How To Report: For Laboratories - Tennessee
How to Report: For LaboratoriesResponsibility to ReportAll healthcare providers (inpatient or outpatient), laboratories, or other persons knowing of orsuspecting a reportable disease case are responsible for reporting it to the health department.Laboratories in healthcare facilities should refer to the information below. Healthcare providersand laboratories in the same healthcare facility both have a duty to report.Reporting GuidanceThe diseases, events, and conditions reportable to Tennessee Department of Health (TDH) bylaboratories for 2018, including laboratories in healthcare facilities, are provided in the 2018 List ofReportable Diseases in Tennessee: For Laboratories (page 2 of the List). The Detailed LaboratoryGuidance document provides additional details regarding the reportable tests, results, andspecimen sources, and specimen/isolate requirements for submission to the State Public HealthLaboratory. The State Public Health Laboratory provides additional details about submission ab.html.Reporting Methods and RequirementsLaboratories should report using one of the following methods:1. Electronic Laboratory Reporting (ELR)Requirements for electronic laboratory reporting are available ting.html.2. Printed laboratory reportThe information below is required for printed laboratory reports, if available.(1) Patient demographics (including patient date of birth, address, sex, race, ethnicity, andtelephone)(2) Ordering provider and facility name, phone number, address(3) Performing laboratory name, phone number, and address(4) Reporting facility name, phone number, address(5) Date of the laboratory report(6) Test performed (may differ from the test ordered)(7) Accession number(8) Specimen type/source and collection date(9) Result (quantitative and qualitative), interpretation, and reference rangeIf the printed laboratory report does not include the required information listed above, then thePH-1600 should be completed for the missing information and submitted with the printedlaboratory report. The PH-1600 is the general reporting form for most diseases, events, orconditions when reporting to public health (see below for special reporting). Laboratories are notrequired to report information in the Clinical Information section of the PH-1600.Laboratory reports and any necessary reporting forms may be faxed to the Communicable andEnvironmental Diseases and Emergency Preparedness (CEDEP) Division at (615) 741-3857. To faxdirectly to the local or regional health office, refer to ldepartments.html. Laboratories may also report online ex.php?s XTJTN4MD3D, where the PH-1600 may becompleted and an electronic version of the paper laboratory report attached.Reporting TimeframeRefer to the List for the reporting timeframe for each condition. Most of the reportable diseases,events, or conditions require reporting within one week via the methods described above. The
next business day and immediately reportable diseases, events, and conditions require a telephonecall to the health department (refer to the List icons). Refer to the Detailed Laboratory Guidancefor catchment limitations for the HAI Emerging Infections Program (EIP) conditions. For questions,contact CEDEP at (615) 741-7247 or (800) 404-3006.Special ReportingFor blood lead levels, healthcare providers and laboratories are required to report blood lead testresults 5μg/dl in 1 week and 5 μg/dl in 1 month. Reports should include a minimum of thePatient's First and Last Name, Date of Birth, Gender, Race, Ethnicity, Address (Street Address, City,State, Zip Code and County of Residence); Sample Date, Sample Type; Provider's Name, Provider'sPhone Number and Payment Source. Reports should be made online athttps://leadinput.tennessee.edu/leadin/. For more information, refer ch-lead/for-providers.html.Healthcare-associated infections reported for the Emerging Infections Program (EIP), should bereported according to the guidelines in the Detailed Laboratory Guidance document. Anyquestions can be sent to HAI.Health@tn.gov.HIPAA Disclaimer for the PH-1600 FormThis form contains information that is Protected Health Information as defined by the Privacy Ruleof the Health Insurance Portability and Accountability Act of 1996 (HIPAA) and, when prepared by aHIPAA Covered Entity, should be prepared, processed, stored, and transmitted with appropriatesafeguards against unlawful disclosure.
