This Booklet Belongs To - Life Sciences Switzerland
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This booklet belongs to:If lost, please return to:Life Sciences Switzerland LS2Design by Dagmar BocakovaZurich 20202
WELCOME ADDRESSDear colleagues,We are delighted to welcome you to the FEBS3 LS2 Annual Meeting2020 at the Irchel Campus of the University of Zurich.The Life Sciences Switzerland (LS2) Annual Meeting brings togetherscientists from different countries and scientific backgrounds toexplore diverse topics under the umbrella of the life sciences. For thefirst time this year, the LS2 Annual meeting is being held as a jointFEBS3 meeting together with the German Society for Biochemistryand Molecular Biology (GBM) & Austrian Association of Molecular LifeSciences and Biotechnology (ÖGMBT).The theme of this year’s meeting is “Cells, Molecules and Organisms”with plenary talks from the earliest stages of development to tissuerepair and cellular plasticity. Discover the latest, most excitingfindings in the field, from Molecular and Cellular Biosciences,Proteomics, Physiology, Pharmacology, Biophysics, Microbiology,Neuroscience, Bioinformatics, Microscopy and more, presented byaround 30 invited speakers and over 50 speakers selected fromabstracts in eleven scientific symposia and five plenary lectures.To promote young scientists, the popular "PIs of Tomorrow" session,in which selected postdocs will present their research to a jury ofprofessors, will again be held as a plenary session. This year, flashtalks of selected posters will also be presented in the plenary sessionsas well as in symposia. Join us for the poster session with over 130posters and a new poster quiz, combined with a large industryexhibition and Apéro. For the 2020 edition, five poster prizes will beawarded!For the first time this year, we will also hold a Young Scientists’Satellite Meeting the day before the Annual Meeting, with a keynotelecture and scientific symposia of selected short talks, followed by acareer symposium and Meet and Greet Apéro with the LS2 delegatesand Annual Meeting speakers. A Public Science Policy Panel on“Vaccination in Disease Prevention” will cap the day. Invitedinternational experts will introduce this timely topic with shortlectures on different aspects of vaccination, followed by an opendiscussion with the public.3
As every year, we are also very much looking forward to the laureatetalks of the winners of the Friedrich-Miescher-Award and the LelioOrci Award.We are extremely grateful to all of our sponsors and exhibitors of the2020 edition (see page 6-7), who contributed to make this big eventpossible. Please visit their booths to learn about the latest tools andproducts, with a chance to win prizes in the Exhibition lottery.We look forward to an exciting and stimulating scientific meeting,which provides the opportunity to expand your network of colleaguesand friends and foster new collaborations, and wish you all anenjoyable and successful time.SincerelyFiona DoetschBiozentrum, University of BaselChair of the FEBS3 LS2 Annual Meeting 20204
CONTENT3568101417182227283648788283WELCOME ADDRESSCONTENTTHANKS TO OUR SPONSORS AND EXHIBITORSORGANIZING COMMITTEEFLOOR PLAN / LIST OF EXHIBITORSYOUNG SCIENTISTS’ SATELLITE MEETING PROGRAMSATELLITE MEETING: PUBLIC PANEL ONVACCINOLOGYPROGRAM OVERVIEWEXHIBITION LOTTERYPOSTER QUIZDETAILED PROGRAM DAY ONEDETAILED PROGRAM DAY TWOPOSTERSSPACE FOR NOTESUPCOMING LS2 EVENTSLS2 ANNUAL MEETING 2021 IN GENEVAACCREDITATION FOR CONTINUOUS EDUCATIONA request has been submitted to accredit the entire LS2 Annual Meeting2020 for days of continuous education in the field of animalexperimentation. Participants will be informed about the outcome by email after the meeting.CONFERENCE WIFI ACCESSAccess http://t.uzh.ch/coa& enter the Event-ID: 20ls23245NURSING & PARENTING ROOMIf you require a calm room to nurse your child, please inquire at theregistration desk for the key and directions.5
