ANNEXURE-IV SYLLABUS FOR WRITTEN EXAMINATION FOR

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20ANNEXURE-IVSYLLABUS FOR WRITTEN EXAMINATION FOR PAPER-I (Objective type)SUBJECT PAPER: PHARMACY/ PHARMACEUTICAL SCIENCES(DEGREE STANDARD)SUBJECT CODE: 246UNIT- I:a) The physical, physico-chemical and engineering principles governing design,layout and operation of plants for the process employed in pharmaceutical industry.b) Unit operations: size reduction, size separation, mixing, compression, filtration,centrifugation, extraction, evaporation, drying, distillation, crystallization.c) Industrial Hazards and Safety Precautions: Mechanical, Chemical, Electrical,Fire and Dust hazards, Industrial dermatitis, Accident records.d) Containers, closures and packaging materials.e) Preformulation Studiesf) Pharmaceutical excipients: Antioxidants, preservatives, Colouring, Flavouring andSweetening agents, Solvents.g) Facts related with formulation:- Physical properties, particle size. Crystal from, flowcohesiveness. Solubility. Chemical properties, Hydrolysis. Oxidation racemization,enzymatic decompositions.h) pH determination, application, buffer equation, buffer capacity, buffered isotonicsolutions; Micrometrics: Particle size determinations, derived properties ofpowders; Interfacial phenomenon : HLB values surfactants, factors influencinginterfacial phenomenon, Critical micellar concentration, Electrical properties ons,Theoriesofemulsification, multiple emulsions.i) Pharmaceutical calculations: Calculations of doses, alcohol dilutions, proof spirit,isotonic solutions.j) Nuclear Pharmacy- Introduction to Radiopharmaceuticals, radioactive half-life,units of radioactivity. Production of radiopharmaceuticals, methods of isotopictagging, preparation of radioisotopes in laboratory using radiation dosimetry level,radiation hazards, their prevention and specifications for radioactive laboratory.k) Good Manufacturing Practice.

21l) Quality control of the following formulations: Semisolids, Solid dosage forms, Liquiddosage forms, Parenteral and ophthalmic preparations.m) New Drug Delivery Systems- Aerosols, Ocusert, Transdermal Drug DeliverySystems, Osmotic Drug Delivery Systems, Targeted Drug Delivery Systems,Prolonged Drug Delivery Systems.n) Cosmetics- Dentifrices, Lipsticks, Face powders, shampoos, depilatories andManicure preparations.UNIT- II:a) Blood Products and Plasma Substitutes: Collection, processing and storage ofwhole human blood, concentrated human RBCs, dried human plasma, humanfibrinogen, human thrombin, human normal immunoglobulin, human fibrin foam,plasma substitutes, ideal requirements of PVP, dextran, etc. Control of bloodproducts as per IP.b) Basics of pharmacokinetic studies and their importancec) Pharmaceutical Biotechnology- General principles of immunology, immunologicaltechniques used in pharmacy; Sterilization of different pharmaceutical dosageforms; Sterility Testing; Methods of preparation of official sera and vaccines;Microbiological assays of antibiotics and vitamins of the pharmacopeia;Disinfectants- Classification, Mechanism and uses of disinfectants in brief. Factorsaffecting disinfection and methods of disinfectant evaluation.d) Immunologicals: Preparation and quality control of products representingvarious categories likeToxoids– Diphtheria and Tetanus LiveBacterial Vaccines– BCGKilled Bacterial Vaccines– Cholera, DPTViral Vaccines– Polio, Rabies and small poxAntitoxins– DiphtheriaUNIT – III:a) Chemistry of Alkaloids, Vitamins, Flavanoids, Glycosides, steroids, terpenes,vitamins and hormones.b) Catalytic hydrogenation, dehydrogenation, metal hydride reduction. Reductionwith hydrazine and its derivatives, Birch reduction, Clemenson‟s reduction,Meerwin – Ponndrof reduction, oxidation with periodic acid, lead tetra acetate,

