M.Sc. Option In Molecular And Cellular Medicine

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Direction des affaires académiquesM.Sc. option in Molecular and Cellular MedicineMolecular Biology Programs at the Faculty of MedicineUniversity of MontrealSummaryCycleGraduate Cycles (2nd cycle)RankMaster of Science (MSc)Credits45 creditsDuration1 year (three terms)Education planFull time, with day classes andinternshipsOpen to international studentsAdmission termAdmission in the fall onlyLocationClinical Research Institute ofMontreal (IRCM)110, avenue des Pins OuestContact person for program informationMyrna Khuon, Program Coordinator514 987-5716 mcm@ircm.qc.caPresentationWith the objective of meeting emerging needs, the Institut de recherches cliniques de Montréal (IRCM) hasdeveloped the Master's degree option in cellular and molecular medicine (MCM) to train a new generation ofscientists with in-depth knowledge of molecular biology, who are also aware of a global vision of the study ofhuman diseases.This unique and innovative program is affiliated with the molecular biology programs of the Faculty of Medicineof the Université de Montréal.ircm.qc.ca/mcm1

Option de maîtrise en médecine cellulaire et moléculaire IRCMProgram Strengths Accelerated progress in one year allowing a gateway to the PhD without writing a thesis;Two intensive four-month internships (32 credits) in two different IRCM laboratories;Experience on different IRCM technological platforms (bioinformatics, genomics, proteomics, flowcytometry, imaging and microscopy, animal models);Exposure to different aspects of clinical research in courses given by clinician-researchers.General objectives To train versatile graduate students who will have a broad vision of biomedical research;Provide unique translational research training to align fundamental research with clinical practice needs;To train a new generation of scientists mastering the new technologies of fundamental research;Provide quality intensive training, allowing students to validate their interest in medical research andadequately prepare them for postgraduate studiesStructure and curriculumThe option has a specific course curriculum, including 45 credits distributed over a one-year period (threeterms): five mandatory courses (12 credits), two laboratory internships with report writing (32 credits) and aresearch seminar (1 credit).FallCourseBIM 6073BIM 6026TitleTranslational research practiceMolecular and cellular biology 1Credits5 cr.2 cr.WinterCourseBIM 6075ABIM 6028MMD 6005RBIM 6035TitleInternship with report 1Molecular and cellular biology 2Ethics and Health ResearchResearch seminar 1.1Credits16 cr.2 cr.1 cr.--SummerCourseBIM 6075BBIM 6074BIM 6035TitleInternship with report 1Translational medicine practiceResearch seminar 1.2Credits16 cr.2 cr.1 cr.ircm.qc.ca/mcm2

Option de maîtrise en médecine cellulaire et moléculaire IRCMSince the IRCM is a bilingual environment and the MCM option welcomes students from around the world, thevast majority of courses are taught in English. However, since this option is offered by the Université deMontréal, all assignments and exams can also be written in French.Funding and scholarshipsAt the IRCM, all students selected for the MCM Master's option receive an annual scholarship of 20,000(Bombardier-Molson Scholarship).Students, supported by members of the academic affairs department, are also encouraged to apply to variousexternal scholarships competitions.Many scholarships are offered by the Faculty of Graduate and Postdoctoral Studies (FESP) and the Faculty ofMedicine of the Université de Montréal such as : Bourse d’exemption des droits supplémentaires de scolarité pour étudiants internationaux (C)Bourse de MÉRITE aux cycles supérieursBourse d'excellence de la Faculté des études supérieures et postdoctoralesOther scholarships from granting agencies are also available to facilitate graduate studies, including: Canadian Institutes of Health Research (CIHR)Natural Sciences and Engineering Research Council (NSERC)Canada Research Chairs (CRC)Fonds de recherche du Québec - Santé (FRQS)Fonds de recherche du Québec - Nature et technologies (FRQNT)Admission and requirementsCandidates for the Master's degree option in molecular and cellular medicine are recruited directly by theIRCM's Academic Affairs department.Admission requirements You must have successfully completed or be enrolled in a bachelor's degree or master's degreeprogram in a relevant discipline (biochemistry, biology, microbiology, chemistry); or hold a medicaldegree with a right to practice in Canada or Quebec; and have significant experience in basic research.You must have maintained a minimum cumulative average of 3.0 out of 4.3 (70%, B, 12 out of 20, orequivalent).Meet the general eligibility requirements (section XI) of the Faculty of Graduate and Postdoctoral StudiesPedagogical Regulations.ircm.qc.ca/mcm3

