16390 16400 16410 16420 16430 16440 FBI A1 (L15997) Roche (F15975) HV1 16093 16126 16129 HVI C-stretch Roche IA Roche ID Roche IE Roche IC HV1 FBI B1 (H16391) Roche (R16418) Hypervariable Region I 16024-16365 342 bp examined SSO Probes 16093 16126 16129

Left: Clinical chemistry analyzer Roche ELECSYS 2010 und Roche Hitachi 917. Right: Clinical chemistry analyzer Roche Hitachi 717. Central laboratory - . Right: Coagulation analyzer Sigma AMAX (special analyzes). Clotting laboratory -

Michael Crowley, Head of Business Development Roche Research & Early Development, Pharma Partnering Roche Company Presentation. 2 The Roche Group: an innovation-driven company Why we make a good partner What we are looking for from you. 3 What we are looking The Roche Group: an for from you

Roche und der Geschäftsleitung der Roche in Verhandlungen mit dem AVR erarbeitet worden. und gelten für folgende Roche-Gesellschaften, inkl. ihrer Zweigniederlassungen in der Schweiz: . – Individuelle Leistungen und Beiträge zum Erfolg von Roche werden vom Arbeitgeb

Investor Update F. Hoffmann-La Roche Ltd 4070 Basel Switzerland Investor Relations email: investor.relations@roche.com Tel. 41 61 68-88880 Fax 41 61 69-10014 www.roche.com 1/11 Basel, 30 January 2020 Roche reports very strong results in 2019 1Group sales increase 9% at constant exchange rates and 8% in Swiss francs, driven by new products,

1 Coagulation and Rapid Mixing Coagulation is the process by which particles become destabilized and begin to clump together. Coagulation

incorporate coagulation monitoring for perioperative hemostatic management? Transfusion choices Perioperative coagulation monitoring is beneficial only if the results contribute to clinically effective decisions. Patients with similar conditions may receive different treatments if protocols and triggers for coagulation management are not in place.

The cobas t 711 coagulation analyser can also be connected with the cobas 8100 and the cobas connection modules. Both analysers can be used in rand om-access or batch modes, and offer true STAT capabilities, with dedica ted slots for urgen t samples. cobas t 511 coagulation analyzer

cobas t 411 coagulation analyzer 5.478 3.261 1 cobas t 511 coagulation analyzer 8.757 4.413 1 cobas t 711 coagulation analyzer 11.855 5.973 1 MultiplateT analyzer 1.310 – – – Urindiagnostik cobas u 601 urine analyzer 4.989 – – – cobas

Identify solutions in areas of coagulation that can be enhanced by implementing good laboratory practices and standard operating procedures Analyze real case studies and how to troubleshoot testing to determine root cause and what steps to prevent reoccurrence. Enhance general knowledge of coagulation, standards and methods.

Source of Saturn’s Rings The moon’s own gravity tends to hold it together. Tidal forces from planet tend to pull it apart The “Roche Limit” is the critical distance where the two balance Saturn’s moons are (mostly) outside of Roche Limit Saturn’s rings are (mostly) inside the Roche limit. Roche Limit (2.4 Saturn .

The court also received evidence from Ms Maria Roche. Ms Roche is the Tumut Cluster Manager for Murrumbidgee Local Health District. As at 1 January 2016, Ms Roche was the Acting Rural Group Manager for the Riverina Group, which included Tumut Health Service. She had been in that role since 2013. Ms Roche gave oral evidence but also provided four

and act according to the Roche mission statement. The work of our employees affects the life of patients worldwide, from prevention through to medicinal products. They share their knowledge between the Pharma and Diagnostics Divisions, as well as worldwide within the Roche Group. This requires courage and vision, tackling of problems, and an

COAGULATION TESTING ON ROTEM The basic principles and technical aspects of TEG and ROTEM have been reviewed elsewhere.14,38-40 In this article, the practical applications of ROTEM are described because this system currently offers comprehensive tests of coagulation. For standard ROTEM measurements, a citrated whole-blood sam-

and adding ozone and irradiating with ultraviolet light. 1.2.2 Coagulation. In wastewater treatment operations, the processes of coagulation and flocculation are employed to separate suspended solids from water. Although the terms coagulation and floccu

score, and CT characteristics have been routinely used to predict outcome in patients with TBI [15]. Although coagulation abnormalities may be a better predictor of mortality than the absence of the bilateral pupillary light reflex in some patients [16], prognosis is rarely predicted by coagulation status alone in the clinical setting.

Sysmex Automated Blood Coagulation Analyzer CS-2500 I. Device Description: Sysmex CS-2500 The Sysmex Automated Blood Coagulation Analyzer CS-2500 (hereafter Sysmex CS-2500) is an automated blood coagulation instrument which analyzes samples collected in 3.2% sodium citrate using clotting, chromogenic and immunoassay methods. Results are .

Principles of Blood Coagulation Amplification Modified from Dahlbäck, Blood 2008 1, multiple linked enzymatic reactions 2, enzyme-cofactor complexes 3, surface localization 4, feed-back activation 5, coagulation factor concentrations increasing in pathway

of activator augments the contact activation phase of coagulation, which stimulates the intrinsic coagulation pathway. ACT can be performed manually, whereby the operator measures the time interval from when blood is injected into the test tube to when clot is seen along the sides of the tube. More commonly, the ACT is automated

ASTM D2996 or ASTM D2997 ASTM D2996 or ASTM D2997 (1) No hydrostatic test required (2) Dimensional tolerances only Unless otherwise tested and approved by the Department, only use encasement pipe or uncased carrier pipe material that is new and has smooth interior and exterior walls. When the Plans show that the casing is to be used as a drainage carrier pipe, extend the casing the entire .