CAMERON ROBERT WOLFE - UNC Gillings School Of Global Public Health

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CAMERON ROBERT WOLFE PERSONAL DETAILS: Name: Cameron Robert Wolfe, MBBS (Hons), MPH, CPDM, A.Mus.A Office: (Ms Kelly Stanly) Facsimile: Email: 1 919-668-0789 1 919-684-8902 cameron.wolfe@duke.edu EDUCATION: M.B.B.S. (Honours); University of Melbourne, 1995 – 2000 Master of Public Health (Health Policy & Management); 2013 UNC (Chapel Hill), North Carolina Certificate in Community Preparedness & Disaster Management, CPDM, UNC (Chapel Hill), North Carolina, 2010 Associate Diploma in Pianoforte: Performance; A.Mus.A, 1994, University of Sydney Member of Infectious Diseases Society of America 2007 – present Member of American Society of Transplantation 2012- present Member of International Society for Heart and Lung Transplantation 2014 - presen Member of American Society for Blood and Marrow Transplantation 2015 – present CURRENT & PREVIOUS EMPLOYMENT: Assistant Professor of Medicine: Division of Infectious Diseases & International Health Bio-preparedness Director, Duke Preparedness and Response Center, 2009 – to current Inpatient- Transplant ID Attending Physician: caring for solid organ transplant recipients, recipients of cardiac support devices, patients with malignant haematology related infections. Outpatient- HIV and Transplant Infectious Diseases care; Outreach HIV medicine - Southern Regional AHEC, Fayetteville, NC Supervision of Fellows & Medicine residents in training programs; Faculty, T32 Interdisciplinary Program in Transplant Infectious Disease Faculty, T32 Interdisciplinary Research Training Program in AIDS; Faculty, Duke Vaccine and Treatment Evaluation Unit Medical Adjudication & Advisory panel, Duke BSL3 laboratory. Infectious Disease liaison to University Student Health & Employee Health

Adjunct Lecturer: School of Public Health, University of North Carolina, Chapel Hill 2011 – to current Lectures: Infectious Disease outbreaks; Bio-surveillance and bio-vigilance; Globalisation and impacts on Infectious Disease Infectious Diseases Fellowship, 2007-2008: Duke University Medical Center Advanced Training Registrar, 2006-2007: Monash Medical Centre Inc 6-months accredited microbiology laboratory rotations Medical Residency, Advanced Registrar, 2001- 2005: St Vincent’s Hospital, Melbourne CONSULTANT APPOINTMENTS: Organ Procurement and Transplantation Network / United Network for Organ Sharing (OPTN/UNOS) - Disease Transmission Advisory Committee; national organization to review possible cases and consider issues and federal policy related to the transmission of disease and malignancy through organ transplantation, o appointed: 2012 – 2014; o Vice Chair 2014-2016 o Chairman 2016-2019 Chair, OPTN/UNOS Failure Modes Effectiveness Analysis (FMEA) Taskforce– assessing systems improvements in sharing new donor information with transplant recipient centers. Infectious Disease Society of America, Influenza Guidelines national working group, appointed 2013 - ongoing Chairman, Independent Data Monitoring Committee (IDMC); Consultant, External scientific and protocol development; GlaxoSmithKline – IV Zanamivir for the treatment of hospitalized patients with influenza, 2010-present Infectious Disease Society of America: Standards and Practice Guidelines Committee member; appointed: 2012 – 2016. Liaison to Influenza and Lyme Disease Guidelines. UNOS Committee member and NIH Review panel: HOPE Act Work Group 2014, to implement guidelines regarding safe transplantation of HIV-infected organs in the United States in accordance with