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1 Curriculum Vitae Jeffrey C. Wang, MD CURRICULUM VITAE Jeffrey C. Wang, M.D. CURRENT POSITION: Professor, USC Department of Orthopaedic Surgery and Department of Neurosurgery Co-Director, USC Spine Center Chief, USC Orthopaedic Spine Service Keck School of Medicine at USC University of Southern California PRIOR POSITION: Professor, UCLA Department of Orthopaedic Surgery and Department of Neurosurgery Vice Chair, UCLA Department of Orthopaedic Surgery Clinical Operations Chief, Spine Service, Department of Orthopaedic Surgery UCLA (University of California Los Angeles) David Geffen School of Medicine BUSINESS ADDRESS: UCLA Spine Center 1250 16th Street, Suite 745 Santa Monica, CA 90404 Tel: (310) 319-3334 Fax: (310) 319-5055 jwang@mednet.ucla.edu PERSONAL: Place of Birth: Mitchell, South Dakota Married: Christina Wang Children: Christopher Wang (12/20/93) and Benjamin Wang (3/14/96) EDUCATION: 1979-1983 Fairmont Senior High School, Fairmont, West Virginia 1983-1987: B.S. in Biological Sciences with Departmental Honors Stanford University, Stanford, CA 1987-1991: M.D., Medical School, Cum Laude University of Pittsburgh School of Medicine, Pittsburgh, PA 1991-1996: Residency in Orthopaedic Surgery University of California, Los Angeles Dept. of Orthopaedic Surgery, Los Angeles, CA 1

2 Curriculum Vitae Jeffrey C. Wang, MD 1996-1997: Fellowship in Spine Surgery with Henry H. Bohlman, M.D. Case Western Reserve University Dept. of Orthopaedic Surgery, Cleveland, Ohio LICENSURE AND CERTIFICATION: American Board of Orthopaedic Surgery – Recertification – Passed 2006 American Board of Orthopaedic Surgery – Part I Examination – Passed 1996 American Board of Orthopaedic Surgery – Part II Oral Exams – Passed 1999 Medical License – #G76303 - California 1993 Medical License – #69963 - Ohio 1996 Medical License - #14237 – Nevada 2012 PROFESSIONAL ACTIVITIES: Western Orthopaedic Association (WOA) Program Chairman, Western Orthopaedic Association, Los Angeles Chapter Secretary-Treasurer, Western Orthopaedic Association, Los Angeles Chapter Vice President, Western Orthopaedic Association, Los Angeles Chapter President-Elect, Western Orthopaedic Association, Los Angeles Chapter President, Western Orthopaedic Association, Los Angeles Chapter 2001-2002 2002-2003 2003-2004 2004-2005 2005-2006 North American Spine Society (NASS) NASS Committee on Contemporary Concepts 2000-2003 NASS Society Scientific Program Committee 2002-Present North American Spine Society Committee on Recognition and Awards 2003-2008 NASS SpineLine Editorial Committee 2003-2010 NASS Task Force on New Technology 2005-2006 NASS Fundraising Task Force 2005-2007 NASS Museum Committee 2005-2008 NASS Board of Directors 2007–present Chair, NASS Section on Biologics and Basic Research 2007-2011 Chair, NASS Continuing Medical Education Committee 2008-2011 NASS Educational Council Director 2011 – present NASS Annual Meeting Program Chair 2005 and 2012 Scoliosis Research Society (SRS) Scoliosis Research Society New Technologies Committee 2004-2007 Scoliosis Research Society, Education Committee 2005-2007 Scoliosis Research Society, Research Grants Committee 2005–2008 Federations of Spine Associations (FOSA) FOSA, Executive Board 2005-2009 and 2011-present 2

