1 The SIBO/Histamine Bi-Phasic Diet - Naturopath

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THE SIBO/HISTAMINE BI-PHASIC DIET 1TheSIBO/HistamineBi-Phasic Diet Dr. Nirala Jacobi, BHSc, ND (USA) www.thesibodoctor.comHeidi Turner, MS, RDN www.foodlogic.org4–6 week dietary protocol for managing histamineintolerance and SIBOAbnormal amounts of these bacteriacause a number of problemsWHAT IS SIBO?1.Small intestine bacterialovergrowth is a conditionwhere bacteria which arenormally found lower in thelarge intestine have overgrownin the small intestine instead.They damage the microvilli — the absorptivesurface of the small intestine. This can lead tomalabsorption of nutrients. Microvilli are alsoresponsible for the digestion of small starch moleculesfrom food. When the microvilli are not working, thebacteria use these small starch molecules to causefermentation. This bacterial fermentation producesmethane and hydrogen gas. Not only is thisuncomfortable, but causes further damage to themicrovilli.Research has now shown that SIBO is a major cause ofintestinal permeability, or ‘leaky gut”, a conditionwhere partially digested food particles are absorbedthrough the lining of the small intestines where theycan cause an immune reaction. Leaky gut also causesbacterial by-products to be absorbed — a major triggerfor inflammation.Health care disclaimer: This treatment protocol is not intended asmedical advise and is best used with the guidance of a health careprofessional. Please ask your doctor if this protocol is appropriatefor your condition before starting. 2018 THE SIBO DOCTOR2.Leaky gut can also cause malabsorption of nutrientsfrom your food which can cause a wide variety ofsymptoms such as restless legs at night, fatigue,skin rashes, muscle aching as well as a host ofdigestive symptoms.3.The bacteria cause the motility of the small intestineto slow down or work improperly, causing furtherfermentation. Restoring proper motility in the smallintestines is a major focus of eliminating SIBO for goodand your practitioner is likely to prescribe a “prokinetic”supplement or medication.4.Many people who test positive for SIBO will also havea co-infection with fungal organisms, a condition knownas SIFO (small intestine fungal overgrowth) — the SIBOBi-Phasic diet helps to address this as well.Visit www.TheSIBODoctor.comfor more information

THE SIBO/HISTAMINE BI-PHASIC DIET 2WHAT IS THE SIBO/HISTAMINE BI-PHASIC DIET?This protocol has been developed for those suffering from SIBO and histamineintolerance. It is not intended for long term use, but rather as a starting point for thosewho have SIBO and food reactions. This diet protocol eliminates histamines andfermentable carbohydrates. Once symptoms are controlled, moving into the SIBOBi-Phasic Diet is recommended. Please consult with your practitioner before initiatingthis protocol.HISTAMINE INTOLERANCEHistamine is a substance that is made inside the body as wellas found in certain foods. In many cases of SIBO other foodsbesides fermentable carbohydrates can be problematic. Themost common reactions are to foods containing histamine.Histamine is a substance found in certain foods which cancause symptoms in those with severely disrupted mucosallining of the small intestines. The depletion of the histaminedigesting