Hope Act, Public Law 113-51, 113th U.S. Congress. Committee Member, 2016 CDC Special Emphasis Panel: Emerging Infections Program, CK17-1701 Lead Principal Investigator: Duke Clinical Research Institute – Gilead; GS-US-218-0108 & 218-1502 protocols for GS-5806 treatment of respiratory syncytial virus in hematopoietic stem cell transplant recipients, awarded July 2014, terminated 2016 External Medical Consultant: GSK, Internal Safety Review Committee, Danirixin Outpatient Influenza protocol, 2015-2016 Scientific Advisory Board: Invasive Aspergillosis and Rare Molds Virtual Advisory Network, Astellas Pharma, US, Inc., 2015-2016

Medical Adjudication Panel: Cellerant – Phase II clinical trial investigating use of human myeloid progenitor cells for prevention of infection during AML induction chemotherapy; commencing 2014 - 2016. Chairman, Independent Data Monitoring Committee (IDMC); Alios Biopharma, ALS-8176510 Phase 2/2b use of oral ALS-008176 for Respiratory Syncytial Virus infection, 2015-2016 Chairman, Independent Data Monitoring Committee (IDMC); JanssenBiotech, VX787FLZ2001 and 636323872FLZ2002 Phase 2/3 protocols, treating patients with JNJ63623872 in combination with oseltamivir for active infection with influenza, 2015-2016 Independent Safety Monitor: Healthy Older Adult, Phase 2 MF59-Adjuvanted, Monovalent Inactivated Influenza A/H7N9 Virus Vaccine Trial. Division of Microbiology and Infectious Diseases (DMID), National Institute of Allergy and Infectious Diseases (NIAID); Appointed 2014 - 2016 OPTN/UNOS Policy Oversight Committee: Appointed General member, 2014 – 2016 Independent Safety Monitor: Pharmacokinetics and Pharmacodynamics of Three Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adult Subjects. Protocol: 15-0049 Division of Microbiology and Infectious Diseases (DMID), National Institute of Allergy and Infectious Diseases (NIAID); Appointed 2015-2016 ACADEMIC APPOINTMENTS and PARTICIPATION: Current Physician Lead, Duke University Health System: Ebola Response Taskforce, 2014 - 2015 Duke University Ebola Travel Exemption Oversight Committee Co-Chair, Duke Influenza Vaccine Taskforce, 2010-present Member of Hospital Infection Control Committee (HICC), 2010-present Previous Member of SERCEB (Southeast Regional Center for Excellence in Emerging Infections and Biodefence) conference organizing committee, 2009-2014. Co-Chair, North Carolina Hospital Influenza Taskforce, 2010-2012 Full board member of Duke Institutional Review Board, 2009-2013 Co-team leader for two Duke Hospital medical relief missions to Haiti, 2009 Duke University Course in Scientific Leadership and Management, 2010-11 AWARDS and SCHOLARSHIPS: Duke University Hospital Strength, Hope and Caring Award, 2015 (Ebola management team) North Carolina’s Best Doctors, Dec 2015 Duke University Blue Ribbon Teamwork award, 2014 (Influenza management team) Duke University Hospital Strength, Hope and Caring Award, 2009 (individual patient care) Duke University Hospital Fellow’s Teaching award, 2008 Australian Commonwealth John Flynn Scholarship, for work in an Aboriginal community health network, 1997 – 2000 Rural Australia Medical Undergraduate Scholarship (RAMUS); awarded 2000 Chancellor’s Scholarship (Chemical Engineering); The University of Sydney, 1994

