MCQ’s FOR SLE&DHA PHARMACIST EXAM
10/4/2014MCQ’s FORSLE&DHAPHARMACISTEXAMLicensureCOOLONIXRPH
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDS1.Drug is stored in the body120 QUESTIONSa.fatb.proteinc.connective tissued.musclee. a b2. if a drug has the same active ingredient like other drug but not contain the same inactiveingredient this mean:a- Bioequivalentb-pharmaceutical equivalentc- Pharmaceutical alternatived- A,B3. Enkephalins are peptides that:a. have narcotic antagonist activity.b. exert actions resembling those of opiates.c. are found only in the central nervous system.d. cause blood vessel wall relaxation.e. transmit pain impulses4.To know the severity of immunodeficiency in HIV,a. ESRb. Leukocyte countc. WBC countd. CD4 count5. The ethical principle of veracity requires that:a. we respect the rights of others to make choices.b. we act with honesty, without deception.c. we avoid, remove or prevent harm.d. we do good to patients.e. we act with fairness.6. The style of management in which the owner of a pharmacy emphasizes the development ofdetailed policies and written procedures for employees to observe at all times is referred to as:a. autocratic.b. bureaucratic.c. participative.d. benevolent.e. consultative.7- A patient purchasing sublingual nitroglycerin tablets should be told to store the medication:a. in the refrigeratorb. in a plastic vial with a childproof cap.c. with the original cotton.d. in an amber glass bottle with a metal cap.e. in a warm, dry place8- Following the ethical principle of no maleficence requires that pharmacists:a. respect the rights of patients to make choices.b. do good to patients, placing the benefit of the patient above all else.Page 1 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSc. avoid, remove or prevent harm from people.d. act with fairness, allowing people access to pharmacy care.e. act with honesty, without deception.9- prep. containing coal tar 30 part petrolatum 15 part adeq. to 150 part what conc. Ofpetrolatum in 500ml:30 parts 15 parts are in total 150 parts15 parts of petroleum are in 150 partsX parts-------------------------500ml, x 15*500/150 50 parts of petroleum10. Hydroxyurea is:Used to treat sickle cell disease, polycythemia vera, myloproliferative neoplasm (bone marrowcancer)11. Which one of the following Estrogens Taken Orally:a. Estrogenb. Estrogen Gluconatec. Estrogen Malated. All of above12. The responsibility of pharmacist in hospital is to deal witha- administration of drugb- deal with patientc- deal with drug interactiond- notice effect of drug13.Plasma concentration of drug in bodya- rate of absorptionb- rate of distributionc- rate of bindingd- therapeutic volume14. The following statements are wrong about domperidone excepta- anti-emetic without CNS effectb- anticoagulantc- anti-emetic with sever CNS effectd- non of the above15. You should keep the prescription of narcotics in the pharmacy fora- two yearb- three yearsc- four yearsd- five years16. Pka of normal water at room temperature isa. 7b. 14c. 10 7d. 10 14e.10 -1417. drug make urine red other than rifampicin: Given in Table belowPage 2 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSUrine discoloration / UrinalysisUrine discolorationDark / BrownCascaraChloroquineferrous salts/ iron rofurantoinPrimaquineSennaSulfonamidesBlue or blue greenamitriptylinemethylene nsulfasalazinewarfarinRed / Pinkdaunorubicin or . Syncope may occur at first dose of followinga.Digoxinb. SalbutamolPage 3 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSc. Prazocind. Reserpinee. Clinodine19. Which one is more effective against traveler’s diarrhea quinolones have been the drug ofchoice:a amoxiciilinb.ciprofloxacinc sulphamethoxasold erythromycin20. Antihypertensive produce Atenolole)Clonidine21. the action of digoxin can reduced witha antacidb verapamilc.hypokalemiad hypothirodisme hyperthyrodism22. the main cause of digitalis toxicity isa diabetes millib