Avon Global Breast Cancer Clinical Scholars Program - Boston University

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Avon Global Breast Cancer Clinical Scholars Program2016 Request for ApplicationsRelease date:July 6, 2015Application due date:September 9, 2015*(Early applications are encouraged )2016 Scholars announced:October 28, 2015* 11:59 pm EST. Late applications will not be accepted Due to the complexity of the online application, applicants are encouraged to start and submittheir application early. Applications may be submitted at any time before the due date.Avon Foundation for WomenNew York, NY USAProgrammatic or Technical Support: grantinfo@avonfoundation.orgAvon Foundation for WomenThe Avon Foundation for Women, the world’s largest corporate-affiliated philanthropy focused on issues that matter most towomen, was founded in 1955 to improve the lives of women. Through 2014, Avon global philanthropy, led by the AvonFoundation, has donated more than 1 billion in more than 50 countries for causes most important to women. Today, Avonphilanthropy focuses on funding breast cancer research and access to care through the Avon Breast Cancer Crusade, and effortsto reduce domestic and gender violence through its Speak Out Against Domestic Violence program. Visitwww.avonfoundation.org for more information.

Table of ContentsApplication InstructionsI. Funding ObjectivesII. Guidelines on Use of AwardIII. Eligibility CriteriaIV. Key DatesV. Application Details / Selection ProcessVI. Scholars ActivitiesVII. Award NotificationVIII. StipendIX. Global Scholar Participation and Reporting Requirements333447789AppendicesA. Links to Templates for Required AttachmentsB. Participating Host InstitutionsC. Host Institutions and Mentors99102

Application InstructionsI. Funding ObjectivesTo provide clinically-focused scholarship opportunities for breast cancer specialists fromoutside the United States to receive advanced training at a leading U.S. breast cancer centeraffiliated with the Avon Foundation for Women. The Avon Global Scholars will take advancedskills back to their home countries to improve treatment and care of women facing breastcancer.II. Guidelines on Use of AwardThe program will bring up to 20 outstanding clinician scholars to Avon Foundation-fundedbreast cancer centers in the U.S. for a 4-week intensive training/preceptorship for them tolearn or become expert at new clinical skills. Due to medical malpractice laws in the U.S., thesepreceptorships will primarily be observational in nature. The exact work plan for the Scholar’sactivities and goals will be developed jointly by the Scholar and Mentor during the course of theapplication process and beyond. All Scholars will begin April 27, 2016 (tentative) in the U.S. with introductory course workand dialogue with leading breast cancer experts on April 28-29, 2016.Scholars will travel to the city of their host institution and attend clinical training from May2 – June 1, 2016.Scholars will attend the ASCO Annual Meeting, June 3-7, 2016 in Chicago.Following ASCO, Scholars will return to their home countries.December 1, 2016: 6-month progress report due to Avon Foundation.June 1, 2017: Final progress report due to Avon Foundation.III. Eligibility CriteriaScholars will be physicians (M.D., D.O., F.A.C.P., or equivalent) working in breast cancer clinicalcare, who are primarily early to mid-career and who will benefit from a short program ofadvanced, intensive training at a leading U.S. medical center.Eligible applicants are experienced licensed physicians or other health care professionals of anynation who devote a majority of their professional activity to breast cancer patient care. Idealcandidates will have an interest in improving breast cancer screening, treatment and outcomesin their countries.Scholars must have approval from their home institutions and a commitment from their homeinstitution that they have an employment position upon their return home. Scholars mustcommit to arriving in the U.S. to begin the program on April 27, 2016, attending the entireAvon program, provide progress reports at 6 months and 1 year and agree to share anddisseminate their new skills with other experts upon their return home.3