22mercuric acetate and selenium oxide. Beckmann rearrangement, Schmidtrearrangement and Darzen‟s reaction.UNIT – IV:Synthesis, properties, test for purity, storage of the following categories of drugs Analgesics and Antipyretics, Anti-inflammatory, Hypnotics and sedatives, ensives, Anti-anginal, Sulphonamides,antibiotics, Anti-TB, Anti-Viral, AntiFungal, Antimalarials, Anti-Neoplastics.UNIT- V:a) Principles and Pharmacopeial Assay Procedures involving Non-aqueous xometricmethods,electrometrictitration, gravimetric analysis.b) Polarimetry and refractometry, and gasometric analysis of oils, fats and waxes.c) Chromatography- TLC, Column, Paper, GC, Ion exchange, HPLC, HPTLC, Gelelectrophoresis.d) Theory, principle, instruments and applications of colorimetry, UV- VisibleSpectrometry, Fluorimetry, Nephalometry, Turbidometry, IR, Mass, NMR, RIA.UNIT- VI:a. ion,distribution,Biotransformation and Extretion of drugs, Bioavailability and bio equivalence, Factorsaffecting bioavaliability, Mechanism of action of drugs at receptor level, adverse drugreaction.b. Drugs acting on Central Nervous system: Analgesics, Nonsteroidal anti inflammatorydrugs, Sedatives and Hypnotic, Anti convulsants and Antipsychotic drugs. Drugs usedin parkinsonism.c. Drugs acting on Autonomic Nervous system: Drugs which influence the working ofautonomic nervous system, Adrencrgic drugs (or) sympathominitic drugs, Adrenergicblocking drugs, Cholinergic drugs and cholinergic blocking drugs, Drugs acting onautonomic ganglia.d. Drug acting on cardiovasular system: cardiac glycosides, Anti hypertensive, antiarrhythmic and anti anginal drugs.e. Diuretics & anti diuretics.

23UNIT- VII:a. Drugs acting on GIT.b. Insulin and oral anti diabetic drugs, Thyroid and anti-thyroidal drugs, oralcontraceptives. Hormone replacement therapy, drugs acting on uterus.c. Antihistaminic drugs and Drugs used in Migraine.d. Chemotherapy- sulphonamides penicillins, cephalosporins, quinolones, Tetracyclines,Aminoglycosides, Chemotherapy of Tuberculosis, leprosy, malaria, cancer ,Ameobiasis, Helminthiasis.e. Toxicology- Systematic & local treatment of poisoning and their treatment.UNIT- VIII:a. General principles of cultivation and collection of drugs from wild & cultivated sources,their merits and demerits, factors affecting cultivation, adulterants and their detection.b. Plant growth regulators.c. Source, synonym, cultivation, collection, preparation for market, diagnostic characters(both macroscopical and microscopical). Constituents, substitutents, adulterants anduses of Cinnamon, Cinchona, Senna, digitalis, Clove, Saffron, Pyrethrum. Cochineal,Ergot, opium, Aloe, Acacia, Tragacanth, Benzoin, Ginseng, Brahmi, Dioscorea,Cascara, Gelatin, umbelliforous fruits, spirulina, nuxvomica, ginseng, belladonna,taxol , vinca.d. Principle and application plant tissue culture.e. Basics of fermentation technology & production of Antibiotics, Vitamins.UNIT- IX:a. Biosythetic pathways of Tropane alkaloids, Cholesterol, amino acids.b. WHO Guidelines for herbal medicines.UNIT- X:a. Drugs and Cosmetics Act 1940 and Rules 1945.b. Pharmacy Act 1948.--------