Option de maîtrise en médecine cellulaire et moléculaire IRCMApplication process1.Fill in this online form. The form must include your resume, university transcripts and a motivation letter(700 words).2.Ask a letter of recommendation from someone who can assess your ability to pursue a career inbiomedical research. This should be sent by e-mail directly from the author to mcm@ircm.qc.ca.3.Selected candidates will be interviewed by the MCM option selection committee.4.Selected candidates must then submit an application to the registrar's office of Université de Montréal.Application to certain scholarships may also be required for students outside Quebec.Evaluation of applicationsApplications are evaluated by a selection committee composed of IRCM researchers. Candidates are selectedprimarily on the basis of academic record, biomedical research experience and motivation to pursue graduatestudies.Application deadlinesStudent Status Quebec students: from January 1 to May 31 Canadian, non-Quebec resident: from January 1 to April 1* French and Belgium (francophone): from January 1 to May 1 International: from January 1 to April 1** These deadlines may differ. For the exact date, contact the academic affairs direction via the following emailaddress: mcm@ircm.qc.caSubmit an applicationircm.qc.ca/mcm4

Option de maîtrise en médecine cellulaire et moléculaire IRCMAccelerated transition to a PhDThe PhD in Molecular Biology, option in Cellular and Molecular Medicine, is a continuation of the trainingof the Master's option in MCM. Offered at the IRCM, it provides students with multidisciplinary training inmolecular biology with an emphasis on the latest technologies used in fundamental and translationalresearch. The research themes in MDC are mainly focused on the study of human diseases.Doctoral training requires the selection of a research director at the beginning of the program.For a description of the MDC doctoral program, visit the IRCM website.ircm.qc.ca/mcm5

Option de maîtrise en médecine cellulaire et moléculaire IRCMIndex of pedagogical activities of the curriculumBIM 6026 – Molecular and cellular biology 1Graduate Cycles 2 credits Fall termUnderstanding of basic molecular mechanisms and cellular structures. Molecular analysis of complex systems(immunology, neurobiology, developmental biology).BIM 6028 – Molecular and cellular biology 2Graduate Cycles 2 credits Winter termUnderstanding of basic molecular mechanisms and cellular structures. Molecular analysis of complex systems(immunology, neurobiology, developmental biology).BIM 6035 – Research seminarGraduate Cycles 1 credit Winter and summer termsTeach the student to synthesize their research, present orally and discuss their project. The student is requiredto participate in the presentations of other students.BIM 6073 – Translational research practiceGraduate Cycles 5 credits Fall termCOURSE OFFERED EXCLUSIVELY TO STUDENTS OF THE MASTER'S DEGREE OPTION IN MCMPractical and theoretical training modules on the use of advanced technological platforms in molecular biologyand biomedical research; use of these techniques for translational health research.Offered as modular courses covering the use of the following technologies and their application to basic andtranslational research: cytometry, microscopy and cell biology, genomics, proteomics, bioinformatics, and animalmodels in biomedical research.Training objectives: To be aware of the possibilities of using certain advanced techniques used in biology to study humandiseases;Apply different molecular biology techniques in laboratory research experiments;Refine the ability to approach an issue through the scientific method.ircm.qc.ca/mcm6