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ORGANIZING COMMITTEE 2020LS2 ANNUAL MEETING CHAIRFiona Doetsch / Biozentrum, University of BaselSCIENTIFIC COMMITTEERichard Benton / University of LausanneMarie-Noëlle Giraud / University of FribourgSusan Mango / Biozentrum, University of BaselHoward Riezman / University of GenevaSophie Martin / University of LausanneLukas Sommer / University of ZurichMarko Kaksonen / University of GenevaVolker Thiel / University of BernFEBS3 CO-ORGANIZING SOCIETIESGerman Society for Biochemistry and Molecular Biology (GBM)Blanche Schwappach / University Medical Center Göttingen, DE & GBM ChairAnke Lischeid / GBM Managing DirectorAustrian Association of Molecular Life Sciences andBiotechnology (ÖGMBT)Lukas A. Huber / Innsbruck Medical University, AT & ÖGMBT ChairAlexandra Khassidov / ÖGMBT Managing DirectorLS2 MANAGEMENT OFFICEUrs Greber / University of Zurich, President of LS2Didier Picard / University of Geneva, President-elect of LS2Jean Gruenberg / University of Geneva, Former president of LS2Carolin von Schoultz / University of Zurich, Scientific Officer LS2Elena Cardenal-Muñoz / University of Geneva, Scientific Officer LS2Jacqueline Oberholzer / University of Zurich, Executive Secretary LS2LS2 FREELANCE SUPPORT:Dagmar Bocakova / DesignDominique Ritter / Administration & accounting supportMichael Vögeli / IT infrastructureAyala Sela / Social Media8
LS2 SECTIONSMolecular and Cellular Biosciences (MCB) / Physiology / Proteomics /Autophagy / Systems Biology / Biophysics / Intersection Cardiovascular Biology/ Intersection Microscopy / Intersection BioinformaticsLS2 PARTNER SOCIETIESSwiss Chemical Society (SCS), division of Medicinal Chemistry & ChemicalBiology (DMCCB)Swiss Society for Anatomy, Histology and Embryology (SSAHE)Swiss Society for Experimental Pharmacology (SSEP)Swiss Laboratory Animal Science Association (SGV)LS2 IS A MEMBER OF THE SWISS ACADEMY OF SCIENCESLS2 EUROPEAN AND INTERNATIONAL AFFILIATIONSThe discount code for 50% offmember dues is ASCBNEW9
FLOOR PLAN LECTURES AND EXHIBITION10
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FLOOR PLAN POSTER GALLERY12
FLOOR PLAN POSTER GALLERY13
YOUNG SCIENTISTS’ SATELLITE MEETING PROGRAMWEDNESDAY 12.02.2020, 12:30 – 17:3012:30 – 13:00REGISTRATION, WELCOME COFFEE, MOUNTING OFPOSTERS13:00 – 13:05Lecture hall G95WELCOME ADDRESSFiona Doetsch (Chairof the FEBS3 LS2 Annual Meeting 2020,Biozentrum, University of Basel)Urs Greber (President of LS2, University of Zurich)13:05 – 13:40Lecture hall G9513:40 – 14:30Lecture hall G95KEYNOTE LECTUREPaola Picotti (ETH Zurich)“Proteomes in 3D”Chair: Nabil Hanna (University of Geneva)Scientific Symposium IChair: Nabil Hanna (University of Geneva)Michael Bachmann Poster #51, (University of Geneva, CH)“Ligand binding promiscuity of αVβ3 integrin isenlarged in response to mechanical force”Daniel Robert Weilandt Poster #130 (EPF Lausanne, CH)“Particle-based simulation reveals macromolecularcrowding effects on the Michaelis-Mentenparameters”Anming Huang Poster #63 (Medical University of Innsbruck, AT)“Phosphorylation of Drosophila CENP-A on serine 20regulates protein turn-over and centromere-specificloading”Ludovica Vanzan Poster #81 (University of Geneva, CH)“SOX2 acts as A “Super Pioneer Transcription Factor”by inducing replication-dependent DNAdemethylation at its binding sites”Pavel Barahtjan Poster #2 (Max Planck Institute of Molecular CellBiology and Genetics, Dresden, DE)“Measuring lipid trans-bilayer movement in cells andmodel membranes”14:30 – 15:00COFFEE BREAK, POSTER VIEWING14