3 Curriculum Vitae Jeffrey C. Wang, MD President, Federation of Spine Associations 2008 – 2009 Cervical Spine Research Society (CSRS) CSRS Committee on Research and Awards Cervical Spine Research Society, Research Committee Cervical Spine Research Society, Editorial Committee Cervical Spine Research Society Board of Directors Chair, CSRS Instructional Course Committee Cervical Spine Research Society Nominating Committee CSRS Chair of Program Committee Cervical Spine Research Society Program Chair Orthopaedic Chair of the Neuro-Ortho Society Liaison Committee 2004-2007 2005–2008 2006-2010 2006–present 2007-2010 2010-2011 2011 2011 2013 - present American Orthopaedic Association AOA – ABC Exchange Fellowship Committee Chair, AOA North American Traveling Fellowship Committee AOA Fellowships Coordination Chair AOA Executive Committee 2007-2008 2008-2012 2012-present 2012-present American Board of Orthopaedic Surgery ABOS Question Writing Task Force 2011-present California Orthopaedic Association (COA) California Orthopaedic Association Board of Directors 2008 – 2012 AOSpine North American Spine Education Committee, AO North America AOSpine North America Board of Directors Chairman, International Education, AOSpine Foundation Chairman, AOSpine International 2003-2004 2003-2006 2008-2011 2012-present International Society for Advancement of Spine Surgery Basic Science Program Chair, Spine Arthroplasty Society 2010 Interurban Orthopaedic Society (elected 2011) Membership committee 2011-present 2011-present American Academy of Orthopaedic Surgeons (AAOS) AAOS Adult Spine Evaluation Subcommittee 2010-present Expert Medical Reviewer for The Medical Board of California 2005–present 3

4 Curriculum Vitae Jeffrey C. Wang, MD ACADEMIC APPOINTMENTS: Professor of USC Orthopaedic Surgery Professor of USC Neurosurgery Chief, USC Orthopaedic Spine Service Co-Director, USC Spine Center Keck School of Medicine at USC Univeristy of Southern California 2013 - present Acting Chairman, UCLA Department of Orthopaedic Surgery 2010 – Sept. 23-26 2011 – Jan. 30, Feb. 23-28, Nov. 22-27 2012 – Feb. 7-8, Feb. 11-12, June 15-16, Aug. 7-10, Oct. 20-21 2013 – Jan. 2-9, May 16-18 Vice Chair of Clinical Operations UCLA Department of Orthopaedic Surgery 2012-2013 Professor of UCLA Orthopaedic Surgery Professor of UCLA Neurosurgery 2008 – 2013 2008 – 2013 Associate Professor of UCLA Orthopaedic Surgery Associate Professor of UCLA Neurosurgery Faculty Advisor in UCLA Biomedical Engineering 2003 - 2008 2003 – 2008 2004 - 2013 Assistant Professor of UCLA Orthopaedic Surgery Assistant Professor of UCLA Neurosurgery 1997 – 2003 2002 – 2003 Chief, Spine Service, UCLA Dept. of Orthopaedic Surgery 1997 - 2013 Executive Director, UCLA Comprehensive Spine Center 2003-2007 Attending Surgeon, UCLA Center for Health Sciences UCLA School of Medicine 1997 – 2013 Director, UCLA Orthopaedic Spine Fellowship UCLA Center for Health Sciences 1997 – 2013 Chief, Spine Service Attending Surgeon West Los Angeles, Veterans Administration Medical Center 1997 – 2007 4

5 Curriculum Vitae Jeffrey C. Wang, MD Adjunct Faculty Member, UCLA Department of Biomedical engineering 2013 2003 - HONORS AND AWARDS: 2013 – 8th Annual Henry H. Bohlman, MD Lecuture, Visiting Professor, Case Western Reserve University Dept. of Orthopaedic Surgery. May 21-22, 2013 2013 – Keynote Speaker at the Annual Meeting of the Brazilian Spine Society, Florianopolis, Brazil. April 27-28, 2013 2012 – Keynote Speaker at the 85th Annual Japanese Orthopaedic Association, Kyoto, Japan. May 18, 2012 2011 - Winner of the 4th annual The Spine Journal Editors’ Choice Award chosen as the top paper among those published in volume year 2010, chosen by the Executive Editorial Board of The Spine Journal. Cost and Utilization of Conservative Management of Lumbar Disc Herniation Prior to Surgical Discectomy, published in the June 2010 issue of The Spine Journal. 2011 – Visiting Professor, The University of Washington Dept. of Orthopaedics and Sports Medicine and the University of Washington Orthopaedic Alumni, Resident Graduation Research Day, May 20, 2011 2011 – Reviewer of the Year, Spine (Journal Reviewer of the year award) 2011 – Guest Speaker, 6th Annual Meeting of the Korean American Spine Society, Los Angeles, CA, July 8, 2011 2010 – Visiting Professor, Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine. Sept. 19, 2010 2010 – Keynote Speaker, The 17th Annual Meeting of the Japan Society for the Study of Surgical Technique for Spine and Peripheral Nerve, Yokohama, Japan, Sept. 17, 2010 2010 - American Society for Bone and Mineral Research (ASBMR) 2010 Annual Meeting, Toronto Canada, Award: 2010 President's Poster Competition Award for best Poster Presentation. October 16, 2010 2010 – Visiting Professor, Weill Cornell Medical College, Department of Neurological Surgery, June 14, 2010. 5

