TRANSFUSION OF BLOOD COMPONENTS AND NLBCP-001 .
Government of Newfoundland and LabradorDepartment of Health and Community ServicesProvincial Blood Coordinating ProgramTRANSFUSION OF BLOODCOMPONENTS ANDADMINISTRATION OF BLOODPRODUCTSOffice of AdministrativeNLBCP-001Issuing AuthorityResponsibilityMedical Advisor to the Provincial Blood Dr. Lucinda WhitmanCoordinating ProgramManager, Provincial Blood CoordinatingProgramDaphne OsborneAuthor(s)Gail Bartlett, Glenda Tapp-Ashton, DaphneOsborneEffective DateMay 13, 2017Version5.0Review Due DateMay 13, 2019Replacing the following DocumentsPolicy for Blood Component and Blood ProductAdministration NL06-001Guidelines for Patient Monitoring During aTransfusion NL2012-034Guidelines for the Initiation and Termination ofBlood Components and Blood Products NL2012040
Transfusion of Blood Components andAdministration of Blood ProductsBackgroundThe Newfoundland and Labrador Provincial Blood Coordinating Program (PBCP) providesguiding documents for Regional Health Authorities (RHAs) to ensure safety and quality carefor the transfusion of blood components and the administration of blood products topromote best practices in transfusion medicine. See PBCP Definitions.This document will provide policy, procedural and guiding principles, and linkages for thesafe transfusion of blood components and administration of blood products. Requirementsfor patient monitoring are also included in this document.Note: Special considerations for neonatal and pediatric transfusion are provided as aseparate toolkit. See Neonatal and Pediatric Transfusion Toolkit (under construction).PolicyRHAs shall develop policies and procedures that comply with PBCP policies, to ensure thatblood components and blood products are transfused/administered safely to recipients, andfor appropriate indications.1.RHAs shall ensure ongoing training for all staff who participate in transfusion of bloodcomponents and administration of blood products.2.RHAs shall establish a formal process to assess competence in transfusion-relatedactivities including maintenance of competency assessment records by both theemployee and the RHA. Transfusionists shall be competent in:2.1. Transfusion administration;2.2. Recognition and treatment of transfusion reactions and/or transfusionassociated complications; and2.3. Implementation of appropriate interventions in the event of an adversetransfusion event.See Competencies for Transfusionists of Blood Components and/or BloodProducts (under construction).3.Transfusion of blood components and administration of blood products shall beordered by a physician or other authorized health care provider. See TransfusionOrders For Blood Components And Blood Products.4.An informed consent for transfusion or administration shall be obtained by theprescriber. See Consent for or Refusal of Administration of Blood Components and/orBlood Products.NLBCP-001Version: 5.0Page 2Effective Date: 2017-05-13
Transfusion of Blood Components andAdministration of Blood Products5.The recipient shall receive information on the blood product/blood componentincluding indications for transfusion and signs of adverse effects related totransfusion. See Information for Patients/Residents/Clients (pamphlet).6.Samples for pre-transfusion compatibility testing shall be collected within 96 hoursprior to scheduled transfusion if:6.1. The recipient has been transfused with a blood component containing redblood cells within the previous three months;6.2. The recipient has been pregnant within the previous three months; or6.3. The recipient’s history is questionable or unavailable.Following transfusion of the first unit of blood, the original blood sample may beused to crossmatch additional units within 96 hours.For recipients not transfused or pregnant in the last three (3) months the samplemay be used for a time specified by the RHA/facility/transfusion medicine program.7.Requests for blood components and/or blood products sent to the TransfusionMedicine Laboratory shall include the following:7.1. Recipient first and last names;7.2. Recipient identification number;7.3. Recipient’s location;7.4. Blood component(s) or product(s) requested;7.5. Required volume, dose, or quantity; and7.6. Special requirements, if any.If recipient identification is not available, refer to Emergency Issue of BloodComponents.8.Facilities shall develop a process to identify those blood components released priorto completion of all pre-transfusion testing and/or units for which compatibilitycannot be assured (e.g. phenotypically similar). See Emergency Issue of BloodComponents.9.Continuous and unequivocal identification of the recipient and blood component orblood product shall be established from the sample collection through to transfusion.Positive recipient identification is verified at all stages of the transfusion process.9.1. At least two client identifiers are used before providing any service orperforming any procedure.NLBCP-001Version: 5.0Page 3Effective Date: 2017-05-13
