INDIAN INSTITUTE OF SCIENCE (IISc) Bangalore

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INDIAN INSTITUTE OF SCIENCE (IISc)Bangalore

IISc: THE DIVISIONAL STRUCTUREBiologicalSciencesPhysical andMathematical rdisciplinaryResearchElectricalSciences

Division of Biological Sciences(76 Serving faculty members) ( 250 publications/year)Microbiology andCell BiologyMolecularBiophysics Unit(1941)(1971)Prof. U. VijayraghavanProf. N. SrinivasanCentre forEcological Sciences(1983)Molecular Reproduction,Development andGeneticsCentre forNeuroscience(2009)Prof. R. BalakrishnanProf. S. VisweswariahBiochemistry(1921)Prof. C. Jayabaskaran(1989)Central AnimalFacility(1971)Prof. K. SomasundaramProf. A. MurthyCentre for InfectiousDisease Research(2014)Prof. D. Nandi 60 PhDsgraduateeach year

Other Centres for Interdisciplinary Research1. Centre for Biosystems Science and Engineering(BSSE)2. Centre for Nano Science and Engineering (CeNSE)3. National Mathematics Initiative (IISc node; MathBio@IISc)4. Centre for Brain Research (CBR)

Funding generated by the Departments/Centres in theDivision of Biological Sciences (2014-18)Total: INR 402 crores (US 57 million)(Excludes IISc and DBT-IISc Funds)MRDGCAF CIDRBCCESMBUCNSMCBDBT-IISc Funds2012-2018: 70 crores2019-2021: 78 crores

Funding sourcesIndo-Swedish grantIndo-Australia grantIndo-Israel grantIndo-Russian grant

1. Disease Biology1.1 Infectious disease biology(Viruses, bacteria and fungi)Principal Investigators from DBS:Dipshikha Chakravortty, S. Vijaya,K. N. Balaji, P. Ajitkumar, AmitSingh, S. Mahadevan, N. Ganesh,DipankarNandi,SaibalChatterjee, and Utpal Tatu.Co-investigators from otherdivisions: Jagadeesh Gopalan(Aerospace Engineering), AshokRaichur (Materials Engineering),G. Mugesh (Inorganic PhysicalChemistry), and S. Umapathy(Inorganic Physical Chemistry).

1. Disease Biology1.2 Non-communicable diseases(Cancer, neuronal disorders,cardiac and other disorders)Principal Investigators from DBS:Kumar Somasundaram, SatheeshRaghavan,PaturuKondaiah,Annapoorni Rangarajan, Sujit Sikdar,Vijayalakshmi Ravindranath, RaviSundaresan,SandeepM.Eswarappa, and Nagasuma Chandra.Co-investigatorsfromotherdivisions: K. R. Prasad (IPC),Debnath Pal (CDS), H. S. Atreya(NMR Centre), Bharadwaj (ECE), andG. Rangarajan (Mathematics).

2.1Cell,architecturetissueandorganPrincipal Investigators from DBS:Sachin Kotak, Purusharth I. Rajyaguru,P. N. Rangarajan, Deepak Nair, G.Subba Rao and Ramray Bhatt.Co-investigators from other divisions:Prerna Sharma (Physics), AmbarishGhosh (CeNSE)Cell, tissue and organ architecture2. Biological function and form throughcomplex interactionsCellular processes/functionOrganization and diseasePrevention and cureCell typesVirusBacteriaYeast/FungusMammalianTissue typesPlantSkinNeuronHeart/liver/lung/muscleOrgan typesPlantBrainLungHeart

2.2 NetworksbehaviorindevelopmentandPrincipal Investigators from DBS: UtpalNath,UshaVijayraghavan,PolaniSeshagiri, Rishikesh Narayanan, BalajiJayaprakash, Supratim Ray, Aditya Murthy,S. P. Arun, and Sridharan Devarajan.Co-investigators from other divisions:Rajesh Sundaresan (ECE), RameshHariharan (CSA), G. K Ananthasuresh(ME), Ashitava Ghosal (ME), RadhakantPadhi (AE), Sriram Ganapathy (EE), upradeepa,(CeNSE), K. V. S Hari (ECE), Partha Talukdar(CDS), Sriram Ganapathy (EE)Networks in Development and Behaviour2. Biological function and form throughcomplex interactions

