The GI Digest

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theGI DigestA daily schedule of our activity at Digestive Disease Week 2019Department of Internal Medicine, Division of Gastroenterology and HepatologyRooms are in the San Diego Convention Center,unless indicated otherwise. Posters are listed byposter number, at the end of each day. The postersessions are from 12:00 to 2:00 pm in Halls C–E.8:00 am AGA Translational SymposiumThe need for isogenic intestinaltransplantation and biopsy bankingJason SpenceSATURDAY, MAY 188:00 – 9:30 amAGA Committee Sponsored Symposium24ABCAGA Committee-Sponsored Symposium32ABAGA Committee Sponsored Symposium24ABC7AGA Committee-Sponsored Symposium31AGlobal H. pylori prevalence against IBDincidenceJohn Y. Kao8:00 am ASGE Hands On24ABCTales from the front lines: Translating“best practices” into meaningful qualitymeasures Q&A: Panel discussionPanel: Megan A. Adams, Neil Gupta,Chien-Huan Chen, David A. LeimanHall HASGE Hands On Workshop BariatricTherapiesShelby A. Sullivan, Barham K. Abu Dayyeh,Nitin Kumar, Rachel L. Moore, VivekKumbhari, Eduardo Grecco, Manoel GalvaoNeto, Gontrand Lopez-Nava, Marvin Ryou,Allison R. SchulmanAGA Emmet B. Keeffe Symposium –Hepatitis A: It’s a Problem AgainModerators: Robert J. Fontana, KennethE. Sherman10:00 am AGA Clinical Symposium26ABFood as the main course for theirritable bowel syndromeWilliam D. Chey10:00 am Research Forum5Endoscopic Bariatric and MetabolicTherapy: Expanding the ToolkitModerators: Mark Andrew Gromski, AllisonR Schulman2:00 pm AGA Clinical Symposium26ABWhich quality metrics to track forcolonoscopy and EGDJohn I. Allen2:00 pm AGA Translational Symposium29CDGut microbial community function andhost response in IBDNobuhiko Kamada3:06 pm AGA Clinical Symposium26ABUse of monitored anesthesia care inthe endoscopy suiteMegan A. Adams3:06 pm AGA Clinical Symposium32ABDiscontinuity of care amonginflammatory bowel disease patients ina large integrated healthcare systemShirley Cohen-Mekelburg, Sameer D.Saini, Beth Wallace, John M. Hollingsworth,Julie Bynum, Jennifer Burns, Wyndy L.Wiitala, Peter D. Higgins, Akbar K. Waljee10:15 am ASGE Clinical SymposiumPolypectomy and anticoagulants/antiplatelets: What should I do?Michelle A. Anderson112:00 pm ASGE Hands OnHall HASGE Hands On Workshop Suturingand closuresNikhil A. Kumta, Prashant Kedia, Allison R.Schulman, Vivek Kumbhari, Nitin Kumar,Michael C. Larsen, Neil Gupta, A. Aziz Aadam,Pichamol Jirapinyo, Austin L. Chiang2:00 – 3:30 pm Topic Forum10:00 – 11:30 am AGA Clinical Symposium 3Prevalence and predictors of GERD andPPI-resistant GERD in the United States:results from a population-based surveyof over 71,000 AmericansSean Delshad, Christopher V. Almario,William D. Chey, Brennan Spiegel8:00 am32ABClinical features and management ofcheckpoint hepatitisRobert J. Fontana9:12 amHow are quality measures developedby AGA?Megan A. Adams8:00 am Research Forum31AAGA Committee-Sponsored Symposium8:50 am DDW Clinical SymposiumGI and Liver Complications ofImmunotherapiesModerators: Michael Dougan, Robert J.Fontana8:00 am8:22 am11:45 am – 12:30 pm Poster Tour Halls C-EGERD and Barrett’s EsophagusModerators: Joan W. Chen, Karthik RaviIBD and gut microbiomeNobuhiko KamadaTales from the front lines: Translating“best practices” into meaningfulquality measuresModerators: Megan A. Adams, Jeffrey DMosko8:00 – 9:30 am Clinical Symposium29CD43Therapeutic biliary EUS: Ready forprime time?Ryan Law3:20 – 3:50 pm ASGE Learning Center Hall EMeet the VideoGIE Top Reviewers:Learn the Art of ReviewingNotes/Moderators: Ryan Law, Lisa Cassani3:27 pm20ABCDAGA Postgraduate Course General SessionSmall intestine bacterial overgrowth:Fact and fictionWilliam D. CheySpring 2019 The GI Digest 19