hypertensionc hepatitisd.renal failure23. digitalis arrhythmia can be treated witha lidocaineb quinidinec procainamided propranolol24. which one used in ventricular arrhythmia with heart blocka.Phynetoinb. procainamide25. which one is antiarrythmic class 1Aa phenytoinb disopyramidec propranolold verapamile propafenon26- anti cancer derived from vinka Alkaloids isa cyclophosamideb flourouracilc doxurubcind.cicplastinPage 4 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSe. none of above27. which one used to trigeminal neuralgia: tegretol (Carbamazepine)28. the solution contain 9ppm of NaCl the the concentration of the compound in the solutiona 0.9b .09c .009d .0009e .00009Calculation:1ppm 1000000, 1 Percent 1/100,1ppm into Percent 100/1000000, 0.0001% or 1/100009ppm 9/10000, 0.0009%Formula for % ppm/1000029- Process require EAMINATIONe)SULFERATION30- Adsorption , which is not true:a) Chemical propertyb) Physical propertyc) Reversibled) Irreversiblee) A d31- about steady state concentration during IV administrationa directly ptoportional to volume of distributionb inversly proportional to volume of distributionc directly ptoportional to infusion rated inversly proportional to total body clearancee c&d32- which of the following decrease gastric emptying ratea metoclopramideb atropinc hypothyrodismd a&be b&c33- one of following is not alpha 2 agonist:a) Clonidine alphab) Alpha methyl noradrenaline (Nonselective, acts on Beta1, alpha1 2)c) Guanfacined) Guanabenze) Guanethidine34- about side effect of quinidine:CinchonismPage 5 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDS35. about digitoxin , which is false:a) Oral bioavailability 100%b) Protein binding 95%c) Half life is 7 daysd) Mainly hepatic metabolism by microsomal36- Volatile substance given by inhalation:Halothane37- to compare between 2 drugs use:a) Physical appearanceb) Weightif comparing bioequivalencyc) Pharmacokinetic parameters if effectd) Pharmacodynamics parametere) Taste38- about side effect of oral contraceptive except:a) Depressoinb) Hypertensionc) constipation39- drug used in ventricular arrhythmia:a) Phenytoinb) Quinidinec) Digoxind) Procainamidee) Verapamil40- in tolerance patient need more dose to obtain the same effect41A- Causes of hypothyroidism:: iodine deficiency , low hypothulmus & pituitary hormons41B- phenytoin uses other than anticonvulsant agent are: ttt irregular heart beat & ttt painfulnerve conduction (neuralgia) , Class 1B Antiarrythmic.42- Arrhythmia due to :Dysfunction in generate heart pulse or conduction of it43- Hydralazine, vessel relaxation.It dilates arterioles more than veins.44- Guanthedine SE are alla-prevent ejaculationb. orthostatic hypotensionc- diarrhea45- not from WBCa. reticulocyteb. Leukocytec. lymphocyte46- about minoxidila - it decrease myocardium contractilityb - dilate arteries onlyc- cause bradycardiaPage 6 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDS47- mizolastinea- antibioticb- anticoagulantc - anti plateletd- non-sedating antihistaminic48- all these drugs are anti-metabolite except:Cisplatin49- about digioxin what is not truetaken only orally50- Captopril and Enalapril do all the following except:a. increase renin concentration in bloodb. Inhibit an enzymec. competitively blocks angiotensin 2 at its receptorsd. Raises blood potassium conc.(Hyperkalemia)51- Various opiates may be used as all of the following except:a- Analgesicsb- Anti inflammatoryc- Antidiarrheald- Aids to anesthesiae- Antitussive52- Which of the following action is not seen with sympathomimetic?a- Pupil constrictionb- Increased heart ratec- Bronchiole dilationd- Systemic blood vessel constriction53- Which of the following beta-adrenergic agents is not short acting?a- Pirbuterolb- Salmetrolc- Terbutalined- Albuterole- None of the above54- Which of the following drugs is not a Tricyclic Antidepressant?a- Trimipramineb- Maprotiline (tetracyclic)c- Nortyptyllined- None of