2.3 Aging and regenerationPrincipal Investigators from DBS:Deepak Saini, Narendra Ramanan, NRavi Sundaresan, Varsha Singh,Upendra NongthombaCo-investigatorsfromotherdivisions: Ambarish Ghosh, ManojVerma, Rudra Pratap (CeNSE), S.Umapathy (Inorganic and PhysicalChemistry), Kaushik Chatterjee(Materials Engineering) and A.Muthuvel (Electrical Engineering)Aging and Regeneration2. Biological function and form throughcomplex interactionsDisorders and pathologyIntervention & TherapyDriver & MechanismsNeuronalregeneration andbasis of longevityAge associatedinflammation anddegenerationAge associated musclewasting and myopathies

3. Biomolecular structure, function and design3.1 Structure elucidationsand functional studiesPrincipal Investigators fromDBS: B. Gopal, MahavirSingh, K. Suguna, TanweerHussain,SiddharthaP.Sarma, Somnath Dutta,Aravind Penmatsa, UmeshVarshney, D. N. Rao, C.Jayabaskaran, Patrick D’Silva,and Shikha Laloraya.Nucleic eryX-rayCo-investigators from otherdivisions: G. Mugesh (IPC),Santanu Bhattacharya (OC).Modular enzymesTransportmechanismsAnimal toxins &metabolitesMolecules inhuman disease

3. Biomolecular structure, function and design3.2 Computationaland bioinformaticsbiologySimulationsBig DataPrincipal Investigators from DBS:N. Srinivasan, A. Srivastava, andNagasuma Chandra.MembranesViral a(Chemical iganticassembliesDiseases &drugs

3. Biomolecular structure, function and design3.3 Molecular designPrincipal Investigators fromDBS: V. Nagaraja, SandhyaVisweswariah,RaghavanVaradarajan, Saumitra Das,and Jayanta Chatterjee, A.Srivastava.H109Co-investigators from otherdivisions: Ganapathy Ayappa(Chem. Eng.), Jaydeep Basu(Physics), Vijay Natarajan(CSA), Siddharth Jhunjhunwala(Bioeng), Rahul Roy (Chem.Eng.), N. Jayaraman (OC), andAshok Raichur (ME)R184DNA

4. Ecological and evolutionary processes4.1Form,functionandadaptation: From evolutionaryinnovations to bio-inspired designInvestigators from DBS: Maria Thaker,Rohini Balakrishnan, Kavita Isvaran,Vishwesha Guttal, Kartik Shanker,Renee Borges, Siddhartha Sarma,Varsha Singh, S. Mahadevan, and UtpalTatu.Co-investigators from other divisions:Rudra Pratap (CeNSE), NamrataGundiah (Mechanical Engineering),Sriram Ramaswamy (Physics), ManojVarma (CeNSE), and Tejas Murthy (CivilEngineering).Structure-Function Relationships andOptimisation in Animal Signals andSignalling BehaviourUsing termite moundsas models tounderstand biocementationAerial view of moving black buck herdInsect Ears as EcologicalAdaptations & as Modelsfor MiniatureMicrophonesFrom Bacterial Swarms to FishSchools: Decoding the Rules ofCollective Movement andApplying these to SwarmRobotics

4. Ecological and evolutionary processes4.2 Microbial ecologyInvestigators from DBS: Sumanta Bagchi,Praveen Karanth, R. Sukumar, ReneeBorges, D. N. Rao, Utpal Tatu, DipshikhaChakravortty, S. MahadevanCo-investigators from other divisions:Devanita Ghosh (Earth Sciences)Microbes in the Serviceof Mutualisms?Examining the role ofinternal microbes andmicrobial compounds inFig-Fig wasp mutualismsand in termite-producedfungicidesLinking Soil Microbe CommunityComposition with their FunctionalRoles in Carbon and Nitrogen cyclingin different Ecosystems

Number of Publications 2014-2018 (Nov.)PubMed /Web of Science/Google ScholarJournal ochemistry5764575656290Centre for Ecological Sciences3936253745182Centre for Neuroscience071316211572Microbiology and Cell Biology5250484757254Molecular Biophysics Unit6675655566327Molecular Reproduction,Development and Genetics4253432829195Total2632912542442681320