6 Curriculum Vitae Jeffrey C. Wang, MD 2010 – Keynote Speaker, the Annual Meeting of the American College of Spine Surgery, June 12, 2010. 2010 – Keynote Speaker, the 25th Annual Meeting of the Korean Society of Spine Surgery. 2010 – Keynote Speaker, BritSpine, The Sixth Combined Meeting of the British Scoliosis Society, Society for Back Pain Research, and the British Association of Spinal Surgeons, Liverpool, April 28, 2010 2010 – American Academy of Orthopaedic Surgeons Achievement Award 2010 – Who’s Who in Science and Engineering 2009 – Keynote Speaker, Argentina Spine Society, Buenos Aires, Argentina, Sept. 4-5, 2009 2009 – Keynote Speaker, The 3rd China International Congress and Exhibition of Orthopaedics, Beijing, China, August 6-9, 2009. 2009 – Visiting Professor, University of Toronto, June 19, 2009. 2009 – Visiting Professor, Texas Back Institute, Dallas, Texas, Feb. 13, 2009. 2009 – Keynote Speaker, Jeffrey C. Wang, MD., The 7th Annual Caribbean Neurosciences Symposium, Montego Bay, Jamaica, Jan. 23, 2009. 2008 – Visiting Professor, University of Michigan Annual Spine Meeting. Ann Arbor, Michigan, November 14, 2008. 2008 – Keynote Speaker, the Annual Meeting of the Taiwan Orthopaedic Association, Taipei, Taiwan, Oct. 24-26, 2008. 2008 – Keynote Speaker, the 4th Annual Meeting of the Taiwan Neurospinal Society, Kaohsiung, Taiwan, May 24-25, 2008. 2008 – Distinguished Visiting Professor, The 10th Annual Medical College of Georgia Orthopaedic Surgery Spine Forum, March 21, 2008. 2007 – Keynote Speaker, The 14th Annual Meeting of the Japan Society for the Study of Surgical Techniques for the Spine and Peripheral Nerves, Nagoya, Japan, September 14, 2007. 2007 – Keynote Speaker, AOSpine Degenerative Spine Course, Buenos Aires, Argentina, 6

7 Curriculum Vitae Jeffrey C. Wang, MD September 6, 2007. 2007 – Keynote Speaker, The Annual Venezuelan Neurosurgery Spine Society Meeting, Porlamar, Venezuela. May 24, 2007. 2007 – Visiting Professor, Thomas Jefferson University Hospital, Philadelphia, PA. May 21, 2007. 2007 - The 16th Annual Orthopaedic Hospital Research Day, Keynote Speaker. Los Angeles, CA. May 18, 2007. 2006 - President, Western Orthopaedic Association, Los Angeles Chapter 2006 – Cervical Spine Research Society Research Grant Award for Bone Morphogenetic Protein Binding Peptides (BBP) as an Adjuvant in Spinal Fusion, Dec. 2, 2006. 2006 – Keynote Speaker, The 29th Annual Meeting of the Singapore Orthopaedic Association, Singapore, Nov.8, 2006. 2006 – Visiting Professor, Queen Mary Hong Kong University Hospital, Hong Kong, China. Sept. 4, 2006. 2006 – Keynote Speaker, The Annual Meeting of the Korean Neurosurgery Spine Society, Sept. 2, 2006. 2006 – Visiting Professor, Inha University Hospital, Seoul, Korea, Aug. 28, 2006. 2006 – Visiting Professor, Kyung Hee University Medical Center, Seoul, Korea, Aug. 29, 2006. 2006 – Visiting Professor, Ewha Womens University Mokdong Hospital, Seoul, Korea, Aug. 30, 2006. 2006 – Visiting Professor, Youngdong Severance University Hospital, Seoul, Korea, Aug. 30, 2006. 2006 – Whitecloud Award for Best Basic Science Podium Presentation at the 13th International Meeting on Advanced Spinal Techniques, Athens, Greece. July 12-15, 2006. 2006 – Visiting Professor, Beijing University No.3 Hospital, Beijing, China, May 22, 2006. 2005 – Deputy Editor, The Spine Journal, Basic Science 7

