MUSCLE TISSUE Inspection Questions

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MUSCLE TISSUEInspection questions1. General characteristic muscle tissue.2. Classification of the muscle tissues.3. General characteristic of smooth muscle tissue.4. Structure of smooth myocyte.5. Mechanism of contraction of smooth muscle cells.6. Histogenesis of smooth muscle tissue.7. Regeneration and innervation of smooth muscle tissue.8. General characteristic of skeletal muscle tissue.9. Structure of the muscle fibers.10. Contractile apparatus of muscle fiber.11. Structure of myofibril, sarcomere.12. Mechanism of muscle fiber contraction.13. Histogenesis, innervation and regeneration of skeletal muscle tissue.14. Structure of muscle as an organ.15. General characteristic cardiac muscle tissue.16. Types of cardiac muscle cells.17. Typical cardiac muscle cells: structure and function.18. Secretory cardiac muscle cells: structure and function.19. Counductin system of the heart. Characteristic of its cells.20. Histogenesis, innervation and regeneration of cardiac muscle tissue.Question 1. General characteristic muscle tissue.Muscle tissue is responsible for movement of the body and its parts and for changes in the size andshape of internal organs. This tissue is characterized by aggregates of specialized, elongated cells orstructures arranged in parallel array that have the primary role of contraction.Two types of myofilaments are associated with cell contraction. They are more thine actinfilaments consisting of contractile protein actin and more thick myosin filaments consisting of contractile protein myosin.Cytoplasm of muscle cells is called sarcoplasm, outer covering of muscle cells is calledsarcolemma.In sarcoplasm of muscle cells there are all general organelles of cell, but more developing aremitochondria and smooth endoplasmic reticulum.In muscle cells the smooth endoplasmic reticulum is called sarcoplasmic reticulum. It providesaccumulation and realization of calcium necessary for contraction. Mitochondria produce ATPnecessary for contraction also.Question 2. Classification of the muscle tissues.

Question 3. General characteristic of smooth muscle tissueSmooth muscle tissue arises from mesenchyme.Smooth muscle tissue is found in the walls of internal organs, ducts of glands and in walls of mostvessels.Structural and functional unit of smooth muscle tissue is named smooth muscle cells or smoothmyocyteQuestion 4. Structure of smooth myocyte.Smooth muscle cells are long spindle shaped cells, having a broad central part and tapering ends. Inroutin H&E preparations the smooth muscle cell sarcoplasm is stained oxyphilically with eosin, becausecontains high concentrations of actin and myosin contractile proteins.The band like nucleus is located in the center part of the smooth muscle cell. At nuclear polethe sarcoplasm of the smooth muscle cell contains mitochondria, a Golgi complex, endoplasmic reticulum,free ribosomes.Smooth muscle cells possess a contractile apparatus presenting by thin actin and thick myosinfilaments and a cytoskeleton presenting mainly by intermediate filaments.The bundles of thin actin filaments crisscross through the cell, forming a three-dimensionalanastomosing network. They are attached to the irregular electron-dense bodies presenting insarcoplasm of smooth muscle cell. There are 2 type of dense bodies – membrane-associated andcytoplasmic. Dense bodies contain a protein α-actin. Actin filaments are anchored to the dense bodiesby only one end. Increasing of the Ca level inítiates formation of myosin filaments, which are polymerizedbetween free ends of actin myofilaments. The intermediate filaments that are attached to dense bodiesalso consist of proteins called desmin and vimentin.Thus, the dense bodies anchors both thin filaments and intermediate filaments either directly orindirectly to the sarcolemma of smooth muscle cells.

Sarcolemma of all muscle cells including smooth muscle cells consists of two layers:1) Internal lamina or plasma membrane;2) External lamina or basal lamina.Each smooth muscle cell is surrounded by

This type of muscle tissue belongs to the striated because muscle fibers contain striated myofibrils. Question 9. Structure of the muscle fibers. Muscle fiber is long, cylindrical structure. Each muscle fiber is really a symplast or syncytium with hundreds of nuclei along its length.

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