24PAPER - ISUBJECT PAPER: CLINICAL PHARMACOLOGY(POST GRADUATE DEGREE STANDARD)Objective TypeSUBJECT CODE: 352UNIT- I : GENERAL PHARMACOLOGYSources of drugs, Routes of drug administration, Dosage formulations, Pharmacokinetics,Pharmacodynamics - Good Clinical Practice& Good Manufacturing Practice - Patientcompliance, and self medication, Placebo medicines and pharmacoeconomics.Discovery and development of drugs - Preclinical studies in animals - Clinicaltrials Official regulatory guidelines.Orphan drugs and diseases, Spurious drugs, Counterfeit drugs - Pharmacoepidemiologyand Pharmacovigilance – Pharmacogenetics - Adverse drug reactions and monitoring Clinical importance of drug interactions (both pharmacokinetic and pharmaco dynamicinteractions with special reference to antibiotics, anti bacterials, NSAIDS andcardiovasculardrugs) - Therapeutic drug monitoring.UNIT - II : DRUG THERAPYIN SPECIAL SITUATIONSGeriatrics – Pediatrics - Pregnancy and Lactation.UNIT - III : CHEMOTHERAPYChemotherapy of bacterial (including Tuberculosis& Leprosy) -viral –fungal - protozoal helminthic infections - Neoplastic diseases.UNIT IV : DRUGS ACTING ON NERVOUS SYSTEM - CENTRAL NERVOUS SYSTEMGeneral anaesthetics – Narcotics – Antiepileptics - Sedatives and Hypnotics Psychopharmacological drugs - CNS Stimulants - Neurodegenerative disorders –Hallucinogens - Deaddiction for alcohol and other drugs of abuse.UNIT V : PERIPHERAL NERVOUS SYSTEM & AUTONOMIC NERVOUS SYSTEMLocal Anaesthetics -Skeletal Muscle Relaxants – Atropine & Substitutes – Adrenaline &Derivatives – Drugs in Glaucoma.UNIT VI : CARDIOVASCULAR DRUGSHypertension - Angina & Myocardial Infarction - Congestive Heart failure - Arrhythmias.

25UNIT VII : ENDOCRINOLOGYAnterior pituitary Hormones - Thyroid Hormones – Corticosteroids-Insulin & Oral Hypoglycemic drugs -Male & Female sex Hormones - Oral contraceptives - Uterine stimulants& relaxants.UNIT VIII : DRUGS ACTING ON HEMOPOEITIC SYSTEM, RENAL AND lytics&Antifibrinolytics-Antiplatelets, Hypolipidemic Drugs – Diuretics - Drugs Acting on GIT.UNIT IX : IMMUNOPHARMACOLOGY& AUTACOIDSCell and biochemical mediators involved in allergy, immuno modulation and inflammation,hypersensitivity reactions - therapeutic agents for allergy, asthma and COPD - NSAIDs &DMARDs & gout – Antihistamines - Serotonin agonists & Antagonists.UNIT X : MISCELLANEOUSVaccines - Dermatological preparations - Chelating Agents – Nutraceuticals Supplementary & formula feeds – Toxicology.*******

26PAPER - ISUBJECT PAPER: M.D.MICROBIOLOGY(POST GRADUATE DEGREE STANDARD)Objective TypeSUBJECT CODE:351UNIT – I: GENERAL MICROBIOLOGY1.2.3.4.5.6.7.History & Milestone in MicrobiologyMicroscopySterlization and disinfectionBio Safety in Microbiology LaboratoryBacterial morphologyStaining of BacteriaNutrition and growth of Bacteria8. Culture Media & Cultivation of Bacteria9. Identification of Bacteria & Bacterial Classification10. Normal Microbial flora11. Bacterial GeneticsUNIT – II: IMMUNOLOGY123456ImmunityStructures and functions of Immune systemCells of Immune SystemImmune he complement SystemAntigen - Antibody reactionsHypersensitivityAuto ImmunityHisto-Compatibility complexTransplantation ImmunityTumour ImmunityImmuno Deficiency diseasesImmuno HematologyImmuno Prophylaxis against infectious DiseasesUNIT – III: SYSTEMATIC iaCoryne bacteria

275678910BacillusMycobacteriaActinomyecetes & NocardiaColiform bacteria-Escherichia coli & kelsiella 9 ProteusSalmonellaShigella11 Yersinia12 Pasteurella & Francisella13 Haemophilus14 Bordetella15 Brucella16171819202122V. MycoplasmaMiscellaneous BacteriaUNIT - IV PARASITOLOGY1 Classification2 General principles of Diagnosing parasites & treatment of parasitic infection.3 ProtozologyPathogenic and Non-pathogenic amoebae and free living amoebaeIntestinal, Blood & Tissue flagellates Plasmodium, Toxoplasma, Isospora4 Balantidium coli5 HelminthologyCestodes, Trematodes, NematodesUNIT - V GENERAL VIROLOGY12345678Classification of virusesReplication of VirusesCultivation of VirusesIdentification of Viruses & Lab diagnosisPathogenesis & Host response to Viral infectionBacteriophageAntiviral AgentsViral VaccinesUNIT – VI: VIRUSES1 Pox2 Adeno3 Herpes

