Message From The Department Head

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Fall 2020Department of Psychiatry NewsletterCalgary ZoneMessage from the Department HeadDr. Valerie TaylorThank you everyone for everything you have done during 2020. As we look in to 2021, Ithink many of us are hoping to finally see a littlestability start to occur. Our Department has beenvery resilient as we adapt to working from home, virtualcare, COVID protocols, staffing changes and adapting toincreased volumes and challenging resources. Our goal asa Department is to focus on ensuring you continue to beupdated and informed, and to be a source of accurateinformation. With the support of Dr. Hashman and theSite Leads, we are now producing a monthly newsletter inaddition to our quarterly updates, so we can share acrossall sites the activities occurring at each hospital, as wellchallenges and successes. This way we ensure that we areat least all informed of everything that is occurring. Wealso need to share successes and I think this is a good wayto do it – there are a lot of great things happening and we are doing great work with our clinicalinitiates and nimbleness. Our academic impact continues to grow as well, as we continue torecruit excellent academic colleagues to Calgary.Stay safe everyone.Best,Valerie

Fall 2020Department of Psychiatry NewsletterCalgary ZoneDepartment of Psychiatry UpdatesIjust wanted to thank you all for your support. The run was a great success and raised nearly 200,000! We also had almost the same number of participants as previous years. Prettygood for a global pandemic and economic downturn with oil prices!Lisa GagnonPsychiatristQuality AssurancePerinatal Mental Health Network ChairMental Health Clinical Trials Unit (MHCTU)Thomas J Raedler, MDMedical Director, Mental Health Clinical Trials Unit (MHCTU)The Mental Health Clinical Trials Unit(MHCTU) continues to pursue thegoal of finding new and betterpharmacological and interventionaltreatments for psychiatric disorders. Ourcurrent clinical trials cover the areas ofschizophrenia, attenuated psychosissyndrome (prodromal psychosis) andADHD. Participating in clinical trials offersparticipants the opportunity of receivingtreatment with novel pharmaceuticalcompounds that are not yet commerciallyavailable as well as frequent assessmentsand oversight of care. Please be aware thatmany participants experience animprovement in their symptoms whileparticipating in a clinical trial. We continueto rely on your ongoing support for ourclinical trials.Like many other programs, our activitieswere significantly impacted by COVID-19.All clinical trials were closed for furtherrecruitment. We were able to use onlineassessments for subjects who were alreadyenrolled in our trials. We are slowly startingto re-open our clinical trials to recruitmentand screening and resume activities inkeeping with the COVID-19 safetyparameters.The MHCTU is currently participating inthe following clinical trials:BI Cognition Study in Schizophrenia 13460038 (NCT03859973):BI 425809 is an orally administered glycinetransporter-1 inhibitor. This phase II clinicaltrial assesses whether treatment with thiscompound, in combination with regularcomputerized cognitive training, helps toimprove cognition in schizophrenia.Real World Evidence of the Efficacy andSafety of FOQUEST (reFOQus)(NCT04152629):This Phase IV open-label clinical trialcompares the efficacy and safety ofmethylphenidate (Foquest) andlisdexamfetamine (Vyvanse) in children,2 Page

Fall 2020Department of Psychiatry NewsletterCalgary Zoneadolescents and adults with ADHD. Dr.Ortega serves as Principal Investigator andDr. Binder and Dr. Chang are CoInvestigators.NaBen Studies:NaBen (sodium benzoate) is alreadyapproved as a food additive (E211). Thiscompound is being tested in clinical trials asit is thought to improve the function of theNMDA-receptor. Previous studies haveshown excellent efficacy and safety forNaBen in improving symptoms ofschizophrenia.The NaBen Adolescent SchizophreniaStudy (Adaptive Phase II Study to Evaluatethe Safety & Efficacy of Sodium Benzoateas an Add-on Treatment for Schizophreniain Adolescents; NCT01908192) assesses theeffects of sodium benzoate as an add-onmedication to ongoing antipsychotictreatment on symptoms of schizophrenia inadolescents with schizophrenia between theages of 12 and 17 years.The NaBen Adult Schizophrenia Study(Study to Evaluate Safety & Efficacy ofNaBen as Add-on Treatment forSchizophrenia in Adults; NCT02261519)assesses the effects of add-on treatment withsodium benzoate in adults withschizophrenia, who continue to struggle withpsychotic symptoms despite ongoingantipsychotic treatment.The NaBen Clozapine study (An AdaptivePhase II/III, Two-Part, Double-Blind,Randomized, Placebo-controlled, DoseFinding, Multi-center Study of the Safetyand Efficacy of NaBen , as an Add-onTherapy With Clozapine, for ResidualSymptoms of Refractory Schizophrenia inAdults; NCT03094429) assesses sodiumbenzoate as add-on treatment in subjectswho failed to experience sufficient benefitsfrom treatment with