5:14 pm Topic ForumSATURDAY, MAY 18 (cont’d)3:45 pm20ABCDAGA Postgraduate Course General SessionPanel Q & APanel: David A. Katzka, Linda Anh B. Nguyen,Michael Camilleri, William D. Chey4:00 – 5:30 pmASGE Clinical Symposium6ABColorectal Cancer: New Technologies,New GuidelinesModerators: John M. Carethers, Linda C.Cummings4:00 – 5:30 pmAGA Postgraduate Course Case-based Session6CHCC: Multidisciplinary approach to careAnjana A. Pillai, Neehar D. Parikh4:41 pm Basic Science Quick Shots29ALamin mutations in familial partiallipodystrophy point to phosphorylationas a therapeutic targetEric W. Lin, Graham Brady, Raymond Kwan,Alexey Nesvizhskii, M. Bishr Omary4:59 pm Topic Forum4Electrocautery setting does not affectefficacy and safety of endoscopicresection of large colorectal polypsHeiko Pohl, Ian S. Grimm, Matthew T. Moyer,Muhammad K. Hasan, Douglas K. Pleskow, B.Joseph Elmunzer, Mouen A. Khashab, OmidSanaei, Firas al Kawas, Stuart R. Gordon,Abraham Mathew, John M. Levenick, HarryR. Aslanian, Fadi Antaki, Daniel von Renteln,Seth Crockett, Amit Rastogi, Jeffrey Gill,Ryan Law, Puja S. Elias, Maria Pellise, ToddMacKenzie, Douglas K. Rex5:00 pm Research Forum30Safety and efficacy of anti-TNF therapyin older patients with ulcerative colitis:A patient-level pooled analysis of RCTdataDavid Cheng, Kelly C. Cushing, Tianxi Cai,Ashwin Ananthakrishnan20 The GI Digest Spring 20195:20 pmAGA Committee-Sponsored Symposium3Roundtable Discussions: 1.Unconscious/implicit bias; 2: Patient toprovider biasIbironke OduyeboSa1000Beyond Starbucks: Mitigating BiasThrough AwarenessModerators: Chien-Huan Chen, MiguelMalespin, Ibironke Oduyebo4:00 pmState of the art: Gender disparity in GIpracticeGrace H. EltaPOSTER SESSIONS Saturday3AGA Committee Sponsored Symposium4A national survey of internists’perceptions of PPI risks andrecommendations for deprescribingJacob Eli Kurlander, Joel H. Rubenstein,Caroline Richardson, Sarah L. Krein,Raymond De Vries, Brian J. Zikmund-Fisher,Yu-Xiao Yang, Loren Lain, Sameer D. SainiSa1028 Poster of DistinctionCost savings from generic protonpump inhibitors in Medicare Part Dfrom 2013–2016Andrew J. Read, Jacob Eli Kurlander,Akbar K. Waljee, Sameer Dev SainiSa1082 Poster of DistinctionDevelopment and validation of amachine-learning model to predictadequate bowel preparation in asample of US veteransJacob Eli Kurlander, Sameer Dev Saini,Rachel Lipson, Stacy B. Menees, ShahnazSultan, Alex Novak Kokaly, Akbar K. WaljeeSa1111Regulation of the BMP signalinginhibitor Smad6 in gastritis andgastric cancerLifang Zhang, Maria Yawen Mao, Wei Ye,Yitian Yang, Wai K. Leung, Kent-Man Chu,Fung-Yu Huang, Andrea TodiscoSa1141Validation and comparison of toolsfor selecting individuals for screeningfor Barrett’s esophagus and earlyneoplasiaJoel H. Rubenstein, Li Jiang, AkbarK. Waljee, Valbona Metko, KimberlyNofz, Maryam Khodadost, TrivelloreRaghunathan2Sa1198Management patterns for nonacidreflux patients at a large academicmedical centerChanakyaram A. Reddy, Lydia Watts,Jason Baker, Joan W. ChenSa1236Determining appropriatereimbursement for innovativeendoscopic devices using costminimization analysis: Endoscopicsuturing to prevent stent migration forbenign esophageal stricturesEric Dinesh Shah, Amy E. Hosmer, Arpan H.Patel, Shannon Morales, Ryan LawSa1276Utility of esophagram after per-oralendoscopic myotomy (POEM)Chanakyaram A. Reddy, Anna Tavakkoli,Mustafa Abdul-Hussein, Andrew C. Chang,Joan W. Chen, Mahmoud Al-Hawary, SherylJ. Korsnes, B. Joseph Elmunzer, Ryan LawSa1499 Poster of DistinctionThe impact of alcohol tax rate onmortality from alcoholic liver diseasein the United StatesNeehar Dilip Parikh, Kexin Jiang, JessicaL. Mellinger, Elliot Benjamin TapperSa1638Non-alcoholic fatty liver diseaseamong patients with heart failure withpreserved ejection fraction: Prevalence,risk factors and disease stageMonica A. Konerman, Alexandria Miller,Jennifer McNamara, Scott Hummel,Matthew KonermanSa1664Are dyssynergic defecation and alteredrectal sensation under-recognizedcause of chronic constipation inpatients taking opioids?Jason Baker, Borko Nojkov, Richard J.Saad, Stacy B. Menees, Shanti Eswaran,Allen Lee, Kimberly N. Harer, William Chey