enzyme, diamine oxidase (DAO), yeast overgrowth,or the prevalence of histamine producing bacteria areoften to blame. As the overgrowth reduces and this liningrepairs, histamines typically become less problematic. Thisfood sensitivity is known as Histamine Intolerance, or HIT.Histamine is also made in the body and stored in cells knownas Mast cells. Reducing histamine foods can lower the “totalload” of histamine.SYMPTOMS OFHISTAMINE INTOLERANCENot everyone with SIBO has histamine intolerance. Beyondthe typical gastrointestinal symptoms, those with HIT oftenexperience symptoms that resemble allergies includingrunny nose, itchy eyes, sneezing, hives, asthma, and chroniccough, as well as other symptoms including headaches,joint pain, anxiety and insomnia. Not everyone with thesesymptoms has HIT but if you do, eliminating histaminesfrom the diet may provide you some additional relief duringtreatment.HISTAMINES IN THE DIETHistamines in food typically increase with age andfermentation. Fermented foods (vinegars, 24-hour yogurt,wine/beer/cider, sauerkraut, kombucha, kimchi), aged meats(bacon, sausage, ham, canned meats/fish, smoked salmon,bone broths) as well as tomatoes, spinach, eggplant, spicyfoods and chocolate are typically the most problematic forthose with HIT. Histamines also increase as food ages in the 2018 THE SIBO DOCTORrefrigerator, so leftovers can be an issue for some. There areother foods considered “histamine liberators” (HL) found incertain vegetables, fruits, nuts and eggs.Histamine liberators do not necessarily contain histamine butcan trigger a histamine response. Tolerance to these foods isdependent on the individual.A note about seafood: While seafood can easily buildhistamine as it ages, very fresh/frozen seafood may be welltolerated. White fish such as halibut, sole and cod, and veryfresh salmon are typically the best tolerated.HISTAMINE TOLERANCEEach person is difference in their tolerance and threshold tohistamine foods. Some find that histamine liberating foodsare not at all bothersome to them but high histamine foodsare. Others must avoid them all to keep their symptomscontrolled. Most, however, will have some tolerance tohistamine foods and simply need to stay under their ownpersonal threshold, or the point at which symptoms begin.HISTAMINE REDUCING FOODSTry to keep this limited diet as anti-inflammatory as possibleby including as many allowed plant-based foods as youcan and continue to test HL foods in as you are able. Useanti-inflammatory and mast cell-stabilizing herbs and spicessuch as black seed oil/spice, turmeric, cilantro, parsleyand watercress, and DAO-stimulating olive oil to flavorfoods. Try to eat as organically as you can afford to reducepesticides which can add to the histamine load for some.Some with severe histamine intolerance find a diet high inanimal protein can trigger their histamine response. We donot recommend avoiding animal protein as this can limit thediet even further. Just make sure you are focusing on plantbased fats, herbs, spices, vegetables, and fruits. If you areearly in treatment and plants are not well tolerated, cooking,blending or juicing them may be better tolerated.