aramyxoRota genic virusMiscellaneousvirusUNIT - VII Mycology123456789Classification of fungiFungal MycotoxinsPathogenesis & Lab diagnosis of Mycotic infectionsSuperficial MycosisCutaneous MycosisSubcutaneous MycosisSystematic MycosisOpportunistic Mycosis and common lab contaminantsAntifungal AgentsUNIT- VIII Clinical Microbiology12345678910C.N.S infectionRespiratory InfectionsUrinary Tract InfectionGastro intestinal InfectionGenital Tract InfectionCongenital InfectionInfections of Eye, Ear & SkinInfections of Cardiovascular SystemP.U.OZoonotic InfectionsUNIT - IX Applied Microbiology1234567Collection ,Transport and Disposal of SpecimensEnvironmental Microbiology (Food, Water, Milk and Air)Hospital Infections Prevention & ControlMicrobial Control- anti microbial susceptibility testingBio medical waste managementBasic molecular biology related to infectionsEmerging and reemerging infections - Bio Terrorismhttps://www.freshersnow.com/syllabus/

29UNIT - X Recent Advances in Microbiology123456Advanced Molecular Techniques in Relation to Diagnosis of Infectious diseasesScope of Medical MicrobiologyAutomation in MicrobiologyAnti microbial resistance and antibiotic policyNewer VaccinesQuality Control, Audit and Accreditation of Standard Microbiology -recruitment/

30PAPER – ISUBJECT PAPER: PHARMACEUTICAL CHEMISTRY (DEGREE STANDARD)Objective TypeSUBJECT CODE.245UNIT I1) Atomic structure and valency, Radioactivity, Radio isotopes and Pharmaceuticalapplications of Radio Pharmaceuticals, hazards and precautions.2) Sources of impurities in Pharmaceutical substances; Limit test as per I.P;Fundamentals of volumetric Analysis.3) A systematic study of inorganic compounds for their preparation, assay and usewhich includes Gastrointestinal agents, Topical agents and Dental products.UNIT II1)2)3)Assay, test for purity of sodium, calcium, iron, aluminium and ammoniumcompounds. Major intracellular and extra cellular electrolytes.Preparation and use of Chemical reagents and Volumetric Solutions as perPharmacopia in Pharmaceutical Analysis.Theory of Co-ordination Compounds with special reference to application inPharmaceutical Analysis via EDTA, Dimercaprol, Pencillamine.UNIT III1)2)3)Physiochemical properties of gases, liquids and solids. Density, Surface tension,Viscosity and physical properties.Osmosis, osmotic pressure, vapour pressure, Raoult's law, Ostwalds dilution law,Molecular weight determination by osmotic pressure.Non- aqueous and complexometric titrations, analysis of fats, oils and waxes.Importance of quality control, Different types of titrations, Gasometric analysis anddetermination of Nitrogen.UNIT IV1) Gases in liquids, liquids in liquids, partially miscible, completely miscible andcompletely immiscible liquids.2) Thermochemistry: Heat of reaction, heat of solution, heat of formation and heatof neutralization and Hess law.3) Stereo chemistry, optical isomerism, Geometrical isomerism.4) Theory of Polarimetry, Refractometry and catalyst.UNIT V1) Electronic configuration and electron displacement effects, chemical bonds andpolarity.2) Chemistry and medicinal uses of cardiac glycosides and vitamins.3) Synthetic utility of acetoacetic ester, Grignard reagent andDiazonium compounds.

31UNIT VI1) Aromaticity,concept of resonance, Nucleophilic, Electrophilicsubstitution reaction, Elimination reactions in aliphatic and aromaticcompounds.2) Anti-infective agents comprising of Anti-fungal agents, synthetic antibacterialagents, anti-tubercular Agents, and Anthelmintics agents.UNIT VIIChemical structure, Synthesis, assay and therapeutic uses of organic synthetic drugslike, Antidepressants, General anesthetics, Sedatives and hypnotics, Narcoticanalgesics, Anti -histaminics, Antimalarials., Sulphonamides, Drugs acting on CVS.UNIT VIII1) Structural elucidation of natural products - General methods.2) Structure, chemistry, methods of estimation, and uses of Alkaloids, Carbohydrates,and Proteins.3) Chemistry of steroids and natural hormones, currently used steroidal drugs.UNIT IX1) Study of separations and determination involving TLC, HPTLC, and columnchromatography.2) Colorimetry, UV and Visible Spectrophotometry, Spectrofluorimetry-Theory,Principle, Instrumentation and working.3) Theory and principles of separation techniques involving Ultra centrifugation, HPLCand Gel filtration.UNIT X1) Conductometry, Potentiometry and Amperometric titrations, Basic conceptsand application in pharmaceutical analysis.2) Radio Immuno Assay and Electrophoresis.3) Theory, Principle and application of NMR, MS, IR spectroscopy.*******