SATURDAY, MAY 18 (cont’d)SATURDAY, MAY 18 (cont’d)SUNDAY, MAY 19 (cont’d)Sa1707 Poster of DistinctionSa20399:15 am Research ForumUsing endoscopic fine needle biopsiesof pancreatic ductal adenocarcinomafor immunotherapy precisionmedicineEileen Carpenter, Nina Steele, VeerinSirihorachai, Samantha Kemp, LawrenceDelrosario, Timothy Frankel, HowardCrawford, Michelle A. Anderson, MarinaPasca Di MaglianoUnderstanding how differences insocioeconomic status, education, andage influence treatment choice in IBSpatientsJason Baker, Lydia Watts, William L. Hasler,Kimberly N. Harer, Stacy B. Menees,Shanti Eswaran, Allen Lee, William CheyDietary serine regulates the integrityof intestinal mucus barrier duringintestinal inflammationKohei Sugihara, Nobuhiko KamadaSa1804Incidence of obstructive complicationsafter intra-abdominal surgeries inpatients with Crohn’s disease receivingcare at 12 Veterans Affairs MedicalCentersFrank I. Scott, Nicholas Bianchina, JasonKen Hou, Jennifer Burns, Wyndy L. Wiitala,Shirley Cohen-Mekelburg, Ryan W.Stidham, Akbar K. WaljeeSUNDAY, MAY 198:00 – 9:30 am AGA Research Forum30IBD: MicrobiomeModerators: Jessica Allegretti, NobuhikoKamada6DELiver Plenary IModerators: Jorge A Bezerra, Grace L. Su29BTrends of 5-ASA medication use inpatients with Crohn’s diseaseMohamed Noureldin, Shirley CohenMekelburg, Ryan W. Stidham, Peter D.R.Higgins, Shail Mahendra Govani, AmarDeshpande, Akbar K. WaljeeDietary emulsifiers reducethermogenesis in brown adiposetissue, leading to obesity andmetabolic syndromeWeiyang Zheng, Dabo Xu, Ji-Yao Li,Xiaoyin Wu, Xiaomin Hu, Merritt Gillilland,Shi-Yi Zhou, Chung OwyangSa18798:15 am DDW Clinical SymposiumDisability in patients with ileal pouchanal anastomosisMaia Kayal, Ryan C. Ungaro, Alexa Riggs,Kanika Kamal, Manasi Agrawal, ShirleyCohen-Mekelburg, Jordan Eric Axelrad,Brad Tricomi, Adam S. Faye, Ellen Scherl,Garrett Lawlor, Dana J. Lukin, Jean FredericColombel, Marla DubinskyWhat to do after negative endoscopicevaluations in obscure GI bleeding?James M. ScheimanSa2007Aspirin/NSAID use greater than 4 yearsreduces inflammatory-associatedmicrosatellite alterations in proximalcolorectal cancer (CRC) and improvespatient overall survivalYoshiki Okita, Minoru Koi, Erika Koeppe,Elena M. Stoffel, Joseph Galanko, NikkiMcCoy, Temitope O. Keku, John M. Carethers10:00 am AGA Clinical Symposium9Artificial intelligence forgastroenterologists: A primerPeter D.R. Higgins10:44 am ASGE Clinical Symposium7Overcoming benign stricturesMichelle A. Anderson10:45 am Research Forum8:00 – 9:30 am AASLD Plenary Session8:15 am Research ForumSa1808308:30 am AGA Clinical Symposium32AB25ABCKeeping to time and keeping thepatient happyWilliam D. Chey8:54 am Research Forum28E30Using deep learning for automatedgrading of endoscopic disease severityin ulcerative colitisRyan W. Stidham, Wenshuo Liu, ShrinivasBishu, Michael D. Rice, Peter D. Higgins,Brahmajee Nallamothu, Ji Zhu, Akbar K.Waljee10:50 amAGA State-of-the-Art Lecture3A novel R-spondin 1/POMCneurocircuit in the hypothalamusis activated by insulin to regulatethermogenesis in brown adiposetissueJi-Yao Li, Xiaoyin Wu, Chung Owyang10:51 am DDW Clinical Symposium32ABEndoscopic treatment of esophagealdiverticulum: What is the bestapproach?Ryan Law11:00 am Research Forum30Avoidant/restrictive foodintake disorder among adultgastroenterology behavioral healthpatients: Demographic and clinicalcharacteristicsKimberly N. Harer, Christina H. Jagielski,Megan E. Riehl, William D. CheyComplete histologic normalization isassociated with reduced risk of relapseamong patients with ulcerative colitisin complete endoscopic remissionKelly C. Cushing, William Tan, DavidH. Alpers, Vikram Deshpande, AshwinAnanthakrishnan9:00 – 11:30 am ASGE Hands-on11:05 am AASLD Clinical SymposiumCustomized Hands on LabModerators: Neil Gupta, Ryan Law3Hall H6DENon-surgical treatment of HCC andcholangiocarcinomaNeehar Dilip ParikhSpring 2019 The GI Digest 21