above55. Most common disintegrator in compressed tablets isa. Dextroseb. Lactosec. Starchd. potassium bitartaratee. powdered sucrose56. Which of the following is found in Vitamin B12a. Magnesiumb. IronPage 7 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSc. Cobaltd. Sodium57. Gums are used in Tableting Primarily asa. Disintegratorsb. Glidantsc. Lubricantsd. Binding Agentse. both b & c58. Cyclosporine is used fora. allergiesb. anginac. prevention of transplant rejectiond. steroid deficiencye. treating lead poisoning59- Ultra-short acting barbiturates are used primarily asa- Sedativesb- Hypnoticsc- Antispasmodic agentsd- Anti-parkinsonian agente- Pre-anesthetic agents60- for a 4 year old child, the maximum daily dose of Paracetamol isa- 240mgb- 480 mgc- 1 gd- 2 g60- To supply the myocardium with O2 shortly after myocardial infarction we - - Which one of the following cannot be dispensed without prescription:a- Ibuprofenb- Doxycyclinec- Aspirind- Bisacodyl62- - The aim in the management of uncomplicated hypertensiona- 90/65b- 130/85c- 150/95d- 180/11063- A hospital on formulating drugs, Efficacy, Work overload, and Costs are taken in concern. A,B, C, D, and E are antifungal drugs available in the market. All have the same efficacy. Thehospital was using drug E for a period of time. According to the following data which drug isbest to be used by the hospital?DRUG COST FREQUENCY DURATIONPage 8 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSA 3.25 BID 14 DAYSB 2.25 ONCE DAILY 14 DAYSC 5.5 BID 7 DAYSD 2.25 BID 7 DAYSE 3.00 QID 7 DAYSA.91 dollar,B. 31.5 dollar, C.77 dollar, D.31.5, E,84 dollarD is most economical and because pharmacy has less staff so it can be managed easily64- Solid dosage forms are better than Solution dosage form because:a- Accurate doseb- Easy to handlec- More stabled- Faster actione- a & b and c65- Tolerance is a problem when using Nitroglycerin, which of the following is true:a- Tolerance doesn't occur in young patientb- Over 50 years patient doesn't develop tolerancec- Dosing schedule may affect toleranced- Isosorbide dinitrate doesn't develop tolerance66- arranging the electro magnetic waves in an increase ranking in air will bea. alpha,beta,gammab-beta,gamma, alphac-gamma,,alpha,,betad-alpha,,beta negative,,,gamma,,,beta positive67- Gray man syndrome due toamiodarone68- - indapemide used inPulmonary eodemaEssential hypertensionAngina pectoris69- one of the followimg not related to heparina-prevent blood clottingb.decrease antithrombine timec-prevent formation of factor VIId-used in pulmonary emboliiWarfarin affects the vitamin K-dependent clotting factors (II, VII, IX,X) , whereas heparin andrelated compounds increase the action of antithrombin on thrombin and factor Xa70 - Which not effect of caffiene:a)peripheral vasoconstrictionb)cardiac stimulationc)diuresisd)skeletal muscle relaxante)stimulation of C.N.S71- -Hypertonic solutions can be adjusted by:a-Add Nacl salt to solutionb-add any other saltPage 9 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSc-Make dilution by add more solventd-This solution can not be adjustede. None of above72- - entero Hepatic recycling depend on all of the following except:a-Dosage form of the drugb.Extent of drug passed in feacesc. extent of drug absorption from stomachd-gall bladder state73- -if we have a solvent costs 150 riyal/kg and its specific gravity 1.07 ,so the cost for 100 mlof the solvent is?16.05150 is price of 1000ml 1kg, x-----------100ml, x 100*150/1000 15, 15*1.07 16.05 Riyal74- which of the following drugs show most multidrug resistance:a). Almost all drugs show some resistanceb)antibioticsc)anticancerd)a&b75- . The following liquids are least likely to be miscible:A. polar polarB. non-polar polarC. non-polar non-polarD. all of the above will be miscibleE. Band C76- At 25 C, benzoic acid is much more soluble in benzene (C6H6) than it is in water. In thissituation benzoic acid could be considered