Cus Bi II - Sartorius

Cubis II Your Balance, Your Way

Cubis II The New Generation ofModular Premium BalancesFor scientists in R&D or analytical laboratories needingthe most reliable lab weighing results, the Cubis IIplatform from Sartorius is a completely configurable,high-performance portfolio of both lab weighinghardware and software. The Cubis II will align with yourunique demands and compliance requirements to helpmaximize your operational efficiency and experimentaloutcomes.The Cubis II platform is the only laboratory balance withfully customizable hardware, software, and connectivity.It offers modern user interfaces, pharmaceutical and GxPcompliance, including data handling, data integrity andconnectivity, ergonomic sample handling, easy processintegration, and unlimited communication at the highestlevel of accuracy and precision.------------Customizable ModularityThousands of hardware and software configurationssupporting your personal preferences.Thematically structured software packages for youroptimized workflows.Seamless connectivity to diverse laboratory informationsystems without the need of additional software.Long-term flexibility guarantees adaptation ofsoftware and accesories to evolving regulatory andlaboratory needs.Intelligence by DesignBuild-in applications guide you through your workflows.Fast and easy leveling guaranteed with automatic,motorized leveling function.Innovative draft shield technology with motion gesturesensor and memory functions.Climate sensor for environmental monitoring.Built-in ionizer for automatic electrostatic elimination.Status Center for user notifications and alerts*.Ultramicro– and micro balances with innovativetechnology for top-edge performance.Confident Compliance*Full data integrity following ALCOA principles.Complete traceability via advanced audit trail andreporting function for efficient reviews.Submission-ready data with remote data selectionon web browser.User management including centralized passwordmanagement support (“single-sign-on” via LDAP),high security password configuration, login rules.Electronic signature in compliance with 21 CFR Part 11.Trusted ResultsLeading PerformanceHigh Speed AccuracyError-Free OperationsFull End-to-End Data IntegrityReliable Support Find out more For more information, please visitwww.sartorius.com/cubis-ii*available with the MCA interface

ratedIonizerWorkflowIntegrationwith QAppsAutomaticMotorizedLeveling

Customizable Modularity –Thousands of ConfigurationsIn 2009, Sartorius offered the first modular balance with theCubis , and today continues that tradition by offering theCubis II, the first lab balance series featuring a completelymodular design:Weighing ModulesChoose from a range of 45 different weighing modules thatbest fit your preferences.Draft ShieldsChoose from 7 different options, depending on yourbalance type – each with unique features to supportmaximal balance performance and user-centric design.DisplayChoose between advanced and essential user interface,based on your weighing applications and requirements.SoftwareWith up to 60 optional software applications clusteredinto QApp packages, and with continuous softwaredevelopment, we support your workflows now and inthe future.010101 Ultra-Micro & Micro BalancesMax. capacity between 2.1 g and10.1 g scale interval with a rangeof 0.1 μg to 1 μg.-Automatic, motorized, round,glass draft shield with learningcapability, illumination andintegrated motion sensor.Manual stainless steel draft shieldfor filter weighing applications. Find out more For more information, please visitwww.sartorius.com/cubis-ii02 Semi-Micro & AnalyticalBalancesMax. capacity between 120 g and520 g scale interval with a rangeof 0.01 mg to 0.1 mg.-Automatic glass draft shield withor without integrated ionizer toeliminate interfering electrostaticcharges on samples and samplecontainers.Manual glass draft shield withsmooth-action doors.03 Precision BalancesMax. capacity between 320 gand 14,200 g scale interval witha range of 1 mg to 100 mg.--Easy to use manual glass draftshield.Removable flat stainless steeldraft shield frame (not shownin the picture).

0603030502020404 MCE Essential UserInterfaceLarge, high-contrast touch displaywith factory-installed essentialweighing applications for easy operation.05 MCA Advanced User Interface06 High-Capacity BalancesLarge 7“ color touch displayincluding touch, scroll, swipefunctionality with factory-installedessential weighing applicationsand diverse QApp Packages foroptional software extension.Max. capacity between 11200 gand 70,200 g scale interval witha range of 100 mg to 1 g.Software OptionsChoose between differentpackages to fulfill your demands.Each package contains powerfulapplications or functions toenhance and individualize yourbalance for your workflows.----QApp Package PharmaQApp Package AdvancedApplicationsQApp Package UtilitiesQApp Package ConnectivityAll Inclusive QApp Package(with new orders only)

Intelligence by Design –Adaptable Lab Balanceto Your Specific NeedsOnboard QApp CenterChoose your applicationsor individual balancefunctions from QApppackages clustered bydifferent topics. Licenseyour selected packageand integrate them intothe tasks you can run onthe balance. Find out more For more information, please visitwww.sartorius.com/cubis-iiAutomatic, MotorizedLevelingAvoid the burdensomeprocess of preparing yourbalance for use with theCubis II balance‘s quickand easy, motorized,auto-levelling function.Gesture ControlThe gesture sensor recognizes four gestures andcan be positioned near thebalance, directly in the flowof motion at your workspace. It allows you to openand close the automaticdraft shield, start the ionizer,or send a document to adevice.Ultra-Micro andMicro BalancesThe world‘s first ultra-microand micro balances withautomatic motorized levelling, gesture controlled andilluminated draft shield, andtitanium inner parts.Weighing ranges from0.1 μg to 10.1 g.

