Bridges In Life Sciences 9th Annual Scientific Conference .
Bridges in Life Sciences 9th AnnualScientific ConferenceSplit, CroatiaMay 27 – June 1, 20140
Table of ContentsOrganizing Committee3Conference Venue4RECOOP HST Association5Cedars – RECOOP Research Centers8Croatian Medical Journal12Preconference Workshop – “Protect and Publish”13Agenda of the Bridges in Life Sciences 9th Conference20Abstracts34Plenary Session May 30: 9:00 – 10:3035Poster Session May 30: 10:30 - 12:0036Plenary Session May 30: 11:00 – 12:3042Plenary Session May 30: 14:00 – 16:0050Poster Session May 30: 16:00 - 18:0057RECOOP HST Association General Assembly72Plenary Session May 30: 18:00 – 19:3073Plenary Session May 31: 8:30 – 10:1580Poster Session May 31: 10:30 - 11:3087Plenary Session May 31: 11:30 – 12:3097Plenary Session – RECOOP REVIEW May 31: 14:00 – 15:00103Research Networks’ Breakaway sessions May 31: 15:00 - 16:00117Closing Poster Session May 31: 16:00 - 18:30118Plenary Session – Closing Remarks May 31: 18:30 - 19:301335th RECOOP TriNet Meeting134RECOOP Visegrad Scholarship Program135Split Information Package137Conference Participants1431
Organizing CommitteeUSA - Cedars-Sinai Medical Center, Los Angeles, CaliforniaEdward PrunchunasSenior Vice President for Finance and Chief Financial Officer, Cedars-Sinai Medical Center& Chairman of the Supervisory Board of the RECOOP HST AssociationShlomo Melmed, MDSenior Vice President, Academic Affairs, Dean of the Medical Faculty, Cedars-Sinai MedicalCenterSandor G. Vari, MDDirector, International Research and Innovation Management Program, Cedars-Sinai MedicalCenter & President of the RECOOP HST AssociationArora ChanderChander P. Arora, PhDResearch Project Adviser, International Research and Innovation Management Program,Cedars-Sinai Medical Center & Research Project Management of the RECOOP HSTAssociationCroatiaProf. Livia Puljak, MD, PhDAssociate Professor, Department of Anatomy, Histology and Embryology, University of SplitSchool of Medicine, Split, CroatiaProf. Ana Marusic, MD, PhDChair, Department of Research in Biomedicine and Health, University of Split School ofMedicine, Split, Croatia & Co-editor in Chief, Journal of Global Health, www.jogh.orgProf. Marija Heffer, MD, PhDProfessor, Department of Medical Biology, Josip Juraj Strossmayer University of Osijek,School of Medicine, Osijek, CroatiaISBN 978-963-08-9491-32
Preconference Workshop – „Protect and Publish“Venue: HOTEL DUJAMMay 27 – 29, 2014Bridges in Life Sciences 9th Annual Scientific Conference in Split, CroatiaVenue: ATRIUM HOTELMay 30 – 31, 2014Hotel AccommodationHOTEL DUJAM *** & YOUTH HOSTEL, Velebitska 27, 21000 Split – CroatiaPhone: 385 (0) 21/273-080; www.hoteldujam.comBEST WESTERN Hotel Art ****, UlicaSlobode 41, 21000 Split, CroatiaPhone: 385 (0)21 302-302; http://www.bestwestern.com/ATRIUM HOTEL ****** Domovinskog rata 49a, 21000 Split, CroatiaPhone: 385 21 200 000; www.hotel-atrium.hr3
The Association for Regional Cooperation in the Fields of Health, Science andTechnology (RECOOP HST)Short Name: RECOOP HST Association1.IntroductionIn 2006 Cedars–Sinai Medical Center (CSMC) with eleven CEE universities and academicorganizations from six countries (Croatia, Czech Republic, Hungary, Romania, SlovakRepublic and Ukraine) formed the Regional Cooperation for Health, Science and Technology(RECOOP HST) Association.In 2012 CSMC converted the Association into the Association for Regional Cooperation inthe Fields of Health, Science and Technology which was registered by the Court of Debrecenin Hungary under the registry number 4160 on May 10, 2012, TAX ID: 18299140-1-09.Members of the Association constituted from 8 countries (Croatia, Czech Republic,Denmark, Hungary, Romania, Slovak Republic, Ukraine and USA) and 14 higher educationor research organizations.Members of the RECOOP HST Association:1. Cedars-Sinai Medical Center, Los Angeles, USA2. Josip Juraj Strossmayer University of Osijek, School of Medicine, Osijek, Croatia3. IKEM - Institute for Clinical and Experimental Medicine, Prague, Czech Republic4. Institute of Macromolecular Chemistry, Academy of Sciences, Czech Republic5. Faculty of Military Health Sciences, University of Defense, Hradec Kralove, CzechRepublic6. Faculty of Pharmacy, University of Copenhagen, Denmark7. University of Debrecen, Hungary8. University of Pecs, Hungary9. University of Szeged, Hungary10. Carol Davila University of Medicine and Pharmacy, Bucharest, Romania11. Slovak Medical University, Bratislava, Slovak Republic12. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev,Ukraine13. Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine14. Danylo Halytsky Lviv National Medical University, Lviv, Ukraine4