8 Curriculum Vitae Jeffrey C. Wang, MD 2005 – Winner of 2nd Place Basic Science Research Award Presentation, the Annual Meeting of the Cervical Spine Research Society, San Diego, CA, Dec. 2, 2005. 2005 – Visiting Professor, Loyola University Department of Orthopaedic Surgery, Chicago, IL, Nov. 10, 2005 2005 – Visiting Professor, Rush University Medical Center Department of Orthopaedic Surgery, Chicago, IL, Nov. 9, 2005 2005 – Visiting Professor, Imperial College of London, Musculoskeletal Surgery, London, England. Oct. 25, 2005 2005 – Program Chairman, North American Spine Society, 20th Annual Meeting 2005 – Visiting Professor, University of Southern California Department of Orthopaedic Surgery, June 24, 2005 2005 – Visiting Professor, University of California Irvine Department of Orthopaedic Surgery, March 31, 2005. 2005 – Visiting Professor, Cedars-Sinai Medical Center, Institute for Spinal Disorders, March 16, 2005. 2004 – Cervical Spine Research Society 2004 Research Grant Award – A Prospective Study of cerebral Cortical Activation of Patients with Cervical Myelopathy Using Functional MRI 2003 – Presidential Guest Lecture, International Intradiscal Therapy Society 16th Annual Meeting, Chicago, IL. 2003 – The International Society for Optical Engineering (SPIE) 3rd place for Best Paper Award at the SPIE’s 7th Symposium on NDE for Health Monitoring and Diagnostics – “Interaction of Focused Ultrasound with Biological Materials” 2002 – North American Spine Society 2002 Outstanding Poster Presentation Award for Research, “An Economic Analysis of BMP for Fusion” 2000 – North American Spine Society Traveling Fellowship, Japan. 1999 – Scoliosis Research Society, Russell Hibbs Award for Outstanding Basic Science Research, presented at the Annual Meeting of the Scoliosis Research Society, San Diego, CA. 8

9 Curriculum Vitae Jeffrey C. Wang, MD 1999 – North American Traveling Fellow – American Orthopaedic Association 1999 – National Aeronautics and Space Administration (NASA) Class 1 New Technology Award: NPO-20632: Transcutaneous Spine Trauma and Disorders Treatment Using Ultrasonically Induced Confined Heat (ULICH) Zone. 1999 – Honorable Mention for Best Paper Award in Basic Science at the Annual Meeting of the International Society for the Study of the Lumbar Spine, Kona, Hawaii. 1998 – North American Spine Society Research Grant Award presented at the Annual Meeting of the North American Spine Society, San Francisco, CA, Oct. 30, 1998. 1996 -North American Spine Society Research Award for Outstanding Scientific Exhibit, presented at the Annual Meeting of the North American Spine Society, Vancouver, B.C., Oct. 25, 1996 1996 -Vernon P. Thompson Award for Outstanding Research, presented at the Annual Meeting of the Western Orthopaedic Association, Maui, Hawaii, August 4, 1996 1992 -University of Pittsburgh Outstanding Scholar Award 1991 -Cum Laude from University of Pittsburgh School of Medicine 1991 -Hewlett-Packard Top Medical Graduate Award for Academic Achievement 1990 -Alpha Omega Alpha (AOA) at University of Pittsburgh School of Medicine 1989 -Genelabs, Inc. Award for Outstanding Research Project 1989 1989 -University of Pittsburgh School of Medicine Research Grant 1988 -Genelabs, Inc. Award for Outstanding Research Project 1988 1988 -University of Pittsburgh School of Medicine Research Grant 1987 -University Honors from Stanford University Department of Biological Sciences MEMBERSHIPS: American Academy of Orthopaedic Surgeons Cervical Spine Research Society North American Spine Society Scoliosis Research Society 9