clozapine.BI409306 Studies:BI409306 is a novel PDE9-Inhibitor(Phosphodiesterase–9 Inhibitor). Thiscompound increases concentrations ofsecond messenger in neurons. Whileinteracting with the glutamatergic system,this compound is also thought to improvesynaptic plasticity. In a previous clinicaltrial that we also participated in, thiscompound was very well tolerated but failedto show significant improvement in the areaof cognitive impairment associated withschizophrenia (CIAS).The BI relapse prevention Study (A phaseII randomised, double-blind, placebocontrolled study to evaluate the efficacy,safety, and tolerability of orallyadministered BI 409306 during a 28-weektreatment period as adjunctive therapy toantipsychotic treatment for the prevention ofrelapse in patients with schizophrenia;NCT03351244) assesses if the addition ofBI 409306 to ongoing antipsychotictreatment helps to prevent relapses in adultswith schizophrenia. This clinical trial wasrecently terminated by the sponsor.The BI Attenuated Psychosis SyndromeStudy (A phase II randomized, doubleblind, placebo-controlled study to evaluatethe efficacy, safety, and tolerability of orallyadministered BI 409306 during a 52-weektreatment period as an early intervention inpatients with attenuated psychosissyndrome; NCT03230097) assesses if BI409306 can prevent subjects, who are athigh risk of developing psychosis, frombecoming worse.3 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneWe continue to rely on your support for ourclinical trials program. You can obtainadditional information on our current studiesby accessing our web-site. Please feel free tocontact myself (Thomas.raedler@ahs.ca),Geri Anderson (phone 403.210.6903 oremail Geri.Anderson@ahs.ca) or Jeff Cheng(phone 403.210.8679 or emailcfj.cheng@ucalgary.ca) if you wish to havemore information about one of these studies,or if you wish to refer a patient for possibleparticipation.The Child and Adolescent Addiction, Mental Health and PsychiatryProgram (CAAMHPP)Jennifer Kuntz MSW, RSWAdverse Childhood Experiences (ACE) & Trauma Informed Care (TIC) Project FacilitatorChild and Adolescent Addiction, Mental Health & Psychiatry Program CAAMHPP – CalgaryZoneThe Child and Adolescent Addiction,Mental Health and PsychiatryProgram (CAAMHPP) is advancingthe Adverse Childhood ExperiencesACE/Trauma Informed Care TIC into phaseII focusing on Resilience. This phase of theinitiative aligns with larger system prioritiesincluding the CAAMHPP Strategic Plan2016-2021, the Addiction and Mental HealthReview, Alberta Health Services TraumaInformed Care Project, research on theimpact of toxic stress on the developingbrain and the science of resilience.Our mission is to provide world class mentalhealth and addiction services from a traumaresponsive lens that optimizes the health andwell-being of children, youth and theirfamilies. Our goal is to expand on thefoundational work completed in phase I, inthe area of clinical practice, service deliveryand translational research & evaluation. Inphase I, we successfully implemented thesystematic collection and documentation ofACE scores for all clients resulting in over10,000 scores being collected over the past 5years. The data has shown a stabledistribution of ACE scores over the last 5year period revealing that 1/3rd ofCAAMHPP clients have an ACE score of 4or higher and 1/10th of CAAMHPP clientshaving an ACE score between 7-10.For more information on this initiativeplease feel free to connect with JenniferKuntz, Resilience 2.0 Initiative ProjectFacilitator @ Jennifer.Kuntz@ahs.ca.4 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneAs trauma and adversity continue to impact a large majority of CAAMHPP clients, wehave committed to phase II, Resilience 2.0, focusing on the following areas:bolstering client/family resilience through skill development/external supports,decreasing the burden of adversity and increase protective factors;intervening early to change the trajectory of ACE/trauma accumulation in earlychildhood;evaluating trauma interventions to see what works, with who and when (frequency,intensity, dosing, timing);creating, evaluating and scaling up clinical pathways and interventions for thispopulation and;continuing knowledge translation and staff professional development to buildoverall trauma competence and;strengthening our partnerships within Addiction & Mental Health as well as withother organizations/agencies who are also engaged in this work.A&MH Trauma Advisory Committee UpdateJennifer Kuntz & Dr. Diana Czechowsky - Co-Chairs Trauma Advisory CommitteeAs we work towards becoming atrauma informed organization, theA&MH Trauma AdvisoryCommittee has expanded to includemembers from across the entire portfolioincluding child and adolescent through togeriatric mental health and addiction. Thework is focused around the following threegoals:5 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneGOAL 1To ensure that all staffworking within CalgaryZone’s A&MH services aretrauma-informed.GOAL 2To ensure that relevantclinical staff working withinCalgary Zone’s A&MHservices