Real-time Transfer Specification - Iowa

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Iowa Immunization RegistryInformation System (IRIS)HL7 2.4 – Real-time Transfer SpecificationVersion 1.0Last Updated: January 07, 2013

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0Table of ContentsIntroduction . 3Data Formats Accepted . 3Real Time Processing . 3Web Services . 3PHINMS . 4Outline of real time message types and segments . 5VXU - Unsolicited Vaccination Update . 5VXQ - Query for Vaccination Record . 5VXR - Response TO Vaccination Query Returning the Vaccination Record . 5VXX - Response TO Vaccination Query (Returning Multiple PID Matches) . 5ACK - General Acknowledgment . 5QCK - Query General Acknowledgment . 5Details of real time message types and segments . 6MSH – Message Header Segment . 6VXU – Unsolicited Vaccination Record Update . 6VXQ – Query for Vaccination Record . 6QRD – Query Definition Segment . 7QRF – Query Filter Segment – (REQUIRED by IRIS) . 8VXR – Response TO Vaccination Query (Returning the Vaccination Record) . 9VXR segment detail . 9VXX – Response TO Vaccination Query (Returning Multiple PID Matches) . 10ACK – Acknowledgment Messages (with Errors) . 11MSA – Message Acknowledgment Segment . 11ERR – Error Segment . 12QCK – Query General Acknowledgment . 12MSA – Message Acknowledgment Segment . 12QAK – Query Acknowledgment Segment . 13Appendix A – HL7 Data Types . 14Appendix B – HL7 Tables . 14Appendix C – Vaccine Codes . 14Change History . 142 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0IntroductionThank you for your interest in electronic data exchange with IRIS. Getting immunization data into IRIS isimportant for your clinic and for the individuals you serve. IRIS is interested in finding the least burdensomemethod for your organization to submit data to IRIS.Iowa’s Immunization Registry Information System, IRIS, has made available an interactive user interface onthe World Wide Web for authorized users to enter, query, and update patient immunization records. TheWeb interface makes IRIS information and functions available on desktops around the state. However, someimmunization providers already store and process similar data in their own information systems and maywish to keep using those systems while also participating in the statewide IIS. Others may have differentneeds and may decide they don’t want to enter data into two diverse systems. For many clinics electronictransfer is the preferred method to accomplish this goal.This document explains required and preferred files and data elements and cites several links to assist you indetermining if electronic data transfer is a viable option for your clinic. Please share this document withtechnical staff and/or your software vendor.Data Formats AcceptedData is typically pulled from Electronic Health Record (EHR) systems or from Practice Management systems.IRIS currently accepts the following electronic file types: Fixed format flat text files Health Level Seven (HL7) Version 2.4 standard files Health Level Seven (HL7) Version 2.4 Real Time TransferIRIS accepts and transmits the Health Level Seven (HL7) Version 2.4 Real Time Transfer messaging forsubmitting patient and immunization information to IRIS. This documentation deals with submitting an HL72.4 formatted VXQ V01 message (Query for Vaccination Record) and a VXU V04 message (UnsolicitedVaccination Update) and receiving from IRIS the resulting HL7 2.4 Response Message in real time.Real Time Processing“Real time” processing refers to the ability to transmit an HL7 2.4 formatted VXQ V01 Message (Query forVaccination Record) and a VXU V04 Message (Unsolicited Vaccination Update) and receive from IRIS theresulting HL7 2.4 Response Message in real time. A provider organization will query the registry to getinformation on a certain client (i.e. send an HL7 2.4 VXQ V01 message) and will receive an HL7 2.4 MessageResponse (i.e. VXR V03, VXX V02, ACK or QAK) to that query in real time.Web ServicesWeb Services will require installing a working web service client to enable interoperability between our javabased, real-time codebase, and the various web service clients designed/implemented by the participants.The underlying web service operation will be defined to be generic, and can exchange HL7 2.4 Messages andtheir appropriate Message Responses. The HL7 2.4 vaccination query (VXQ V01) or HL7 2.4 UnsolicitedVaccination Update (VXU V04) transactions and