10 Curriculum Vitae Jeffrey C. Wang, MD Spine Arthroplasty Society Western Orthopaedic Association California Orthopaedic Association Alpha Omega Alpha Honor Society Western Orthopaedic Association Interurban Orthopaedic Society Association of Bone and Joint Surgeons EDITORIAL BOARDS Editor/Reviewer for Spine, 2000 – present. Editor/Reviewer for The Journal of Spinal Disorders, 2001 - present. Editor/Reviewer for Advances in Osteoporotic Fracture Management, 2001 – present. Editorial Board/Editor for Journal of Minimally Invasive Spinal Technique, 2001 – present. Editor/Reviewer for SpineLine, 2003 – 2010 Editor/Reviewer for The Spine Journal, 2003 – present Reviewer for the Journal of the American Academy of Orthopaedic Surgeons, 2004 – present Reviewer for Clinical Orthopaedics and Related Research, 2004 – present Reviewer for International Journal Artificial Intelligence in Medicine 2005 – present Reviewer for Archives of Physical Medicine and Rehabilitation, 2005 – present Deputy Editor for The Spine Journal, 2005 – 2010 Editorial Board, OKU: Spine 3 – 2006 Editorial Board, OKU 9, 2006 Editorial Board for The Journal of Orthopaedic Surgery, 2006 – present Reviewer for the Journal of the American Medical Association, 2007 – present Reviewer for Surgical Neurology, 2007 – present Reviewer for Journal of Chinese Medicine International, 2008 – present Reviewer for Journal of Biomedical Materials Research, 2008 – present Reviewer for Neuroradiology 2009- present Editorial Board for Spine Arthroplasty Society Journal, 2008 – present Reviewer for The Journal of Orthopaedic Research, 2009 - present Editorial Board for Case Reports in Medicine, 2009 – present Reviewer for Neurosurgery, 2009-present Editorial Review Board for Journal of the American Academy of Orthopaedic Surgeons 2009-present Co-Managing Editor, Evidence Based Spine Care Journal 2010 – present Reviewer for Expert Opinion On Medical Diagnostics, 2010 – present Editorial Board for World Journal of Orthopaedics, 2010 – present Associate Editorial Board, Spine, 2011 – present Editorial Board, OKU 10, (Section Editor for Spine), AAOS, 2011 Editor-in-Chief, The Global Spine Journal, 2011 – Present Reviewer for Journal of Orthopaedic Trauma 2013 – present 10

11 Curriculum Vitae Jeffrey C. Wang, MD Reviewer for Tissue Engineering and Regenerative Medicine 2013 - present COMMITTEES 1997-2013 1997-2007 1997-2007 1997-2000 1998-2001 1998-2006 1999-2013 2001-2007 2002-2013 2005-2013 2009-2013 2010-2013 Orthopaedic Resident Selection Committee, UCLA Dept. of Orthopaedic Surgery Department of Veterans Affairs Task Force on Chronic Pain Management, West LA VA Hospital Department of Veterans Affairs Merit Review Board Medical Research Service, Reviewer UCLA School of Medicine Grant Advisory Committee for Health Resources Study on “Spinal Manipulation for Acute Neck Pain” UCLA Hospital Clinical Effectiveness Committee, Orthopaedic Surgery Representative, UCLA Center for Health Sciences UCLA Executive Trauma Committee, Director of Spine Trauma, Orthopaedic Surgery, UCLA Center for Health Sciences UCLA Department of Orthopaedic Surgery Promotions Committee UCLA Department of Orthopaedic Surgery Steering Committee UCLA Comprehensive Spine Center Executive Steering Committee UCLA Appointments and Promotions Committee Co-Chairman, UCLA Combined Orthopaedic and Neurosurgery Spine Center Committee Chairman, UCLA Dept. of Orthopaedic Surgery Clinic Committee COMMUNITY SERVICE: Scoliosis screening for St. Paul the Apostle Middle School 2002-present GRANTS AND FUNDING: “Development of a Rodent Spinal Fusion Model” UCLA Academic Senate Research Seed Grant. Principal Investigator 3,000.00 – Jan. 1998 to June 1998. “Gene Therapy for Spinal Fusion with Bone Morphogenetic Protein in a Rodent Model” Sofamor Danek Inc. Industry Research Grant Principal Investigator 10,000.00 – June 1998 to June 1999 “Development of a Novel Spinal Pedicle Screw System for Osteopenic Bone” Synthes, Inc. Industry Research Grant Principal Investigator 11