LECTURES & PRESENTATIONS: International: Wolfe CR: Lessons Learned from 2009 H1N1, Infectious Diseases Society of America 2010 Annual Meeting, Vancouver, Canada. Speaker, Session # 109, Sat 23 rd October Wolfe CR: Interactive Cases in Transplant, Interactive Panel; ID Week 2013, San Francisco, Sat 5th, 2013 Wolfe CR, Schaenman, J: Top 10 papers in Transplant Infectious Disease, ID Week 2015, San Diego, Thurs 8th, 2015 Wolfe CR: (on behalf of B.D.Alexander) Outbreak! Infection Clusters and the Transplant Center, International Society for Heart and Lung Transplantation, 36th Annual Meeting and Scientific Sessions; April 29, 2016 Wolfe CR: Donor-derived infections – Primer on Transplantation, ASM Microbe 2016, Boston, Jun 17th, 2016 University: Wolfe CR, Permar S, Moe J: Zika, an evolving challenge, Duke Innovation Challenge, Fuqua School of Business, March 22, 2016 Wolfe CR, Woods C, Bali S, Merson, M: Domestic and International Lessions from Ebola, Global Health Law and Policy Symposium, Duke University, Durham, NC, Nov 12, 2015 Wolfe CR: Infectious Diseases Complications for Transplant Recipients; Duke University 1st Annual National Lung Transplant Symposium, August 2015 Wolfe CR: New Issues in Vaccinating Adults; Duke University Internal Medicine Feb, 2015 Wolfe CR: Vector borne illness in North Carolina, North Carolina State University, Student Health, Dec 9, 2014 Wolfe CR: Hospital and Syndromic Surveillance Systems in Disaster Preparedness; Gillings School of Public Health UNC-Chapel Hill, Community Preparedness & Disaster Management Certificate lecture series, 2012-2014 Wolfe CR: Environmental and Public Health Surveillance after major disasters; Gillings School of Public Health UNC-Chapel Hill, Community Preparedness & Disaster Management Certificate lecture series, 2013-2014 Wolfe CR, Chen L: Ebola - an African Hot Zone; an American anxiety; Duke Pediatric Grand Rounds, Oct 2014 Wolfe CR: The Globalization of Infectious Disease; Gillings School of Public Health UNCChapel Hill, SPH-HPM-664, 2013 Wolfe CR: Appropriate use of antibiotics; North Carolina State University, Student Health, Dec 10, 2013 Wolfe CR, Hollingsworth J, Cheifetz I: Pandemic Influenza: Challenges, Research & Clinical Controversies; Duke University Grand Rounds, 2011 Wolfe CR: Urologic Care for the HIV patient; Duke University Urology Forum, Feb 2013 Wolfe CR: Challenging bioethics cases in the world of rationed healthcare; Duke University Bioethics Conference, 2012, February Wolfe CR, Greenwald IR, Woods C: Global Pandemics – Local Context; Duke University Winter Forum, 2011, January 10th Wolfe CR, et al: Cases in Medical Bioethics, Duke-UNC Bioethics Symposium, 2012 National:

Wolfe CR: National Reforms in Reporting of Transplant Donor-Derived Diseases; Association of Organ Procurement Organizations Tri-Council Conference, Houston, Tx, Feb 3rd, 2016 Wolfe CR: Ebola Virus response –unique issues for an Academic Medical Center; Association for Professionals in Infection Control, NC Chapter, Annual Conference, Raleigh, Sept 2015 Wolfe CR: Hospital-based Response Opportunities to Ebola Virus in North Carolina; Ebola Response: Globally to Locally, NC Communicable Diseases Conference, Raleigh, April, 2015 Wolfe CR: Emerging Infections in Transplantation; Association of Organ Procurement Organizations Tri-Council Conference, Charleston, SC, Feb 11, 2015 Wolfe CR: Ebola – clinical and emergency preparedness updates , Halifax Regional Hospital, South Boston, Virginia; Jan 26th, 2015 Wolfe CR: Infectious Disease Assessment in the Organ Donor, and Infectious Diseases in Transplant; Invited Lectures, The NATCO (Organization for Transplant Professionals) Annual Meeting, Tempe, AZ, June 2013. Wolfe CR: Infectious Diseases in Transplantation and Infectious Disease Assessment in the potential Organ Donor; Invited Lectures, The NATCO (Organization for Transplant Professionals), Annual