IV. Key DatesJuly 6, 2015September 9, 2015 (11:59pm EST*)October 28, 2015November 16, 2015November 16, 2015November 16, 2015RFA Release DateApplication due (Early applications are encouraged )2016 scholars announcedDeadline to accept / decline awardScholars must apply for Visa, if neededMentors must begin seeking approvals for hosting clinicalscholarApril 27, 2016April 28-29, 2016May 2 – June 1, 2016June 3-7, 2016June 7-8, 2016All Scholars must arrive in the U.S. no later than April 27thScholars attend introductory seminar / site visitsClinical training at host institutionScholars attend ASCO Annual MeetingScholars return homeDecember 1, 2016June 1, 20176-month progress report due to Avon FoundationFinal progress report due to Avon Foundation* No late applications will be acceptedV. Application Details / Selection ProcessAll application materials must be in English and must be submitted using the Avon Foundation’sonline application program. All application materials and attachments must be submittedelectronically. A tutorial on how to use the online system is posted on our global-scholars-tutorial-application-2016.pdf Due to the complexity of the online application, applicants are encouraged to start andsubmit their application early. Applications may be submitted at any time before the duedate.When accessing an application for the first time you will be prompted to create an applicationaccount using your email address as the user id and a password of your choosing. It isimperative that you use a functional, monitored email address as your log‐in email, as that isthe address that will be recorded in the system to receive email correspondence.To start a new application, go tohttps://www.grantrequest.com/SID 1102?SA SNA&FID 35045To log back into an application that you have previously started and saved, go tohttps://www.grantrequest.com/SID 1102/Default.asp4

2016 Avon Global Breast Cancer Clinical Scholars ApplicationThe application includes the following components:A.B.C.D.E.F.G.H.Contact InformationProgram InformationChoice of Host InstitutionsPreliminary Work Plan (use template)Full ResumeLetter of Support from Home Institution (use template)Personal Statement (use template)Scientific PublicationsA. Contact InformationThis section requests information about the Applicant including: First Name (Given Name) and Last Name (Surname or Family Name) Advanced Degree / Licensure Date of Birth Gender Passport Number Passport Expiration Date Country of Citizenship Field of Clinical Training Field of Research Training Applicant’s Home Institution (Primary place of employment) Applicant’s Title Mailing Address, including City, State, Postal Code and Country Phone Number Email Address Does Applicant Serve on Government Advisory Boards / Panels? If so, list. Does Applicant have Relationships with the Avon Company or with Avon ExecutiveStaff? If so, describe.B. Program InformationThis section requests information about the Applicant’s home country and programpreferences including: Provide a brief statement of breast cancer demographics and needs in home country Select three preferred areas of study Indicate top three choices of host institutionsC. AttachmentsAll attachments must be in English. Please upload only one file per attachment category. If youhave more than one document in any given category, combine all documents in to one file,then upload that one file. Accepted file formats are doc, docx and pdf. In order for the5

application to be considered complete, the following attachments must be uploaded to theapplication: Work Plan (required)Candidates are asked to develop and submit a preliminary work proposal outlining what theywish to learn while in the U.S. If candidate is selected, mentor and scholar will refine anddevelop the work plan over time. Please use this /gs-work-plan-template.docx. Upload work plan tothe attachments page of the online application by selecting the work plan upload box, clickingthe Browse button and locating the file to be uploaded on your computer, then clicking theUpload button. Full Resume (Biosketch or CV) (required)Resume must be translated into English. Upload resume on page to the attachments page ofthe online application by selecting the ‘Biosketch’ upload box, clicking the Browse button andlocating the file to be uploaded on your computer, then clicking the Upload button. Letter of Support from Applicant’s Home Institution (required)The Letter of Support from your home institution must contain specific information as outlinedin the template. Please download the template nstitutional-letter-of-support-template.doc. andshare it with the appropriate person at your organization to fill out (either the Chair of yourDepartment or the Director of your Institution). Once you receive a fully completed and signedfile, upload it to the attachments page of the online application by selecting the ‘Letter ofSupport from Applicant’s Home Institution’ upload box, clicking the Browse button to locate thefile to be uploaded on your computer, then clicking the Upload button. Personal Statement (required)The Personal Statement must contain specific information as outlined in the template. Atemplate for the personal statement can be found at this ersonal-statement-template.doc. Please providea personal statement discussing your career goals, why you want to participate in the AvonGlobal Breast Cancer Clinical Scholars Program, your preferred area of focus for advancedtraining and any additional professional areas of interest you would be working on while at aU.S. breast cancer center. Please download the template and save it to your computer. Oncecompleted, upload the Personal Statement to the attachments page of the online applicationby selecting the ‘Personal Statement’ upload box, clicking the Browse button to locate the fileto be uploaded on your computer, then clicking the Upload button. Up to two scientific publications may be included (optional)Publications must be in English. Please combine any and all publications into one file, andupload the one file to the attachments page of the online application by selecting the ‘ScientificPublications’ upload box, clicking the Browse button to locate the file to be uploaded on yourcomputer, then clicking the Upload button.6

