Dry Granulation Chilsonator

DRY GRANULATION CHILSONATOR CCS 1025 CONTAINED CHILSONATOR SYSTEM THE FITZPATRICK COMPANY

MODEL CCS 1025 CHILSONATOR CCS 1025 DESIGN CONCEPT OVERVIEW Sealed technical area “Free-standing” or “in-wall” installation Integrated roll process housing and milling system minimizes headroom requirement Utilities enter technical area from the back of machine Floor mounted CCS 1025 CONTAINED CHILSONATOR SYSTEM (CCS) The CCS 1025 is designed to fully contain all product in the processing and receiving sections of the machine. This tightly sealed design allows for the optional product containment system (PCS) to be added at the discharge. The PCS draws a slight vacuum in the process environment to provide maximum containment. 2 Red cropmarks: European size—42 cm x 29.7 cm with 1 fold at center, making folded size 21 x 29.7 cm. Black cropmarks: U.S. size—17 in. x 11 in. with 1 fold at center, making folded size 8-1/2 x 11 in.

Spray Spray Spray & Drain CCS 1025 IS DESIGNED FOR OPERATOR CONVENIENCE Ease of disassembly is considered in the design of ALL components In-wall CCS 1025 Wash-In-Place (WIP) option (see illustrations above) Automated controls allow ALL adjustments to be made from the control panel (see pg. 5) Advantages of the Product Containment System: Minimal product exposure to operator and environment Prevents product contamination Minimal product loss The PCS can be combined with an N2 inerting system in order to reduce product oxygen exposure and explosion risks. Containment valves (not shown) required for containment during feed and discharge. 3

EASILY CONFIGURABLE FEED SYSTEM VARIOUS ROLL SURFACES AVAILABLE The Fitzpatrick feed system delivers material to the rolls utilizing a feed hopper, horizontal feed screw for metering material, and a vertical pre-compression screw for pre-compression, deaeration, and transport of feed material to the compaction rolls. The cantilever design allows for easy removal of roll shells for cleaning or reconfiguration. The roll shells have water cooling capability. The high speed vertical pre-compression feed screw(s) is very effective at deaerating a vast majority of powders. Even many low bulk density powders are able to be effectively conditioned for efficient compaction. This feed system design provides significant process advantages with few components to clean and maintain. In a few applications, the material characteristics restrict the ability of the entrained air to be vented from the system utilizing the pre-compaction screw alone. In these applications, the optional Vacuum Deaeration System is available to assist in drawing the entrained air from the product. Vacuum filters can be installed in various locations and a vacuum pump system is utilized to forcibly remove entrained gas from within the product. Process improvements can be dramatic with respect to both compaction efficiency as well as capacity. TWIN OR SINGLE PRE-COMPRESSION SCREW OPTIONS Optional Vacuum Deaeration System VACUUM PUMP SYSTEM Feed hopper includes agitator 4 Twin pre-compression feed screws provide uniform force Single pre-compression feed screw Red cropmarks: European size—42 cm x 29.7 cm with 1 fold at center, making folded size 21 x 29.7 cm. Black cropmarks: U.S. size—17 in. x 11 in. with 1 fold at center, making folded size 8-1/2 x 11 in.

TWO-STEP CONFIGURABLE SIZE REDUCTION The most efficient method of reducing the compact to the desired granule is product dependent. Some applications favor the bar rotor and some favor the knife rotor as more effective. Both options are available on each machine so the optimum arrangement for every product can be configured. In either case, the initial breaker combined with the very large screen area of the secondary reducer provides for the most efficient size reduction. Bar rotor for slow speed “crushing” of compact Knife rotor for “in air” impact size reduction FULLY AUTOMATED CONTROLS Automatic operation of all components from the operator interface Fully instrumented with convenient display and logging of variables 21 CFR part 11 compliant capable Multiple layers of password security 5

CONVENIENT DISSASSEMBLY FEED SYSTEM Components conveniently disassemble from the machine or can be removed as a unit for remote disassembly ROLL SYSTEM Easy roll shell removal 6 Hydraulic system spreads rolls 10mm for cleaning Double lip seal ensures technical area remains sealed while primary seal is removed for cleaning Red cropmarks: European size—42 cm x 29.7 cm with 1 fold at center, making folded size 21 x 29.7 cm. Black cropmarks: U.S. size—17 in. x 11 in. with 1 fold at center, making folded size 8-1/2 x 11 in.

SYSTEM CONFIGURATION BIN-TO-BIN PROCESSING A typical Chilsonator installation would involve feeding material from an initial bin, through the Chilsonator and 2-Step Size Reduction System, and into a product-receiving bin. LS Feed Overs Fines Feed Product Product RECYCLE SYSTEM A recycle system is essentially used for eliminating all fines and overs from the product. A typical recycle system includes the compactor, granulator, screener, fresh feeder, and mechanical or pneumatic conveyor. Additional instrumentation such as level sensors are also required. 7

THE FITZPATRICK COMPANY A TRADITION OF INNOVATION IN PARTICLE FORMING TECHNOLOGY Since the 1930’s, Fitzpatrick has been pioneering the development of particle forming technology. With the development of the Chilsonator Roll compactor in the late 1950’s, Fitzpatrick has been constantly improving this dry agglomeration technology. Both improving existing processes as well as opening up new and difficult applications to the many cost and processing benefits of dry agglomeration, Fitzpatrick continues to uphold their tradition of innovation. Pharmaceutical, chemical, food, plastics and other industries utilize a wide range of Fitzpatrick machines, including FitzMill Comminutors, Fitz cM Classifier Mills, Chilsonator Roll Compactors, FitzSieve for gentle milling and sieving, Malaxators , Homoloid machines and pre-breaking equipment. Each unit is built to stringent quality standards to operate under the most demanding manufacturing conditions. The Fitzpatrick Company maintains manufacturing facilities, test laboratories, and service and support offices in Elmhurst, Illinois; and additional testing, sales, and support services are provided from our office in Sint-Niklaas Belgium. THE FITZPATRICK COMPANY CORPORATE HEADQUARTERS FITZPATRICK EUROPE N.V. 832 Industrial Drive Elmhurst, IL 60126 USA Phone: 630-530-3333 Fax: 630-530-0832 E-mail: info@fitzmill.com Entrepotstraat 8 B-9100 Sint-Niklaas, Belgium Phone: 32 (0)3 7806200 Fax: 32 (0)3 7661084 E-mail: info@fitzpatrick.be Visit us on our web sites : www.fitzmill.com For Europe: www.fitzpatrick.be CCS 1025 04/10 Red cropmarks: European size—42 cm x 29.7 cm with 1 fold at center, making folded size 21 x 29.7 cm. Black cropmarks: U.S. size—17 in. x 11 in. with 1 fold at center, making folded size 8-1/2 x 11 in.

Visit us on our web sites : www.fitzmill.com For Europe: www.fitzpatrick.be CORPORATE HEADQUARTERS 832 Industrial Drive Elmhurst, IL 60126 USA Phone: 630-530-3333 Fax: 630-530-0832 E-mail: info@fitzmill.com FITZPATRICK EUROPE N.V. Entrepotstraat 8 B-9100 Sint-Niklaas, Belgium Phone: 32 (0)3 7806200 Fax: 32 (0)3 7661084 E-mail: info@fitzpatrick.be