Updated January 8, 20182018 List of Reportable Diseases in TennesseeFor LaboratoriesThe diseases, events, and conditions reportable to Tennessee Department of Health (TDH) by laboratories, including laboratories inhealthcare facilities, are listed below for 2018. Refer to Page 1 of this document for a list of diseases, events, and conditions reportableby healthcare providers. Laboratories should refer to the Detailed Laboratory Guidance document for additional guidance on reportabletests and results, and specimen/isolate submission to the Tennessee Department of Health Laboratory.Laboratory reports, and the reporting form (PH-1600) (if needed), may be faxed directly to the local or regional health office(see aldepartments.html)or the Communicable and Environmental Diseases andEmergency Preparedness (CEDEP) Division at (615) 741-3857. The PH-1600 also is available for completion online athttps://redcap.health.tn.gov/redcap/surveys/?s XTJTN4MD3D. More information about reporting is available on the Reportable Diseaseswebsite at https://apps.health.tn.gov/ReportableDiseases. For questions, contact CEDEP at (615) 741-7247 or (800) 404-3006.Disease Outbreaks (e.g., foodborne,healthcare-associated, waterborne) !Acinetobacter species: CarbapenemeipResistantAnaplasma phagocytophilum, speciesBabesia speciesBacillus anthracis !Bordetella pertussis Borrelia burgdorferiBrucella species California/LaCrosse Serogroup virusesCampylobacter speciesCandida auris (includes rule-out) Chikungunya virus Chlamydia psittaciChlamydia trachomatisClostridium botulinum or botulinum toxin:Foodborne ! , Wound !InfanteipClostridium difficileClostridium tetaniColistin-resistant (plasmid-mediated) gramnegative bacteria Corynebacterium diphtheria, ulcerans Coxiella burnetii Cryptosporidium speciesCyclospora speciesDengue virusEhrlichia speciesEnterobacteriaceae: Carbapenem-Resistant(all genera)Enterococcus species: Vancomycin-ResistantInvasive DiseaseSpecimen or Isolate Submission:RequiredEscherichia coli: Extended SpectrumeipBeta Lactamase-ProducingEscherichia coli: Shiga toxin-producingEquine Encephalitis viruses: Eastern ,Venezuelan , WesternFrancisella: tularensis , species Haemophilus influenzae Hepatitis, Viral- Type A Hepatitis, Viral- Type B: AcuteHepatitis, Viral- Type B: Perinatal (age 24months), Pregnant Female (each pregnancy)Hepatitis, Viral- Type C: Acute, ChronicHuman Immunodeficiency VirusInfluenza A virus: Novel !Klebsiella species: Extended SpectrumeipBeta Lactamase-ProducingLead LevelsLegionella speciesListeria speciesMeasles virus !Meningitis: Other Bacterial Middle East Respiratory Syndrome coronavirus(MERS-CoV) !Mumps virus Mycobacterium lepraeMycobacterium nontuberculous species(extra-pulmonary only)Mycobacterium tuberculosis complex(M. tuberculosis, M. bovis, M. africanum,M. canettii, M. microti) Neisseria gonorrhoeaeNeisseria meningitidis !Plasmodium speciesPoliovirus Pseudomonas aeruginosa: CarbapenemeipResistantRabies virus: Animal, Human !Ricin toxin !Rickettsia species (other than R. typhus)Rubella virus St. Louis Encephalitis virusSalmonella: Typhi , other speciesShigella speciesStaphylococcus aureus:Enterotoxin B-producing (pulmonary) !eipMethicillin-Resistant Invasive DiseaseToxin-producing (TSST-1)Vancomycin Non-Sensitive (All Forms) Streptococcus agalactiae Invasive DiseaseStreptococcus pneumoniae Invasive DiseaseStreptococcus pyogenes:Invasive Disease Toxin-producingTreponema pallidum:Congenital ,OtherTrypanosoma cruziVariola virus (Orthopox virus) !Vibrio: cholerae , speciesViral Hemorrhagic Fever viruses(including Ebola, Lassa, Marburg) !West Nile virusYellow Fever virus Yersinia: pestis , speciesZika virus RequestedFor more details about the laboratory tests and results, specimen or isolate submission requirements, and catchment areas for individual pathogens, please refer to the 2018 ReportableDiseases in Tennessee: Detailed Laboratory Guidance.Regular Reporting:Special Reporting:PH-1600 only in 1 week (all diseases for Regular Reporting)All blood lead test results must be reported electronically or via fax. For moreinformation, refer to lead/for-providers.html or email UT Extension at leadtrk@utk.edu for assistance.Phone immediately PH-1600 in 1 weekPhone next business day PH-1600 in 1 weekEffective January 1, 2018eipRefer to the Detailed Laboratory Guidance for catchment and/or send questionsto HAI.Health@tn.gov.2018 List of Reportable Diseases in TennesseePage 2 of 2