Additional Letter(s) of Support (optional).Letters of support must be in English. Please combine all letters of support into one file, andupload the one file to the attachments page of the online application by selecting the‘Additional Letters of Support’ upload box, clicking the Browse button and locating the file to beuploaded on your computer, then clicking the Upload button.Application Selection ProcessA review panel composed of Avon Foundation Staff, Scientific Advisory Board members and adhoc experts as needed will rank applications and select candidates. Attempts will be made togeographically balance scholars. Finalists will be asked to undergo an interview by Avon viaphone or skype.Final Selection ProcessThe final selection for Avon Global Scholars awards will be based on a review of the applicationpackages and interviews.VI. Scholars’ ActivitiesScholars will be expected to develop a special project or curriculum of activities, incoordination with their assigned host mentor, relating to their interests and desiredadvanced training.A goal is to have defined skills, defined learning or a defined work-product by the end of thefour-week training that can be taken by the scholar back to his/her home institution.Examples of work products: Become expert at pathology techniques and quantifying ER/PR or HER2 marker staining Develop skills in core needle breast biopsy performance, interpretation and patientmanagement Increase understanding of how to structure and conduct multi-disciplinary review ofpatient cases and proposed treatment plan Understand how to develop a system of patient navigation or tracking in areas wherebarriers exist to delivery of long term follow up clinical care Increase skills in public health approaches to reducing stigma to breast cancer diagnosis,understanding benefits to cancer screeningVII. Award NotificationAll applicants will be notified of their selection status in early October 2015 (tentatively October1, 2015). Applicants selected will have until October 16th to decide whether they will accept ordecline the award. In the event a Recipient declines the award, an alternate will be contactedand offered the award. All award decisions are communicated via email and are final.7

VIII. StipendThe Avon Global Scholars stipend is not intended to completely cover all travel or dailyexpenses during the course of the program. For example, the award does not cover medicalcare, medical insurance, travel insurance or taxes. All incidentals (room service, telephone,laundry, movies, etc.) will be paid for by the recipient. The recipient is financially responsiblefor all travel, living and related expenses not covered as part of the Global Scholars programdescribed here. A weekly stipend of 400.00 USD will be provided to assist with living costs whileattending the Avon scholarship. The stipend will be calculated based on the number ofweeks the Scholar is studying at the host institution.In addition to the stipend: Avon will directly cover the costs of economy class air transportation from Scholar’shome country to New York; from New York to the city of the U.S. host institution; fromthe city of the U.S. host institution to Chicago; and from Chicago back to Scholar’s homecountry.o Scholar must arrange travel through Avon’s travel partner. Avon will arrange and cover the cost of Scholar’s initial ground transportation uponScholar’s arrival in New York, to travel from the airport to the host hotel. Scholars willbe responsible for arranging and paying for all transportation needs other than whenthey first arrive in New York from their home country. Avon will arrange and directly pay the costs of room and tax for housing during scholars’stay, including a hotel room in New York, housing for the four-week training, and hotelin Chicago. Housing is intended for the Scholar only and is not intended toaccommodate any other occupants. It is expected that most scholars will be on a sabbatical leave from their homeinstitution, and therefore will receive salary support from their home institution and beable to maintain any benefits (health insurance, retirement benefits) at their homeinstitution during the time period that they are Avon Global Scholars.IX. Global Scholar Participation and Reporting RequirementsAvon Global Scholars are required to communicate with their mentors prior to departure forthe U.S. Recipients are also encouraged to maintain contact with Mentors and fellowparticipants following their experience.Scholars are required to arrive in the U.S. no later than April 27, 2016 and attend the entireGlobal Scholar program.Scholars are required to submit a 6-month progress report due to Avon Foundation on or aboutDecember 1, 2016.8

