Epidemiology And Population Sciences

ENQUIRE Cluster 17Epidemiology and Population SciencesValerie Durrant, Ph.D.Director, Division of AIDS, Behavior and Population Sciences27 September 2021

SRGs Under Review in Cluster 17 Behavioral Genetics and Epidemiology (BGES)Biostatistical Methods and Research Design (BMRD)Cancer, Heart, and Sleep Epidemiology Panel A (CHSA)Cancer, Heart, and Sleep Epidemiology Panel B (CHSB)Clinical Research & Field Studies of Infectious Disease* (CRFS)Genetics of Health and Disease (GHD)Infectious Diseases, Reproductive Health, Asthma andPulmonary Conditions* (IRAP) Kidney, Nutrition, Obesity, and Diabetes (KNOD) Neurological, Aging and Musculoskeletal Epidemiology* (NAME)(*and overflow SEPs)

External Panel Recommendations (May 2021)Key issues identified:General recommendations: All panels large and growing From 9 to 14 study sections Current scope defined by healthoutcomes has limitations Conceptual framework that reflectsmulti-dimensional focus of field Odd disease/expertise combinationsthat lack scientific logic Three domains: health states,“exposures”, and methods Not aligned with state of the science –overemphasizes outcomes Emphasis on study section overlap What to do with studies with multipleoutcomes, multi-morbidities, or otherstudies that straddle study sections. Names/descriptions uneven, lackattention to key aspects of science,including some cross-cutting issues Intentional integration of innovativeconcepts, methods and critical aspectsof epidemiology/population scienceacross all

External Panel Recommendations

Internal Panel Recommendations (Sept 2021) General approach provides a good structure for study sections Support recommendations with minor caveats Population-based Research in Infectious Disease too big; split along scientific lines 3 methods study sections: reduce to 1-2 (more breadth of expertise in each) Dermatology, Injury, Musculoskeletal and Rheumatology and Kidney, Endocrine, andDigestive Diseases may be too small (science fit is reasonable; enough apps?) Clarify Genetics and Molecules, Life Course and Aging Refine descriptions of all to incorporate language/aspects relevant to science in eachand incorporate attention to clinical epi, social determinants of health, methods, andage. Review process assessment: No concerns– Request to watch closely the potential dispersion of expertise across study sectionswith feasibility tests/implementation.

CSR Proposed study sections Behavioral Genetics & Epi Cancer Heart and SleepEpidemiology (A & B) Clinical Research & Field Studies Kidney, Nutrition, Obesity &Diabetes Infectious, Reproductive, Asthmaand Pulmonary Conditions Neurological, Aging, andMusculoskeletal EpidemiologyMethodsExternal Panel Cancer and Hematological DisordersCardiovascular and Respiratory DiseasesDermatology, Injury, Musculoskeletal, andRheumatologic DisordersKidney, Endocrine, and Digestive DisordersNeurological, Mental, and Behavioral Health Genetics of Health andDisease Biostatistical Methodsand Research DesignPost-Internal Panel Cancer and Hematological DisordersCardiovascular and Respiratory DiseasesDermatology, Injury, Musculoskeletal, and RheumatologicDisordersKidney, Endocrine, and Digestive DisordersNeurological, Mental, [and Behavioral] Health Reproductive, Perinatal, and Pediatric HealthReproductive, Perinatal, and Pediatric Health Aging, Geriatric, and Life CourseLifecourse and Aging Population-based Research in Infectious DiseasePopulation-based Research in Infectious Infectious Disease Ecology and DiagnosticsDiseaseLifestyle and Health Behaviors Lifestyle and Health BehaviorsSocial and Environmental Determinants of Health Social and Environmental Determinants of Health Genes and Molecules for Population Health Population Genetics and Genomics (Discovery) Simulation and Prediction in PopulationHealthBig Data Analytics and Algorithms inPopulation HealthStudy Design and Statistical Approaches inPopulation Health Modeling and Statistical Approaches in PopulationHealth (including infections disease modeling)Data Analytics and Algorithms in Population Health ExposuresHealth StatesCurrent *Study sections names are tentative

Next steps CSR Advisory Council approval?Refinement of study sections/mock sortsFinalize descriptions and overlapsPost new descriptions on CSR websiteFirst submission datesFirst review meetingsSep 2021Oct/Nov 2021Dec 2021Feb 2022June 2022

CSR Advisory Council: Approve?

Cancer, Heart, and Sleep Epidemiology Panel A (CHSA) Cancer, Heart, and Sleep Epidemiology Panel B (CHSB) Clinical Research & Field Studies of Infectious Disease* (CRFS) . 3 methods study sections: reduce to 1-2 (more breadth of expertise in each) Dermatology, Injury, Musculoskeletal and Rheumatology and Kidney, Endocrine .