15:00 – 15:25Lecture hall G95PRIX SCHLÄFLI (SCNAT) Award lectureChair: Pia Stieger (Platform Biology, SCNAT)Rebekka Wild (University of Grenoble, FR)“Control of eukaryotic phosphate homeostasis bySPX inositol polyphosphate sensor domains”15:25 – 16:00Scientific Symposium IIChair: Fanny Georgi (University of Zurich)Leonie Swart Poster #48 (University of Zurich, CH)“Divergent evolution of Legionella RCC1 repeateffectors defines the range of Ran GTPase cycletargets”Irma Querques Poster #5 (University of Zurich, CH)“Mechanisms and design of the Sleeping Beautytransposon for genome engineering”Timo Rey Poster #79 (EPF Lausanne, CH)“Mitochondrial RNA granules are liquid condensatespositioned by membrane dynamics”Chiara Borsari Poster #98 (University of Basel, CH)“Targeted therapy for neurological disorders: Anovel, orally available and brain-penetrant mTORinhibitor (PQR626)”Seimia Chebbi Poster #103 (University of Geneva, CH)“Therapeutic resistance in leukaemia: implication ofthe tyrosine kinase c-kit and integrin crosstalk”Iwona Olejniczak Poster #76 (University of Fribourg, CH)“Light your way up to a better mood. Can light helpus combat mood disorders?”16:00 – 16:30COFFEE BREAK, POSTER VIEWING15
16:30 – 17:30Lecture hall G95CAREER SYMPOSIUMPanel Discussion “How to find one’s career match?”Chairs: Fanny Georgi (University of Zurich)& Nabil Hanna (University of Geneva)Paola Picotti(Principal investigator at the Institute of MolecularSystems Biology, ETH, Zurich, CH)Ute Budliger(CEO Dr. Budliger GmbH Institute for HorticulturalTherapy and “Flower Your Mind” and Program Manager of the feminnocareer programme of the Zurich-Basel Plant Science Center, CH)Oliver Biehlmaier(Head of Imaging Core Facility, UNIBAS andLS2 Microscopy board, Basel, CH)Barbara Janssens(Head of DKFZ Career Service & AlumniRelations, German Cancer Research Center, Heidelberg, DE)17:30 – open endMEET & GREAT APÉRO WITH LS2 ANNUAL MEETING 2020SPEAKERS & LS2 DELEGATES16
SATELLITE MEETING:PUBLIC PANEL DISCUSSION ON VACCINOLOGYWEDNESDAY 12.02.2020, 18:45 – 21:0017
MAIN CONFERENCEPROGRAM OVERVIEW DAY ONE(detailed program on pages 28-35)THURSDAY 13.02.202008:00 – 09:00Lichthof areaREGISTRATION, WELCOME COFFEE, MOUNTING OFPOSTERS09:00 – 09:10Lecture hall G30WELCOME ADDRESSFiona Doetsch (Chair09:10 – 09:45Lecture hall G30of the FEBS3 LS2 Annual Meeting 2020,Biozentrum, University of Basel)Urs Greber (President of LS2, University of Zurich)PLENARY LECTURE IAlex Schier (Biozentrum, University of Basel)“Cellular biographies: reconstructing developmentaltrajectories and lineages”09:45 – 09:55Plenary flash talks09:55 – 10:30COFFEE BREAK, INDUSTRY EXHIBITION, POSTER VIEWING10:30 – 12:20Lecture hall G30SPECIAL PLENARY SESSIONPIs OF TOMORROW - THE FUTURE OF SWISSRESEARCH12:20 – 12:30Plenary flash talks12:40 – 14:45Room F68(downstairs)FEEDBACK SESSION PIs OF TOMORROWFor jury, chairs, and finalists onlyLunch bags will be delivered into the room12:30 – 13:45LUNCH BREAK, INDUSTRY EXHIBITION, POSTER VIEWING13:45 – 15:45PARALLEL SYMPOSIA I13:45 – 15:45Lecture hall G401 – UBIQUTIN SIGNALING & STRESS RESPONSES/ PROTEIN TRANSPORT & SORTINGby the FEBS3 co-organizing societies GBM & ÖGMBT13:45 – 15:45Lecture hall G602 - SMART MICROSCOPY: MACHINE LEARNING APPLIED TOLIFE SCIENCESby new LS2 intersections Bioinformatics &Microscopy18
13:45 – 15:45Lecture hall G953 – REPAIR STRATEGIES FOR THE HEART & THE VESSELS/ IMMUNOMETABOLIC CONTROL OF CANCER AND CHRONICDISEASESby LS2 Intersection Cardiovascular Biology& LS2 Section Physiology15:45 – 16:15COFFEE BREAK, INDUSTRY EXHIBITION, POSTER VIEWING15:45 – 16:15Room F68LS2 Molecular & Cellular Biosciences Section BoardMeeting (upon invitation only)16:15 – 16:45Lecture hall G30FRIEDRICH-MIESCHER-AWARD LECTURESGreta Guarda (IRB Bellinzona)“Mechanisms regulating cytotoxic immuneresponses” &Nicola Aceto (Department of Biomedicine, University of Basel)“Biology and vulnerabilities of circulating tumor cells”16:45 – 