4:00 pm Research ForumSUNDAY, MAY 19 (cont’d)2:00 – 3:30 pm AASLD Research Forum 11AHealth Services and Outcome ResearchModerators: Elliot Benjamin Tapper,Natalie Torok2:06 pmAGA State-of-the-Art Lecture24ABCIs sucrose the sixth FODMAP in asubset of patients with irritable bowelsyndrome with diarrhea and sucraseisomaltase deficiency?Shanti L. Eswaran, Tenghao Zheng,Mauro D’Amato, William D. Chey4:00 – 5:30 pm20BCDAGA Distinguished Abstract PlenaryImmunology, Microbiology &Inflammatory Bowel Diseases SectionDistinguished Abstract PlenaryModerators: Peter D.R. Higgins, UmaMahadevan4:00 – 5:30 pm AGA Plenary Session29CDAGA Basic Science PlenaryModerators: Linda C. Samuelson, JerroldTurner4:30 – 5:30 pm ASGE Postgraduate Course 6ABBest Practices and EmergingParadigms: Session 3Moderator: Allison R Schulman4:00 – 5:30 pm AASLD Clinical Symposium 6DEPreventing Hospitalizations forPopulations with DecompensatedCirrhosisModerators: Elliot B. Tapper, Michael Volk4:00 pm AGA Clinical Symposium20ARodger Haggitt Gastrointestinal Pathology SocietySymposiumWhy mast it be so hard? Mast celldisorders of the GI tractLeslie B. Aldrich29BAutoimmune antibodies andsymptoms of autoimmune disorder ingastroparesis patientsDhruv Chaudhary, Fahad Khan, ChristinaPinkston, Thomas Abell, Henry P. Parkman,Richard W. McCallum, Kenneth L. Koch,Braden Kuo, Irene Sarosiek, Linda Anh B.Nguyen, William J. Snape, William L. Hasler,Madhusudan Grover, Gianrico Farrugia,Pankaj J. Pasricha, James Tonascia, Frank A.Hamilton, Laura Wilson4:20 pm AASLD Clinical Symposium6DEElements of effective interventionsElliot Benjamin TapperImmunology, Microbiology & Inflammatory BowelDiseasesAnti-tumor necrosis factor therapy isnot associated with post-operativeinfection: Results from prospectivecohort of ulcerative colitis and Crohn’sdisease patients undergoing surgeryto identify risk factors for postoperative infection I (PUCCINI)Benjamin L. Cohen, Phillip Fleshner,Sunanda V. Kane, Hans H. Herfarth, NicolePalekar, Francis A. Farraye, Jonathan A.Leighton, Jeffry Katz, Russell D. Cohen, Mark E.Gerich, Raymond K. Cross, Peter D. Higgins,Andrew Tinsley, Sarah C. Glover, CoreyA. Siegel, Jaime L. Bohl, Heba Iskandar,Samantha Raymond, Ruiqi Huang, MayteSuarez-Farinas, Bruce E. Sands27ABDifferential post-translationalmodification of polymorphic MSH3and novel binding partner NEMO isassociated with its nuclear-to-cytosolshuttlingStephanie Tseng-Rogenski, Wei Zheng,Minoru Koi, Yang Zhang, John M.Carethers5:15 pm Research Forum29BCharacterization of pyloric tonic andphasic pyloric motor activity usingexpanded EndoFLIP measures beforeand after G-POEM for medicationrefractory gastroparesisWilliam L. Hasler, Jason Baker,Lydia Watts, Nicole Bowers, DeepaChandhrasekhar, Allen Lee, Ryan Law22 The GI Digest Spring 2019426ABEfficacy and safety of combined CPP-1Xsulindac vs CPP-1X or sulindac alonein patients with familial adenomatouspolyposis: Results from a double-blind,randomized phase III trialCarol A. Burke, N. Jewel Samadder, EvelienDekker, Ramona M. Lim, Francesc Balaguer,Steven Gallinger, Robert Hüneburg,Christian P. Strassburg, Patrick M. Lynch,Alfred Cohen, Samir Gupta, Elena M. StoffelPOSTER SESSIONS SundaySu12804:48 pm20BCDAGA Distinguished Abstract Plenary5:00 pm Research Forum5:17 pm AGA Clinical SymposiumEfficacies of tailored therapyversus guideline-recommendedempiric therapies for eradication ofHelicobacter