Transfusion of Blood Components andAdministration of Blood Products9.2.9.3.Prior to initiating a blood component/blood product, two health care providers(or one healthcare provider and an electronic identification system) shall, inthe presence of the recipient, positively identify the recipient using two uniqueidentifiers.The compatibility label/tag shall remain attached to the blood component orblood product until the transfusion is complete.10. A policy shall be established for patient monitoring pre, during and post transfusion.10.1. The recipient shall be observed for changes in status pre, during and postblood component/blood product transfusion/administration in order to detectsigns and/or symptoms of an adverse reaction.10.2. If signs and symptoms of a transfusion reaction are exhibited, theinfusion must be stopped immediately and established facility policy formanagement of a transfusion reaction must be followed. Identification andManagement of Adverse Transfusion Events.11. RHAs shall develop policies, processes and procedures for the operation of infusiondevices and associated equipment.11.1. Only equipment and infusion devices that are approved by Health Canadashall be used.11.2. A physician (or other authorized prescriber) order is required for use of bloodwarmer or rapid infusion device with the exception of specialty areas with anestablished policy. Blood warmers are recommended to reduce hypothermiarisks in high volume rapid transfusions or the neonate population.These devices are not required in routine transfusions.11.3. Blood warmers shall: Be validated; Display biomedical certification and date visible on unit; Have a temperature alarm system and visual temperature display; Be calibrated and maintained as part of a quality control system; and Comply with CAN/CSA-C22.2 No.60601-1 and other applicablemedical device standards.12. Blood administration sets shall be connected directly to the venous access site.12.1. All administration set connections shall be secured and directly luer-locked tothe insertion site.12.2. RHA/site shall establish policies/procedures to ensure the minimal length ofintravenous tubing required is used (i.e. use only administration set with noextensions where possible or if extension set is required use the minimallength to prevent accidental disconnection).NLBCP-001Version: 5.0Page 4Effective Date: 2017-05-13
Transfusion of Blood Components andAdministration of Blood Products12.3. Air shall not be introduced into the blood component bag or administrationset.13. Administration sets shall be changed:13.1. In accordance with manufacturer’s guidelines;13.2. If the administration set becomes occluded;13.3. Immediately prior to the transfusion of platelets;13.4. If no manufacturer’s guidelines, change the transfusion administration setand filter a minimum of every 4 hours. The transfusion set may be used for amaximum of 4 units of red blood cells as long as the 4 hour period is notexce
9.3. The compatibility label/tag shall remain attached to the blood component or blood product until the transfusion is complete. 10. A policy shall be established for patient monitoring pre, during and post transfusion. 10.1. The recipient shall be observed for changes in status pre, during and post
7.1 Guidelines for recognition and management of acute transfusion reactions 28 7.2 Investigating acute transfusion reactions 29 7.3 Haemolytic transfusion reaction 30 7.4 Bacterial contamination and septic shock 31 7.5 Transfusion associated circulatory overload 31
Tissue Donor Selection Guidelines Cord Blood Donors TDSG-CB 203 (Published 01 June 2010) Release 29 (Published 24 April 2018) page 1 of 140 United Kingdom Blood Transfusion Services (UKBTS) . Scottish National Blood Transfusion Service (SNBTS) E-mail marcturner@nhs.net .
place to ensure safe blood transfusion, the risk of complication still remains. Therefore there is a need to ensure appropriateness of transfusion. These guidelines are intended to provide a quick reference to practicing clinicians in the use of blood or blood components. Sound clinical judgement
laboratory practices (GLP), good manufacturing practices (GMP) and moving towards total quality management is vital for organization and management of Blood Transfusion Services. I would like to acknowledge the contribution made by the experts in Transfusion Medicine as membe
4.4 Emerging and re-emerging infections 43 4.5 Clinically insignificant transfusion-transmissible infections 44 5 Blood screening, quarantine and release 45 5.1 Blood screening process 45 5.2 Approaches to blood screening 45 5.3 Pooling for serological assays 47 5.4 Sequential screening 47 5.5 Blood screening and diagnostic testing 48 5.6 Emergency screening 48 5.7 Screening plasma for .
Component administration 17 Preparation for transfusion 18 Blood component collection 22 Patient, prescription and pack check 24 Blood component administration 26 Post-transfusion processes 30 Blood component administration checklist 31 Product therapy and administration 35 Immunoglo
component transfused, including: Blood Bank Register (or electronic equivalent), Observation Chart, Blood Prescription Chart, Nursing and Medical Notes. There are other national drivers that are designed to promote safety in practice with blood transfusions. The Chief Medical Officer (CMO) has published two blood transfusion Health
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