THE SIBO/HISTAMINE BI-PHASIC DIET 3FERMENTED FOODSFermented foods such as cultured vegetables, sauerkraut,kimchi, as well as miso and yogurt are wonderful for thedigestive tract as they contain high amounts of probioticsor beneficial bacteria. But since these foods are highin histamine, they may not be tolerated and it is best toeliminate them from the diet for now. They can be introducedback in as your symptoms improve and your practitionerallows. Introduce no more than one tablespoon in any givenmeal and increase only as tolerated.GENERALLY AVOIDING ALCOHOLAlcohol is a known gut irritant and disrupter of the normalmicrobiome of the intestinal tract. It also reduces the amountof DAO you produce and, if fermented (ie. beer, cider andwine), contains high amounts of histamine. It is stronglyrecommended to avoid all alcohol while on the Bi-PhasicDiet. This is sometimes difficult in social situations. In theseinstances, clear spirits like vodka and gin are preferred overbeer and wine as they do not contain histamine, sulfites oryeast. Please limit alcohol consumption even in these cases.HISTAMINE ELIMINATIONAND REDUCTIONCombining a low fermentable diet with a diet that is low inhistamine can be challenging as the list of foods is narrow.While all foods high in histamine and histamine liberatorshave been eliminated from the diet in Phase 1, once yoursymptoms have calmed, you are encouraged to test inhistamine liberating foods in an effort to expand the varietyand balance of the diet. Histamine containing foods arenoted with an “H” and should be avoided until later in thetreatment process. Histamine liberating foods are noted witha “HL” and should be introduced and maintained in the dietto your personal threshold. A food with an “F/HL” indicatesit is both a fermentable carbohydrate and a histamineliberating food and should be avoided until you are readyto add more fermentable carbohydrates back into the diet,unless otherwise noted.HISTAMINE ELIMINATION 2018 THE SIBO DOCTORAND INTRODUCTION— THREE STEPSStep 1Phase 1 of the Bi-Phasic Diet lasts two–four weeks. Youshould avoid all fermentable carbohydrates, histamines andhistamine-liberating foods for at least two weeks beforeconsidering expanding the histamine liberators (HL) into thediet. Follow the food guide as to which foods to choose.Step 2After two weeks on phase 1, and only once symptoms havereduced, you can start testing HL foods if you wish. Use thePhase 2 “Allowed” list as a guide for foods to introduce. Addin one serving of a new HL food for three consecutive days.If you tolerate, you can keep that food in the diet and layerin another HL food in the same manner. Repeat, as tolerated.If you start experiencing symptoms, reduce to previouslytolerated histamine load. Know that you may tolerate oneHL food over another, so if you do react to one, wait for thesymptom to calm and then continue testing with another. Ifyou do not tolerate a particular food, avoid it until you arefurther into your treatment and test it again later, as you maygain tolerance as the gut heals. If introducing any of the HLfoods creates a return of symptoms, you should return to thebaseline diet and wait until Phase 2 before testing again.Step 3Your practitioner will advise you on when you are ready tofully move on to the Phase 2 diet. This will involve adding inhigher histamine and histamine liberating foods, as you areready. When determining which foods to add in first, alwaysconsider which foods you miss the most and what will makethe diet more enjoyable. In this phase, you will also be ableto expand more fermentable carbohydrates into the diet, asnoted.