ed2018 Reportable Diseases in Tennessee: Detailed Laboratory GuidanceUpdated January 8, 2018Directions for Laboratory ReportingThe diseases, events, and conditions reportable to Tennessee Department of Health (TDH) by laboratories for 2018, including laboratories in healthcarefacilities, are provided in the 2018 List of Reportable Diseases in Tennessee: For Laboratories (Page 2 of the List). This Detailed Laboratory Guidancedocument (referenced in the List) provides additional details regarding the reportable tests and results, specimen source, and specimen/isolatesubmission to the Tennessee Department of Health Laboratory. Refer to .html for additionaldetails about submission. Please contact the TDH Laboratory at (615) 262-6300 before submitting specimens or isolates for pathogens requiringimmediate notification. Please refer to Page 5 of this document for blood lead test reporting.Laboratories should report via electronic laboratory reporting or a printed laboratory report. Requirements for electronic laboratory reporting are available at ng.html. Requirements for printed laboratory reports are below:(1) Patient demographics (including patient date of birth, address, sex, race, ethnicity, and telephone)(2) Ordering provider and facility name, phone number, address(3) Performing laboratory name, phone number, and address(4) Reporting facility name, phone number, address(5) Date of the laboratory report(6) Test performed (may differ from the test ordered)(7) Accession number(8) Specimen type/source and collection date(9) Result (quantitative and qualitative), interpretation, and reference rangeoooooIf the printed laboratory report does not include the required information listed above, then the PH-1600 should be completed for themissing information and submitted with the printed laboratory report.Laboratories are not required to report information in the Clinical Information section of the PH-1600.The PH-1600 is available on the Reportable Diseases website at ratories also may report online at https://redcap.health.tn.gov/redcap/surveys/?s XTJTN4MD3D, where the PH-1600 may becompleted and an electronic version of the paper laboratory report attached.Laboratory reports and the PH-1600, if necessary, may be faxed directly to the local or regional health office /localdepartments.html) or the Communicable and Environmental Diseases andEmergency Preparedness (CEDEP) Division at (615) 741-3857.For questions, contact CEDEP at (615) 741-7247 or (800) 404-3006.Effective January 1, 2018Page 1
Updated January 8, 20184ed2018 Reportable Diseases in Tennessee: Detailed Laboratory GuidanceLaboratory Tests and Results to Report to Public Health 2SendIsolateor 3SpecimenDetection in one or more specimensof etiological agents of disease orconditions, not limited to those listedin this document, are of urgent publichealth significance !Detection in one or more specimens of etiological agents of disease or conditions not limited to those listed in this document that are of urgent public healthsignificance. Laboratories reporting outbreak events or conditions not listed in this Table but of public health significance should immediately contact the TDHCommunicable and Environmental Disease Services via telephone at (615) 741-7247 or 1-800-404-3006.By RequestAcinetobacter species,eipCarbapenem-resistantAcinetobacter species from normally sterile sites, or urine and non-susceptible isolates (intermediate or resistant to at least one carbapenem or PCR detection ofcarbapenemase-producing gene). Results should not be sent via electronic laboratory reporting. Please include susceptibility test results. Report only forresidents of Davidson, Cheatham, Robertson, Sumner, Wilson, Rutherford, Dickson, or Williamson counties. Contact hai.health@tn.gov forclarification/questions.--Anaplasma phagocytophilum, speciesPositive by any method for any specimen. Include speciation results if known.--L&PBabesia speciesPositive by any method for any specimen.