Meeting, Tempe, AZ, June 2014 Wolfe CR, Rupprecht C, Abrahamian F, Slate D: Rabies transmission and prevention, SABoney & Associates, online webcast, June 2013 Wolfe CR: Updates in HIV care; Infectious Diseases Society of America, NC Chapter, 2012 Annual Meeting. Charlotte, Nov 17th, 2012. Wolfe CR: Transgender health issues and Meds in HIV: New Developments; 30year later: HIV conference 2012; Southern Regional AHEC, Fayetteville, NC, Nov 2012 Wolfe CR: Viral hepatitis – updates on Risks, Rates and Ravages; Infusion Nurses Society, Annual Convention, 2011, Louisville, KN, May 23 rd Wolfe CR: HIV – toxicities, transmission and treatment; Infusion Nurses Society, Annual Convention, Nashville, TN, 2009, May 5th PUBLICATIONS: RF Chemaly, SL Aitken, CR Wolfe, R Jain, MJ Boeckh: Aerosolized Ribavirin: the most expensive drug for pneumonia; Transplant Infectious Disease, 18 (3), 2016 Green, Michael; Covington, Shandie; Taranto, Sarah; Wolfe, Cameron; Bell, Walter; Biggins, Scott W.; Conti, David; DeStefano, G. David; Dominguez, Edward; Ennis, Donna; Gross, Thomas; Klassen-Fischer, Mary; Kotton, Camille; LaPointe-Rudow, Dianne; Law, Yuk; Ludrosky, Kristen; Menegus, Marilyn; Morris, Michele I.; Nalesnik, Michael A.; Pavlakis, Martha; Pruett, Timothy; Sifri, Costi; Kaul, Daniel; Donor-Derived Transmission Events in 2013: A Report of the Organ Procurement Transplant Network Ad Hoc Disease Transmission Advisory Committee, Transplantation, 2015 Feb;99(2):282-7 Argento C, Wolfe CR, Wahidi M, Shofer S, Mahmood K; Broncho-Mediastinal Fistula Caused by Endobronchial Aspergilloma , Annals of the American Thoracic Society, 2015 Jan;12(1):91-5 Kaul D, Mehta A, Wolfe CR, Green M, Blumberg E; Ebola Virus Disease: Implications for Solid Organ Transplantation; American Journal of Transplantation, Dec 15, 2014 Catania.J, Que.L, Govert.J, Hollingsworth.J, Wolfe.CR; High ICU admission rate for 20132014 Influenza is associated with a low rate of vaccination; American Journal of Respiratory and Critical Care Medicine, Vol. 189, No.4 (2014), pp. 485-487

Chen LF, Dailey NJ, Rao AK, Fleischauer AT, Greenwald I, Deyde VM, Moore ZS, Anderson DJ, Duffy J, Gubareva LV, Sexton DJ, Fry AM, Srinivasan A, Wolfe CR., Cluster of Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Virus Infections on a Hospital Ward among Immunocompromised Patients--North Carolina, 2009. Journal of Infectious Diseases 2011 203: 838-846 Martin S, Hollingsworth C, Norfolk S, Wolfe, C and Hollingsworth J; Reversible cardiac dysfunction associated with pandemic 2009 influenza A(H1N1) Chest. 2010 May;137(5):1195-7. Chest. 2010 May;137(5):1195-7 Brown-Elliott B, Iakhiaeva E, Griffith D, Woods G, Stout J, Wolfe CR, Turenne C and Wallace R; In Vitro Activity of Amikacin Against Isolates of Mycobacterium avium complex with Proposed MIC Breakpoints And Finding of a 16S rRNA Gene Mutation in Treated Isolates, J Clin Microbiol. 2013 Oct;51(10):3389-94 Gargano L, Wolfe C, et al; Issues in the Development of a Research and Education Framework for One Health Emerg Infect Dis 2013; Vol 19, Number 3 Biggs H, Chudgar S, Pfeiffer C, Rice K, Zaas A, Wolfe CR; Disseminated Mycobacterium immunogenum infection presenting with septic shock and skin lesions in a renal transplant recipient; Transplant Infectious Disease 2012 Martin, S, Hollingsworth C, Norfolk S, Wolfe C and Hollingsworth J; Response: Pandemic H1N1 and cardiac dysfunction. Chest, 2011. Lisa M. Gargano, Patrick F. Gallagher, Ashley S. Freeman, J. Glenn Morris, Susan Temporado Cookson, Ian Greenwald, Paola Lichtenberger, Wilbur K. Milhous, Mildred Williams-Johnson, Cameron