their Response Messages will be utilized under the sameweb service interface. The web services security and other technologies will be communicated via WebServices Policy statements, in addition to Web Services Security Policy statements which will in our case becontained with the WSDL document for the defined web service.3 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0IRIS will use Simple Object Access Protocol (SOAP) to exchange messages using an Extensible MarkupLanguage (XML) format. To get a more in-depth understanding of the technologies referenced above, refer tothe following brief tutorial: http://www.w3schools.com/soap/default.aspWeb services are for only one message and a single response to that message. To get a more in-depthunderstanding of the technologies referenced above, refer to the following brief ult.aspIRIS will make available to providers the CDC Web Services Description Language (WSDL). The WSDL willcontain information describing the publicly accessible ports that will be used by IRIS to exchange HL7messages. Providers will use this information to establish communication with IRIS and exchange HL7messages.Unbundled (Username token) Providers will need to create their own WS Client. Components that IRIS willprovide include:WSDLUsername/passwordSigned SSLPHINMS1.2.3.4.Obtain or develop, install and configure a client interface capable of transmitting an HL7 formattedMessage file via the Electronic Business using eXtensible Markup Language (ebXML) infrastructure tosecurely transmit public health information over the Internet to the Public Health InformationNetwork Messaging System (PHINMS) Message Receiver.The CDC provides, free of charge, their PHINMS client Message Sender for communication with theirPHINMS Message Receiver. Alternatively, the provider may choose to develop their own ebXMLMessage Sender to communicate with the PHINMS Message Receiver.The provider organization will submit a text file containing HL7 2.4 formatted VXQ V01 and VXU V04Messages (up to 100 messages are accepted) to be delivered via their ebXML-based client MessageSender to the IRIS PHINMS Message Receiver. IRIS will process the Messages and send back via thePHINMS Message Receiver a file of HL7 2.4 formatted Response Messages, one per associated query orvaccination update request.It is the responsibility of the provider organization to obtain or develop, install and configure anebXML client Message Sender for sending the HL7 2.4 formatted Message Requests and receiving theresulting HL7 2.4 formatted Message Response file generated by IRIS.The provider organization will need to obtain from IRIS a CPA (Collaboration Protocol Agreement) foraccess to the IRIS real time system. This is a file that contains information that will be used duringinstallation of the PHINMS Client software. The provider organization will need to obtain the IRIS SSLcertificate for secure access. See the PHINMS Installation Guide for detailed instructions. Please note:your certificate must be renewed annually. **IRIS PROVIDES NEITHER INSTALLATION,CONFIGURATION, NOR TECHNICAL SUPPORT FOR THE EBXML CLIENT MESSAGE SENDER.Full documentation and contact information for the PHINMS product may be found at the following link:http://www.cdc.gov/phin/Full documentation for the ebXML specification may be found at the following link:http://www.ebxml.org/specsPHINMS is ebXML version 2.0 compliant.4 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0Outline of real time message types and segmentsThe following section outlines the various message types that are transferred in real time files.Real time files that provider organizations send to IRIS:VXU - Unsolicited Vaccination UpdateMSHPID[PD1][{NK1}]RXA[RXR][{OBX}]Message HeaderPatient IdentificationPatient Additional DemographicNext of Kin / Associated PartiesPharmacy / Treatment Administration (at least ONE RXA is REQUIRED by IRIS)Pharmacy / Treatment Route (Only one RXR per RXA segment)Observation/ResultMSHQRDQRFMessage Header SegmentQuery Definition SegmentQuery Filter Segment (IRIS has made this segment REQUIRED)VXQ - Query for Vaccination RecordReal time (response) files that IRIS sends to provider organizations:VXR - Response TO Vaccination Query Returning the Vaccination OBX}]Message Header Segment (One per message)Message Acknowledgment Segment (One per message)Query Definition Segment (One per message)Query Filter Segment (One per message—required by IRIS)Patient