are traumacompetent.GOAL 3To ensure that relevant clinical staffworking within Calgary Zone’sA&MH services have the supportrequired to provide evidence-basedtrauma-focused treatment to clientsthat require such treatment.The committee is developing educational &training opportunities as well as resourcesfor all A&MH staff to meet these goals. Asa starting point, the committee recommendsthat all A&MH staff watch the TraumaInformed Care Module available on MyLearning Link, to strengthen the collectivetrauma literacy across all A&MH staff(admin, clinical, leadership).The committee is also exploring varioustraining/educational opportunities toincrease trauma competency across A&MHincluding trauma focused intervention.The Trauma Advisory Committee willprovide updates regarding theseopportunities in the upcoming months.6 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneUndergraduate Medical Education (UME) ProgramDr. Tim Ayas MD FRCPC CCFP MPH BScClinical Assistant Professor, U of CSection Chief Community, Addictions, & Rural SouthClerkship Director, Department of Psychiatry, U of C, UMEt’s been an exciting and tumultuous yearto say the least. With the onset of thepandemic, I know many students in theClass of 2021 were concerned they may notbe able to complete on time to start theircareers. Thanks to the hard work of theAssistant Dean Dr. Kevin Busche, the hardworking staff at the office of the UME, andall the psychiatry clerkship staff includingDr. Nancy Brager, Clerkship Site Directors,site administrators, residents, and preceptorsthese clerks will finish on time to start theirrespective residencies in July. A number ofadjustments to clerkship had to be conductedto achieve this potential goal: utilization ofthe time off clinical work at the onset of thepandemic to complete all the academicIcommitments from each Department(usually reserved for academic half dayslongitudinally), re-routing of medicalstudents from outbreak sites (at times withlittle notice), and acceptance of a shortenedrotation by many faculties. The studentstruly appreciate the efforts made, and I wantto send a sincere thank you to all of you whohave assisted in this process. Yourflexibility to the adaptations to the logisticalmanner we deliver clerkship is noted andappreciated. Please consider attending ourannual virtual retreat on November 6th,2020 to learn more about how you can bemore involved in this robust clerkshipprogram.Post Graduate Medical EducationDr. Greg Montgomery/Pauline BurgessEven with all the challenges over thelast seven months, the residencyprogram has continued to operateamazingly well in no small part due to thetenacity of our residents and faculty toprovide the best possible experience amidsttumultuous circumstances.As many of you are aware, RCPSCpostponed certifying exams for the final yearresidents from the spring, re-instituting themin the summer. As of October 1, we arehappy to report that all 10 examineesreceived the good news of their success.Our congratulations to Suzanne Black, MarkColijn, Andrew Dutcher, Darby Ewashina,Erin Girard, Beata Komieriowski, PatriciaMaron, Sara Meunier, Ashley Pauls andAleena Shariff.Psychiatry across Canada launchedCompetency by Design (CBD) in July 2020.7 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneFor our program, we created eight – 2 weekblocks of placements in areas that wouldallow PGY-1s to achieve objective for theEntrustable Professional Acts (EPAs)focusing on the basic skills of obtaining apsychiatric history and communicatingclinical encounters. With a big thanks toInpatients across all adult sites, PsychiatryEmergency at FMC, RGH and the CSU, allof our PGY-1s were successful incompleting the first stage of CBD known asTransition to Discipline (TTD).In terms of infrastructure for CPD, Dr.Selmer recruited Dr. Crockford to chair theCompetence Committee, consisting of Drs.Beck, Birkett, deGroot, Mohan, Ortega andRaiche. Members provided a review of eachPGY-1s Workplace Based Assessments(WBAs) that lead to meeting therequirements of the two EPAs. The second“team” in CBD is the group of academicadvisors who meet regularily with theirdesignated resident to review progress inachieving EPAs as they move throughtraining. This is a vital and welcomedaddition that supports the residents on a oneto-one basis. We welcome and thank thefollowing eight staff who have taken on thisrole; Drs. Finkbeiner, Jalali, Mackie,McLane, Ratti, Scott, Tan and Weatherbee.To address the lost time in the early stagesof the pandemic, in preparing for thecertifying STACERs, we are happy to reportthat Dr. Philp Stokes will join Dr. UrsulaHines in working with our PGY-4s startingin January. This ongoing support in honingthe interview skills over the last decade havebeen extremely invaluable and we trulyappreciate all the work Dr. Hines andformerly Dr. Fawcett have devoted to thiseffort.In order to provide residents with a broaderunderstanding of cultural psychiatry and itsimplications on patient care, this fall, allPGY-2-5s have completed a half-dayworkshop created and hosted by Dr. RachelGrimminck