to be: A. HydrophilicB. ColloidalC. Non-polarD. PolarE. Both A and D77- The following properties are similar for both solutions and suspensions:A. The components of both solutions and suspensions can be separated from each other byphysical processes. .B.Solutions and suspensions are composed of two or more componentsC. Solute in the solutions and suspensions settle out over a period of time.D. Both A and BE. Both Band C78- Concerning COX-2 inhibitor, which is not true?A. they have lower risk gastric adverse reactions than non-selective agentsB good evidence about their effectiveness in osteoarthritisC. cardiac toxicity is a recent concern of this class of drugsD. they are. usually administered once or twice dailyE. combination with non-selective agents provide additional benefit79- In the treatment of the osteoporosis, which of the following is not correct:A. alendronate should be taken in the morning 60 min before breakfastB. calcium and vitamin D are essentialPage 10 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSC. hormone replacement therapy (HRT) should be considered in all postmenopausal patientswith osteoporosisD. outcome should be assessed with periodic bone density studiesE. raloxifene is selective estrogen modulator that is contraindicated in DVTpatients80- Side effects of albuterol include which of the following?A. BradycardiaB. TachycardiaC. ConvulsionD. HypotensionE. Alopecia,81- . Which of the following side effects is associated with the use of norepinephrine:A. Nausea and vomiting.B. Ischemic damage due to vasoconstriction and tissue hypoxia.C. Hypoglycemia due to increase insulin release.D. Skin rashes.E. Headache and constipation.82- the pharmacological property of amphetamine is:A. Causes release of estrogen.B. Causes release of stored norepinephrine.C. Does not cross the blood brain barrier.D. Causes the release of stored acetylcholine.E. Metabolized by phosphodiesterase II.83- Which of the following statements describing first dose phenomenon that associated withprazosin is true? .A. A marked increase in the level of glucose following the initial dose of prazocin.B. A marked decrease in the level of glucose following the initial dose of prazocin.C. A marked increase in the level of cholesterol foilowing the initial dose of prazocin.D. A marked postural hypotension 30 to 90 minutes following the initial dose of prazocin.84- all the following diazoxide side effects ricemiae- hypotension85- which one causes hypotension due to blockage of efferent limb baroreceptor reflexa- bretyliumb-phenytoinc- ranitidined.amphetaminee.isopreterinol86- wich statment about radiation parameters or units is falsea.Becquerel is the transformation (disintegration) rate of a radioactive substanceb.Gray (Absorbed dose) is a physical quantity which represents the energy imparted byradiation onto an absorbing material.c.Roentgen (Exposure) is a quantity that expresses the ability of radiation to ionize air andPage 11 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSthereby create electric charges which can be collected and measured.d.none of the above*87- thiopental is?a ) short acting barbituratesb ) long acting barbituratesc ) spinal anaesthesiad ) antihistaminice ) antibiotic88- which of the following is not macrolide antibiotic?a ) erythromycinb ) spiramycinc ) chloramphenicold ) clarithromycine ) azithromycin89 - 3 ) amount of drug is 5 mg in 1 ml what the amount of drug in 1 tsp in micrograma) 5b ) 25c ) 500d ) 2500e ) 25000 (25mg in 5ml(1TSF)90- Digoxin action except:a- ve inotropicb-shorten refractory period in atrial and ventricular myocardialc-increase conduction velocity in AV noded-contraction of myocardial muscle91- Milironin has following except:a- ve inotropicb-vasodilatorc.increase ca intercellulard.phosphodiasterase inhibitore.blocks Na/K Activated ATPase92a-increase the distance from radiation sourceb-out from the place of radiationc.put shelvesd-decrease