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WEEKLY BULLETIN ON OUTBREAKSAND OTHER EMERGENCIESWeek 49: 2 - 8 December 2019Data as reported by: 17:00; 8 December 2019REGIONAL OFFICE FORAfricaWHO Health Emergencies Programme621Ongoing eventsNew event1251HumanitariancrisesOutbreaks1 179 011 1Senegal1GuineaBurkina FasoCôte d’IvoireSierra léone7 49 969 5404 690 1895 2026 290Nigeria804 1793 787 192BeninTogo55 47631 569 5Niger2 089 21South Sudan839 4Central AfricanRepublic 16Cameroon1 170 1427511 071 53 1 638 4006118 2269 05811 434 0Rift Valley FeverEbola virus diseaseUganda1 14 758 37Burundi7 392 429 2 8231 064 64 76195Comoros101ZambiaMalaria144 00MozambiquePlagueFloodsCasesDeathsKenya76 060 0Leishmaniasis02 788 3426 505 465AngolaChikungunyacVDPV235 43050 8Dengue feverCholera9 43754 739 00Yellow feverLassa feverEthiopia233 320 2 209Hepatitis EMonkeypox3 9630Democratic Republicof Congo0Humanitarian crisisMeasles1 194 0ChadCongoLegend025 916 25552 0GhanaLiberia1Mali3 1NamibiaCountries reported in the documentNon WHO African Region6 746 56WHO Member States with no reported eventsN3 0South AfricaLesotho5920 0 0WESGraded events †3152Grade 3 eventsGrade 2 eventsGrade 1 eventsProtractedProtracted33eventseventsProtracted 2 eventsProtractedProtracted11eventsevent22Health Emergency Information and Risk Assessment202137Ungraded events1Health Emergency Information and Risk Assessment

OverviewContents2Overview3 - 6 Ongoing events78Summary of majorissues, challengesand proposed actionsAll events currentlybeing monitoredThis Weekly Bulletin focuses on public health emergencies occurring in the WHOAfrican Region. The WHO Health Emergencies Programme is currently monitoring63 events in the region. This week’s main articles cover key new and ongoingevents, including: Measles in Democratic Republic of the Congo Ebola virus disease in Democratic Republic of the Congo Lassa fever in Liberia Humanitarian crisis in Burkina Faso.For each of these events, a brief description, followed by public health measuresimplemented and an interpretation of the situation is provided.A table is provided at the end of the bulletin with information on all new andongoing public health events currently being monitored in the region, as well asrecent events that have largely been controlled and thus closed.Major issues and challenges include: The protracted measles outbreak in Democratic Republic of the Congocontinues to expand, with high morbidity and mortality. Several othercountries in the African region are also experiencing measles outbreaks, aswell as many countries in other parts of the world. The underlying factor forthe measles outbreaks in the African region is the inability of the vaccineadministration systems to reach vulnerable children, rather than low uptakeof the vaccines by the recipients – an increasing phenomenon seen in thedeveloped world. Some of the reasons for the low immunization coveragein the African region include inadequacies in healthcare systems and socialdislocation due to armed conflicts, poverty, other disasters, etc. The currentresurgence of measles is concerning. Health authorities in the African regionand the global partners need to double efforts to improve the performanceof national immunization programmes to attain the minimum requiredimmunization coverage. The number of reported Ebola virus disease (EVD) cases in DemocraticRepublic of the Congo remains low during the reporting week, as mostresponse activities have resumed following the heightened insecurity and civilunrest. While the operational performance indicators were drastically affected,the impact of the disruption in response interventions is not yet evident onthe evolution of the outbreak. We remain cautiously optimistic as we continueto monitor the trends. It is commendable that all the Ebola responders fromthe national authorities, WHO and partners showed exceptional resilienceand determination to continue with the response and see the end of the EVDoutbreak.2Health Emergency Information and Risk Assessment