Built-in Ionizer forElectrostatic EliminationRemove balance stabilization frustrations caused byelectrostatic effects withthe built-in ionizing technology of the Cubis IIbalance. Electrostaticcharges on samples andvessels are removed effectively, just by pressing onekey or automatically whenthe draft shield door closes.Climate Monitoring*The climate sensor monitorsinfluencing variables of theenvironment and ensuresthat temperature, pressure,and humidity do not negatively affect your results.* available with the MCA interfaceStatus CenterNotifications*The Status Center showsall information about yourbalance and environmentalconditions, e.g. calibration,leveling, temperature,humidity, air pressure andservice, centralized in adashboard. In case ofwarnings or errors, you getdetailed help and support.Sample HoldersThe great variety of sampleholders ensure that samplesof various types (e.g. safe-locktubes, vials, flask, syringes) canbe weighed directly on thebalance. In this way workflowscan be executed much easier,safer and faster. Made of titanium, not only the highestmaterial quality is guaranteed,but notably the repeatabilityis not jeopardized because ofthe non-magnetic properties.

Confident Compliance –Complete TraceabilityAll data generated by the Cubis II balance follow thekey principles ALCOA ( ), which defines data integritystandards and relates to GxPs. Therefore, the Cubis IIbalance ensures safe and accurate data storage andsupports all requirements for FDA directive 21 CFR part 11and EU Annex 11 compliance.The Cubis II balance, with pharma package, contains allthe technical controls to support compliance with commonregulations. Full compliance can be achieved with additionalprocedural controls and systems for long-term data storage.BackupCubis II can automaticallyexecute time-controlledactions for backup.The system is able to uploaddata on a file share or exportthe data to other systems.Archiving is easily possibleand fully compliant.Fully Compliant Find out more For more information, please visitwww.sartorius.com/cubis-iiSafe Data TransferAn electronic record shouldbe protected against anymanipulation. The Cubis IIbalance saves all files,together with a calculatedMD5 checksum which isstored in the audit trail filesand additionally in a separate MD5 file.

Audit Trail & Alibi MemoryThe Cubis II balance’s audittrail is a tamper-protectedtime-stamped electroniclogfile, that allows reconstruction of events relatedto the creation, modification, and or deletion ofrecords. The data can bedisplayed, filtered, andexported in an easy way.Additionally, the Cubis IIbalance contains an “AlibiMemory”. The system automatically stores weighingdata in a ring buffer.Audit Trail &Alibi MemoryUser ManagementThe Cubis II balanceprovides two options forcomplete user management with access control.The local user managementcan be configured in accordance with your passwordpolicy.The password rules for21 CFR Part 11 complianceare easily implemented.Moreover, Cubis II can beintegrated in the company sdomain to allow single signon. In this case the companydefined password rules areimplemented pSafe Data TransferTime SynchronizationThe Cubis II balancesupports automatic timesynchronization via NetworkTime Protocol (NTP).An accurate time stampis elemental for zationElectronic SignaturesIn the Cubis II balance, anelectronic signature can beused to sign the final reportfor weighing processes.Based on a secure password, the combination ofusername and password isfully compliant with 21 CFR.

Configure Your Cubis II BalanceUser inteface Weighing moduleM C A225SBalance typeWeighing module*Approval– 2S0Draft shield0 –IQApp PackagesQP1 QP2 QP3LevelingApprovalDraft shieldautomatic manualS00, S01, CEU, CFR, CCN, AOBR, OIN, OJP, ORUEFSoftware packages***IMRU0QP1, QP2, QP3, QP4or QP99Ultramicro2.7SMicro10.6S, 6.6S, 3.6PSemimicro225S, 225P, 125S, 125PAnalytical524S, 524P, 324S, 324P,224S, 124SPrecision 1 mg5203S, 5203P, 3203S,2203S, 2203P, 1203S,623S, 623P, 323SPrecision 10 mg5202SPrecision 10 mg8202S, 6202S, 6202P,4202S, 2202S, 1202SPrecision 10 mg32202P**, 14202S,14202P, 10202SPrecision 100 mg5201S, 8201SPrecision 100 mg12201SHigh Capacity70201S, 50201S, 36201S,36201P, 20201S, 11201S,70200S, 36200S Find out more For more information, please visitwww.sartorius.com/cubis-ii* All weighing modules available with MCA or MCE display** Weighing module 32202P available with approvals S00 or S01 only*** Software packages available for balances with MCA display only