12 Curriculum Vitae Jeffrey C. Wang, MD 10,000.00 – Jan. 1998 to Jan. 1999 “Regional Gene Therapy for Spinal Fusion:Transformation of Marrow Cells with an Adenoviral Vector to Produce Bone Morphogenetic Protein in a Canine Model” Principal Investigator North American Spine Society Research Grant 20,000.00 – Oct. 1998 to Oct. 2000 “Intrathecal rhBMP-2, -4, -6 After Experimental Cauda Equina Injury in a Rat” National Orthopaedic Fellows Foundation Co-Investigator/Sponsor- 5,000.00 – Nov. 1998 to Nov. 1999 “Demineralized Bone Matrix for Spinal Fusion in an Athymic Rat” Sofamor Danek Inc. Industry Research Grant Principal Investigator 60,000.00 – June 1999 to June 2001 “Regional Gene Therapy for Intradiscal Fusion in a Canine Model” Sofamor Danek Inc. Industry Research Grant Principal Investigator 10,000.00 – July 1999 to July 2001 “Genetic Manipulation of Canine Intervertebral Disc Cells” UCLA Academic Senate Research Grant Principal Investigator 7,000.00 – July 1999 to July 2000 “The Effect of BMP-Producing Marrow Cells Created Via Regional Gene Therapy on Spinal Fusion in a Rat Model” Orthopaedic Research and Education Foundation (OREF) Research Grant and the Musculoskeletal Transplant Foundation Research Grant Principal Investigator 100,000.00 – July 2000 to July 2002. “Minimally Invasive Treatment of Spinal Disorders Using Focused Ultrasonic Fields” The Whitaker Foundation, Biomedical Engineering Research Grant Principal Investigator 218,378.00 – July 2000 to July 2003 “A Comparison of the Osteoinductive Ability of Commercially Available Demineralized Bone Matrix Allografts in the Healing of a Rodent Spinal Fusion” Medtronic-Sofamor Danek, Inc. Research Grant Principal Investigator 12

13 Curriculum Vitae Jeffrey C. Wang, MD 90,000.00 – September 2000 to September 2002 “Gene Activated Matrices with Combination Gene Therapy for Spinal Fusion” Selective Genetics Research Grant Principal Investigator 21,350.00 – December 2000 to December 2002 “Effectiveness Of Miacalcin Nasal Spray In The Treatment Of Pain Due To Osteoporotic Vertebral Compression Fractures” Novartis Co-Principal Investigator 51,271.00 – February 2001 to February 2003 “Prospective Evaluation of Allomatrix Allograft Injectable Putty for Single Level Spine Fusion”. Wright Medical Technology, Inc. Principal Investigator 59,468.00 – February 2001 to February 2003 “Randomized, Single Blind, Multicenter Pilot clinical Trial to Determine the Safety of Oxiplex/SP Gel for the Reduction of Post-Operative Scar Formation”. FzioMed, Inc. Principal Investigator 51,266.25 – April 2001 to April 2002 “Efficacy of Three Different Demineralized Bone Matrices in Inducing an Intertransverse Spinal Fusion in a Rat Model.” Musculoskeletal Transplant Foundation Co-Principal Investigator 108,952.00 – July 2001 to July 2003 “Evalution of Autologous Growth Factors for Spinal Fusion” Interpore Cross International Principal Investigator 20,250.00 – September 2001 to September 2002 “Erythropoetin Administered Perioperatively Compared to the Standard of Care in Blood Conservation in Subjects Undergoing Major Elective Spinal Surgery” Amgen, Inc. 13

14 Curriculum Vitae Jeffrey C. Wang, MD Principal Investigator 118,715.00 – March 2002 to March 2003 A Pilot Study of CELLECT: The Mixing System for Use in Lumbar Fusion Depuy Spine, Inc. Principal Investigator 70,880.000 – Jan. 2003 to Jan. 2005 A Study of Platelet Gels for Spinal Fusion in a Rat Fusion Model Depuy Spine, Inc. Principal Investigator 66,999.00 – June 2003 to June 2006 Evaluation of a Novel Demineralized Bone Matrix for Bone Formation Medtronics Sofamor-Danek Principal Investigator 87,000 – August 2004 to August 2006 Cervical Spine Research Society 2004 Research Grant Award – A Prospective Study of cerebral Cortical Activation of Patients with Cervical Myelopathy Using Functional MRI Co-PI 50,000 – December 2004 UC Discovery Grant: Use of Novel Growth Factor Nell-1 for Spinal Fusion. Principal Investigator 181,453 – Jan 2006 to Jan 2008. Fziomed Grant: Multicenter Clinical Trial to Determine the Safety and Efficacy of Oxiplex/SP Gel for the Reduction of Pain and Symptoms following Lumbar Disc Surgery. Principal Investigator 208,420 – Sept. 2002 to Sept. 2010 Cervical Spine Research Society 2006 Research Grant Award – Bone Morphogenetic Protein Binding Peptides (BBP) as an Adjuvant in Spinal Fusion. Principal Investigator 24,272 – December 2006 Musculoskeletal Transplant Foundation Grant: Combinatorial Approach Using Nell-1, A Novel Bone Growth Factor, and Demineralized Bone Matrix for Accelerated Bone Regeneration. Principal Investigator 125,000 – Jan. 22, 2007 – Jan. 22, 2009 14