the activity of radiation person93- how many gm of water add to 5% KCL soln to make 100 gm of solution(w\wa-95b-90c-80d-7594- Very small molecule (1 part ) soluble in more than 10,000 part of watera- fairly solubleb-Very slightly solubleC-immisciblePage 12 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSd- misciblee- insoluble95- Which one of the following cause hypertensive crisis if withdrawn suddenlya.Clonidineb.hydrochlorothiazidec-blocker prazocin96- which one is not effect of Nitroglycerina. vasodilationb.relax of biliay musclec.slow heart rated.taken sublinguallye.decrease blood pressure97- drugs have different crystal structures so different ina-polymorphismb.solubilityc-crystalitisd-drug form98- which of these have intrinsic sympathomimetics anlolNote: Pindolol& Acebutolol both have Intrinsic Sympathomimetic Activity(ISA).Inspite of Beingblockers,they also stimulate Adrenergic receptors to some extent.99- protect from light" in USP means:a- air tight containerb- plastic containerc- Light resistant containerd- Amber glasse- Amber plastic100 - DAILY intake of vitamin A for adult female is:a-500 mcgb-700 mcgc-1500 mcgd-1mgNote: For Males it is 900mcg101- -most potent anti-inflammatory corticosteroid systemically dnisonee-dexamethasone102- -suspension eye drop differ than ophthalmic solution in:a-less commonly usedPage 13 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSb- decrease contact time of drug with eyec- used for insoluble drugsd- a&c103- Cushing - like syndrome is due toa) adrenal hyperplasiab) adrenal hypoplasiac) Hypothyroidismd) hyperthyroidism104- - Morphine causes respiratory depression bya) depression of respiratory center in brainb) activation of respiratory center in brainc) depression of CTZ receptors center in braind) activation of CTZ receptors center in brain105. Calcium-channel blockers mode of actiona) increase the inward calcium to cellsb) decrease the inward calcium to cells106. -which is (are) electromagnetic wavesa)X-rayb) Beta- rayc) Gama- rayd)a c107- -Phenylepherinea.used in nasal decongestantb-in high doses stimulate beta adrenergic receptorc.not substrate for chatechole o methyltransferase ( COMT)d-all of the abovee.both a and c108- One of the statement considering Tetracaine One of neuro muscular blockera-In the ttt of T.Bb-Opioid analgesicc-Vit d metabolited-The most one of choice in spinal anaesthesia109- Neuromuscular blocker is used of choice in renal and hepatic failure:A -tubocurarine.B - Vecuronium.C -pancuronium.D -gallamine.E – atracurim (Cis-Atracurium)110- enzyme kinetics law:A - Michaelis–Menten lawB -henry s law.C -franks law.D - Henderson hasselbach lawE - b&c111- -amphetamine pharmacological action:Page 14 of 416
MCQ’s FOR SLE & DHA PHARMACIST LICENCING EXAMSRph.UK STANDARDSA - direct acting adrenergic agonist.B -direct acting adrenergic antagonist.C - indirect acting adrenergic agonist.D - indirect acting adrenergic agonist.E –muscarinic acting agonist112.- 0.8687 g cacl2 in 500 ml solvent, density of the solvent 0.95g\cm3.Find the molalitya- 0.0165 Molalb- 0.0156 Molalc- 0.0165 md- 0.0156 me- 0.0230 mMolarity no. of moles of solute/Liter of SolutionStept1 determine no. of molesMolecular weight of Cacl2 1110.8687g/111g 0.007826 moleStep2 determine mass
MCQ ’s FOR SLE & DHA PHARMACIST LICENCING EXAMS Rph.UK STANDARDS Page 2 of 416 c. avoid, remove or prevent harm from people. d. act with fairness, allowing people access to pharmacy care. e. act with honesty, without deception.
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0452 ACCOUNTING 0452/21 Paper 2, maximum raw mark 120 This mark scheme is published as an aid to teachers and candidates, to indicate the requirements of the examination. It shows the basis on which Examiners were instructed to award marks. It does not indicate the details of the discussions that took place at an Examiners’ meeting before marking began, which would have considered the .