Ongoing events157MeaslesDemocratic Republic of the CongoEVENT DESCRIPTIONThe protracted measles outbreak in Democratic Republic ofthe Congo continues to expand, with increasing trends inweekly incidence cases since week 27, when a short declinewas observed over a period of 10 weeks. Since our last reporton 11 November 2019 (Weekly Bulletin 45), 35 742 additionalsuspected measles cases and 707 additional deaths have beenreported across the country, including in 53 new health zoneswith confirmed epidemics. In week 47 (week ending 24 November2019), a total of 7 230 suspected measles cases, including 136deaths (case fatality ratio 1.9%) were reported, compared to8 660 cases with 152 deaths reported in week 46. Two newhealth zones in Haut-Uele province, Isiro and Niangara, attainedepidemic threshold during the reporting week. The most affectedprovinces were Mai-Ndombe (n 1431), Equateur (n 982), Kwilu(n 919) and South-Kivu (n 714), which contributed to 56% ofall cases reported during the week. Mortality was highest in theprovinces of Mai-Ndombe (n 44, CFR: 3%), Equateur (n 33,CFR 3%) and Bas-Uele (n 30, CFR: 3%), accounting for about80% of all deaths during the reporting week.From 1 January to 2 December 2019, a total of 269 079suspected measles cases, including 5 430 deaths (CFR 2%) havebeen reported from all 26 provinces in Democratic Republic ofthe Congo. The outbreak has been laboratory confirmed in 241(46%) health zones. The provinces of Kasai (35 195), Tshopo(33 419), Kwili (21 366) and Mai-Ndombe (20 250) accountfor 41% of the cumulative cases reported since the beginningof 2019. Cases continue to be reported from Ituri and NorthKivu provinces, which are concomitantly affected by the ongoingEbola outbreak, with 10 845 cases (CFR 0.6%) and 5 743 cases(CFR 0.3%) reported respectively, since the beginning of theyear.269 079Cases5 430Deaths2.0%CFRGeographical distribution of suspected measles cases and deaths in DemocraticRepublic of the Congo, 1 January - 2 December 2019Distribution of suspected measles cases and case-fatality ratio in DemocraticRepublic of the Congo, weeks 1 - 47To date, vaccination campaigns have been conducted in 165(31.8%) of the 519 health zones and a total of 5 277 827 childrenwere vaccinated. A decreasing trend in the weekly case incidencehas been observed in vaccinated areas.PUBLIC HEALTH ACTIONS The National Steering Committee sat on 3 December 2019 to WHO’s response interventions focusing on case management are carriedreview, strategize and prepare for a vaccination campaign inother provinces.out jointly with other partners including Médecins Sans Frontières, ActionsContre la Faim and Médecins du Monde. From 25 to 29 November 2019, WHO supported vaccination Risk communication and community mobilization using various channelscampaigns in 14 hotspot and priority areas in six provinces. Médecins Sans Frontières supported the vaccination ofchildren aged 6-59 months in 9 out of 27 health areas ofthe Koshibanda Health Zone. Overall 16 294 children werevaccinated, representing a vaccination coverage of 109%. Médecins Sans Frontières supported case management for1 847 simple cases of measles and 91 cases of measles withcomplications, in 9 out of 27 health areas in Koshibanda The measles case management protocol has beendisseminated to improve case management and reducemortality. The Emergency Medical Team has been deployed to hotspothealth zones since 27 December 2019 with support fromWHO.Go to overviewsuch as religious fora, community radio stations, schools and NonGovernmental Organisations, have been strengthened to improve uptake ofthe vaccination campaigns.SITUATION INTERPRETATIONThe measles outbreak in Democratic Republic of the Congo has become the world’slargest and most severe measles epidemic. This outbreak has already caused moredeaths compared to the ongoing EVD outbreak. Sub-optimal routine immunizationcoverages and high levels of malnutrition have contributed to the rapid expansion ofthe measles epidemic and its associated high mortality rates. Furthermore, the underperformance of case-based surveillance has impaired rapid detection of suspectedmeasles cases, which is necessary to guide timely and effective outbreak responseinterventions. In order to put an end to this outbreak, there is a need to strengthenroutine and reactive immunization activities, measles case-based surveillance andcase management.Go to map of the outbreaks3Health Emergency Information and Risk Assessment