Option de maîtrise en médecine cellulaire et moléculaire IRCMBIM 6074 – Translational medicine practiceGraduate Cycles 2 credits Summer termCOURSE OFFERED EXCLUSIVELY TO STUDENTS OF THE MASTER'S DEGREE OPTION IN MCMLinks between the fundamental laboratory and the clinical environment; integration of solid translationalmedicine concepts and ethical issues. Exposure to the clinical environment and concepts of personalizedmedicine.Training objectives: Understand the biological basis of human diseases, their treatments and their consequences on thepatient;Summarize current challenges in medical practice and identify gaps that require investigation infundamental research;Compare these questions with the ethical considerations necessary for the conduct of researchinvolving human subjects;Integrate the fundamental knowledge of molecular biology into a concrete clinical issue.BIM 6075A – Internship with report 1Graduate Cycles 16 credits Fall termCOURSE OFFERED EXCLUSIVELY TO STUDENTS OF THE MASTER'S DEGREE OPTION IN MCMResearch project in applied human biology under supervision, with writing an internship report in the form of ascientific manuscript.Training objectives: Design and carry out molecular and cell biology experiments;Refine your logic, methods and research practice in a translational medicine context.BIM 6075B – Internship with report 2Graduate Cycles 16 credits Fall termCOURSE OFFERED EXCLUSIVELY TO STUDENTS OF THE MASTER'S DEGREE OPTION IN MCMResearch project in applied human biology under supervision, with writing an internship report in the form of ascientific manuscript.Training objectives: ircm.qc.ca/mcmDesign and carry out molecular and cell biology experiments;Refine your logic, methods and research practice in a translational medicine context.7

Option de maîtrise en médecine cellulaire et moléculaire IRCMMMD 6005R – Ethics and Health ResearchGraduate Cycles 1 credit Winter termBiomedical developments and research ethics; major regulatory texts; the ethical and technoscientificrelationship; the ethical evaluation of a project; the scientific integrity of the researcher.ircm.qc.ca/mcm8

Cursus et aperçu des cours de l’option demaîtrise MCML’option de maîtrise en médecine cellulaire et moléculaire (MCM) comprend plusieurs cours offerts dans le cadre des programmes d’étudessupérieures de biologie moléculaire de l’Université de Montréal.L’option a un cursus de cours particulier, incluant 45 crédits distribués sur une période d’une année (trois trimestres) : cinq coursobligatoires (12 crédits), deux stages en laboratoire avec rédaction de rapport (16 crédits chacun) et un séminaire de recherche (1 crédit).Ph. D.M. Sc.AutomneHiverPratique en recherchetranslationnelleBIM 6073 – 5 crStage avec rapport 1BIM 6075A – 16 crBio moléculaire et cellulaire 1BIM 6026 – 2 crObligatoire12 créditsStage32 créditsSéminaire1 créditAutomneStage avec rapport 2BIM 6075B – 16 crBio moléculaire et cellulaire 2BIM 6028 – 2 crPratique en médecinetranslationnelleBIM 6074 – 2 crÉthique et recherche en santéMMD 6005R – 1 crSéminaire de recherche 1.2BIM 6035 – 1 crSéminaire de recherche 1.1BIM 6035Légende :ÉtéPassageaccéléréau doctorat