--L&PBacillus anthracis ! Positive by any method for any specimen.RequiredL&PBordetella pertussis Positive culture or detected by nucleic acid amplification or polymerase chain reaction (PCR) for any specimen.--L&P--L&PRequiredL&P--L&PBorrelia burgdorferi1) A positive culture for B. burgdorferi2) A positive two-tier test. This is defined as a positive or equivocal enzyme immunoassay (EIA) or immunofluorescent assay (IFA) followed by a positive IgM orIgG Western immunoblot (WB) for Lyme disease. An IgM WB is considered positive when at least two of the following three bands are present: 24 kDa (OspC)*, 39 kDa (BmpA), and 41 kDa (Fla).Disregard IgM results for specimens collected 30 days after symptom onset. An IgG WB is considered positive when at least five of the following 10 bands are present: 18 kDa, 24 kDa (OspC)*, 28 kDa, 30 kDa, 39 kDa (BmpA), 41kDa (Fla), 45 kDa, 58 kDa (not GroEL), 66 kDa, and 93 kDa.3) A positive single-tier IgG WB test for Lyme disease (see above for how to identify a positive IgG WB). While a single IgG WB is adequate for surveillancepurposes, a two-tier test is still recommended for patient diagnosis.ReporterPathogen 1L&PL*Depending upon the assay, OspC could be indicated by a band of 21, 22, 23, 24 or 25 kDA.Brucella species Positive by any method for any specimen.California/LaCrosse serogroup viruses:California Encephalitis Virus,LaCrosse Encephalitis Virus,Jamestown Canyon Virus,Keystone Virus,Snowshoe Hare Virus,Trivittatus VirusPositive IgM. Quantitative IgG indicating a positive test result. Isolation of virus or demonstration of specific viral antigen or nucleic acid. Virus-specific neutralizingantibodies. Any specimen.Campylobacter speciesPositive by any method (including culture, EIA, and PCR) for any specimen. Include speciation results if known. Submit specimen/isolate to the TennesseeDepartment of Health Laboratory within 2 weeks of detection/isolation.RequiredL&PCandida auris (including rule-outCandida auris) Positive by any method for any specimen. Detection from any site/specimens (including swabs from skin). Please note: C. auris can be misidentified as a number ofdifferent organisms when using traditional biochemical methods for yeast identification such as VITEK 2 YST, API 20C, BD Phoenix yeast identification system, andMicroScan. See commendations.html for greater detail. If species identity cannot be determined or one ofthe species shown in the table at above URL is identified, please contact HAI team at (615) 741-7247. Such isolates are considered “rule out C.auris” isolates. C.auris and “rule out C.auris” isolates should be submitted urgently to the Tennessee Department of Health Laboratory. Contact hai.health@tn.gov forclarification/questions.RequiredL&PChikungunya virus Positive IgM. Quantitative IgG indicating a positive test result. Isolation of virus or demonstration of specific viral antigen or nucleic acid. Virus-specific neutralizingantibodies. Any specimen.--L&PEffective January 1, 2018Page 2
SendIsolateor 3Specimen4Updated January 8, 2018Reportered2018 Reportable Diseases in Tennessee: Detailed Laboratory GuidancePathogen 1Laboratory Tests and Results to Report to Public Health 2Chlamydia psittaciPositive or detected by culture, serology, or PCR for any specimen.--L&PChlamydia trachomatisPositive by any method for any specimen.--L&PClostridium botulinum o r botulinumtoxin: Foodborne ! or Wound !Positive by any method for any specimen.RequiredL&PClostridium botulinum or botulinumtoxin: InfantPositive by any method for any specimen.RequiredL&PPositive by any method for any specimen. Include methodology. Report only for residents of Davidson County. Contact hai.health@tn.gov forclarification/questions.RequestedL&PClostridium tetaniPositive by any method for any specimen.RequiredL&PColistin-resistant (plasmid mediated)gram negative bacteria Positive by any method for any known plasmid-mediated colistin resistance mechanisms (e.g., mcr-1 , mcr-2 ). Isolates/specimens from any specimen and bodysite (including screening tests to determine colonization). Excludes Proteus, Providencia, Morganella, and Serratia species. Submit isolates with MIC 4 for colistin.RequiredL&PCorynebacterium diphtheria orCorynebacterium ulcerans Positive culture from any clinical specimen or histopathology.RequiredL&PCoxiella burnetii Demonstration by serology: Phase I or phase II antigen IgG 1:128 by indirect immunofluorescence assay (IFA), Elevated phase II IgG or IgM by enzyme-linkedimmunosorbent assay (ELISA), dot-ELISA, or latex. Detection by PCR, demonstration by immunohistochemical methods (IHC), or detection by culture. Anyspecimen.