32PAPER – ISUBJECT PAPER: CHEMISTRY (DEGREE STANDARD)Objective TypeSUBJECT CODE.243UNIT - IPHYSICAL CHEMISTRY:a) Gas law and Kinetic Theory:- Ideal gas equation - Deviation from ideal behaviour vander waals equation for real gases - Molecular velocities - the Maxwell's distributionof molecular velocities –heat capacity and viscosity of gases.b) Solid State:- Crystal systems - Bravaislattice - Unit Cell - Miller Indices - Symmetryelements in crystals - Bragg's equation - Radius ratio's and packing in crystals –Determination of crystal structures by Braggs method – structure of Nacl, Kcl, Znsand spinals.c) Thermodynamics:- Intensive and extensive variables - First law ofthermodynamics – CP and CV relation - Hess's law of constant heat summation Kirchoff's equation - Second law of thermodynamics - Carnot theorem - entropy andprobability, Joule Thomson effect -Free energy and Chemical equilibrium Temperature and pressure dependence and - Gibb's and Helmholtz functions –Heterogeneous equilibrium and Le – Chatlier principle.UNIT – IId) Chemical Kinetics:- Rate laws - rate constant - order and molecularity of reactionsI, II, III, and Zero order reaction Arrhenius theory - collision theory and Transition statetheory - catalysis.e) Electro-Chemistry:- Types of reversible electrodes - Nernst equation - referenceelectrode and standard hydrogen electrode - computation of cell e.m.f. calculations ofthermodynamic quantities of cell reactions (DG, DH, DS and K) - Over potential andhydrogen over voltage - Arrhenius theory - Debye 'Huckel equation - Kohliraush's law- Ostwald's dilution law - Determination of PH and Pka of acids by potentiometricmethods.UNIT – IIIf) Chemical spectroscopy:- Elementary ideas of microwave, infrared, Raman, uv,NMR, ESR and Mass spectroscopy.g) Pharmaceutical chemistry: Terminology pharmacology, pharmacotheraies,toxicology, chemotherapy, classification, and nomenclature of drugs, sources ofdrugs, assay ofdrugs by biological, chemical and immunological methods,physiological effects of functional groups of drugs different types of drugs likeanalgesics, antibiotics, antiseptics, disinfectants, anesthetics, antidepressants,antipsychotic etc.

33UNIT - IVh) Colloids and surface Chemistry:- Classification – preparation, purification properties - Tyndall effect- Gels - Emulsions Absorption - Langmuir isotherms Heterogeneous catalysis.i) Physical properties and Chemical constitution:- Surface tension - parachor and itsapplication to structural problems – Dipole moment - applications of dipolemomentmeasurements to structural studies of simple inorganic and organic molecules magnetic properties of matter, diamagnetism, paramagnetism, ferromagnetism andanti- ferromagnetism - Applications to structural problems.UNIT - VINORGANIC CHEMISTRY:j) Periodic classification:- Classification based on electronic configuration - periodicproperties - atomic and ionic radii, ionisation potential, electron affinity andelectronegativity- various scales - trend along periods and groups.k) Chemical bond:- Lattice energy - VSEPR Theory and its applications - partial ioniccharacter from electronegativity - Fajan's Rules.l) Compounds of Boron:- Electron deficient nature of boron compounds preparation and properties of halides and nitrates of boron - diborane – Borazine,silicones and structures of silicatesUNIT - VILANTHANIDES AND ACTINIDES:m) Ocurrence Electronic configuration oxidation state, magnetic properties andcomplexation behaviour - comparison of lanthanides and actinides, lanthanidecontraction and their position in the periodic table.n) Fertilisers:- Ammonium nitrate, ammonium phosphate, Superphosphate andDiammonium Phosphate, NPK fertilisers.o) Nuclear Chemistry:- Radio activity – detection and measurement – half life period- Nuclear stability, - n/p ratio - isotopes, isobars and isotones Nuclear reactionsSpallation - Nuclear fission and fusion – stellar energy uses of nuclear energy nuclear power projects in India - applications of tracers in industry, medicine,agriculture.UNIT - VIIp) Co-ordination Chemistry:- Redo Nomenclature - theories of co-ordinationcompounds - Werner, valence bond, crystal field and ligand field theories - Effectiveatomic number - isomerism - Metal Carbonyls of iron and Nickel.q) Analytical Chemistry:- i) Principles of volumetric analysis - different types oftitrations gravimetric analysis - separation and purification techniques.