15 Curriculum Vitae Jeffrey C. Wang, MD Cervical Spine Research Society 2007 Research Grant Award – The Delphi Trial RCT: International Randomized Clinical Trial of Rheumatoid Craniocervical Treatment Intervention Prognostic Cost-Effectiveness Trial Comparing Early Surgery with Prolonged Conservative Management. Co-PI 25,000 – December 2007. Orthopaedic Research and Education Foundation (OREF) Research Grant– Biologics Registry. PI 38,000 – October 2011 FELLOWSHIP DIRECTOR: Fellows Trained Mark Blechner, MD Donald DeGrange, MD Gerald Alexander, MD Christopher Neuberger, MD David Rogers, MD A. Nick Shamie, MD Robert Boyce, MD Tom Mroz, MD Patrick Suen, MD Eric Wieser, MD Mukund Gundanna, MD Steven Lee, MD Kenneth Lee, MD Thomas Scioscia, MD Gannon Randolph, MD Corey Wallach, MD Andelle, Teng, MD Joseph Kim, MD Scott Daffner, MD Scott McGovern, MD Winston Fong, MD Rahul Basho, MD Alex Gittleman, MD Christopher Wolf, MD Mark Mikhael, MD Beck McAllister, MD Brandon Rebholtz, MD Sandeep Gidvani, MD Connecticut Ventura, CA Fullerton, CA Sacramento, CA Gardena, CA Academic practice, UCLA, Los Angeles, CA Nashville, TN Academic practice, Cleveland Clinic, Cleveland, OH San Jose, CA Dallas, TX College Station, TX Walnut Creek, CA Houston, TX Richmond, VA Arkansas Alexandria, VA Seattle, WA Richmond, VA Academic practice, West Virginia University, Morgantown, WV Maryland Oklahoma City, OK Riverside, CA Santa Monica, CA Wilmington, DE Chicago, IL New Orleans, LA Milwaukee, WI Los Gatos, CA 15

16 Curriculum Vitae Jeffrey C. Wang, MD Babak Khamsi, MD Dmitri Sofianos, MD Riverside, CA Current fellow 16

17 Curriculum Vitae Jeffrey C. Wang, MD BIBLIOGRAPHY Published Articles: 1. Larrick, J.W., Jeffrey C. Wang, B.M. Fendly, D.E. Chenoweth, S.L. Kunkel, and T. Deinhart. Characterization of Murine Monoclonal Antibodies That Recognize Neutralizing Epitopes on Human C5a. Infection and Immunity, August 1987; 55:1867-1872. 2. Larrick, J.W., O.Gray, T.Deinhart, Jeffrey C. Wang, J. Flatgaard, and K.T. Chong. Generation of a Protective Human Monoclonal for the Treatment of Gram-Negative Sepsis. Progress in Clinical and Biological Research, 1988; 272:383-393. 3. Hatherhill, J.R., K.E.Stephens, K.Nagao, A. Ishizaka, L.Wilmarth, Jeffrey C. Wang, T.Deinhart, J.W.Larrick, and T.A. Raffin. Effects of Anti-C5a Antibodies on Human Polymorphonuclear Leukocyte Function: Chemotaxis, Chemiluminescence, and Lysosomal Enzyme Release. Journal of Biological Response Modifiers, 1989; 8:614-624. 4. Matthew S. Shapiro, M.D. and Jeffrey C. Wang, M.D. Elbow Fractures: Treating to Avoid Complications, The Physician and Sports Medicine, Vol. 23:4, pp. 39-50, April 1995. 5. Jeffrey C. Wang, M.D. and Matthew S. Shapiro, M.D. Pellegrini-Steida Syndrome, The American Journal of Orthopaedic Surgery, Vol.24:6, pp. 493-497, June 1995. 6. Jeffrey C. Wang, M.D. and Matthew S. Shapiro. Changes in Acromial Morphology with Age. Journal of Shoulder and Elbow Surgery, Jan/Feb1997;6:55-59. 7. Jeffrey C. Wang, M.D., Harvinder S. Sandhu, M.D., Warren D. Yu, M.D., Joe T. Minchew, M.D., Rick B. Delamarter, M.D. MRI Parameters for Imaging Titanium Spinal Instrumentation, Journal of Spinal Disorders, Vol.10(1), pp.27-32, 1997. 8. Jeffrey C. Wang, M.D., Warren D. Yu, M.D., Harvinder S. Sandhu, M.D.,Vivian Tan, B.S., Rick B. Delamarter, M.D. A Comparison of MRI and CT Image Quality after the Implantation of Tantalum and Titanium Spinal Instrumentation. Spine, Vol.23(15):1684-1688, Aug.1998. 9. Jeffrey C. Wang, M.D., D. Zou, M.D., Hansen Yuan, M.D., Jung Yoo, M.D. A Biomechanical Evaluation of Graft Loading Characteristics for Anterior Cervical Discectomy and Fusion: A Comparison of Traditional and Reverse Grafting Techniques. Spine, Vol.23(22):2450-2454, Nov. 1998. 10. Jeffrey C. Wang, M.D., Henry H. Bohlman, M.D., K. Daniel Riew, M.D. Dural Tears Secondary to Lumbar Spine Surgery: Management and Long-Term Results in Eighty-Eight Patients. The Journal of Bone and Joint Surgery, Vol.80A(12):1728-1732, Dec.1998. 11. Jeffrey C. Wang, M.D., Stephen Yoo, B.S., Rick B. Delamarter, M.D. The Publication Rates of presentations at Major Spine Specialty Society Meetings. Spine, Vol.24(5):425-427, 1999. 12. Jeffrey C. Wang, M.D, Matthew S. Shapiro, M.D., Joshua D. Hatch, M.D., Jason Knight, B.S., Frederick J. Dorey, Ph.D., Rick B. Delamarter, M.D. The Outcome of Lumbar Discectomy in Elite Athletes. Spine 1999, Vol.24(6):570-573. 13. Jeffrey C. Wang, M.D., Warren D. Yu, M.D., Harvinder S. Sandhu, M.D., Sunita Bhuta, M.D., Foster Betts, Ph.D., Rick B. Delarmarter. Metal Debris from Titanium Spinal Instrumentation. Spine 1999,Vol 24(9):899-903. 17