16:50Lecture hall G30FEBS and its Journals & FEBS 2020 congressUrs Greber (President of LS2 & FEBS Letters Editorial Board)Janko Kos (FEBS 2020 Congress chair, Ljubljana, Slovenia)16:50 – 17:00Lecture hall G30EU funding for Research and Innovation on theframe of Horizon EuropeEmmanouil Fragkoulis (Chair of the Science and SocietyCommittee, FEBS & University of Athens)17:00 – 17:35Lecture hall G30PLENARY LECTURE IIErin Schuman(Max-Planck-Institute for Brain Research, Frankfurt, DE)“Protein synthesis at neuronal synapses”17:35 – 18:55POSTER SESSION & INDUSTRY EXHIBITIONThe full Apéro with food will only start after thissession to allow an uninterrupted interactions atposters and booths! So please grab a drink and enjoy!Odd numbers: 17:35 – 18:15Even numbers: 18:15 – 18:5519:00 – 20:20GET-TOGETHER APÉRO free viewing of posters & industry exhibition20:20 – 21:05Room F68 (downstairs)LS2 Delegates Assembly (upon invitation only)19
MAIN CONFERENCEPROGRAM OVERVIEW DAY TWO(detailed program on pages 36-47)FRIDAY 14.02.202009:00 – 09:35Lecture hall G30PLENARY LECTURE III“THE EMBO KEYNOTE LECTURE”Melina Schuh(Max-Planck-Institute for Biophysical Chemistry, Göttingen, DE)“New insights into spindle assembly and causes ofaneuploidy in mammalian eggs”09:35 – 09:40A WORD FROM THE MEETING CHAIR FIONA DOETSCH09:40 – 10:10COFFEE BREAK, INDUSTRY EXHIBITION, POSTER VIEWING10:10 – 12:00PARALLEL SYMPOSIA II10:10 – 12:00Lecture hall G401 – CELL POLARIZATION & MORPHOGENESISby LS2 Section Molecular & Cellular Biosciences10:10 – 12:00Lecture hall G602 - PROTEOMICS IN FOOD, NUTRITION AND HEALTHSCIENCESby LS2 Section Proteomics10:10 – 12:00Lecture hall G953 – CELL BIOLOGY OF INFECTIONby Swiss Society for Microbiology Section “MolecularMicrobiology”12:00 – 13:00LUNCH BREAK & INDUSTRY EXHIBITION12:00 – 13:00Room F68SSEP Board MeetingUpon invitation only13:00 – 14:00POSTER SESSIONOdd poster numbers: 13:00 – 13:30Even poster numbers: 13:30 – 14:00Last chance to fill your poster quiz & exhibitionlottery sheet!Please bring them to the registration desk by 15:00!20
14:00 – 15:50PARALLEL SYMPOSIA III14:00 – 15:50Lecture hall G401 – CHROMATIN ORGANIZATION AND EPIGENETICREGULATIONby LS2 Section Molecular & Cellular Biosciences14:00 – 15:50Lecture hall G602 – NEURAL STEM CELLS DURING DEVELOPMENTAND IN ADULTHOODby Swiss Society for Neuroscience14:00 – 15:50Lecture hall G953 – BIOLOGICAL SYSTEMS ON THE MOLECULAR SCALEby the new LS2 Section Biophysics15:50 – 16:20COFFEE BREAK, INDUSTRY EXHIBITION, POSTER VIEWINGand in parallel:15:50 – 16:20Lecture hall G9516:20 – 16:50Lecture hall G3016:50 – 17:25Lecture hall G3017:25– 17:50Lecture hall G3017:50 – 18:00Lecture hall G30LS2 General AssemblyAll members are welcome & have voting rights!PLENARY LECTURE IVTHE LELIO ORCI AWARD LECTURESilvia Arber (Biozentrum, University of Basel & FMI Basel)“Circuits for movement”PLENARY LECTURE VYa-Chieh Hsu (Harvard University, US)“Nerve-stem cell interactions in the skin”AWARD CEREMONIES1. Prix Schläfli2. PIs of Tomorrow Award3. Poster Prizes4. Exhibition Lottery draw5. Poster Quiz drawCLOSING REMARKS & ACKNOWLEDGMENTSFiona Doetsch (Chair of the FEBS3 LS2 AnnualBiozentrum, University of Basel)Urs Greber (President of LS2, University of Zurich)18:00END OF THE CONFERENCE21Meeting 2020,
EXHIBITION LOTTERYAnswer the following questions at the exhibitor booths,collect stickers on your sticker sheet (inset in the meetingbooklet), and bring the sheet back to the registrationdesk before 14.2.2020, 15:00.Then, be present during the big lottery draw at theend of the meeting to win the following great prizes!Our sponsors of the three lottery prizes are:1. PRIZE: Noise-cancelling headphonesIGZ Instrumentsbooth #38Estimate how long it takes to purify DNA/RNAfrom tissue without centrifugation withQuickGene (Fujifilm - WAKO):a) 5 min; b) 10 min; c) 30 min; d) 45 min2. PRIZE: A Manor Gift CardJackson ImmunoResearchbooth #11aWhen using a Jackson ImmunoResearch Goatsecondary antibody what is the ideal block toprevent cross reactivity?3. PRIZE: A voucher for the Orell Füssli book storeVITARISbooth #2How many Giant Microbes can you find onour booth?22