THE SIBO/HISTAMINE BI-PHASIC DIET 4All listedquantitiesare permealPROTEINmust be freshPHASE 1 AVOID FERMENTABLE CARBOHYDRATES, HISTAMINEAND HISTAMINE LIBERATING FOODS (2–4 WEEKS)ALLOWEDBeef (organic, not aged), Lamb, Turkey (organicif available), Skinless chicken (organic)Wild/game meatsAVOIDHISTAMINEEggs (HL)Pork (HL)Seafood (H / HL) see “Histamines in Food” for info.Seasons/aged meats (ham, bacon, sausage,canned or smoked fish and meats) (H)FERMENTABLE CARBOHYDRATESLegumes, Meats seasoned with BLESone serve permealFRUITStwo servesper dayAvoid all dairyAlfalfa sprouts, Bamboo shoots, Bok choy,Capsicum/bell peppers (not spicy), Carrot,Chard, Chives, Cucumber, Ginger, Kale,Lettuce, Parsnip, Radicchio, Radish, Rocket,Spring onion (green part only), Sunflowersprouts, WitlofAvoid all diaryHISTAMINECapsicum (spicy/chili) (H)Eggplant (H)Olives (H)Spinach (H)Tomato (red) (H) green or yellow cherry tomatomay be OKFERMENTABLE CARBOHYDRATES/STARCHCauliflower, Corn, Garlic, Mushroom, Onion,Sweet Potato, Starch powder: arrowroot, corn,rice, tapiocaAsparagus – 2-3 spearsArtichoke hearts – 1/8 cupBeetroot – 2 slicesBroccoli – 1 cupBrussels sprouts – ½ cupCabbage – ¾ cupCabbage, savoy – ½ cup (wombok)Celery – ½ stickCelery root – ½ cupFennel bulb – ½ cupGreen beans – 12 eaLeek – ½ eaPeas (green) – ¼ cupPotato (white) – 1 med sizePumpkin – 1 cupSnow peas – 5 podsTomato (green or yellow cherry only) –5 eaZucchini – 1 cupBlueberries – ½ cupCantaloupe – ½ cupGrapes – 10 eaLime (to flavour, fresh squeezed)Lychee – 4Honeydew – ½ cupKiwi – 1 eaLychee – 5Papaya – ½ cupPassion fruit – 1 eaHISTAMINEAvocado (F/HL) – ¼ fruit can test in with HL butlimited to recommended amountBanana (H)Kiwi (HL) – 1 eaLemon (HL) (fresh squeezed, likely tolerated)Orange (HL)Raspberries (HL)Strawberries (HL)Tangerine (HL)ea each tsp teaspoon tbsp tablespoon 2018 THE SIBO DOCTOR

THE SIBO/HISTAMINE BI-PHASIC DIET 5All listedquantitiesare permealPHASE 1 AVOID FERMENTABLE CARBOHYDRATES, HISTAMINEAND HISTAMINE LIBERATING FOODS (2–4 WEEKS)ALLOWEDAVOIDFRUITS(CONT’D)two servesper dayPaw paw – ½ cupPomegranate – ½ small or ¼ cup of seedsRhubarb – 1 stalkFERMENTABLE CARBOHYDRATESApple, Apricot, Blackberries, Canned fruit infruit juice, Custard apple, Fig, Jam, Mango,Nashi, Nectarine, Peach, Pear, Persimmon,Plum, WatermelonGRAINS,STARCHES,BREADS ANDCEREALSAvoid all, but if practitioner allows, can limit to:Quinoa – ½ cupWhite rice (basmati, jasmine only) – ½ cupcookedAvoid all, but if practitioner allows, can limit to:Quinoa – ½ cupWhite rice (basmati, jasmine only) – ½ cupcookedLEGUMESlentils, beansAvoidAvoidSOUPSFreeze large batches in single servings toreduce histamine productionHomemade broths (organic only): chicken,beef, lamb, turkey, 2-hour broths onlyBone broth (H/F)Canned soups and soup bouillon (H/F)BEVERAGESTea (herbal)Water (filtered only)(All H): Alcohol, Beer, Cider, Club Soda, Coffee,Energy drinks, Fruit juices (H/F), Kombucha,Liqueurs and spirits (dark), Seltzer water, Softdrinks, Tea (black, green), WineSWEETENERSYeast overgrowth: limit /avoid all except SteviaDextrose/glucose, Organic honey (clear) — max.2 tbsp per day, Stevia (100% pure, no inulin)Artificial sweeteners (avoid completely) (HL),Cane sugar, Chocolate cocoa, Cacao (H/F),Maple syrup, Sugar alcohols (xylitol, mannitol,sorbitol)NUTS/SEEDSCoconut flour/shredded – ¼ cupCoconut milk (no thickeners) – ¼ cupCoconut cream — 2 tbspMacadamias – 20 eaAll other nuts/seeds (HL) — can introduce uponpractitioner’s approval to low FODMAP guidelinerecommendationsCONDIMENTSAll fresh and dried herbs and spices exceptthose noted in ‘Avoid’Green salsa (without onions/garlic)– 1-2 tbspHISTAMINECapsicum/peppers (spicy): chili, cayenne andtheir sauces (H)Allspice, Cardamom, Cinnamon, Cloves,Nutmeg (HL)Fermented sauces (such as fish, soy, coconutaminos, oyster, tamari) (H)Fermented foods (such as kimchi, sauerkraut,pickles) (H)Mayonnaise (H), Mustard (H), Vinegar (H),Tomato sauce/ketchup (H), Salsa (H)FERMENTABLE CARBOHYDRATES/STARCHREAD LABELS! No Asafetida, Chicoryroot, Garlic, Gums/carageenan/thickners,Maltodextrin, Starches, Sugar, Onions,FATS/OILSButter, Coconut, Flax (low lignin) Ghee,Grapeseed, Infused (garlic,lemon, onion), Olive,MCT, SunflowerPalm, Soyabean, Pumpkin, Sesame (HL), Walnutea each tsp teaspoon tbsp tablespoon 2018 THE SIBO DOCTOR

THE SIBO/HISTAMINE BI-PHASIC DIET 6PHASE 2 TEST HISTAMINE LIBERATING (HL) FOODS AND CONTINUETO AVOID/LIMIT HISTAMINES (H) AND FERMENTABLECARBOHYDRATES AS DIRECTED BY YOUR PRACTITIONERALLOWEDPROTEINmust be freshBeef (organic, not aged), Chicken (organic),Eggs (HL), Lamb, Pork (HL), Seafood (H/HL) see“Histamines in Food” for info, Turkey (organic ifavailable), Wild/game meatsDAIRYPRODUCTSButter, GheeHomemade yoghurt (plain, organic) (H) this isoften well tolerated — reintroduce upon yourpractitioner’s adviceVEGETABLESunlimitedVEGETABLESone-twoservings permealFRUITStwo servingsper dayAlfalfa sprouts, Bamboo shoots, Bok choy,Capsicum/bell peppers (not spicy), Carrot,Chard, Chives, Cucumber, Ginger, Kale,Lettuce, Parsnip, Radicchio, Radish, Rocket,Spring onion (green part only), Sunflowersprouts, WitlofAVOIDHISTAMINESeasons/aged meats (ham, bacon, sausage,canned or smoked fish and meats) (H)FERMENTABLE CARBOHYDRATESLegumes, Meats seasoned with garlic/onionAvoid all other diary not on allowed listHISTAMINECapsicum (spicy/chili) (H)Eggplant (H)Olives (H)Spinach (H)Tomato (H) green/yellow cherry tomato may be OKFERMENTABLE CARBOHYDRATES/STARCHCanned vegetables, Corn, Garlic, Mushroom,Onion, Sweet Potato, Starch powder: arrowroot,corn, rice, tapiocaAsparagus – 2-3 spearsArtichoke hearts – ¼ cupBeetroot – 2 slicesBroccoli – ½ cupBrussels sprouts – ½ cupCabbage – ½ cupCabbage, savoy – ¾ cup (wombok)Cauliflower – ½ cupCelery – 1 stickCelery root – ½ cupFennel bulb – ½ cupGreen beans – 10 eaLeek – ½ eaPeas (green) – ¼ cupPotato (white) – 1 med sizePumpkin – 1 cupSnow peas – 5 podsTomato (green or yellow cherry) – 5 eaZucchini – ¾ cupAvocado (F/HL) – ¼ cupBlueberries – ½ cupCantaloupe – ¼ cupCherries – 3 eaGrapes – 10 eaHoneydew – ¼ cupKiwi (HL) – 1 eaLemon (HL) – use to flavour, fresh squeezedLime (HL) – used to flavour, fresh squeezedHISTAMINEBanana (H)Orange (H)Tangerine (H)FERMENTABLE CARBOHYDRATESApple, Apricot, Blackberries, Canned fruit in fruitjuice, Custard apple, Fig, Jam, Mangoea each tsp teaspoon tbsp tablespoon 2018 THE SIBO DOCTOR