Scholars are required to submit a Final progress report due to Avon Foundation on or aboutJune 1, 2017.APPENDIX A:Links to Templates for Required AttachmentsWork ork-plan-template.docxLetter of Support from Applicant’s Home ersonal /gs-personal-statement-template.docAPPENDIX B:Participating Host Institutions affiliated with the Avon Foundation for Women. All host sitesshould provide a multidisciplinary experience.InstitutionBaylor College of MedicineCityHoustonStateTXBoston Medical CenterBostonMACedars Sinai Medical CenterLosAngelesCAEmory University/Grady Memorial HospitalAtlantaGAStudy Opportunities Breast imaging Medical oncology Pathology Clinical trials & research Community health & patient navigation Screening & prevention programs Breast imaging Breast surgery Community health & patient navigation Breast imaging Breast surgery9

Houston MethodistHoustonTXJohns Hopkins UniversitySidney KimmelComprehensive CancerCenterMassachusetts GeneralHospitalBaltimoreMDBostonMANew York PresbyterianHospital-Columbia UniversityMedical CenterNew YorkNYNorthwestern UniversityChicagoILUCSF-San Francisco GeneralHospitalSanFranciscoCA Community health & patient navigationBreast imagingMedical OncologyScreening & prevention programsBreast imagingBreast surgery & reconstructionMedical oncologyPathologyBreast imagingBreast surgeryMedical oncologyPathologyClinical trials & researchBreast imagingBreast surgeryMedical oncologyPathologyClinical trials & research Breast imagingBreast surgery & reconstructionPathologyBreast imagingCommunity health & patient navigationPathologyAPPENDIX C:Host Institutions and MentorsBaylor College of MedicineHouston, TXMatthew Ellis, BSc. MB, BChir, PhD, FRCPBaylor College of Medicine (BCM) was founded in 1900, affiliated with Baylor University in 1903, and becamean independent institution in 1969. It was ranked as 1 of the Top 25 medical schools in US News & WorldReport. Its mission is "To provide state-of-the-art medical care and customer service in an environmentdedicated to teaching these principles and discovering new ways to achieve them." BCM is affiliated with 9hospitals, including Ben Taub General Hospital and its new Smith Clinic of the Harris Health System (HHS).HHS had more than one million outpatient visits in 2011. HHS and BCM have coordinated care for almost 50years.Dr. Matthew James Ellis is a native of the United Kingdom. He completed his medical degree at Queens’College & School of Clinical Medicine at the University of Cambridge in England, postgraduate clinical trainingat the Royal College of Physicians in London and gained a Ph.D. at the Royal Postgraduate Medical School andImperial Cancer Research Fund at the University of London. After a medical oncology fellowship at theLombardi Cancer Center, Georgetown University, Washington DC, he was an Assistant Professor there until10

moving to Duke University in 2000 and subsequently to Washington University in St Louis where he served asprofessor of medicine and section head of breast oncology until 2014. Ellis was recently recruited to BaylorCollege of Medicine to serve as the Director of the Lester and Sue Smith Breast Center and to hold the C. KentOsborne Chair of Breast Oncology. Both the McNair Foundation and the Cancer Prevention Research Instituteof Texas recently awarded him scholarships. He has been instrumental in developing a Genome Atlas andTherapeutic Road Map for estrogen receptor positive breast cancer by applying genomic techniques tosamples accrued through a series of neoadjuvant endocrine therapy trials. Most recently, he has found thatmetastatic breast tumors harbor mutations and translocations in the estrogen receptor gene that render thetumor resistant to therapies used to block estrogen receptor function. He also pioneered research into theclinical relevance of activating mutations in HER2 and in the deployment of patient-derived xenografts for thepharmacological annotation of breast cancer genomes. He is currently Co-Chair of the translational medicinecommittee for the NRG cooperative group, co-leader for The Cancer Genome Atlas (TCGA) Breast Project andalso serves as a Co-PI for the Clinical Proteomic Tumor Analysis Consortium that endeavors to translate TCGAgenomic discoveries into protein-based biomarkers with clinical utility. Dr. Ellis has a successful track recordin international clinical and translational research, with recent trainees from Brazil, Chile, Poland and Turkey.Boston Medical CenterBoston, MATracy Battaglia, MD, MPHBoston Medical Center (BMC) is a 496-bed academic medical center located in Boston’s historic South End.BMC provides a full range of pediatric and adult care services, from primary to family medicine to advancedspecialty care. Emphasizing community-based care, BMC is committed to providing consistently excellent andaccessible health services to all—and is the largest safety-net hospital in New England. BMC’s Breast HealthProgram incorporates a coordinated multi-specialty approach to care, linking internal medicine, surgicaloncology, radiology/mammography, medical oncology, radiation oncology, pathology and other breast healthspecialists together as one connected team. This patient-centered approach results in rapid access,personalized care and streamlined patient visits. All new patients are given expedited appointments in theBelkin Breast Health Center, where they are seen by either a medical or surgical breast specialist. A cancercare nurse is available to all breast cancer patients as a central contact to offer support and ensurecompliance throughout their multispecialty cancer care. They are conveniently located next door to theBelkin Breast Imaging Center if further diagnostic evaluation is needed. An essential part of the program is aweekly multidisciplinary breast cancer conference in which the entire team collaborates on a comprehensiveevaluation, and plans the best, most individualized treatment regimen and follow-up care for patients withbreast cancer.Dr. Tracy Battaglia is a graduate of Boston University School of Medicine and completed her residency at theBeth Israel Deaconess Medical Center. Additionally, she holds a Masters of Public Health from the BostonUniversity School of Public Health. Dr. Battaglia’s interests include breast and cervical cancer screening inminority and underserved women, reducing errors in follow-up to abnormal mammography, as well as riskperception and screening behaviors in multi-ethnic populations. She is Associate Program Director of theBoston University Preventive Medicine Residency Program and Co-Director of the Avon Breast HealthInitiative at Boston Medical Center. Additionally, Dr. Battaglia is a former recipient of Career DevelopmentAwards from both NIH and the American Cancer Society and now serves as a Principal Investigator on thePatient Navigation Research Program, a community-based cancer control project supported by the Center toReduce Cancer Health Disparities at the National Cancer Institute.11