157Ebola virus diseaseDemocratic Republic of the CongoEVENT DESCRIPTIONThe Ebola virus disease (EVD) outbreak in North Kivu, SouthKivu and Ituri provinces in Democratic Republic of the Congocontinues, with response operations cautiously being restoredfollowing the intense insecurity and civil unrest. Since our lastreport on 1 December 2019 (Weekly Bulletin 48), there havebeen seven new confirmed cases and six new deaths reportedfrom four health zones, Beni, Mabalako, Mandima and Oicha.In the past 21 days (17 November to 7 December 2019), fourhealth zones and 11 health areas reported confirmed cases,with the principle hot spots being Mabalako (43%; n 12 cases),Mandima (25%; n 7), Beni (21%; n 6) and Oicha (11%; n 3).3 320Cases2 209Deaths67%CFRGeographical distribution of confirmed Ebola virus disease cases reportedfrom 17 November - 7 December 2019, North Kivu, South Kivu and Ituri provinces,Democratic Republic of the CongoAs of 7 December 2019, a total of 3 320 EVD cases, including3 202 confirmed and 118 probable cases have been reported. Todate, confirmed cases have been reported from 29 health zones:Ariwara (1), Bunia (4), Komanda (56), Lolwa (6), Mambasa (78),Mandima (346), Nyakunde (2), Rwampara (8) and Tchomia (2) inIturi Province; Alimbongo (5), Beni (693), Biena (18), Butembo(285), Goma (1), Kalunguta (193), Katwa (651), Kayna (28),Kyondo (25), Lubero (31), Mabalako (407), Manguredjipa (18),Masereka (50), Musienene (84), Mutwanga (32), Nyiragongo (3),Oicha (65), Pinga (1) and Vuhovi (103) in North Kivu Provinceand Mwenga (6) in South Kivu Province.As of 7 December 2019, a total of 2 209 deaths were recorded,including 2 091 among confirmed cases, resulting in a casefatality ratio among confirmed cases of 65% (2 091/3 202). Thecumulative number of health workers remains 163, which is 5%of the confirmed and probable cases to date.Contact tracing is ongoing in five health zones. A total of 2 907contacts are under follow-up as of 7 December 2019, of which2 318 (80%) have been seen in the past 24 hours. Alerts in theaffected provinces continue to be raised and investigated. Of4 128 alerts processed (of which 3 956 were new) in reportinghealth zones on 7 December 2019, 4 022 were investigated and391 (10%) were validated as suspected cases.PUBLIC HEALTH ACTIONS Response activities have cautiously restarted in Beni,Butembo and Mangina, but the security situation remainstense and response activities are still severely compromised. Water, sanitation and hygiene (WASH) activities continue, with IPC briefingsession for 298 providers in six health zone (Mangina, Butembo, Musienene,Kalunguta, Mambasa and Bunia); a supply of 49 070 litres of water wasprovided for handwashing facilities in Mambasa and Buinia health zones. Community awareness and mobilization messages are being updated,revised and harmonized and have been pre-tested by the commission andwill subsequently be shared in coordination and sub-coordination activities.SITUATION INTERPRETATIONThe general decline in reported new cases has continued, although with responseactivities compromised in Beni, Butembo and Mangina, it is possible that casesand community deaths have not been recorded. The trend, especially for this andthe coming weeks, should be interpreted cautiously as we watch the impact of thedisruption in response operations due to heightened insecurity and civil unrest. It iscritical that all areas of response remain effective, engaged and fully resourced. As of 7 December 2019, a cumulative total of 256 229 peoplehave been vaccinated since the start of the outbreak inAugust 2018. Point of Entry/Point of Control (PoE/PoC) screeningcontinues, with over 125 million screenings to date. A totalof 104/109 (95%) PoE/PoC transmitted reports as of 7December 2019.4Go to overviewHealth Emergency Information and Risk AssessmentGo to map of the outbreaks

157Lassa feverLiberiaEVENT DESCRIPTIONLassa fever remains a public health challenge in Liberia, withincreasing number of new cases seen in recent weeks. In week47 (week ending 24 November 2019), five new confirmed Lassafever cases with two deaths were reported from two counties:Grand Bassa (4 cases, 1 death) and Nimba (1 case, 1 death).The case-patient from Nimba County was a 19-year-old pregnantfemale resident of Sanniquellie Mah district, an area known tobe endemic for Lassa fever in Liberia. She presented to a localhospital on 19 November 2019, nine days after symptom onset.The diagnosis of Lassa fever was confirmed on 22 November2019 when test results returned positive for Lassa virus infectionby reverse transcriptase-polymerase chain reaction (RT-PCR)at the National Public Health Reference Laboratory of Liberia(NPHRL). She died while undergoing clinical care. The fourcases from Grand Bassa County were residents of District #3A,another area known to be endemic for the disease, and werenotified to the national authorities between 18 and 24 November2019. The case-patients presented to a local hospital in the andwere confirmed for Lassa virus infection by RT-PCR.From 1 January to 24 November 2019, a cumulative total of 169suspected Lassa fever cases were reported across the country.Of the 169 suspected cases, 120 were sampled and tested forLassa fever by reverse transcriptase-polymerase chain reaction(RT-PCR) at the National Public Health Reference Laboratory ofLiberia (NPHRL), with testing 46 positive and 74 negatives. Ofthe 46 confirmed cases, 14 died, giving a case fatality ratio of30%) among confirmed cases.The confirmed cases originated from five counties, namely;Grand Bassa (17 cases, 3 deaths), Bong (14 cases, 6 deaths),Nimba (10 cases, 3 deaths), Montserrado (2 cases, 1 death),Grand Kru (2 cases, zero deaths), and Margibi (1 case, 1 death).The median age of the confirmed cases is 25.5 years (IQR 14– 39). Females constitute 61% (n 28) of the confirmed cases.The case fatality ratio is 44.4% (8/18) among males and 21.4%(6/28) among females. A total of 179 contacts are currentlybeing followed across four counties.PUBLIC HEALTH ACTIONS Public health responses to Lassa fever events continue tobe mounted at the sub-national level under the leadership ofthe respective County Health Teams (CHT). At the nationallevel, the National Public Health Institute of Liberia (NPHIL),with support from WHO, US CDC, and other partnerscontinue to monitor the situation and provide technicalsupport in responding to these events.95Cases20Deaths21%CFRGeographical distribution of confirmed Lassa fever cases and deaths in Liberia,1 January - 24 November 2019 Dedicated treatment centres for Lassa fever remain operational acrossdesignated sites. There are two case-patients currently in admission atthe treatment centre in Grand Bassa County. WHO has donated 375 dosesof ribavirin to support clinical management of cases and these are beingpropositioned at designated treatment centres. Mentoring of healthcareworkers on standard and transmission-based infection control andprevention practices are routinely undertaken. Community engagement and risk communication activities are beingroutinely implemented in affected communities as part of outbreakresponse measures.SITUATION INTERPRETATIONThe current increase in cases of Lassa fever in Liberia could be an indication ofthe start of the peak seasonal pattern, which usually begins at the onset of thedry season. Changes in ecological and environmental factors over the years,coupled with improve surveillance for Lassa fever, continue to lead to the yearlyincreasing trend of Lassa fever cases reported. The primary factors that exposepeople to infectious rodents remain in the community and need to be tackled.The national authorities and partners in Liberia need to strengthen surveillancefor early detection and management of cases. Additionally, engagement with thecommunities and mainstreaming the One Health approach into preparedness andresponse activities are crucial to reducing Lassa fever morbidity and mortality. In the affected counties, enhanced surveillance includingactive case search, case investigation and contact tracingare ongoing. Outbreak case definitions as well as screeningtools for triaging patients are being used at local healthfacilities for case identification.Go to overviewGo to map of the outbreaks5Health Emergency Information and Risk Assessment