THE SIBO/HISTAMINE BI-PHASIC DIET 7PHASE 2 TEST HISTAMINE LIBERATING (HL) FOODS AND CONTINUETO AVOID/LIMIT HISTAMINES (H) AND FERMENTABLECARBOHYDRATES AS DIRECTED BY YOUR PRACTITIONERPHASE 2 DIETAVOID until further noticeFRUITStwo servingsper day(CONT’D)Lychee – 5 eaPassion fruit – 1 eaPaw paw – ¼ cupPineapple (HL) – ¼ cupPomegranate – ½ small or ¼ cup seedsRaspberries (HL) –½ cupRhubarb – 1 stalkStrawberries (HL) – ½ cupFERMENTABLE CARBOHYDRATESCONT’DNashi, Nectarine, Peach, Pear,Persimmon, Plum, WatermelonGRAINS,STARCHES,BREADS ANDCEREALSQuinoa – ½ cup per servingRice cakes (plain) – 2Rice noodles – ½ cup cookedWhite rice (basmati or jasmine only) – ½ cupcooked per servingAvoid all other grains, breads,cereals, cakes and biscuitsLEGUMESlentils, beansLentils (brown, chana, urad) – ½ cupLentils (green, red) – ¼ cupLima beans – ¼ cupAll other legumes and beansSOUPSorganicFreeze large batches in single servings toreduce histamine productionHomemade broths (organic only): chicken, beef,lamb, turkey, 2-hour broths onlyBone broth (H/F)Canned soups and soup bouillon (H/F)Alcohol (clear spirits) – no more than 30mlevery other day, Decaf Coffee (black),Seltzer water, Tea (herbal), Water (filtered only)(All H) Beer, Cider, Coffee (caffeinated),Energy drinks, Fruit juices (H/F),Kombucha, Liqueurs and spirits (dark),Soft drinks, Tea (black, green), WineDextrose/glucoseOrganic honey (clear) – no more than2 tbsp per dayStevia (100% pure, no inulin)Agave nectar, Artificial sweeteners (avoidcompletely (HL), Cane sugar, Chocolate,cocoa, cacao (H/F), Maple syrup, Sugaralcohols (xylitol,mannitol, sorbitol)BEVERAGESSWEETENERSAlmonds (HL) – 10 ea ORAlmond flour/meal – 2 tbsp ORAlmond milk (unsweetened, without addedthickners) – 1 cupNUTS ANDSEEDSCoconut (flour/shredded) – ¼ cup ORCoconut milk (without thickeners or gums) –¼ cup ORCoconut cream — 2-3 tbspHazelnuts (HL) – 20 eaMacadamias – 20 eaPecans (HL) – 40 eaPine nuts (HL) – 1 tbspPumpkin seeds (HL) – 2 tbspSesame seeds (HL) – 1 tbspSunflower seeds (HL) – 2 tbspWalnuts (HL) – 10 eaChia seeds, Flaxseed, Peanutsea each tsp teaspoon tbsp tablespoon 2018 THE SIBO DOCTOR

THE SIBO/HISTAMINE BI-PHASIC DIET 8PHASE 2 TEST HISTAMINE LIBERATING (HL) FOODS AND CONTINUETO AVOID/LIMIT HISTAMINES (H) AND FERMENTABLECARBOHYDRATES AS DIRECTED BY YOUR PRACTITIONERPHASE 2 DIETCONDIMENTSAll fresh and dried herbs and spices exceptthose noted in ‘Avoid’Mayonnaise (sugarless) (H) –1 tbspVinegar (apple cider, rice) –1 tspAVOID until further noticeHISTAMINECapsicum/peppers (spicy ie. chili, cayenne andtheir sauces) (H)Allspice, Cinnamon, Cloves, Nutmeg – smallamount OKFermented sauces (such as coconut aminos, fish,oyster, soy, tamari) (H)Fermented foods (such as kimchi, pickles,sauerkraut) (H)Mustard (H)Vinegars (H), All otherFERMENTABLE CARBOHYDRATES/STARCHESREAD LABELS! No Asafetida, Chicoryroot, Garlic, Gums/carageenan/thickners,Maltodextrin, Onions, Starches, SugarFATS/OILSButter, Coconut, Infused (garlic), Flax (lowlignin), Ghee, Grapeseed, MCT, Olive,Polyunsaturated vegetable, Pumpkin seed,Sesame, Sunflower, Walnut (HL)Palm, Soyabeanea each tsp teaspoon tbsp tablespoon 2018 THE SIBO DOCTOR

THE SIBO/HISTAMINE BI-PHASIC DIET 2 21 THE SIBO DOCTOR HISTAMINE INTOLERANCE Histamine is a substance that is made inside

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