Identification Segment (One per matching client)Additional DemographicsNext of Kin Segment (Optional, zero or more per matching client)Pharmacy AdministrationPharmacy RouteObservation/Result Contraindications or ReactionsObservation/Result Vaccines Due NextMSHMSAQRDQRFPID[{NK1}]Message Header Segment (One per message)Message Acknowledgment Segment (One per message)Query Definition Segment (One per message)Query Filter Segment (One per message—required by IRIS)Patient Identification Segment (One per matching client)Next of Kin Segment (Optional, zero or more per matching client)MSHMSA[ERR]Message Header SegmentMessage Acknowledgment SegmentErrorMSHMSA[ERR][QAK]Message Header SegmentMessage Acknowledgment SegmentErrorQuery Acknowledgment SegmentVXX - Response TO Vaccination Query (Returning Multiple PID Matches)ACK - General AcknowledgmentQCK - Query General Acknowledgment5 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0Details of real time message types and segmentsThe message segments below are needed to construct message types that are used by IRIS. Each segment isgiven a brief description excerpted from the HL7 standard. The tables define the fields that make up eachsegment.This Real time Transfer Specification only provides details regarding the messages and segments that arespecific to real time messages. Messages and segments that are common between real time HL7messaging and batch HL7 messaging are detailed in the IRIS - HL7 General Transfer Specification.Since IRIS does not use all the fields that HL7 defines, there can be gaps in the ordinal sequence of fields.Following HL7 rules, the gaps do not diminish the number of field separators within the segment. Forexample, if the second and third fields in a segment are not present, their field separators remain in order toindicate that the next field present is the fourth: field1 field4.Batch Message Headers (i.e. FHS, BHS) and footers (i.e. FTS, BTS) are NOT required for Real time processing.MSH – Message Header SegmentFor VXU and VXQ message types, the MSH segment must be constructed according to HL7 formatspecifications (refer to the HL7 2.4 - General Transfer Specification). For Real time processing, IRIS limits thenumber of MSH segments that can be processed in a single file. Files containing more than 100 MSHsegments will be rejected and an ACK message will be generated, informing the provider that 100 is themaximum number of MSH segments that IRIS accepts for Real time processing. However when using WebServices as a transport, IRIS only accepts one MSH record at a time; multiple MSH segments will causemessages to be rejected.VXU – Unsolicited Vaccination Record UpdateThe VXU message is used for sending client demographic and immunization specific data. This message typecan be sent via real time processing. VXU segments should be constructed according to the HL7 formatspecifications (refer to the HL7 2.4 - General Transfer Specification). A VXU message must be received in theHL7 2.4 format; IRIS does not support prior HL7 versions for Real time processing. IRIS validates the versionby reading the MSH-12 field. A VXU message must contain 2.4 in MSH-12.Immunization deletions can be submitted for both batch HL7 2.4 and Real time submissions. To indicate adeletion, the RXA-21 field must be populated with a value of “D”. Below is an example of a RXA deletionsegment. If the number of deletions received through batch exceeds 5 percent of the total number ofimmunizations or more than 50 immunizations are marked for deletion, IRIS will reject the file.RXA 0 999 19860715 19860715 90718 Td CPT 0 05 208 D VXQ – Query for Vaccination RecordWhen a health care provider (participating in an immunization registry) needs to obtain a complete patientvaccination record, a VXQ (query) is sent to IRIS for the definitive (last updated) immunization record. Thethree segments that make up a VXQ message are the MSH (message header), QRD (query definition) and QRF(query filter). For a VXQ message, the MSH-09 field must contain VXQ V01 and the segments must be in thefollowing sequence order:6 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0MSH \& QUERYINGORG QUERYINGORG IRIS IRIS 200212091511 VXQ V01 0000001 P 2.4 ERQRD 19970522 R I 000000001 25 RD 01 KENNEDY JOHN FITZGERALD JR VXI VACCINEINFORMATION HL700048 IRIS QRF IRIS 256946789 19900607 MA MA99999999 88888888 KENNEDY JACQUELINE LEE BOUVIER 898666725 KENNEDY JOHN FITZGERALD 822546618 The QRD and