34UNIT - VIIIORGANIC CHEMISTRY:r) Types of reactions:- Nucleophilic, electrophilic, free radicals, addition andelimination reactions.s) Electron displacement effects:- Inductive, inductometric, electromeric, mesomeric,resonance, hyperconjugation and steric effects.UNIT - IXt) Nature of Bonding:- Hybridisation (Sp, Sp2 & Sp3) and Geometry of molecule cleavage of bonds - homolytic and heterolytic fission of carbon – carbon bonds Reaction intermediates - free radicals, carbocations and carbonions - their stability.u) Stereo Chemistry:- Optical isomerism and Geometrical isomerism - chirality optical isomerism of lactic and tartaric acid - Racemisation - Resolution - Asymmetricsynthesis - walden inversion - cis and trans isomerism of maleic and fumeric acids R-S-Notations - conformational analysis of cyclohexane - applications of ORD andCD Techniques.UNIT - Xv) Dyes:- Classification and Properties of dyes – methyl orange, cangored, malachitegreen, fluorenscein and indigo.w) Carbon hydrates:- Classification and reactions - Glucose, Fructose, Sucrose andlactose- structure of glucose and fructose.x) Aromatic Substitution:- Mechanism of nitration, Halogenation, sulphoration and FriedelCrafts reaction - Orientation effects - nucleophilic substitution - Benzyne mechanism.******

35PAPER-IIGENERAL STUDIES (DEGREE STANDARD)Objective TypeSUBJECT CODE : 003UNIT-I: GENERAL SCIENCEPhysics Universe-General Scientific laws-Scientific instruments-Inventions and discoveriesNational scientific laboratories-Science glossary-Mechanics and properties of matter-Physicalquantities, standards and units-Force, motion and energy-Electricity and Magnetism, Electronicsand Communication -Heat, light and sound-Atomic and nuclear physics-Solid State Physics –Spectroscopy- Geophysics - Astronomy and space science.Chemistry Elements and Compounds-Acids, bases and salts-Oxidation and reduction-Chemistryof ores and metals-Carbon, nitrogen and their compounds-Fertilizers, pesticides, insecticidesBiochemistry and biotechnology-Electrochemistry-Polymers and plastics.Botany Main Concepts of life science-The cell-basic unit of life-Classification of living organismNutrition and dietetics-Respiration-Excretion of metabolic waste-Bio-communication.Zoology Blood and blood circulation-Endocrine system-Reproductive system-Genetics thescience of heredity-Environment, ecology, health and hygiene, Bio- diversity and its conservationHuman diseases-Communicable diseases and non- communicable diseases- prevention andremedies- Alcoholism and drug abuse-Animals, plants and human lifeUNIT- II: CURRENT EVENTSHistory Latest diary of events – National--National symbols-Profile of States-Defence, nationalsecurity and terrorism-World organizations-pacts and summits-Eminent persons & places in newsSports & games-Books & authors -Awards & honours-Cultural panorama-Latest historical events India and its neighbours - Latest terminology- Appointments-who is who?Political Science 1. India‟s foreign policy 2. Latest court verdicts – public opinion 3. Problems inconduct of public elections 4. Political parties and political system in India 5. Public awareness &General administration 6. Role of Voluntary organizations & Govt., 7. Welfare oriented govt.schemes, their utilityGeography Geographical landmarks-Policy on environment and ecologyEconomics Current socio-economic problems-New economic policy & govt. sectorScience Latest inventions on science & technology-Latest discoveries in Health Science-Massmedia & communicationUNIT-III : GEOGRAPHYEarth and Universe - Solar system-Atmosphere hydrosphere, lithosphere - Monsoon, rainfall,weather and climate - Water resources - rivers in India-Soil, minerals & natural resources - Naturalvegetation - Forest & wildlife-Agricultural pattern, livestock & fisheries -Transport includingSurface transport & communication - Social geography – population -density and distributionNatural calamities – disaster management-Climate change - impact and consequences mitigation measures - Pollution Control.