Number of Publications 2014-2018 (Nov.)PubMed /Web of Science/Google ScholarBook ochemistry-0104010309Centre for Ecological Sciences020509040020Centre for Neuroscience02----02Microbiology and Cell Biology-02-020206Molecular Biophysics Unit-0202-0610Molecular Reproduction,Development and Genetics--01030307Total041016101454

Number of Publications 2014-2018 (Nov.)PhDs istry131415142278Centre for Ecological Sciences050605040828Centre for Neuroscience--01030913Microbiology and Cell Biology121216122072Molecular Biophysics Unit161919190881Molecular Reproduction,Development and Genetics050809110437Total5159656371309

RESEARCH OUTCOMEJan 2014 TO Nov 2018S. N.Particulars123Number of Ph.D. awardedNumber of journal and (books) publicationsPatents filed/grantedJan 2014to Nov 20183091320 (54)18

Services to the Editorial boards of journalsCurrent Opinion in Structural BiologyJournal of EthologyCurrent Opinion in Insect ScienceJournal of Chemical EcologyTuberculosis

BIOLOGICAL SCIENCESAwards/honors to the serving facultyName of the Award/FellowshipNo. of RecipientsPadmashree1S. S. Bhatnagar Prize9G. N. Ramachandran Gold Medal for Excellence inBiol Sci & Technol3TWAS Fellowships5National Bioscience Career Development awards11JC Bose fellowships13INSA fellows15IAS fellows16NASI fellows13Others46

DBS Alumni over the years(partial data)OccupationNumbersPDF275Independent PI205( 50 in the US & Europe)Entrepreneur & Industry90Science Education & Journalism7Total577

Publications in Life Sciences & Medicine (2014–2018): Count, qualityand comparison with comparable Indian institutionsInstitutionIndian Institute ofScience BangaloreIndian Institute ofTechnology, BombayIndian Institute ofTechnology, DelhiIndian Institute ofTechnology, KanpurIndian Institute ofTechnology, KharagpurIndian Institute ofTechnology, MadrasTata Institute ofFundamental ResearchRatio between IISc andclosest competitorPublications Publications Publications Publications Publications Publications Publications PublicationsScholarlyin Top 25in Top 25 in Top 10 in Top 10in Top 5in Top 5in Top 1in Top ournalJournal(TotalPercentiles Percentiles Percentiles Percentiles Percentiles( Percentiles Percentiles 21.681.67#1#21.611.56Data from SciVal, QS Benchmarking

Citations/faculty in Life Sciences & Medicine:Comparison with comparable Indian institutionsInstitutionCitations perpublication(2012-2016)Citations perpublication(2014-2018)Indian Institute of Science BangaloreIndian Institute of Technology, BombayIndian Institute of Technology, DelhiIndian Institute of Technology, KanpurIndian Institute of Technology, KharagpurIndian Institute of Technology, MadrasTata Institute of Fundamental 556.3#1#2Data from SciVal, QS Benchmarking

International collaborations of DBS faculty

CENTRE FOR BRAIN RESEARCH@ IISc Kris Gopalakrishnan, cofounder of Infosys, hasgifted 225 crores forestablishment of CBR inaddition to the cost of thebuilding. CBR is an autonomouscentre of IISc. Will behoused in new buildingwithin IISc. Aging brain & Dementia How do we protect andrestore the functioning ofour brains as we age?

Major research areas at Centrefor Brain Research, IIScFaculty recruitment is going OBIOLOGYGENETICSIMAGINGCentre for Brain Research, IIScDATAANALTYTICS &DATAMANAGEMENT

Vision To evolve into a centre of advanced scientific researchand a premier centre in the international context toundertake the most challenging, high risk and large-scaleinitiatives. To provide special emphasis on interdisciplinaryresearch, scientific output (publications, patents,technology development and its transfer), humanresource development (award of Ph.D. degrees, trainingof post-doctoral fellows and project staff). To promote,-Integrated research (networking and collaborations)-Application of research findings

IIScThank You

Journal in Top 10 in Top 5 Percentiles(%) in Top 5 Percentiles in Top 1 in Top 1 Indian Institute of Science Bangalore 2345 57.2 1235 30 648 14.8 319 1.9 42 Indian Institute of Technology, Bombay 1239 52.6 574 25.1 274 12.9 141 2.1 23 Indian Institute of Technology, Delhi 1378 50 606 22.5 273 11.4 138 1.1 13 Indian Institute of Technology, Kanpur

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