Wolfe, Alexander Isakov, Christopher W. Woods, and James M. Hughes; Academic Consortia: Untapped Resources for Preparedness, Response, and Recovery—Examining the Cholera Outbreak in Haiti. Emerg Infect Dis 2011, 17(11) Epub Oct 2011. Wolfe CR. Case Report: Treatment of Chronic Osteomyelitis; Clin Infect Dis. 2011 Jun;52 Wolfe, CR and Hicks, C; Darunavir – A clinical review, HIV/AIDS – Research and Palliative Care, 2009 (1):13-21, DOI 10.2147/HIV.S4842 Taylor SM, Wolfe CR, Dixon TC, Ruch DS, Cox GM; Wound botulism complicating the internal fixation of a complex radial fracture, J Clin Microbiol. 2010 Feb;48(2):650-3. Epub 2009 Dec 9 Norfolk SG, Hollingsworth CL, Wolfe CR, Govert JA, Que LG, Cheifetz IM, Hollingsworth JW.; Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: a tertiary center intensive care unit experience from April to October 2009; Crit Care Med. November 2010, 38(11), pp 2103-2107 Wolfe CR, Greenwald I, Chen L. Pandemic (H1N1) 20009 and oseltamivir resistance in hematology/oncology patients. Emerg Infect Dis 2010, 16(11) p1808-1811 Wolfe CR; Staying Committed in Haiti; News & Observer; May 29, 2010

POSTER PRESENTATIONS and ABSTRACTS: CR Wolfe, AR Wilk, CD Sifri, M Morris, A Mehta and D Kaul: Donor-derived Toxoplasmosis in Solid Organ Transplant 2008-2015: Opportunities for improvement; 2016 American Transplant Congress, Boston, MA, June 12, 2016 AR Wilk, S Taranto, CR Wolfe, M. Nalesnik: Recipient Outcomes in U.S. Cases of PostDonation Living Donor Malignancy; 2016 American Transplant Congress, Boston, MA, June 13, 2016 ML Volk, AR Wilk, CR Wolfe, D Kaul: “PHS Increased Risk” label is associated with nonutilizaqtion of hundreds of organs per year; 2016 American Transplant Congress, Boston, MA, June 13, 2016 D Kaul, S Tlusty, A Wilk, and C Wolfe: A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC); 2016 American Transplant Congress, Boston MA, June 12, 2016 J. Schaenman, A Wilk, S Tlusty, M Michaels, CR Wolfe, D Kaul: Donor Derived Disease Transmission Events in Thoracic Organ Transplantation: Data Reviewed by the OPTN Ad Hoc Disease Transmission Advisory Committee; International Society for Heath and Lung Transplantation Annual Meeting, Washington D.C., April, 2016. Abstract 2788 AW Baker, SS Lewis, BD Alexander, P Isaacs, LC Pickett, RJ Wallace Jr, BA Brown-Elliott, N Strittholt, KC Hazen, CR Wolfe, EK Maziarz, JHoran, RD Davis, JM Reynolds, D Anderson, DJ Sexton, LF Chen: A Cluster of Mycobacterium abscessus among Lung Transplant Patients: Investigation and Mitigation; IDWeek, Oct 8, 2015, San Diego R Bartz, J Hollingsworth, P Aguilar, K Klein, J Bohman, D Kor, H Babcock, D Schuller, B Blough, A Swink, K Bartels, M Barron, A Babu, Lisa Boorman, M Cooter, M Daneshmand, CR Wolfe, P Park: Outcomes of hospitalized influenza-positive patients at large U.S.Extracorporaeal membrane oxygenation centers during 2013-2014 influenza season; presented at American Thoracic Society 2015, Denver, May 2015 M Green, S Taranto, S Covington, M Michaels, C Wolfe, D Kaul; Pediatrics & Donor Derived Disease Transmission: The US OPTN Experience; Oral Abstract, American Transplant Congress; Philadelphia, May 6th, 2015 Epling C, Shulby G, Wolfe CR, Andolsek K; Transitioning Influenza Vaccination from a Recommendation to a “Condition of Employmnt” for over 23,000 employees; presented at: o NPSF Annual Patient Safety Congress, Austin, Tx, April 29, 2015 o International Forum on Quality and Safety in Health Care, April 24, 2015, London, o DUHS Patient Safety Conference, Durham, March 2015 ME Clement, SG Norfolk, JM Reynolds, CR Wolfe, EKMaziarz: Prostate as Sanctuary Site: Relapsed Blastomycosis in a Lung Transplant Recipient; International Society for Heart and Lung Transplantation, Accepted for presentation - Nice, 2015. Abstract ID 2015-JF-2661ISHLT Wolfe CR, Greenwald I, Thompson J; Telemedicine and its effects on disaster support team member selection; International Conference on Emergency Medicine, June 2010, Abstract ID : F-POS414/IT Wolfe CR, Greenwald I, Thompson J; Academic medical centers and the creation of international disaster support teams; International Conference on Emergency Medicine, June 2010, Abstract ID: T-POS191/DIS Chen LF, Dailey NJ, Rao AK, Fleischauer AT, Greenwald I, Deyde VM, Moore ZS, Anderson DJ, Duffy J, Gubareva LV, Sexton DJ, Fry AM, Srinivasan A, Wolfe CR; Cluster of Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Virus Among Immunocompromised Patients on a Hospital Ward — North Carolina; SHEA Decennial International Conference on Healthcare-Associated Infections; March 2010, Abstract ID: 3013 C. Wolfe, D. Turner, C. Rudd, J. Pham, I. Cheifetz; Intravenous Zanamivir for Critical Illness due to Pandemic H1N1 Influenza, SCCM, 40TH Critical Care Conference; Jan, 2011, Abstract ID: 777

D.Kaul, C.Wolfe, et al; Time to Presentation of Donor Derived Infection; 2013 American Transplant Congress, May 18, 2013; Abstract ID: B1038 CR Wolfe, C.Kotton, D.Kaul, M.Green, S.Taranto, M.Morris; Geographic variation in donorderived transplant infections; 2014 World Transplant Congress, Seattle, July, 2014 L.Porras, B.Boggess, CR Wolfe; Scarier than Acne: Chronic Shoulder Pain Caused By P. Acnes Septic Arthritis; American Medical Society for Sports Medicine, 2014 M Green, S Covington, S Taranto, W Bell, SW Biggins, E Blumberg, G DeStafano, E Dominguez, D Ennis, T Gross, M Klassen-Fischer, C Kotton, S Kusne, Y Law, M Menegus, R Miller, M Pavlakas, T L Pruett, D LaPointe-Rudow, P Ruiz, N Siparsky, M Souter, L Weiss, C Wolfe and D Kaul: Donor Derived Transmission Events in 2012: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC); 2013 American Transplant Congress, May 2013 S Kusne, S Taranto, S Convington, D Kaul C Wolfe and M Green: Transmission of Coccidioidomycosis through Organ Transplantation; oral abstract, 2013 American Transplant Congress, May, 18, 2013 M Green, S Covington, S Taranto, , C Wolfe and D Kaul: A report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC); oral abstract, 2014 World Transplant Congress, Seattle, July 2014, BOOK CHAPTERS: Wolfe CR and Visvanathan, K; Chapter - Rheumatic Fever , Infectious Diseases, Cohen, Powderly, Opal et al, 3rd Edition, 2009 Elsevier Wolfe CR; Identifying & managing casualties of biological terrorism; UpToDate, Edition 18.4, 2012. NOTABLE ACHIEVEMENTS: The London International Youth Science Forum, 1993; Australian Representative; including: o Queen’s Trust Scholarship, 1993 Australia Day Young Citizen nominee; 1994 Team Leader; International Physics Olympiad, Canberra 1995; Canada 1997 Student representative and staff member, CRA National Youth Science Forum; 1993 -1995 EXTRA MEDICAL ACTIVITIES: Conference Organizing Committee: 2010 SERCEB conference: Engaging Public Health, Academia and Research in Pandemic Preparedness, 2010 SERCEB conference: Role of Academic Medical Centers in international and local disaster relief, 2011 SERCEB conference: Examining the Role of Academic Consortia in Epidemic Preparedness, Response, and Recovery – Cholera in Haiti 2012 SERCEB/SECEPT conference: Developing a Research and Education Agenda for One Health, Ad hoc Manuscript Reviewer: o Blood, 2015- 2016