All other participating exhibitors & their questions:Axon Lab booth #36How long does it take you to test 5 samples on theNanoPhotometer N120?Bachem booth #3When will Bachem AG celebrate its 50th anniversary?BioConcept booth #33-34Where are the cell culture media, buffers and supplementsproduced by BioConcept?Bio-Techne booth #27What are the core life science brands that make up Bio-Techne?BioTek booth #26What is the benefit of our BioSpa8 with our Imager/ReaderCytation 5?BMG Labtec booth #20This year, BMG LABTECH is celebrating a company anniversary.For how many years has BMG LABTECH been in the microplatereader business?BRAND booth #15Where is the STEP button located on the new BRANDHandyStep touch repetitive pipette?Bucher Biotec booth #31How many fluorescent colors can you image in parallel with theLogos Celena S digital microscope?Charles River booth #10How many generations of continues brother and sister matingare needed to create an INBRED strain? 10, 20, 30, or 40?Chemie Brunschwig booth #19Who is our new supplier specialized in electrophoresis? Findthe answer in one of the exhibited products.23
Enzo Life Sciences booth #211. Which one is not an Enzo's Technology Platform? Live cell analysis Chemicals Analysis Immunoassays Genomics Immunohistochemistry Small Molecule2. What is the name of Enzo’s distribution platform?Eurofins Genomics booth #29The thing I love most about my lab is GenScript booth #16GenScript is the company with the largest market share in theworld in Gene Synthesis. How much is it?A) 5% B) 10% C) 20% D) 30%(Source: QYResearch report 2018)Huberlab booth #28Which well-known supplier is leading in the field of M3D Nanotechnology?Hybrigenics booth #5How many VHH-Antibodies does the synthetic humanizednaive Llama VHH library contain?I&L Biosystems booth #7Transfer as many spheroids as possible into a new bioreactorvessel and set the correct rotation speed on the BioArray Matrixsystem.Labgene booth #23Which volumes can you homogenize with our new PrecellysEvolution?Life Systems Design booth #4Starlab's RPT: What does RPT stand for?LubionScience booth #24-25Spin our Wheel of Fortune, win a fantastic price and receiveyour stamp!Med Tech Trading booth #8Come with a smile and pick up a little candy/chocolate!MERC booth #22How many people are working worldwide for the entire MerckCompany?24
Microsynth booth #30aIn 1989, where have the first Microsynth oligonucleotides beenproduced?A) ETH student room B) Garage or C) ISO 13485 certified lab?Omni Life Sciences booth #35What is your preferred solution to improve and simplify yourcell culture for viable and mature iPSC, spheroids andorganoids?opnMe.com booth #14Fame or Future? Would you qualify for our BoehringerIngelheim post-doc program? Find it out at our booth!PeproTech booth #13Which is PeproTech’s best-selling protein?ROTH booth #37Our company is celebrating its 140th birthday! Get your freestep counter at our booth, do 140 steps, and get your sticker!SIB booth #11bJoin one of "Bioinformatics Resources for Life Scientists"demonstrations! (Multiple different resources will bepresented, and participants can decide which one to join).Socorex booth #18Guess how many pipette tips are in the vase?Takara Bio Europe booth #32Which medium does Takara offer for the derivation,maintenance, expansion, and differentiation of human andmouse neural stem (NS) cells?Thermo Fisher Scientific booth #12What does the term "advanced verification" mean when talkingabout antibodies?Twist Bioscience booth #6 On what material does Twist Bioscience print their DNA?25