Cedars Sinai Medical CenterLos Angeles, CAArmando Giuliano, MD, FACS, FRCSEdSince its inception in 1902, Cedars-Sinai has evolved to become the largest nonprofit hospital in the westernUnited States - one that is internationally renowned for the best patient care modern medicine has to offer.Today, Cedars-Sinai Medical Center is committed to providing superior outpatient, acute and sub-acutepatient care, breakthrough biomedical research, graduate and undergraduate medical education andcommunity service.In 2013, for the 18th year in a row, Cedars-Sinai has won the National Research Corporation's ConsumerChoice Award (NRC) for providing the highest quality medical care in the Los Angeles region based on asurvey of area households.Armando E. Giuliano, MD, is Executive Vice Chair of Surgery for Surgical Oncology, Co-director of the Saul andJoyce Brandman Breast Center - A Project of Women's Guild and Associate Director for Surgical Oncology atthe Samuel Oschin Comprehensive Cancer Institute. Additionally he is the Linda and Jim Lippman Chair inSurgical Oncology and serves as Program Director for both the Complex Surgical Oncology Fellowship andBreast Oncology Fellowship. He is a recognized authority in breast cancer, thyroid cancer, and parathyroiddisease.After graduating from Fordham University, Dr. Giuliano earned his medical degree from the University ofChicago. He trained in surgery at the University of California, San Francisco and surgical oncology at theUniversity of California, Los Angeles.Dr. Giuliano has served on the editorial boards of prestigious peer-reviewed journals, including the Annals ofSurgical Oncology, Journal of the American College of Surgeons and Breast Cancer Online. A prolificresearcher, he is the author of more than 450 scientific papers and has written book chapters and a textbook.Dr. Giuliano has earned numerous teaching awards as well as the Hadassah Medical OrganizationOutstanding Lifetime Achievement Award in Oncology, the Fellowship of the Royal College of Surgeons inEdinburgh ad hominem, the National Summit on Breast Cancer Outstanding Medical Advances in BreastCancer Award and the Umberto Veronesi Award for international recognition of contributions to the field ofbreast cancer and the introduction of sentinel node biopsy for the treatment of breast cancer. In 2011, hewas one of only three physicians to receive the national clinical Excellence Award from Castle Connolly.Recently he was awarded the Susan G. Komen for the Cure Brinker Award for Scientific Distinction in ClinicalResearch, their highest award for clinical research.In addition to serving as Chairman of the American College of Surgeons Oncology Group Breast Organ SiteResearch Committee, Dr. Giuliano served as Chairman of the Breast Fellowship Program Directors Committeefor the Society of Surgical Oncology. He recently completed his term as President of the InternationalSentinel Node Society and currently serves as Secretary for the Society of Surgical Oncology.Dr. Giuliano's work on nodal metastases has changed the treatment of breast cancer worldwide.12