pylori – a trend surveyover 20 years in Taiwan (1999-2018)Chien-Chih Tung, Chi-Tan Hu, I-Nan Kuo,Bor-Ru Lin, Hong-Long Wang, Jin-De Chen,Mu-Liang Cheng, Chia-Tung Shun, MingJium Shieh, John Y. Kao, Jyh-Chin YangSu1296Superbug or something else: Factorscontributing to failure of antibioticsusceptibility-based tailored H. pylorieradicationElena Fradkov, Bei Tan, Jyh-Chin Yang,Carol L. Young, Cullen Kathleen, MinZhang, John Y. KaoSu1370Initial experience of nitrous oxidecryoballoon ablation for eradicationof nonpolypoid sporadic and familialadenomatous polyposis (FAP)duodenal adenomasOlaya I. Brewer Gutierrez, David L. Diehl,Richard Kwon, Nirav Thosani, MohamadDbouk, Harshit S. Khara, TossapolKerdsirichairat, Marcia Irene CantoSu1446Clinical characteristics of patientswith symptoms of gastroparesis andhistory of pancreatitisThomas Abell, Goro Yamada, Henry P.Parkman, Richard W. McCallum, KennethL. Koch, Braden Kuo, Irene Sarosiek, LindaAnh Bui Nguyen, William J. Snape, WilliamL. Hasler, Madhusudan Grover, GianricoFarrugia, Pankaj J. Pasricha, JamesTonascia, Frank A. Hamilton

SUNDAY, MAY 19 (cont’d)SUNDAY, MAY 19 (cont’d)SUNDAY, MAY 19 (cont’d)Su1474Su1930Su2047Concordance of vibration controlledtransient elastography, shear waveelastography, non-invasive biomarkersand liver histology in a real worldclinical settingSydni Williams, Nikhil Patel, Anna Lok,Monica A. KonermanSafety and efficacy of olorinab,a peripherally restricted, highlyselective, cannabinoid receptor 2agonist in a phase 2a study in chronicabdominal pain associated withCrohn’s diseaseBruce Yacyshyn, Daniel C. Ginsberg, Kye Gilder,Brandon Walsh, Brett English, Stewart A.Turner, Preston Klassen, Stephen B. Hanauer,Charles F. Barish, Peter D.R. HigginsFunctional lumen imaging probe isuseful for the quantification of gastricsleeve stenosis and prediction ofresponse to endoscopic dilationJessica X. Yu, Jason Baker, Joan W. Chen,Ryan Law, Amar B. Mandalia, JoelH. Rubenstein, Lydia Watts, Shelby A.Sullivan, Allison R. SchulmanSu1496Prescription opioid use and risk ofadverse clinical outcomes amongindividuals with chronic liver diseaseMonica A. Konerman, Brooke Kenney,Amit G. Singal, Elliot Benjamin Tapper,Pratima Sharma, Shari S. Rogal, Jessica L.Mellinger, Sameer Dev Saini, BrahmajeeNallamothu, Akbar K. WaljeeSu1963Amino acid sensing is an essentialmechanism of mTORC1 activation incolorectal tumorigenesisSumeet A. Solanki, Jun-Hee Lee, YatrikMadhukar ShahSu1540Su1990Identification of nuclear laminagenetic variants associated withnonalcoholic fatty liver disease in awell-phenotyped academic medicalcenter-based cohortGraham Brady, Ayse Bilge Ozel, MatthewZawistowski, Jun Li, M. Bishr OmaryFusobacterium nucleatum infectionassociates with two types ofmicrosatellite alterations in colorectalcancers (CRC)Minoru Koi, Yoshiki Okita, YoshinagaOkugawa, Takahito Kitajima, Yuji Toiyama,Erika Koeppe, Elena M. Stoffel, John M.CarethersSu1541Lamin mutations in familial partiallipodystrophy point to phosphorylationas a therapeutic targetEric W. Lin, Graham Brady, RaymondKwan, Alexey Nesvizhskii, M. Bishr OmarySu1560Pilot trial of a mobile technologybased lifestyle intervention forindividuals with non-alcoholic fattyliver diseaseMonica A. Konerman, Angela Lyden,Jane J. Wong, Lisa M. Glass, CarolineRichardson, Elizabeth Jackson, Anna LokSu1588How cost affects treatment choicefor irritable bowel syndrome withdiarrhea: A cost-effectiveness analysisof guideline-recommended treatmentinterventions to determine appropriateorder of therapy in clinical practiceEric D. Shah, Peter R. Gibson, Jane Muir,Shanti L. Eswaran, William D. CheySu1996Altered gut microbiota induced bya dietary emulsifier degrades thecolonic mucus barrier and promotesvisceral hypersensitivityDabo Xu, Xiaoyin Wu, Merritt Gillilland,Weiyang Zheng, Xiaomin