o o o o o o o o Clinical Infectious Diseases, 2014-2016 American Journal of Transplantation, 2012 – 2016 Journal of Heart and Lung Transplantation, 2012 – 2016 Transplant Infectious Diseases, 2014 - 2016 BMC Infectious Diseases 2014 - 2015 North Carolina Medical Journal 2014 Oxford University Press – HIV publications, 2012 - 2013 DovePress: HIV/AIDS - Research and Palliative Care, Neurobehavioral HIV Medicine, 2010 Volunteer Physician, 2002: East Timor: 13 weeks associated with Jesuit Refugee Service: Maliana District Hospital, East Timor Ethiopia: 8 weeks associated with Missionaries of Charity, Mother Theresa Sisters: Hiv/A.I.D.S. Hospice, Addis Ababa; again, Oct 2012. Rwanda: 8 weeks associated with World Vision, East Africa, Gahini District Hospital Kenya: 4 weeks associated with World Vision, East Africa, working in Kibera, Nairobi. Medical Electives,2000 – 3 months spent in: Malawi: St John’s Hospital, Mzuzu– Medicine Kenya: Kikuyu Hospital, Kikuyu– Orthopaedics, Trauma Uganda: Kisiizi Hospital, Uganda– Medicine Tutor: Pathology, Histology, Histopathology, Embryology, Queen’s College, 1999-2001, 2003 Melbourne University Rural and Remote Medicine Club (“Outlook”) Vice-President, Secretary and Chairman; Queen’s College Sports & Social Club; 1996-1998 respectively Queen’s College Council, Melbourne University, 1997 CURRENT & PREVIOUS FUNDING: NIEHS, Grant Number: 1UH4ES027072-01 Ebola Biosafety and Infectious Disease Response Training June 2016 – May 2019 Project Title: Duke Infectious Disease Response Training Consortium (DIDRT) Dr Wolfe is a co-Principal Investigator at the lead site, Duke University, working together with faculty from the Duke Human Vaccine Institute and the Regional Biocontainment Laboratory to create teaching and training modules for biosafety training specific to Ebola virus and other novel emerging pathogens NIAID, SSS CRB-DCR01-5-09-00318* 12/01/09 - 2013 Active Influenza Research Collaborative Sites Combination Therapy Working Group Dr Wolfe is a representative of Duke University Health System providing leadership regarding combination chemotherapeutic development for influenza. Merck – MISP

02/01/12 – current Active Raltegravir Use in HIV patients receiving Solid Organ Transplantation Dr Wolfe is the PI of a Duke University investigator-initiated, industry-funded study of Raltegravir as an antiretroviral drug of choice for HIV patients with organ transplantation. UNC – SERCEB, W00445725-30733 03/1/11 – 2014 Active Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Dr Wolfe is an investigator on a regional biodefense and emerging infection grant centered at University of North Carolina at Chapel Hill. ACTG Adult AIDS Clinical Trials Unit (Thielman), NIH 5U01AI069484-04 12/06 - 2015 Active To develop and implement hypothesis-driven, pathogenesis-based innovative clinical trials for persons with HIV infection. Dr Wolfe is a co-investigator. Glaxo Smith Kline – NAI 114373 10/18/10 – current Active Zanamivir for the treatment of severe influenza Dr Wolfe assists with statistics, safety and development of protocols for analysis of influenza treatment options. Research Grant – Roche 2011-2014 Active Oseltamivir dosing for influenza in immunocompromised patients Dr Wolfe is a local PI at the Duke University site. Research Grants – NIAID/Insight: FLU002, FLU003, FLU004, IRC003, FLU006-IVIG 2011- current Active Dosing and observational studies for influenza Dr Wolfe is a local PI at the Duke University site for five independently run NIH-funded influenza studies observing treatment outcomes for high-risk outpatients and inpatients. Research Grant – Ansun Biopharma 2013- current Active Use of DAS-181 for treat of Parainfluenza infection in immunocompromised patients Dr Wolfe is a local PI at the Duke University site SAMPLE MEDIA PRESENTATIONS: Mary Brophy Marcus: Vaccine arrives as flu spreads; USA Today, Oct 6, 2010 o ne-flu-vaccine N.htm