18 Curriculum Vitae Jeffrey C. Wang, MD 14. Duerinckx, AJ; Yu, WD; El-Saden, S; Kim, D; Jeffrey C. Wang, M.D.; Sandhu, HS. MR imaging of cervical spine motion with HASTE. Magnetic Resonance Imaging, 1999 Apr, 17(3):371-81. 15. Jeffrey C. Wang, M.D., Joshua D. Hatch, M.D., Rick B. Delamarter, M.D., and Harvinder S. Sandhu, M.D. The Diagnostic Value of Cervical Flexion and Extension Radiographs in Acutely Injured Patients. Clinical Orthopaedics and Related Research, 1999 Aug, 364:111-116. 16. Jeffrey C. Wang, M.D., Paul W. McDonough, M.D., Kevin K. Endow, B.S., Linda E.A. Kanim, B.A., Rick B. Delamarter, M.D. The Effect of Cervical Plating on Single-Level Anterior Cervical Discectomy and Fusion. Journal of Spinal Disorders, 1999, 12(6):467-471. 17. Jeffrey C. Wang, M.D., Paul W. McDonough, M.D., Kevin K. Endow, B.S., Rick B. Delamarter, M.D. Increased Fusion Rates with Cervical Plating for Two-level Anterior Cervical Discectomy and Fusion. Spine, 2000, Vol 25(1):41-45. 18. Jeffrey C. Wang, M.D., Gregory Horner, M.D., Eric D. Brown, M.D., Matthew S. Shapiro, M.D. The Relationship Between Acromial Morphology and Conservative Treatment of Patients with Impingement Syndrome. Orthopaedics, 2000, Vol 23(6):557-559. 19. Anthony A. Scaduto, M.D. and Jeffrey C. Wang, M.D. Gene Therapy Applications for Lumbar Fusion Surgery. Operative Techniques in Orthopaedics, Oct. 2000, Vol.10(4):325-331. 20. Jeffrey C.

Jeffrey C. Wang, MD 4 4 ACADEMIC APPOINTMENTS: Professor of USC Orthopaedic Surgery 2013 - present Professor of USC Neurosurgery Chief, USC Orthopaedic Spine Service Co-Director, USC Spine Center Keck School of Medicine at USC Univeristy of Southern California Acting Chairman, UCLA Department of Orthopaedic Surgery 2010 - Sept. 23-26

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