Witec booth #17Which µVolume Spectrophotometer uses Acclaro SampleIntelligence Technology to detect contaminations in thesample?Promega booth #9What is called a tool on Promega.com helping you to choosethe right product for your cloning workflow?Biosystems & LabForce booth #30bWhat kind of tissue is on the slide of the Grundium scanner?Eppendorf booth #1What kind of lid variants of 25 ml Tubes are available atEppendorf?26
POSTER QUIZEach poster presenter who submitted a quiz question (see bluequestions in poster list starting on page 48) will find a sticker sheet athis/her poster. The presenter should give a sticker to every postervisitor who answered the question correctly. The collected stickers canthen be put onto the poster quiz sheet (inset in the meeting booklet),and brought back to the registration desk until 14.2.2020, 15:00.During the award ceremonies at the end of the conference, be presentto potentially win the following prize for collecting the most stickers!PRIZE: A STA Travel voucher for your next holiday tripkindly sponsored by:Jackson ImmunoResearchbooth #11a27
DETAILED PROGRAM DAY ONETHURSDAY 13.02.202008:00 – 09:00REGISTRATION, WELCOME COFFEE, MOUNTING OFPOSTERS09:00 – 09:10Lecture hall G30WELCOME ADDRESSFiona Doetsch (Chair of the FEBS3 LS2 Annual Meeting 2020,Biozentrum, University of Basel)Urs Greber (President of LS2, University of Zurich)09:10 – 09:45Lecture hall G30PLENARY LECTURE IAlex Schier (Biozentrum, University of Basel)“Cellular biographies: reconstructingdevelopmental trajectories and lineages”The development of systems ranging from embryos tometastases is governed by molecular differentiationtrajectories and cell division lineage relationships. Iwill describe our recent efforts to use single-cell RNAsequencing and CRISPR-Cas9 genome editing togenerate new tools to reconstruct developmentaltrajectories and lineage trees at very large scales.Using axial mesoderm and brain development asexamples, I will discuss the opportunities andchallenges for these technologies to provide newviews of development (also see McKenna et al. Science2016; Farrell et al. Science 2018; Raj et al. NatureBiotechnology 2018).09:45 – 09:55Plenary flash talksJenny Sülzle (EPFL Lausanne), Poster #12“Multi-color label-free imaging with interferometricscattering microscopy (iSCAT)”Lydie Lane(Swiss Institute of Bioinformatics Geneva), Poster #114“neXtProt tools for the identification and validationof human proteins by mass spectrometry”Saori Yoshii (ETH Zurich), Poster #88“Compartmentalization of mitochondria duringasymmetric cell division”28
9:55 – 10:30COFFEE BREAK, INDUSTRY EXHIBITION, POSTERVIEWING10:30 – 12:20Lecture hall G30SPECIAL PLENARY SESSIONPIs OF TOMORROW - THE FUTURE OF SWISSRESEARCHChairs: Elisa Araldi (ETH Zurich), Sophia Verouti(University of Bern), Nabil Hanna (University of Geneva) andShalu Jhanwar (University of Basel)This session offers an opportunity to postdocs andsenior researchers interested in pursuing anacademic career to present a talk similar in format toa professorship application interview. The finalistsbelow have been pre-selected from 60 eligibleapplicants. A knowledgeable jury panel ofprofessors will evaluate the presentations andprovide feedback in a one-on-one sessionafterward.Jury members of the 2020 edition:Michele de Palma (EPF Lausanne)Stefanie Jonas (ETH Zurich)Raffaella Santoro (University of Zurich)Guillaume Diss (FMI Basel)Marlen Knobloch (University of Lausanne)Beat Fierz (EPF Lausanne)10:30 – 10:35INTRODUCTORY WORDS BY THESESSIONCHAIRS OF THEThe finalists of the 2020 edition:10:35 – 11:00Eleonora Porcu (University of Lausanne)“A statistical approach for dissecting the causalmolecular underpinning of complex diseases”11:00 – 11:25Thomas Auer (University of Lausanne)“The making of an olfactory specialist”29