Hu, Eric Martens,Chung OwyangSu2004Disruption of circadian rhythmreduces thermogenesis in brownadipose tissue, leading to abnormalweight gain and development ofmetabolic syndrome. Mediation by gutdysbiosis and endotoxemia.Xiaomin Hu, Ji-Yao Li, Xiaoyin Wu, Shi-YiZhou, Merritt Gillilland, Xu Han, WeiyangZheng, Chung Owyang5Su2055Characterizing intestinal strictures ofCrohn’s disease with a capsule-shapedacoustic resolution photoacousticendoscopeGuan Xu, Hao Lei, Laura Johnson, KathrynA. Eaton, Shengchun Liu, Jun Ni, XuedingWang, Peter D.R. HigginsMONDAY, MAY 206:30 – 7:45 am Breakfast Connections 28CDRunning a GI motility labJoan W. Chen, Abraham Khan8:00 – 9:30 am Research Forum30Prediction of Therapeutic Outcomesin IBDModerators: Kelly C. Cushing, Jenny Sauk8:00 - 9:30 am Research Forum8Hepatotoxicity and Metabolic/GeneticDiseasesModerators: Lily Dara, Robert J. Fontana8:00 – 9:30 am31AAGA Committee-Sponsored SymposiumBest of AGA at DDW in ChineseModerators: John Y. Kao, Shutian Zhang8:00 am AGA Clinical Symposium3ALD: Epidemic in the youngElliot Benjamin Tapper8:15 am Research Forum11ADeep learning models accuratelypredict development of HCC in146,218 patients with chronichepatitis CGeorge N. Ioannou, Weijing Tang, LaurenBeste, Monica A. Konerman, Grace L. Su,Tony Van, Elliot B. Tapper, Amit G. Singal,Ji Zhu, Akbar K. WaljeeSpring 2019 The GI Digest 23

10:00 amMONDAY, MAY 20 (cont’d)8:22 am33ABCAGA Committee-Sponsored SymposiumRole of probiotics in the managementof GI disease: Highlights from the AGAguidelinePurna Kashyap, Grace L. Su8:30 am31AAGA Committee-Sponsored SymposiumBest of AGA at DDW in Chinese Bestbasic abstractsJohn Y. Kao8:45 am Research Forum24ABCThe age to stop endoscopicsurveillance of Barrett’s esophagus:A cost-effectiveness analysisAmir-Houshang Omidvari, Minyi Lee,Steffie K. Naber, William D. Hazelton,Chung Yin Kong, Ellen Richmond, JoelH. Rubenstein, Georg Luebeck, John M.Inadomi, Chin Hur, Iris Lansdorp-Vogelaar9:00 am Research ForumGastric peroral endoscopic myotomy(G-POEM) for the treatment ofrefractory gastroparesis: Results fromthe first international prospective trialKia Vosoughi, Yervant Ichkhanian, Petros C.Benias, Larry S. Miller, A. Aziz Aadam, JosephTriggs, Ryan Law, Dalton Chaves, AlbertoM. da Ponte, Peter V. Draganov, Andrey IKotzev, Maan El Halabi, Omid Sanaei, OlayaI. Brewer Gutierrez, John E. Pandolfino,Anthony N. Kalloo, Mouen A. Khashab10:53 amAGA Presidential Plenary24ABC7Tackling Complex ERCPModerators: Grace H. Elta, Joanna K. Law27ABAGA Research SymposiumDefining Gastrointestinal Inflammationat the Organellar LevelModerators: Aida Habtezion, Yatrik M. Shah10:00 – 11:30 am410:00 am Topic Forum32ABCholangiocarcinoma: Definitions andpathogenesisNataliya RazumilavaASGE Clinical Symposium10:00 – 11:30 amThe business of GI practice 101John I. Allen10:00 am DDW Clinical SymposiumOveruse of surveillance endoscopy forBarrett’s esophagus in individuals withlimited life expectancyJoel H. Rubenstein, Mohamed Noureldin,Anna Tavakkoli, Chin Hur, John M. Inadomi,Iris Lansdorp-Vogelaar, Amir-HoushangOmidvari, Elissa Ozanne, Sameer D. Saini,Akbar K. Waljee10:00 – 11:30 am33ABCAGA Committee-Sponsored Symposium29B20BCDJulius Friedenwald Medal presentation toJohn I. Allen11:15 am Research Forum30Neutrophils restrict tumor-associatedmicrobiota to dampen colon tumorgrowth and invasionDaniel Triner, Samantha Devenport, YatrikM. Shah12:15 – 1:15 pmSails PavilionInteractive Education: DDW Trainee & Early CareerLounge: Meet the Expert6DEAASLD State-of-the-Art LectureDrug-Induced Liver Injury in GI PracticeModerator: Robert J. Fontana2:00 pm ASGE Clinical SymposiumTraining in endobariatrics therapy:Who, what, where, and howAllison R. Schulman2:00 pm Research ForumEscherichia coli heat-stable toxinimpairs colonic epithelial