2.International Partnerships of CSMC RECOOP HST AssociationWorld Health Organization (WHO)RECOOP HST Mother and Child Health Network was one of the partners of the InternationalPREterm BIrth Collaborative (PREBIC; www.prebic.net) of the World Health Organization,Department of Reproductive Health and Research World Intellectual Property Organization (WIPO)Beside research opportunities the RECOOP Association inspires young scientists and clinicalresearchers for creative thinking, and helps to learn how to make decision on “publish anddisclose” or “protect and publish”. The Association is working with the World IntellectualProperty Organization (WIPO; http://www.wipo.int) to train faculty members, managers,young scientists, clinicians and PhD students for innovation management and technologytransfer from the RECOOP HST Association. The members of the participating organizationsare taking the WIPO World Wide Academy (WWA) Distance Learning (DL) courses anduntil 2011 more than 500 faculty members were trained from the Association.National Institutes of Health (NIH)The first “Bridges in Life Sciences” regional networking meeting was organized in October2003 by Cedars-Sinai Medical Center (CSMC) with four Hungarian Universities along withthe Fogarty International Center (FIC) at the National Institutes of Health (NIH) in Budapest,Hungary.On June 4, 2008 the representative of the RECOOP Association met with the representativesof the Division of International Relations, John E. Fogarty International Center for AdvancedStudy in Health Sciences, NIH, DHHS, USA and agreed to continue the “Bridges in LifeSciences” regional networking meeting organized in October 2003.The 4th Annual Scientific Meeting took place in Debrecen, Hungary on April 4 – 5, 2009with the Visegrad Group’s (V4) academic organizations and NIH funded PIs from the USAwith robust collaborative works in the Central and Eastern Europe (CEE) Countries. The hostorganization University of Debrecen on the behalf of the Association applied for a StandardGrant and CSMC provided the matching fund. The Bridges in Life Sciences US - CEERegional Networking Meeting provided opportunity for 60 CEE RECOOP young scientistsselected from the submitted 100 abstracts by the Scientific Advisory Board of the RECOOPAssociation and additional 20 young Ukrainian scientists were selected for the YoungScientists Forum with the support of California Association to Aid Ukraine (CAAU).The U.S. Government Global Health InitiativeMs. Lois Quam, Executive Director of U.S. Government Global Health Initiative, U.S.Department of State in her letter sent to the Bridges of Life Sciences 7th Annual Conferencerecognized the RECOOP HST Association Networks’ research activities as valuable assets ofGlobal Health Initiative.Visegrád Group (V4)From 2008 the members of the RECOOP HST Association with the financial support ofCedars – Sinai Medical Center applied for 20 Standard Grants and won 14, also one StrategicGrant.5