Emory University/Grady Memorial HospitalAtlanta, GASheryl Gabram, MDOne of the largest public hospitals in the Southeast, Grady Memorial Hospital is an internationally recognizedteaching hospital with a historic commitment to the health needs of the most vulnerable. Grady MemorialHospital is a vital part of Emory University School of Medicine's commitment to metro Atlanta and Georgia,and is the location of the Georgia Cancer Center for Excellence.In 2005, Dr. Sheryl Gabram was recruited by Dr. Otis Brawley to lead the AVON Comprehensive Breast Centerwhere she became the principal investigator on the AVON Grant in 2009. In September 2009, Dr. Gabramappointed to Deputy Director of Cancer Center for Excellence at Grady. Then, in October 2011 she wasnamed Surgeon-in-Chief at Grady Memorial Hospital. Dr. Gabram current research focuses on decreasingdisparities for breast cancer patients. She serves as the medical liaison for the AVON community outreachand navigation program and is responsible for clinical access to high quality care for patients seen in theAVON Comprehensive Breast Center at Grady. From a predictive health perspective, she collaborates withresearchers from Georgia Tech on the examination of breath biomarkers in exhaled specimens as a potentialtool for breast cancer disease detection and monitoring. To date Dr. Gabram has authored over 65 peerreviewed journal publications.Dr. Gabram is the recipient of numerous awards and honors. She has been named by the patient resourceguide Castle Connolly as one of America’s Top Doctors for seven consecutive years and American’s TopCancer Doctors for five consecutive years. She has received the Arthur G. Michel, MD Award for Excellence inBreast Care from the Y-ME National Breast Cancer Organization and was selected as one of AtlantaMagazine’s Top Doctors in 2007 and 2009. In the November 2008 Women’s Health magazine she was namedone of 5 top oncologists for women in the South. Additionally, she is a member of several prestigiousprofessional societies including a Fellow of the American College of Surgeons, the Society of SurgicalOncology and the American Society of Breast Surgeons.Houston MethodistHouston, TXJenny C. Chang, MDHouston Methodist is comprised of a leading academic medical center in the Texas Medical Center and fourcommunity hospitals serving the greater Houston area. Each hospital is staffed with committed personnelwho exemplify the core values: integrity, compassion, accountability, respect and excellence. Patient safety,quality and service are the highest priorities.Houston Methodist Hospital, the system's flagship, is consistently listed among U.S. News & World Report'sbest hospitals and they extend that same level of quality care across the system.Dr. Jenny C. Chang is the Emily Herrmann Chair in Cancer Research and Director of the Cancer Center atHouston Methodist Hospital in Houston, Texas. She obtained her medical degree at Cambridge University inEngland, and then completed fellowship training in medical oncology at the Royal Marsden Hospital/Institutefor Cancer Research in the United Kingdom. She was also awarded a research doctorate from the Universityof London. There, she developed an interest in breast cancer, particularly in the area of prognostic andpredictive markers. She used the clinical situation of locally advanced breast cancer, in which patients aretraditionally treated with pre-operative therapy, to assess the use of such markers in predicting treatmentresponse. Her recent work has focused on the intrinsic therapy resistance of cancer stem cells, which haslead to several publications and international presentations. In addition, she has been awarded severalfederal grants to evaluate novel biologic agents, and holds patents on new technologic advances includinghigh throughput molecular profiling.13

Johns Hopkins University-Sidney Kimmel Comprehensive Cancer CenterBaltimore, MDBen Park, MD, PhDSince its opening in 1973, the Johns Hopkins University Cancer Center has led the world in deciphering themechanisms of cancer and new ways to treat it. One of only 40 cancer centers in the country designated bythe National Cancer Institute (NCI) as a Comprehensive

Scholars will travel to the city of their host institution and attend clinical training from May 2 - June 1, 2016. Scholars will attend the ASCO Annual Meeting, June 3-7, 2016 in Chicago. Following ASCO, Scholars will return to their home countries. December 1, 2016: 6-month progress report due to Avon Foundation.

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