11:25 – 11:50Olga Murina (MRC Human Genetics Unit, Edinburgh, UK)“The Enemy Within: Mapping Cellular Responses toEndogenous DNA Damage”11:50 – 12:15Joachim Moser von Filseck (University of Geneva)“The ESCRT-III-mediated membrane deformationreconstituted in vitro”12:15 – 12:20CONCLUDING REMARKSAfterwardsCollection of public votes & feedback session forjury and finalists only (see below)12:20 – 12:30Plenary flash talksRoberto Gianni Barrera (University of Basel), Poster #31“Lateral Induction of Dll4 Expression Initiates nonSprouting Angiogenesis by VEGF”Nabil Hanna (University of Geneva), Poster #44“Time-resolved RNA-seq profiling of D. discoideuminfection by M. marinum reveals an integrated hostresponse to damage and stress”Andrea Picco (University of Geneva), Poster #11“Comparative cell biology of endocytosis in yeasts”12:40 – 14:45Room F68(downstairs)FEEDBACK SESSION PIs OF TOMORROWFor jury, chairs, and finalists onlyLunch bags will be delivered into the room12:30 – 13:45LUNCH BREAK, INDUSTRY EXHIBITION, POSTER VIEWING30
13:45 – 15:45PARALLEL SYMPOSIA I13:45 – 15:45Lecture hall G401 – UBIQUTIN SIGNALING & STRESS RESPONSES/ PROTEIN TRANSPORT & SORTINGby the FEBS3 co-organizing societies GBM &ÖGMBT*Ubiquitin Signalling and Stress Responses*by the German Society for Biochemistry andMolecular Biology (GBM)Chair: Blanche Schwappach (University Medical CenterGöttingen, DE)13:45 – 14:1514:15 – 14:45Invited speakersKonstanze Winklhofer (Ruhr-University Bochum, DE)“Ubiquitination and protein quality control:implications for neurodegenerative diseases”Thorsten Hoppe (University of Cologne, DE)“Impact of food perception on proteostasis &aging”*Protein Transport and Sorting*by the Austrian Association of Molecular LifeSciences and Biotechnology (ÖGMBT)Chair: Lukas A. Huber (Innsbruck Medical University, AT)14:45 – 15:15Invited speakersJean Gruenberg (University of Geneva)“Membrane tension in multivesicular endosomebiogenesis”15:15 – 15:45David Teis (Innsbruck Medical University, AT)“Selective membrane protein degradationpathways”13:45 – 15:45Lecture hall G602 - SMART MICROSCOPY: MACHINE LEARNING APPLIEDTO LIFE SCIENCESby the new LS2 intersections Bioinformatics &MicroscopyChairs: Sara Mitri (University of Lausanne & SIB Swiss Instituteof Bioinformatics)& Oliver Biehlmaier (Biozentrum, University of Basel)With kind support from Zeiss & Nikon31
13:45 – 14:10Invited speakersIlaria Testa (KTH Royal Institute of Technology, SE)“Smart RESOLFT for adaptive live cell imaging”14:10 – 14:35Henning Stahlberg (C-CINA, University of Basel)“Cryo-electron microscopy investigations ofneurodegeneration: a mechanistic model for thedevelopment and progression of Parkinson'sdisease”14:35 – 15:00Knut Drescher(Max-Planck Institute for Terrestrial Microbiology, DE)“Learning the space-time phases of bacterialmulticellular behavior”15:00 – 15:25Tobias Sing(Novartis Institutes for BioMedical Research NIBR, Basel)“A deep learning-based model of normal histology”Afterwards:Panel discussion on the use of smart microscopyand deep learning13:45 – 15:45Lecture hall G953 – REPAIR STRATEGIES FOR THE HEART & THE VESSELS/ IMMUNOMETABOLIC CONTROL OF CANCER ANDCHRONIC DISEASESby LS2 Intersection Cardiovascular Biology& LS2 Section Physiology*Repair Strategies for the Heart and the Vessels*by LS2 Intersection Cardiovascular BiologyChairs: Marie-Noëlle Giraud (University of Fribourg)& Andrea Banfi (University Hospital Basel)13:45 – 14:1514:15 – 14:25Invited speakerSeppo Ylä-Herttuala (University of Eastern Finland, FI)“Vascular endothelial growth factors to repairheart”Speakers from abstractsInes Marques (University of Bern), poster #28“Disruption of extracellular matrix stiffness duringscar formation hinders zebrafish heart regeneration”32