QRF segments are outlined in detail below.QRD – Query Definition SegmentUsed to define a 600910107YYYY012600480108ELEMENT NAMEQuery date/timeQuery Format CodeQuery PriorityQuery IDDeferred response typeDeferred response date/timeQuantity limited requestWho subject filterWhat subject filterWhat department data codeWhat data code value qualifierQuery results levelField Notes:QRD-1Date the query was generated by the application program. IRIS requires this field and verifiesthat a valid date is received. The minimum format of YYYYMMDD is required. A null/invalid valueresults in message rejection.QRD-2Query/response format code. IRIS requires this field and only accepts a value of “R”. Anull/invalid value results in message rejection.QRD-3Time frame in which the response is expected. IRIS requires this field and only accepts a value of“I”. A null/invalid value results in message rejection.QRD-4Unique identifier for the query assigned by the querying application. IRIS requires this field andnull/invalid values result in message rejection. This field is returned intact by IRIS in a response(VXR or VXX).QRD-5Used to indicate a deferred response. This is an optional field. IRIS does not support a deferredresponse.QRD-6Used to indicate the date/time of the deferred response. This is an optional field. IRIS does notsupport a deferred response.Maximum length of the response that can be accepted by the requesting system. The 1stQRD-7component is a numerical value, and the 2nd component accepts only the value “RD” (i.e. 5 RD ).A null/invalid value in either sub-component results in message rejection. IRIS will interpret theunits as the maximum number of client matching records to be returned via a VXX responsemessage.*Note: IRIS will return a maximum of 10 records per query message submitted. The value 0(zero) or any number 10 or greater will result in the maximum of 10 matches returned by IRIS.QRD-8Identifies the subject of the query or whom the inquiry is about. The 2nd component (last name)is required by IRIS. If the first or last name OR both names are missing (regardless if there arerepeating full names after the first) it results in message rejection. IRIS supports repetition of thisfield.QRD-9Describes the kind of information required to satisfy the request. IRIS requires this field and a7 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0QRD-10QRD-11QRD-12Example:value of “VXI” must populate the 1st component. IRIS supports repetition of this field. Null/invalidvalues result in message rejection if the field does not repeat. f the field repeats there must be atleast one value of “VXI” to be valid.Identifies the “what” department data code. IRIS requires this field and supports repetition of it.Null/invalid values will result in message rejection.Further refines the inquiry by data code qualifiers by providing a window or range. This is anoptional and repeatable field.Used to control level of detail in results. This field is optional and will be populated by IRIS withthe total count of PID matches found in IRIS when Query results in a VXX Response Message.QRD 19970522 R I 000000001 25 RD 01 KENNEDY JOHN FITZGERALD JR VXI VACCINEINFORMATION HL700048 IRIS 20QRF – Query Filter Segment – (REQUIRED by IRIS)Used with the QRD segment to further refine the content of a EMENT NAMEWhere subject filterWhen data start date/timeWhen data end date/timeWhat user qualifierOther query subject filterWhich data/time qualifierWhich date/time status qualifierDate/time selection qualifierWhen quantity/timing qualifierField Notes:QRF-1Identifies the department, system or subsystem to which the query pertains. IRIS requires this field. Anull/invalid value results in message rejection.QRF-2Data representing dates and times (registries do not value this component). This is an optional field.QRF-3Data representing dates and times (registries do not value this component). This is an optional field.QRF-4An Identifier to further define characteristics of the data of interest. This is an optional field.This field is used by registries to transmit up to ten separate search “keys”. IRIS requires this field and doesQRF-5NOT support repetition. The 2nd component (patient birth date) is required by IRIS. A null/invalid formatresults in message rejection. Format is YYYYMMDD.The “keys” within QRF-5 are ordered and separated by the repeat delimiter “ ”. If a “key” has no value, it isleft empty with the repeat delimiter holding its