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One Gene-One Enzyme Hypothesis (Beadle & Tatum) The function of a gene is to dictate the production of a specific enzyme One Gene—One Enzyme but not all proteins are enzymes those proteins are coded by genes too One Gene—One Protein but many proteins are composed of several polypeptides, each of which has its own gene One Gene—One Polypeptide

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this genotype is caused by more than one gene because there are 4 phenotypes not 3 in F2 (9:3:3:1) Ð1 gene F2 would have 3 phenotypes 1:2:1 ratio Complementary Gene Action : one good copy of each gene is needed for expression of the final phenotype Ð9:7 ratio Epistasis : one gene can mask the effect of another gene

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the non-dominant (recessive) form. Returning to the example of eye colour: brown eyes are more common than blue eyes because the gene for brown eyes is dominant over the gene for blue. This means that whenever the brown eye gene is present, it will overrule the recessive blue eye gene. The same applies to dominant and recessive mito genes.

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