--L&PRequiredL&PRequiredL&PClostridium difficileeipCryptosporidium speciesCyclospora speciesPositive by any method for any specimen. Include speciation results if known. Submit specimen/isolate to the Tennessee Department of Health Laboratory within 2weeks of detection/isolation.Positive by any method for any specimen. Include speciation results if known. Submit specimen/isolate to the Tennessee Department of Health Laboratory within2 weeks of detection/isolation.Dengue virusPositive IgM. Quantitative IgG indicating a positive test result. Isolation of virus or demonstration of specific viral antigen or nucleic acid. Virus- specific neutralizingantibodies. Any specimen.--L&PEhrlichia species (includingE. chaffeensis and E. ewingii )Positive by any method for any specimen. Include speciation results if known.--L&PEnterobacteriaceae, CarbapenemresistantAny organism from the Enterobacteriaceae family (including but not limited to Escherichia coli, Enterobacter species, and Klebsiella species), from any clinicalspecimen (including rectal/perirectal swabs), resistant to at least one carbapenem antibiotic according to break points effective as of 2012 CLSI guidelines (i.e.,ertapenem MIC 2.0 or doripenem/imipenem/meropenem MIC 4.0). Include all susceptibility results with the numeric MIC values (interpretation alone isinsufficient), and all carbapenemase-production (Carba NP or modified-Hodge) or resistance mechanism testing results (positive or negative). For example,polymerase chain reaction [PCR] or metallo-β-lactamase for Klebsiella pneumonia carbapenemase [KPC], New Delhi metallo-β-lactamase [NDM], Veronaintegron encoded metallo-β-lactamase [VIM], the imipenemase [IMP] metallo-β-lactamase, or OXA-48 carbapenemase). For Proteus spp., Providencia spp., andMorganella morganii: only submit isolates from these genera if elevated MICs are observed for ertapenem, meropenem, or doripenem, as these isolates exhibitintrinsic resistance to imipenem. Contact hai.health@tn.gov for clarification/questions.RequiredL&PEnterococcus species, VancomycinresistantIsolation of enterococci from any clinical specimen from a sterile site AND "Nonsusceptible" isolate (i.e., intermediate- or high level resistant) to vancomycin. Pleaseinclude susceptibility test results.--L&PEffective January 1, 2018Page 3
Pathogen1Laboratory Tests and Results to Report to Public Health2SendIsolateor3Specimen4Updated January 8, 2018Reportered2018 Reportable Diseases in Tennessee: Detailed Laboratory GuidanceEquine encephalitis viruses: Eastern , Venezuelan , WesternPositive IgM. Quantitative IgG indicating a positive test result. Isolation of virus or demonstration of specific viral antigen or nucleic acid. Virus- specific neutralizingantibodies. Any specimen.--Escherichia coli, Extended SpectrumeipBeta Lactamase-producingE. coli resistant to at least one extended-spectrum cephalosporin (ceftazidime, cefotaxime or ceftriaxone), using the 2017 CLSI breakpoints. Include all susceptibilityresults with the numeric minimum inhibitory concentration values, and the results (positive or negative) of all carbapenemase-production or resistance mechanismtesting. Report only from sentinel laboratories (Maury County, Williamson County). Any specimen. Results should not be sent via electronic laboratory reporting.Contact hai.health@tn.gov for clarification/questions.RequestedEscherichia coli, Shiga toxinproducingPositive by any method (including culture, EIA, and PCR) for any specimen. Include speciation results if known. For state public health labs, please include negative,not isolated, and no growth results. For any Shiga toxin-producing Escherichia coli (STEC), including E. coli O157s and E. coli non-O157s, EIA positive