and PGY-4 Dr. Harry Zhou.This was an extensive undertaking and wewant to thank them for all the behind thescenes work that these workshops entailed.Nationally, CaRMS interviews will be heldvirtually March 8-28, 2021. In order toprovide applicants with opportunities tointeract and learn about our program, theresidents created an excellent videohighlighting the program: a link can befound on the department website. Inaddition, residents are hosting at least 4different Zoom sessions for interestedstudents across Canada to “meet” residentsand ask questions. A very big thanks toTaka Hoy, Hilary Aadland and Jian Choofor the work in creating the video, as well asorganizing the town hall sessions.As you can surmise, the residency programhas not been slowed down by the pandemic.There were resident redeployments but allchanges to affected residents did not hampermeeting core training requirements. A bigthank you to all who had to pivot in order tomake the changes work; resourcefulness istruly a valuable quality!8 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneContinuing Professional Development (CPD)Dr. Thomas Raedler/Anne Endershe multi-disciplinary departmentalCPD committee oversees all CPDactivities through our department.We meet on the second Monday of eachmonth for one hour. We are always lookingfor new members for our committee. Pleaselet us know if you are interested in joiningour team.TFor the Spring 2020 Grand Rounds semesterwe awarded a total of 452 CME credits to 81participating physicians. The CMEcertificates for the Spring 2020 GrandRounds semester were sent out on July 14,2020 to all physicians who completed theweekly online survey. Please let Anne knowif you did not receive your CME-certificate.The last months were unprecedented due tothe sudden surge of COVID-19, whichresulted in an abrupt end to all face-to-faceactivities in mid-March. Thanks to theefforts of the members of our department,we were able to continue most of our CPDactivities, albeit in a very different way. Aspecial thank you goes to Anne Enders, whoquickly familiarized herself with Zoom andwho has been coordinating all our onlineactivities. Still, we are looking forward tothe time when we will be able to resume ourregular Grand Rounds in G500.The Fall 2020 Grand Rounds semesterstarted on September 8th with a beautifultribute honouring Dr. Glenda MacQueen. Atthis time, all Fall 2020 Grand Rounds arescheduled to continue via Zoom only. Thezoom link will be included in our weeklyGrand Rounds email reminder.The Spring 2020 Grand Rounds semesterfinished on June 23, 2020. As with mostevents, COVID-19 disrupted our schedule.We were able to adapt quickly and switchedour schedule to presentations with a focuson COVID-19. We also switched our GrandRounds presentations to Zoom, whichworked out surprisingly well. Thank you tothose who volunteered on such short noticeto ensure Grand Rounds continued. Thanksto everyone’s efforts, we only had to cancelfive Grand Rounds presentations.The ‘Psychiatry Quarterly Updates (PQU)’are three-hour sessions that focus on aspecific topic. Physicians can earn up to3.75 Section 3 CME-credits. The next PQUsessions are scheduled for September 25,2020 (Obsessive Compulsive Disorder) andDecember 4, 2020 (Neuropsychiatry).Registration is through the Office ofContinuing Medical Education andProfessional Development of the CummingSchool of Medicine. We always welcomesuggestions of topics.Dr. Thomas Raedler chaired the 2020Psychiatry Online Literature Review Course(POLRC). POLRC covered 12 journalarticles with a focus on ‘Highlights of 2019’and took place from February 24, 2020 untilJune 30, 2020. The POLRC offers the optionof obtaining up 38.0 MOC Section 1 and 3.09 Page

Fall 2020Department of Psychiatry NewsletterCalgary ZoneMOC Section 3 Self-Assessment hours fromthe convenience of home. This year we had45 participants.Please notify Anne Enders atmargaret.enders@ucalgary.ca if you are notreceiving our weekly email updates. Forphysicians, please let Anne Enders know ifyou are not receiving the weekly onlinesurveys (your CME-credits will be based onthe completion of this online survey).Thank you again for your ongoing supportof our CPD-activities.Mathison Centre UpdatesDr. Paul Arnold/ Josephine AddaMathison Centre researchers takeschool based mental healthresearch a notch furtherCoping at school during the pandemic Dr. Kelly Schwartz, member of theMathison Centre and Associate Professor atthe Werklund School of Education is leadinga research study to gauge the mental healthof school-aged children as they return toschool in the midst of the COVID-19pandemic. The all Mathison-Centre teamincludes Drs. Carly McMorris,

Department of Psychiatry Newsletter Calgary Zone 2 P a g e Department of Psychiatry Updates just wanted to thank you all for your support. The run was a great success and raised nearly 200,000! We also had almost the same number of participants as previous years. Pretty good for a global pandemic and economic downturn with oil prices! Lisa .

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