WRAL news, Oct 12, 2009 http://www.wral.com/news/local/video/6198033/ Sarah Avery: Duke concerned about drug resistant swine flu; The Charlotte Observer, Nov 21, 2009 o 2/duke-concerned-about-drugresistant.html Radio: Here’s to your health: H1N1 influenza vaccination; 1360 WCHL, Feb 10, 2010; The Herald Sun: Matthew Milliken: Duke medical team heading to Haiti; Feb 4, 2010 o http://www.heraldsun.com/view/full Haiti?instance most recommended ABC 11 news: Duke doctors head to Haiti; Feb 4, 2010-08-1 o http://abclocal.go.com/wtvd/story?section news/local&id 7257000 MedPage Today, Infectious Disease, West Nile Cost: 778 Million; Feb 10, 2014 o ralInfectiousDisease/44232 Radio WPTF-Talk Radio 850AM: http://www.wptf.com/ mp3 available upon request. o Jan 6, 2014 Compare: Josh Zach, Topic: Infectious Disease Preparedness o Jan 6, 2014 Compare: Josh Zach, Topic: Cold Temperatures and Flu Season o Jan 7, 2014 Compare: Josh Zach, Topic: Duke Medicine restricts hospital visitation o Feb 28, 2014 Compare: Brandon Dickson, Topic: Influenza mortality and spread o Jan 29, 2016 Compare: Josh Zach, Topic: Zika virus infections and pregnancy Forbes.com: David Knoll: More proof the flu vaccine works; Feb 16, 2014 o more-proof-the-flu-vaccineworks/ US News & World Report: Flu hits unvaccinated hardest study finds; Feb 14, 2014 o /02/14/flu-hits-unvaccinatedhardest-study-finds National Public Radio (NPR), Maanvi Singh: With this year’s flu young adults are not so invincible; Feb 13, 2014 o ncible New York Times, Nicholas Bakalar: Young adults need flu shots too; Feb 12, 2014 o lts-need-flu-shotstoo/? php true& type blogs& php true& type blogs& php true& type blogs& php true& type blogs& php true& type blogs& php true& type blogs& r 5 Futurity, Monique Patenaude: Young adults who skip flu shot show most severe symptoms; Feb 11, 2014 o account-severest-flu-cases/ The Herald-Sun, Keith Upchurch; Duke would be ready for Ebola case; Aug 14, 2014 o Duke-would-be-ready-forEbola-case CBS News, ABC News, Marilynn Marchione; Zmapp cures monkeys of Ebola virus; Aug 29, 2014, Associated Press o -ebola-virus/ o e true National Public Radio, Leoneda Inge, Is North Carolina Prepared for Ebola?; October 9, 2014, WUNC 91.5; o http://wunc.org/post/north-carolina-prepared-ebola The Conversation, Even with mismatches flu shots can keep you from getting sick. December 9, 2014 o lu-shots-can-still-keep-youfrom-getting-sick-35151 EverydayHealth.com, Jennifer Brown: 10 Essential Facts about Whooping Cough; published 2015-02-20 o cts-about-whooping-cough/

CBSNews.com, Ashley Welsh: Many Americans with HIV don't know they're infected; June 26, 2015 o v-dont-know-theyreinfected/ WNCN, Emma Wright; Duke specialist says Zika virus currently not a threat in the US, Jan 29th, 2016 o ka-virus-not-currently-a-threatin-us/ TimeWarnerCable News 14, Chris Williams; Duke Doctor: Zika vaccine is years away; Jan 29th, 2016 o html

Full board member of Duke Institutional Review Board, 2009-2013 Co-team leader for two Duke Hospital medical relief missions to Haiti, 2009 Duke University Course in Scientific Leadership and Management, 2010-11 AWARDS and SCHOLARSHIPS: Duke University Hospital Strength, Hope and Caring Award, 2015 (Ebola management team)

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