barrierfunction via cGMP-induced oxidativestress, apoptosis, and NF-κB activationTing Zheng, Shi-Yi Zhou, Sha Huang,Jason Spence, Chung Owyang2:30 pm Topic Forum66CEndoluminal functional lumenimaging probe (EndoFLIP) predictsthe outcome of gastric per-oralendoscopic pyloromyotomy (G-POEM):A multicenter prospective studyKia Vosoughi, Yervant Ichkhanian, JérémieJacques, Olivier Ragi, A. Aziz Aadam,Joseph Triggs, Petros C. Benias, Ryan Law,Nicole Bowers, Olaya I. Brewer Gutierrez,Saowanee Ngamruengphong, VivekKumbhari, Anthony N. Kalloo, John E.Pandolfino, Mouen A. Khashab3:06 pm AGA Clinical Symposium26ABWhen to test for H. pylori antibioticresistance?John Y. Kao24ABC7Improving vaccination adherence ininflammatory bowel diseases (posterpresentation)Ted Walker, Alex Thomas, Kelly C. Cushing,Michael C. Bennett, Ricardo Badillo, GregoryS. Sayuk, C. Prakash Gyawali, DeborahRubin, Cynthia Cherfan, Parakkal Deepa,Matthew A. Ciorba, George Christophi4:00 – 5:30 pm29ADistinguished Abstract PlenaryCellular & Molecular GastroenterologySection Distinguished Abstract Plenary:Stem Cells and Differentiated Cell Plasticity inMetaplasia and RegenerationModerators: Jason Mills, Linda C.Samuelson24 The GI Digest Spring 201929BAGA Committee-Sponsored SymposiumAGA Research SymposiumMicrophysiological Systems to Modelthe Neural-Epithelial Axis in the GutModerators: Tracy Grikscheit, Jason Spence11AElevated HCC risk persists for up to 10years after hepatitis C eradication inpatients with baseline cirrhosis andelevated FIB-4 scoreGeorge N. Ioannou, Amit G. Singal, ElliotB. Tapper, Akbar K. Waljee, Richard K.Sterling, Jordan J. Feld, David E. Kaplan,Tamar H. Taddei, Lauren Beste, PamelaGreen, Kristin Berry3:30 pmPractical issues of career choice,contracting, and suture paymentmodelsJohn I. Allen2:00 – 3:00 pm2:00 pm Research Forum

4:49 pm31AAGA Distinguished Abstract PlenaryMONDAY, MAY 20 (cont’d)4:00 – 5:30 pm31ADistinguished Abstract PlenaryNeurogastroenterology & MotilityDistinguished Abstract PlenaryModerators: John Pandolfino, John Wiley4:12 pm SSAT Quick Shots28CDRisk of medical complicationsfollowing bariatric surgery is elevatedin patients with immunologic diseasesJessica Jou, Allison R. Schulman,Jonathan F. Finks, Amir A. Ghaferi, OliverAdrian Varban, Ryan W. Stidham4:15 pm ASGE Clinical Symposium6CConfronting unconscious bias andstrategies to address itJohn M. Carethers4:30 pm Topic Forum4Development and initial validationof an instrument for video-basedassessment of technical skill in ERCPBadih Joseph Elmunzer, Gretchen Guiton,Catharine M. Walsh, Jose Serrano,Amitabh Chak, Steven A. Edmundowicz,Richard Kwon, Daniel Mullady, Georgios I.Papachristou, Grace H. Elta, Todd H. Baron,Patrick Yachimski, Evan L. Fogel, JasonTaylor, Vikesh Singh, Shyam Varadarajulu,Field F. Willingham, Gregory A. Cote, Peter B.Cotton, Violette C. Simon, Rebecca Spitzer,Rajesh N. Keswani, Sachin B. Wani4:45 pm Research Forum20APatricia and Ralph Giannella Lecture: All About JAK(Inhibitors) in IBDEfficacy of upadacitinib as aninduction therapy for patientswith moderately to severely activeulcerative colitis, with or withoutprevious treatment failure of biologictherapy: Data from the dose-rangingphase 2B study U-ACHIEVERemo Panaccione, Geert R. D’Haens,William J. Sandborn, Subrata Ghosh,Stefan Schreiber, Satoshi Tanida, WenZhou, Fabio Cataldi, David Pugatch, BidanHuang, Wangang Xie, Peter D. HigginsNeurogastroenterology & MotilityGut dysbiosis contributes to visceralhypersensitivity in irritable bowelsyndrome via regulation of the levelsof resolvin D1 in the colonic mucosaGintautas Grabauskas, Xiaoyin Wu,Karissa D. Kao, Chung OwyangPOSTER SESSIONS MondayMo1074Comprehensive case-matched studyon adverse events associated withgastric per oral endoscopic myotomyYervant Ichkhanian, Kia Vosoughi,Mohamad Aghaie