157Humanitarian crisisBurkina FasoHumanitarian snapshot in Burkina Faso,as of 15 November 2019EVENT DESCRIPTIONThe humanitarian crisis in Burkina Faso continues, with insecurity,the main driver, affecting mainly the Sahel, Centre-North, NorthEast and Boucle du Mouhoun provinces. Since the start of 2019,there have been more than 500 security incidents, causing 1 643deaths, recorded in 34 out of 45 of the provinces in the country.Sahel and Centre-North have registered 63% of all incidents.According to OCHA, there are 486 360 internally displacedpersons (IDP) in the 13 regions of the country, an increase of68% on the figures released on 23 September 2019 (289 591).Most IDPs are women (35.7%) and children (48.7%) and aremainly located in the Centre-North (55.6%) and Sahel (33%). Thehumanitarian response in the Sahel and Centre-North provinces iscompromised as certain areas are inaccessible.Number of Security Incidents(in October 2019)01-56 - 1011 - 2021 - 30 30XXPUBLIC HEALTH ACTIONS 6Multidisciplinary mobile clinics continue to be deployed inCentre-North in collaboration with ALIMA, since 1 September2019, with financial contributions from WHO; with mobileclinics established in Sahel in collaboration with Médicines duMonde (MDM), Spain, also supported by WHO. A preventative meningitis vaccination campaign reached256 842/330 627 children aged 2-14 years in the Sahel, withvaccine provided by the ICG, in response to a request by WHO. WHO has supported the Central Emergency ResponseOperations Centre in organizing Incident Management Trainingin Kaya, Centre-North, as well as a workshop for the operationalemergency medical team in the country. WHO continues to support implementation of the HealthResource Availability Mapping System, which will start in midDecember 2019, as well as the Surveillance System of Attackson Healthcare for continued data collection.Go to overviewHealth Emergency Information and Risk AssessmentNord160,741Centre-Nord31,998 270,476Boucle duMouhoun1,051OuagadougouEstCentrePlateau Central8,588 Ouest Centre Est558284Cascades268 Sud-OuestHealth workers are increasingly being attacked, with a head nursekilled in the Sahel region on 29 November 2019, while the chairof the management committee of a health promotion centre andthe chair of a village development committee were kidnapped inthe Sahel region two weeks ago. They are still unaccounted for.Seventy-three mobile phones from the Auto-Visual AFP Detectionand Reporting group were stolen and destroyed by armed groups.At least 85 health facilities have closed, with 93 partially functionalas of 3 December 2019. This leaves at least one million peoplewithout access to health care.The nutritional situation in Sahel and Centre-North is worsening,according to the result of a SMART survey published on 27November 2019. The prevalence of acute malnutrition is veryhigh; global acute malnutrition is 11.6-19.7% and severe acutemalnutrition is 1.5-7% among IDP children aged 6 to 59 months.Internally Displaced Persons 2Sahel WHO continues to coordinate the

on 11 November 2019 (Weekly Bulletin 45), 35 742 additional suspected measles cases and 707 additional deaths have been reported across the country, including in 53 new health zones with confirmed epidemics. In week 47 (week ending 24 November 2019), a total of 7 230 suspected measles cases, including 136

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