During the last four years the RECOOP HST Association won 14 Standard Grants(20810243, 20820016, 20820040, 20820041, 20910138, 20920001, 20920002, 20920023,20920024, 20910138, 21010083, 21010070, 21020052, and 21110096) to support theformation and management of research networks and multinational - multidisciplinaryresearch projects.Also the IVF Standard Grants helped to build support networks for Biosafety andBiosecurity, Animal use in Research, Clinical Research Management, Research andInnovation Management Training.Creation of the RECOOP Life Science Research Platform was sponsored by theInternational Visegrad Fund Strategic Grant (31110035) “Future of Visegrad FourFamilies Depends on Healthy Women and Children”.The last five years IVF and CSMC-RECOOP extended activities toward the EU EasternPartnership, the Visegrad Western Balkans and the RECOOP HST Association is buildingbridges to United States Global Health Initiative.The IVF grants won by CSMC – RECOOP also helped the International Visegrad Fund tomove toward to the 21st Century and broaden the scope of funded activities in the VisegradGroup to involve more young scientists into the new biotechnology developments, couldcreate innovative ideas, new medical treatment modalities and jobs in the region.3. Research Capacity BuildingThe RECOOP HST Association’s main goal is to enhance research collaboration and provideplatforms for scientific networking in life sciences within the Visegrad Four Countries,Central - Eastern Europe, and Western Balkan. The research priority of the Association iswomen's and children’s health in the Visegrad Four European Macro-Region (CzechRepublic, Hungary, Poland and Slovak Republic) and the neighboring countries (Belarus,Bosnia and Herzegovina, Croatia, Moldova, Macedonia, Montenegro, Romania, Serbia andUkraine). The Association paves the way toward GLOBAL Research Programs of theNational Institutes of Health, the World Health Organization and private funds (Gates,Clinton).In the last six years the RECOOP HST Association implemented translational and retro/prospective clinical research in the Mother and Child Health (M&CH), the Women’s Healthand Cardiovascular Diseases (WH&CVD) and in the NanoBioTechnology (NBT) ResearchNetworks.The Mother and Child Health and the Women’s Health and Cardiovascular Diseases retroand prospective clinical research studies are using web based electronic data entry forms(EDEF; http://www.flexiform.eu/).Beside the management of research networks for multinational - multidisciplinary researchprojects, the RECOOP HST Association also built support networks for Biosafety andBiosecurity, Animal use in Research, Clinical Research Management, Research andInnovation Management Training.6
In the RECOOP Research Networks 147 scientists are working in 18 research projects inclinical, basic and translational research studies to investigate biological pathways leading togender differences in cardiovascular diseases, preterm birth, breast, cervical and braintumors.In 2012 the RECOOP HST Association integrated the multidisciplinary, multicenter researchstudies of the RECOOP Research Networks into the RECOOP Life Science ResearchPlatform and formed 18 CSMC RECOOP Research Centers (CRRC) from 7 countries(Croatia, Czech Republic, Hungary, Poland, Romania, Slovak Republic, and Ukraine)working on translational and clinical research in the field of Genomics - Proteomics,Epigenetics, Metagenomics, Molecular Biology, Metabolomics and NanoBioTechnology.The CSMC - RECOOP Research Centers (CRRC):Cardiovascular Disease and Women’s Health:Lifestyle intervention in women’s cardiovascular health with different reproductive andrisk factorsJan Pitha MD, PhD, Head of Laboratory for Atherosclerosis Research Department ofCardiology, IKEM - Institute for Clinical and Experimental Medicine, Prague, CzechRepublicMyocardial contractile dysfunctionAttila Borbely, MD, PhD, Cardiologist, Institute of Cardiology, Medical and HealthScience Center, University of Debrecen, HungaryThe role of myofilamentary protein changes in diastolic dysfunction of newbornsZoltan Papp, MD, PhD, DSc, Institute of Cardiology, Clinical Physiology Department,University of Debrecen, HungaryObesity, bone density and cardiovascular diseasesProf. Martin Gajdoš, MD, PhD and Dr. Zora Krivosikova, PhD Medical Faculty,Department. of Clinical and Experimental Pharmacotherapy, Slovak MedicalUniversity, Bratislava, Slovak RepublicObesity, stress and cardiovascular functionProf. Marija Heffer MD, PhD, Department of Medical Biology, Josip Juraj StrossmayerUniversity of Osijek, School of Medicine, Osijek, Croatia7