BIM6073 : Pratique en recherchetranslationnelleR e s p o n s a b l e s : W o o ng -K y un g Suh, Nicole Francis et c o l labo r ateu rsPuisque les futurs biologistes sont dorénavant appelés à maîtriser les récentes technologies de pointe et à transposer leurs connaissancesau bénéfice du milieu clinique, la maîtrise MCM inclut une formation pratique et théorique intensive sur l’utilisation des technologies depointe en biologie moléculaire. Le cours Pratique en recherche translationnelle est offert sous le format de cours modulaires traitant del’utilisation des technologies suivantes et de leur utilisation appliquée à la recherche fondamentale et translationnelle :Cytométrie : Présentation des aspects techniques et théoriques de la cytométrie de flux et du tri cellulaire, ainsi que leurs applicationsen sciences biomédicales;Microscopie et biologie cellulaire : Utilisation de l’histologie et de l’immuno-histochimie en recherche fondamentale et dans l’analysedes échantillons cliniques. Acquisition d’images et de vidéos par diverses techniques de microscopie;Génomique : Présentation et pratique de diverses techniques pour l’étude de l’expression des gènes (microarray d’ADN; qPCR;séquençage à haut débit); Protéomique : Introduction à la protéomique et à ses stratégies pour différentes analyses (interactions protéine-protéine,phosphoprotéines, métabolites, lipides, etc.), présentation des aspects techniques de la spectrométrie de masse et l’analyse desdonnées MS;Bio-informatique : Familiarisation avec les concepts, méthodes et outils de bases de la bio-informatique, analyse de donnéesd’expériences de séquençage à grande échelle (RNA-seq et ChIP-seq);Modèles animaux en recherche biomédicale : Présentation des concepts de transgénèse, criblage génétique et édition du génome. De façon spécifique, ce cours vise les objectifs suivants : Connaître les possibilités d’utilisation de certaines techniques de pointe utilisées en biologie dans l’étude des maladies humaines;Appliquer différentes techniques de biologie moléculaire lors d’expériences de recherche en laboratoire;Affiner la capacité à aborder une question par la méthode scientifique.Cursus et aperçu des cours de l’option de maîtrise MCM

BIM6074 : Pratique en médecinetranslationnelleR e s p o n s a b l e s : André Veillette et co llabo rateursDans le cadre du cours Pratique en médecine translationnelle, les étudiants auront la possibilité de rencontrer des patients sous la supervisionde chercheurs-cliniciens. Parallèlement à l’exposition en milieu clinique, ce cours fait état des défis actuels rencontrés en clinique afin demettre l’accent sur les domaines de recherche fondamentale prioritaires qui auront un impact clinique. Les concepts de médecinepersonnalisée et les enjeux éthiques de la recherche clinique sont aussi des sujets abordés dans ce cours.De façon spécifique, ce cours vise les objectifs suivants : Comprendre les bases biologiques des maladies humaines, de leurs traitements et de leurs conséquences sur le patient;Résumer les défis actuels de la pratique médicale et mettre en évidence les lacunes nécessitant une investigation en recherchefondamentale;Mettre en parallèle ces questions avec les considérations éthiques nécessaires à la poursuite de recherche chez des sujetshumains;Intégrer les connaissances fondamentales de la biologie moléculaire à un enjeu clinique concret.Cursus et aperçu des cours de l’option de maîtrise MCM

BIM6075A et B : Stage avec rapport 1 et 2R e s p o n s a b l e s : Javier Di Noia et c o l la bo rate ur sLes étudiants à la maîtrise MCM effectuent deux stages de recherche de quatre mois, qui alternent aux trimestres d’hiver et d’été, dans deuxlaboratoires différents de leur choix en biologie moléculaire. Ainsi, dans le cadre du cours Stage avec rapport 1 et 2, les étudiants réalisent unprojet de recherche en biologie humaine appliquée sous supervision, avec rédaction d’un rapport de stage sous forme d'un manuscritscientifique.Les objectifs principaux du stage sont d’amener l’étudiant à : Concevoir et exécuter des expériences de biologie moléculaire et cellulaire;Affiner sa logique, ses méthodes et sa pratique de la recherche dans un contexte de médecine translationnelle.Cursus et aperçu des cours de l’option de maîtrise MCM

Les cours BIM6073 et BIM6074 ainsi que les stages BIM6075A et B ont été développés par le corps professoral de l’IRCM et sont offertsexclusivement aux étudiants à la maîtrise MCM.Les cours BIM6026, BIM6028 et BIM6035 sont offerts par les programmes de biologie moléculaire de l’Université de Montréal. Visitez leursite Web pour obtenir leurs descriptions.Cursus et aperçu des cours de l’option de maîtrise MCM

The PhD in Molecular Biology, option in Cellular and Molecular Medicine, is a continuation of the training of the Master's option in MCM. Offered at the IRCM, it provides students with multidisciplinary training in molecular biology with an emphasis on the latest tec

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