. Roitt’s Essential Immunology. 11th editionWiley Blackwell Scientific Publication, Oxford. 2006. Print3. Goldsby RA, Kindt TJ, Osborne BA. Kuby’s Immunology. 6th edition W.H. Freemanand Company, New York. 2007. PrintPage 13 of 63

DAV UNIVERSITY, JALANDHAR4. Murphy K, Travers P, Walport M. Janeway’s Immunobiology. 7th edition GarlandScience Publishers, New York. 2008. Print5. Peakman M, and Vergani D. Basic and Clinical Immunology. 2nd edition ChurchillLivingstone Publishers, Edinberg. 2009. PrintPage 14 of 63

DAV UNIVERSITY, JALANDHARCourse Title: Immunology LaboratoryCourse Code: ZOO535L TP Credit Marks0 0 3 21. Identification of human blood groups.2. To separate serum from the blood sample(demonstration).3. To perform Total Leukocyte Count of the given blood sample.4. To perform Differential Leukocyte Count of the given blood sample.5. To perform immunodiffusion by Ouchterlony method.6. SDS-PAGE electrophoresis of immunologic effector proteins.7. Immunoelectrophoresis8. Western Blotting9. ELISAPage 15 of 6350

DAV UNIVERSITY, JALANDHARCourse Title: Principles of BiochemistryPaper Code: BCH 524L4T P Credits Marks0 04100Course Objective: The course is intended for master’scourse students. This course is a broad survey of all the major concepts of biochemistry withemphasis on all the important categories of biomolecules and their biochemistry.Unit A (15 hours)Introduction to BiochemistryWater as a biological solvent. Weak acids and bases. pH and buffers. Henderson-Hasselbalchequation. Physiological buffers. Fitness of the aqueous environment for living organisms.CarbohydratesStructure of monosaccharides. Stereoisomerism and optical isomerism of sugars. Reactionsof aldehyde and ketone groups. Ring structure and anomeric forms, mutarotation. Reactionsof sugars due to hydroxyl groups. Important derivatives of monosaccharides, disaccharidesand trisaccharides (structure, function and occurrence of important ones). Structure,occurrence and biological importance of monosaccharides, oligosaccharides andpolysaccharides - cellulose, chitin, agar, algenic acids, pectins, proteoglycans, sialic acids,blood group polysaccharides, glycogen and starch. Bacterial cell wall polysaccharides.Glycoproteins.ProteinsIntroduction to proteins. Classification based on solubility, shape, composition and functions.Amino acids: common structural features, stereoisomerism and RS system of designatingoptical isomers. Classification and structures of standard amino acids as zwitterion inaqueous solutions. Physical and chemical properties of amino acids. Titration of amino acids.Separation of amino acids. Essential amino acids.Structure of peptide bond. Solid-phase synthesis of peptides. Peptide sequencing. Chemicaland enzymatic cleavage of polypeptide chains and separation of peptides. Levels of structurein protein architecture. denaturation and renaturation of proteins. Behaviour of proteins insolutions. Salting in and salting out of proteins. Structure and biological functions of fibrousproteins (keratins, collagen and elastin), globular proteins (haemoglobin, myoglobin),lipoproteins, metalloproteins, glycoproteins and nucleoproteins.Page 16 of 63

DAV UNIVERSITY, JALANDHARUnit B (15 hours)Nucleic AcidsNature of genetic material. Evidence that DNA is the genetic material. Composition of DNAand RNA. Generalized structural plan and Nomenclature of nucleic acids. DNA double helix.Structure and roles of different types of RNA. Size of DNA in prokaryotes and eukaryotes.Central dogma of molecular biology. Concepts of gene, genome and chromosome.PorphyrinsPorphyrin nucleus and classification of porphyrins. Important metalloporphyrins occurring innature. Detection of porphyrins. Bile pigments – chemical nature and physiologicalsignificance.LipidsDefinition and classification of lipids. Fatty acids: introduction, classification, nomenclature,structure and properties of saturated and unsaturated fatty acids. Essential fatty acids,prostaglandins. Triacylglycerols: nomenclature, physical properties, chemical properties andcharacterization of fats – hydrolysis, saponification value, rancidity of fats, Reichert-MeisselNumber and reaction of glycerol. Biological significance of fats. Glycerophospholipids(lecithins, lysolecithins, cephalins, phosphatidylserine, phosphatidylinositol, plasmalogens),sphingomyelins, glycolipids – cerebrosides, gangliosides. Properties and functions ofphospholipids, isoprenoids and sterols.Unit C (15 hours)Introduction to MetabolismGeneral features of metabolism, experimental approaches to study metabolism – intactorganisms, bacterial mutants, tissue slices, radioisotopes.Carbohydrate MetabolismReactions and energetics of glycolysis. Alcoholic and lactic acid fermentations. Reactionsand energetics of TCA cycle. Gluconeogenesis, glycogenesis and glycogenolysis. Reactionsand physiological significance of pentose phosphate pathway. Regulation of glycolysis andTCA cycle. Photosynthesis – a brief review.Electron Transport Chain and Oxidative PhosphorylationStructure of mitochondria. Sequence of electron carriers. Sites of ATP production. Inhibitorsof electron transport chain. Chemiosmotic hypothesis. Inhibitors and uncouplers of oxidativephosphorylation. Transport of reducing potentials into mitochondria.Unit D (15 hours)Page 17 of 63

DAV UNIVERSITY, JALANDHARLipid MetabolismIntroduction. Hydrolysis of triacylglycerols. Transport of fatty acids into mitochondria. βoxidation of saturated fatty acids. ATP yield from fatty acid oxidation. Biosynthesis ofsaturated and unsaturated fatty acids. Metabolism of ketone bodies. Oxidation of unsaturatedand odd chain fatty acids. Biosynthesis of triglycerides and important phospholipids,glycolipids, sphingolipids and cholesterol. Regulation of cholesterol metabolism.Amino Acid MetabolismGeneral reactions of amino acid metabolism – transamination, oxidative deamination anddecarboxylation. Urea cycle. Degradation and biosynthesis of amino acids. Glycogenic andketogenic amino acids.Nucleotide MetabolismSources of atoms in the purine and pyrimidine nucleotides. Biosynthesis and degradation ofpurines and pyrimidines. Regulation of purine and pyrimidine biosynthesis.Porphyrin MetabolismBiosynthesis and degradation of

DAV UNIVERSITY, JALANDHAR Page 4 of 63 SCHEME OF COURSES M.Sc. (Hons.) Zoology Semester 3 S. No. Paper Code Course Type Course Title L T P Cr 1 ZOO660 Core Genetics 4 0 0 4 2 ZOO661 Core Genetics Laboratory 0 0 3 2 3 ZOO662 Core Developmental Biology 4 0 0 4 4 ZOO663

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