14:25 – 14:35Andrea Uccelli (University Hospital Basel), poster #32“Beyond pericytes - PDGF-BB accelerates vascularstabilization by stimulating theSemaphorin3A/Neuropilin1 monocyte axis”14:35 – 14:45Poster flash talksAlexander Akhmedov (University of Zurich), poster #25“TNFα induces Endothelial Dysfunction inExperimental and Clinical Rheumatoid Arthritis viaoxLDL Uptake by LOX-1 and Arginase 2 Activation”Loïc Dumas (University of Fribourg), poster #26“Effect of fitness prior to a myocardial infarctionevent”Grigorios Panteloglou (University of Zurich), poster #29“The coatomer (COP I) complex limits the cellsurface abundance of the LDL receptor and cellularLDL uptake”*Immunometabolic Control of Cancer and ChronicDiseases*by LS2 Section PhysiologyChair: Xiu-Fen Ming (University of Fribourg)14:45 – 15:1515:15 – 15:2515:25 – 15:35Invited speakerPing-Chih Ho (University of Lausanne)“What intratumoral Tregs eat makes them strongand vulnerable: a new metabolicintervention forcancer immunotherapy”Speakers from abstractsDobrochna Dolicka (University of Geneva), poster #17“Tristetraprolin promotes hepatic inflammation andtumour initiation but restrains cancer progression tomalignancy”Andrii Kuklin (ETH Zurich), poster #66“Cross-talk of the cytoprotective transcriptionfactors Nrf2 and NF-kB in hepatocytes suppressesspontaneous liver inflammation and fibrosis”33
15:35 – 15:40Poster flash talksTatjana Kleele (EPF Lausanne), poster #64“Distinct molecular signatures of fission predictmitochondrial degradation or proliferation”Judith Wenzina (Medical University Vienna, AT), poster #86“Inhibition of p38/MK2 signaling prevents vascularinvasion of melanoma”15:45 – 16:15COFFEE BREAK, INDUSTRY EXHIBITION, POSTERVIEWING15:45 – 16:15Room F68(downstairs)LS2 Molecular & Cellular Biosciences Section BoardMeeting (upon invitation only)16:15 – 16:45Lecture hall G3016:45 – 16:50Lecture hall G3016:50 – 17:00Lecture hall G3016:50 – 17:25Lecture hall G30FRIEDRICH-MIESCHER-AWARD LECTURESChair: Daniel Legler ((Biotechnology Institute Thurgau - BITg)Greta Guarda (IRB Bellinzona)“Mechanisms regulating cytotoxic immuneresponses” &Nicola Aceto (Department of Biomedicine, University of Basel)“Biology and vulnerabilities of circulating tumorcells”FEBS and its Journals & FEBS 2020 congressannouncement FEBS logoUrs Greber (President of LS2 & FEBS Letters Editorial Board)Janko Kos (FEBS 2020 Congress chair, Ljubljana, Slovenia)Emmanouil Fragkoulis (Chair of the Science and SocietyCommittee, FEBS & University of Athens)“EU funding for Research and Innovation on theframe of Horizon Europe“PLENARY LECTURE IIErin SchumanMax-Planck-Institute for Brain Research, Frankfurt, DE“Protein synthesis at neuronal synapses”The complex morphology of neurons, with synapseslocated 100’s of microns from the cell body,necessitates the localization of important cellbiological machines and processes within dendrites34
and axons. Using expansion microscopy together withmetabolic labeling we have discovered that bothpostsynaptic spines and presynaptic terminals exhibitrapid translation, which exhibits differentialsensitivity to different neurotransmitters andneuromodulators. These data suggest that selec
Swiss Chemical Society (SCS), division of Medicinal Chemistry & Chemical Biology (DMCCB) Swiss Society for Anatomy, Histology and Embryology (SSAHE) Swiss Society for Experimental Pharmacology (SSEP) Swiss Laboratory Animal Science Association (SGV) LS2 IS A MEMBER OF THE SWISS ACADEMY
2016 national curriculum tests Key stage 2 [BLANK PAGE] This page is intentionally blank. Contents Booklet 2B 3 Booklet 5B 15 Booklet 8C 31 Booklet 9C 47 Booklet 12P 63 Booklet 14P 75. Sene n Bet 2B First name Middle name Last name Date of birth Day Month Year School name 2016 national urriculum ets Key e 2 53208. ST002B June16. 3. Page . 02 of .
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