Oxidative stress markers for metabolic and cardiovascular diseasesProf. Elizabeta Has-Schön, PhD, Department of Biology, Josip Juraj StrossmayerUniversity of Osijek, School of Medicine, Osijek, CroatiaRole of semicarbazide sensitive amine oxidase (SSAO) in Cardiovascular Diseases(endothelial cells and/or adipocytes)Prof. Éva Szökő, PhD, DSc, Department of Pharmacodynamics, Faculty of Pharmacy,Semmelweis UniversityVitamin D deficiency and effect on neurotransmitters in diabetes, ischemic heartdisease and preterm birthTatiana Borisova, Department of Neurochemistry, Palladin Institute of BiochemistryNAS of UkraineGlycosylation and BioseparationProf. András Guttman, PhD, DSc, MHAS, Research Centre for Molecular Medicine,Horváth Laboratory of Bioseparation Sciences, Medical and Health Science Center,University of Debrecen, HungaryMother and Child Health:Iron intake and preterm birthChander P. Arora, PhD, Cedars-Sinai Medical Center International Research andInnovation Management Program, Los Angeles, CA, USACervical fluid IL-6 - a possible predictor of early onset sepsis in pregnanciescomplicated by late PPROMMarian Kacerovsky, MD, PhD, Department of Obstetrics and Gynecology, UniversityHospital in Hradec Kralove, Czech RepublicAnimal models to study preterm birthProf. Gyorgy Falkay, PhD, DSc. & Robert Gaspar, PhD Department ofPharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged,HungaryEnterovirus infection in mother, neonate, infants and follow up in child developmentProf. Shubhada Bopegamage, PhD, Entervirus Laboratory, Virology Department,Slovak Medical University, Bratislava, Slovak RepublicScreening mothers and newborns for cytomegalovirus infectionWilliam J. Britt, MD, University of Alabama- Birmingham, Alabama, USA and IulianaCeausu, MD, PhD, the Department of Obstetrics and Gynecology of “Dr. I.Cantacuzino” Hospital, “Carol Davila” University of Medicine and Pharmacy,Bucharest, Romania8
NanoBioTech and Cancer:Iron nanoparticles for monitoring different diseases, (regenerative medicine,cardiovascular and cancer)Prof. Daniel Horák, PhD Department of Polymer Particles, Institute of MacromolecularChemistry, Academy of Sciences, Prague, Czech RepublicTatiana Borisova, PhD, DSc, Head, Department of Neurochemistry, Palladin Institute ofBiochemistry, National Academy of Sciences of Ukraine, Kiyv, UkraineBiofunctionalization of nanoparticles and targeted drug delivery studies,Prof. Rostyslav Stoika, PhD, DSc, Department of Regulation of Cell Proliferation andApoptosis, Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv,UkraineTargeted drug delivery for cancer treatmentProfessor Roman Bogdanovych Lesyk, PhD, D. Sc, Department of Pharmaceutical,Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National MedicalUniversity, Lviv UkraineTunable nanocrystals for biomedical imagingArtur Podhorodecki, PhD Institute of Physics, Wroclaw University of Technology,Wroclaw, PolandIn vitro and in vivo immune assays for evaluation of immunotoxic effect ofnanoparticlesJana Tulinska, MD, PhD. Laboratory of Immunotoxicology, Slovak MedicalUniversity, Bratislava, Slovak RepublicThe participating CRRCs from the member universities and research organizationsimplemented research programs for Medical and PhD Students.RECOOP Life Science Research Platform already realized short term (1-2 years) pilotresearch studies. The Networks continue the translational and clinical research studies inmidterm (5 years), and the RECOOP HST Life Science Research Platform shall plan tocontinue the clinical research studies for minimum 20 - 30 years and follow up the women,men and newborns registered in the Electronic Data Entry Forms (EDEF) started in 2011.The Association inspires young scientists and clinical researchers for creative thinking, andhelps to learn how to make decision on “publish and disclose” or “protect and publish”.RECOOP provides training for young scientists to learn proper and scientifically soundcommunication of their research results in their manuscripts and presentation. TheAssociation provides practical training on the presentation of data in the manuscript from the“Introduction, Methods, Results and Discussion” to the “Conclusion” sections of themanuscript and guides the young scientists how to organize data in tables and graphs,presenting results of statistical analysis.The RECOOP HST Association organizes annually the Bridges in Life Sciences Conferencesto review the scientific progress in the Association. During the Bridges in Life SciencesAnnual Meeting the Scientific Advisory Board selects the top ten young scientists.9