Meybodi, JeremieJacques, Amrita Sethi, Anish Patel, A. AzizAadam, Joseph Triggs, Petros C. Benias,Dalton Chaves, Maximilien Barret, RyanLaw, Nicole Bowers, Mathieu Pioche, PeterV. Draganov, Andrey I Kotzev, EduardoAlbeniz, Fermin Estremera, Michael Ujiki,Zachary M. Callahan, Amol Bapaye,Shivangi Dorwat, Olaya I. Brewer Gutierrez,Mouen A. KhashabMo1155Patterns of care in the management ofeosinophilic esophagitisJoy W. Chang, Samuel R. Olson, Ju YoungKim, Joel Greenson, Joan W. Chen,Georgiana Sanders, Joel H. RubensteinMo1196Long term quality of life amongpatients with neoplastic Barrett’sesophagus following endoscopictherapy compared to esophagectomyChanakyaram A. Reddy, Anna Tavakkoli,Vincent L. Chen, Sheryl J. Korsnes, AartiBedi, Philip W. Carrott, Andrew C. Chang,Kiran H. Lagisetty, Richard Kwon, B.Joseph Elmunzer, Mark B. Orringer, CyrusPiraka, Anoop Prabhu, Rishi M. Reddy,Erik Wamsteker, Joel H. RubensteinMo1451Liquid biopsy for prognosis inhepatocellular carcinoma (HCC) usingcirculating tumor cells (CTCS): Asystematic review and meta-analysisVincent L. Chen, Dabo Xu, RamdaneHarouaka, Max Wicha, Anna Lok, NeeharD. Parikh7Mo1565Confocal laser endomicroscopy inpatients with functional dyspepsia:Does “leaky gut” play a role?Borko Nojkov, Russell Dolan, Julia J. Liu,Henry D. Appelman, Thomas Wang,Matthew B. Sturm, William D. CheyMo1572 Poster of DistinctionDelayed gastric emptying by wirelessmotility capsule but not scintigraphyis associated with worse symptomseverity scoresAllen Lee, Henry P. Parkman, IreneSarosiek, Linda Anh Bui Nguyen, MichaelI. Schulman, Baha Moshiree, Richard W.McCallum, John Man-Ho Wo, Satish S.C.Rao, William L. Hasler, Braden KuoMo1591Does other end-organ damagecorrelate with risk of gastroparesis indiabetics?Henry P. Parkman, Laura Wilson, KennethL. Koch, William L. Hasler, Linda Anh BuiNguyen, Thomas Abell, William J. Snape,John O. Clarke, Braden Kuo, Richard W.McCallum, Irene Sarosiek, MadhusudanGrover, Gianrico Farrugia, James Tonascia,Frank A. Hamilton, Pankaj J. PasrichaMo1592Marijuana use in patients withsymptoms of gastroparesis:Prevalence, patient characteristics,and perceived benefitHenry P. Parkman, Emily Sharkey, Linda AnhBui Nguyen, Katherine Parker Yates, WilliamJ. Snape, John O. Clarke, William L. Hasler,Kenneth L. Koch, Richard W. McCallum,Irene Sarosiek, Thomas Abell, MadhusudanGrover, Gianrico Farrugia, Braden Kuo,James Tonascia, Frank A. Hamilton, PankajJ. PasrichaMo1604Comparison of symptom and qualityof life outcomes over 6 months insuspected gastroparesis due todiabetic vs. non-diabetic etiology:Importance of diabetic subtype andgastric emptying delaysWilliam L. Hasler, Braden Kuo, Allen Lee,Linda Anh Bui Nguyen, Baha Moshiree, HenryP. Parkman, John Man-Ho Wo, Michael I.Schulman, Richard Krause, Irene Sarosiek,Richard W. McCallum, Satish S.C. RaoSpring 2019 The GI Digest 25

MONDAY, MAY 20 (cont’d)MONDAY, MAY 20 (cont’d)TUESDAY, MAY 21Mo1718 Poster of DistinctionMo18776:30 – 7:45 am Breakfast Connections 26ABRacial and geographic disparitiesin pancreatic cancer incidence andmortality in the United StatesAnna

GERD and Barrett’s Esophagus Moderators: Joan W. Chen, Karthik Ravi 12:00 pm ASGE Hands On Hall H ASGE Hands On Workshop Suturing and closures Nikhil A. Kumta, Prashant Kedia, Allison R. Schulman, Vivek Kumbhari, Nitin Kumar, Michael C. Larsen, Neil Gupta, A. Aziz Aadam, Picham

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Le genou de Lucy. Odile Jacob. 1999. Coppens Y. Pré-textes. L’homme préhistorique en morceaux. Eds Odile Jacob. 2011. Costentin J., Delaveau P. Café, thé, chocolat, les bons effets sur le cerveau et pour le corps. Editions Odile Jacob. 2010. Crawford M., Marsh D. The driving force : food in human evolution and the future.

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