36UNIT-IV: HISTORY AND CULTURE OF INDIAPre-historic events -Indus valley civilization-Vedic, Aryan and Sangam age-Maurya dynastyBuddhism and Jainism-Guptas, Delhi Sultans, Mughals and Marathas-Age of Vijayanagaram andthe bahmanis-South Indian history - Culture and Heritage of Tamil people-Advent of Europeaninvasion-Expansion and consolidation of British rule - Effect of British rule on socio-economicfactors-Social reforms and religious movements - India since independence-Characteristics ofIndian culture-Unity in diversity – race, colour, language, custom-India-as secular stateOrganizations for fine arts, dance, drama, music-Growth of rationalist, Dravidian movement in TNPolitical parties and populist schemes- Prominent personalities in the various spheres – Arts,Science, literature and Philosophy – Mother Teresa, Swami Vivekananda, Pandit Ravishankar ,M.S.Subbulakshmi, Rukmani Arundel and J.Krishnamoorthy etc.UNIT-V: INDIAN POLITYConstitution of India - Preamble to the constitution- Salient features of constitution- Union, Stateand territory- Citizenship-rights amend duties- Fundamental rights- Fundamental duties- Humanrights charter- Union legislature – Parliament- State executive- State Legislature – assemblyStatus of Jammu & Kashmir- Local government – panchayat raj – Tamil Nadu- Judiciary in India –Rule of law/Due process of law- Indian federalism – center – state relations-. Emergencyprovisions- Civil services in India- Administrative challenges in a welfare state- Complexities ofdistrict administration- Elections - Election Commission Union and State. Official language andSchedule-VIII- Amendments to constitution- Schedules to constitution-. Administrative reforms &tribunals- Corruption in public life- Anti-corruption measures – Central Vigilance Commission, lokadalats, Ombudsman, - Comptroller and Auditor General of India- Right to information - Centraland State Commission- Empowerment of women- Voluntary organizations and public grievancesRedressal- Consumer protection formsUNIT- VI: INDIAN ECONOMYNature of Indian economy-Need for economic planning-Five-year plan models-an assessmentLand reforms & agriculture-Application of science in agriculture Industrial growth-Capital formationand investment-Role of public sector & disinvestment-Development of infrastructure- Nationalincome- Public finance & fiscal policy- Price policy & public distribution- Banking, money &monetary policy- Role of Foreign Direct Investment (FDI)- WTO-globalization & privatizationRural welfare oriented programmes- Social sector problems – population, education, health,employment, poverty-HRD – sustainable economic growth- Economic trends in Tamil Nadu Energy Different sources and development- Finance Commission -Planning CommissionNational Development CouncilUNIT-VII: INDIAN NATIONAL MOVEMENTNational renaissance-Early uprising against British rule-1857 Revolt- Indian National CongressEmergence of national leaders-Gandhi, Nehru, Tagore, Nethaji -Growth of militant movements Different modes of agitations-Era of different Acts & Pacts-World war & final phase struggleCommunalism led to partition-Role of Tamil Nadu in freedom struggle - Rajaji, VOC, Periyar,Bharathiar & Others-Birth of political parties /political system in India since independence.

37UNIT-VIII: APTITUDE AND MENTAL ABILITY TESTSConversi on of information to data-Collection, compilation and presentation of data - Tables,graphs, diagrams-Parametric representation of data-Analytical interpretation of data Simplification-Percentage-Highest Common Factor (HCF)-Lowest Common Multiple (LCM)-Ratioand Proportion-Simple interest-Compound interest-Area-Volume-Time and Work-Behaviouralability -Basic terms, Communications in information technology-Application of Information andCommunication Technology (ICT)- Decision making and problem solving-Logical Diagrammatic Sequences.******

b. Drugs acting on Central Nervous system: Analgesics, Nonsteroidal anti inflammatory drugs, Sedatives and Hypnotic, Anti convulsants and Antipsychotic drugs. Drugs used in parkinsonism. c. Drugs acting on Autonomic Nervous system: Drugs which influence the working of autonomic nervous system, Adrencrgic drugs

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