broths for shigalike toxin will also be accepted. Submit specimen/isolate to the Tennessee Department of Health Laboratory within 2 weeks of detection/isolation.RequiredFrancisella tularensis , species Positive by any method for any specimen. Francisella tularensis is reportable by both laboratories and healthcare providers. Isolates/specimens are required forsubmission to the Tennessee Department of Health Laboratory. Species other than Francisella tularensis are reportable only by laboratories and do not requiresubmission to the Tennessee Department of Health Laboratory.RequiredHaemophilus influenza Positive culture or PCR from a sterile site.RequiredL&PHepatitis A virus Positive IgM anti-HAV for any specimen. Include associated results for additional serological markers for hepatitis (including hepatitis B and C), and alanineaminotransferase (ALT) and aspartate aminotransferase (AST) if available.--L&PHepatitis B virus: AcutePositive hepatitis B surface antigen (HBsAg), positive IgM antibody to hepatitis B core antigen (IgM anti-HBc), positive hepatitis B "e" antigen (HBeAg) or positivenucleic acid test for hepatitis B DNA (HBV-DNA; including qualitative, quantitative and genotype testing). Include pregnancy status and additional associatedserological markers for hepatitis (including hepatitis A and C) and alanine aminotransferase (ALT), if available. Any specimen.--L&PHepatitis B virus:Perinatal (age 24 months)Positive hepatitis B surface antigen (HBsAg), positive hepatitis B "e" antigen (HBeAg), or detectable HBV DNA. Any specimen.--L&PHepatitis B virus:Pregnant Female (each pregnancy)Positive hepatitis B surface antigen (HBsAg), positive IgM antibody to hepatitis B core antigen (IgM anti-HBc), positive hepatitis B "e" antigen (HBeAg) or positivenucleic acid test for hepatitis B DNA (HBV-DNA; including qualitative, quantitative and genotype testing). Include pregnancy status and additional associatedserological markers for hepatitis (including hepatitis A and C) and alanine aminotransferase (ALT), if available. Any specimen.--L&P--L&P--L&PRequiredL&PL&PLL&PL&PThe condition of acute HCV is reportable by both laboratories and providers. The condition of chronic HCV is reportable by laboratories only.Hepatitis C virusPositive anti-HCV and confirmatory assay (e.g. antigen or nucleic acid amplification testing for HCV RNA [qualitative, quantitative or genotype testing]). Include allassociated results (positive or negative) for additional serologic markers of hepatitis (including hepatitis A and B) and alanine aminotransferase (ALT) if availableAND all negative HCV confirmatory assays (e.g. antigen or nucleic acid amplification for HCV RNA [qualitative, quantitative or genotype testing]). Any specimen.HIV confirmatory test positive by any method for any specimen, CD4 Count, CD4 %, HIV Viral Load Count, HIV Viral Load Log Count. Reportable by laboratories only.Human Immunodeficiency Virus (HIV)HIV-1 Genotype Nucleotide Sequences. Reportable by laboratories with electronic lab reporting ability.In accordance with T.C.A. §37-1-403, any physician or other person diagnosing or treating venereal herpes or any of these reportable sexually transmitted diseasesin a child 13 years of age or younger should make a confidential written report of the case to the Department.Influenza virus, detection of a novelor pandemic influenza A virusstrain from a human !Effective January 1, 2018Positive viral culture or PCR for any specimen.Page 4
Pathogen 1Laboratory Tests and Results to Report to Public Health 2Klebsiella species, Extended SpectrumeipBeta Lactamase-producingKlebsiella species, resistant to at least one extended-spectrum cephalosporin (ceftazidime, cefotaxime or ceftriaxone), using the 2017 CLSI breakpoints. Include allsusceptibility results with the numeric minimum inhibitory concentration values, and the results (positive or negative) of all carbapenemase-production orresistance mechanism testing. Report only from sentinel laboratories (Maury County, Williamson County). Any specimen. Results should not be sent via electroniclaboratory reporting. Contact hai.health@tn.gov for clarification/questions.All laboratories that run blood lead tests