The RECOOP scientific works were published in the Annual Scientific Review Journal theBiopolymers and Cell (www.biopolymers.org.ua) 2010. Vol. 26. N 2 & N 2 supplementary;2011. Vol. 27. N 2 & N 2 Supplementary; 2012. Vol. 28. N 2 supplementary and 2013.Vol.29. N2 supplementary.The winner gets the Cedars-Sinai RECOOP Scholar Grant to visit Los Angeles for two weekswith her/his supervisor. They are visiting research groups and laboratories and presentingtheir scientific work during research seminars.The top ten young scientists selected during the Bridges in Life Sciences Annual Conferenceshave the opportunity to apply for International Visegrad Fund (IVF) Scholarship and receivethe RECOOP Young Scientists Matching Fund. The Visegrad Scholarship is the VisegradFour European Macro-Region’s Fulbright Program. Therefore it could be important to linkthe Visegrad Scholarship and the Fulbright Foreign Student Program.CSMC – RECOOP Research Centers (CRRC) are the Center of Excellences of the RECOOPHST Association. They host young scientists, PhD students with CSMC – RECOOP (IVF –CSMC - RECOOP) Scholarship. The RECOOP HST Association Scientific Advisory Boardselects the young scientists could apply for IVF – CSMC - RECOOP Scholarship.The selected young scientists (preferably PhD students) will spend maximum four semestersand receive: 2,300 / semester and the corresponding host universities/institutes receive 1,500/semester/scholar. The host CRRC will get 1,000 for laboratory expense andconsumables from CSMC – RECOOP HST Association.RECOOP activities compliment the U.S. Government’s commitment to the Global HealthInitiative “the way U.S. Government agencies conduct global health activities, building onsuccessful bipartisan leadership in global health and expanding their impact for sustainableresults around the world.”“The RECOOP HST Association explores and enhances LOCAL scientific outputs of thepartner organizations, creates critical mass of scientifically sound innovative research atREGIONAL level and exploits the research outcomes at GLOBAL level to improve theprevention and treatment of major public health problems.”TMThe RECOOP Research Networks could be a model for geographical regions have lingual,cultural, historical, economic and political common ground worldwide in regions in Africa,Asia, North and South America to improve women’s and children’s health.Dr. Sandor G. Vari, MDDirector, International Research andInnovation Management ProgramCedars-Sinai Medical Center &President of the RECOOP HST Association6420 Wilshire Blvd., Ste. 300, Los AngelesCA 90048-5502, USAOffice 1: 1 323-866-8122; 1 323-866 -6824Office 2: 1 818 904 1954Mob: 1 818 398-2642E-mail: vari@cshs.org10
The Croatian Medical Journal (June 2014, www.cmj.hr) published thematic issuededicated to the RECOOP Bridges 9th Annual Scientific Conference in Split, Croatia.The mission of Croatian Medical Journal (CMJ) was
Study in Health Sciences, NIH, DHHS, USA and agreed to continue the “Bridges in Life Sciences” regional networking meeting organized in October 2003. The 4th Annual Scientific Meeting took place in Debrecen, Hungary on April 4 – 5, 2009 with the Visegrad Group’s (V
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Siklus akuntansi pendidikan merupakan sistematika pencatatan transaksi keuangan, peringkasan dan pelaporan keuangan. Menurut Bastian (2007) siklus akuntansi pendidikan dapat dikelompokkan menjadi 3 tahap, yaitu: 1. Tahap Pencatatan a. Mengidentifikasi dan mengukur bukti transaksi serta bukti pencatatan. b. Mengelola dan mencatat bukti transaksi seperti kwitansi, cek, bilyet giro, nota kontan .