and those who conduct on site blood lead analysis with portable devices are to report all blood lead test results forTennessee residents. Elevated blood lead levels ( 5 µg/dL) should be reported within 1 week and those 5 µg/dL should be reported within 1 month. Reportsshould include Patient's First Name, Last Name, Date of Birth, Gender, Race, Ethnicity, Address (Street Address, City, State, Zip Code and County of Residence),Sample Date, Sample Type, Result, Provider's Name and Phone Number and Payment Source.Lead levelsSendIsolateor 3SpecimenRequested4Updated January 8, 2018Reportered2018 Reportable Diseases in Tennessee: Detailed Laboratory GuidanceL--L&PAll blood lead test results may be reported electronically or via fax. For more information, refer to lead/for-providers.html or email UT Extension at leadtrk@utk.edu for assistance.Legionella speciesPositive by any method for any specimen.RequiredL&PListeria speciesPositive by any method (including culture and PCR) for any specimen. Include speciation results if known. Submit specimen/isolate to the Tennessee Departmentof Health Laboratory within 2 weeks of detection/isolation.RequiredL&PPositive IgM or rising IgG titer or detected by nucleic acid amplification or positive viral culture for any specimen.RequiredL&PMeningitis, isolation or demonstrationof any bacterial species fromcerebrospinal fluid Isolation of any bacteria from cerebrospinal fluid by culture, antigen, or PCR testing.RequiredL&PMiddle East Respiratory SyndromeCoronavirus (MERS- CoV) !Positive by any method for any specimen.RequiredL&PMumps virus Positive IgM or rising IgG titer or detected by nucleic acid amplification or positive viral culture for any specimen.RequiredL&PMycobacterium lepraeDemonstration of acid-fast bacilli in skin or dermal nerve.RequiredL&PMycobacterium species other than M.tuberculosis (non-pulmonary sitesonly)Any AFB smear, culture, HPLC, DNA probe or nucleic acid amplification test (NAAT) from any non-pulmonary site indicating presence of acid-fast bacilli. All specimens,except respiratory.RequestedL&PThe first AFB-positive respiratory specimen (by fluorochrome or acid-fast stain) indicating presence of acid-fast bacilli; submit specimen within 3 business days ofcollection.RequiredL&PAny specimen, from any site, with a positive nucleic acid amplification test (NAAT --- including, but not limited to: PCR, MTD, GeneXpert, MTBDR Plus [HAIN test])indicating detection of Mycobacterium tuberculosis complex or associated point mutation from any site; submit specimen within 3 business days of test result. RequiredL&PAny culture result by HPLC or DNA probe positive for Mycobacterium tuberculosis complex from any site; submit isolate within 5 business days of test result. RequiredL&PAll anti-TB drug susceptibility results, by molecular or dilutional method, from a specimen or isolate from any site, with confirmed presence of Mycobacteriumtuberculosis; anti-TB drugs include: isoniazid, rifamycins, pyrazinamide, ethambutol, streptomycin, levofloxacin, moxifloxacin, amikacin, capreomycin, kanamycin,cycloserine, ethionamide, para-aminosalicylate (PAS), clofazimine, bedaquiline, delamanid, linezolid, amoxicillin-clavulanate, and imipenem. RequiredL&PPositive interferon-gamma release assay (IGRA) test results (including, but not limited to: QuantiFERON -TB Gold In-Tube, QuantiFERON Plus, T-Spot.TB test), forpersons of any age; provide qualitative and quantitative positive IGRA results within 1 week of specimen collection.--L&PPositive by any method for any specimen.--L&PMeasles virus!Mycobacterium tuberculosis complex(M. tuberculosis, M. bovis, M.africanum, M. canettii, M. microti)Neisseria gonorrhoeaeEffective January 1, 2018Page 5
SendIsolateor 3Specimen4Updated January 8, 2018Reportered2018 Reportable Dis
Laboratories in healthcare facilities should refer to the information below. Healthcare providers and laboratories in the same healthcare facility both have a duty to report. Reporting Guidance . The diseases, events, and conditions reportable to Tennessee Department of Health (TDH) by laboratories for 2018, including laboratories in healthcare .
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