place. Order of data “keys” is as follows: patient Social Security Number patient birth date patient birth state patient birth registrationnumber patient Medicaid number mother's name last first middle mother's maiden name mother'sSocial Security Number father's name father's Social Security Number .Example:QRF IRIS 234567890 19900607 OR OR9999 MA8888 SMITH JANE LEE DOE 234567891 SMITH JOHN JO 234567892 8 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0VXR – Response TO Vaccination Query (Returning the Vaccination Record)When a patient has been uniquely identified (there is only one “match” to the query), the response to thequery is a VXR V03 message that is generated and sent back to the querying organization.IRIS will only return vaccines the patient is recommended to receive while evaluating the vaccine for agerestrictions (minimum age and interval), contraindications and other such rules. IRIS will evaluate vaccinesaccording to CDC ACIP schedule.VXR segment detailSeveral segments make up the VXR message type. The following segments have been outlined previously inthis document and will follow the same formatting for the VXR message type.MSH, MSA, QRD, QRF, PID, PD1, NK1, RXA, RXR, OBX (Observation/Result Contraindications or Reactions)In addition to supplying the querying organization with client specific demographic and immunization data(contained in the above segments), the VXR message also specifies “Observation/Result Vaccines Due Next”information. This information is supplied by generating three OBX segments per 1 vaccine recommendation.The set ID (OBX-01) for each OBX triplet will be the sequential set number uniquely identifying the OBX setfor an individual recommended vaccine. IRIS will report the Vaccination Schedule in the OBX segmentsthrough the specification of the LOINC code 30979-9 (Vaccines Due Next) and its sub-components in OBX-03.IRIS requires specification of OBX-05 when OBX-03 is specified and valid. Further, IRIS has superimposed aCE (Coded Element) data type on the OBX-05 field. The corresponding observation values will be specified inOBX-05. Combinations are as 5OBX-05HL70292 (Codes for vaccines administered CVX)Date Vaccine Due (IRIS provides date recommended)Earliest date to give (IRIS provides)Below you’ll find an example of what a recommendation might look like in a VXR message response (seebolded OBX segments below).MSH \& IRIS QUERYINGORG 20040101101 VXR V04 001 P 2.4 ERMSA AA 001 QRD 20040120 R I 001 1 RD 01 LAST NAME FIRST MIDDLE JR VXI VACCINE INFORMATION HL700048 IRIS 1 QRF IRIS 19900607 WI STATEBIR# MA# KENNEDY JACQUELINE LEE BOUVIER 898666725 KENNEDY JOHN FITZGERALD 822546618 587421369 19630119 MN MN99999999 88888888 DOE JANE ROSE SMITH 999999999 SMITH JOHN I 999999999 PID 1912484 123 PI LAST NAME FIRST MIDDLE JR 19900607 M PD1 01 Y A NK1 1 Hamus Eugene J Sr SEL SELF HL70063 12017 N ROCK INNRD AUBURNDALE WI 54412 USA (715)384-8649 RXA 0 999 20021001 20021001 90721 Diphtheria, Tetanus, Acellular Pertussis HIB CPT 0 Health Assessment& Promotion (HAP) Y HL70227 200210141430RXR IM LA OBX 1 CE 30979-9 Vaccine due next LN 1 20 DTAP CVX OBX 1 TS 30979-9&30980-7 Date vaccine due LN 1 20040130 OBX 1 NM 30979-9&30981-5 Earliest date to give LN 1 20040111 9 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0VXX – Response TO Vaccination Query (Returning Multiple PID Matches)When a health care provider participating in IRIS needs to obtain a complete patient vaccination record, aquery (VXQ message) is sent to IRIS for the definitive (last updated) immunization record. When a queryresults in multiple patient matches, the VXX message response is generated. The VXX contains multipleclients and their demographic information but does not contain their vaccination information. The number ofmatches that IRIS generates will depend on what is specified in the first component of the incoming VXQ(QRD-07 Quantity Limited request field). IRIS will interpret the quantity specified in this field as themaximum number of client matches that the requester desires.For example:If the query results in 100 matches and the original quantity specified in QRD-7 was 10, then IRIS generates10 PID (and if applicable, associated NK1) segments in the VXX response message.The following scenarios outline when a VXX message will be sent back when multiple matches are found, butsome of the matches have been locked.Scenario 1:The following paragraph holds true, assuming that the VXQ has 0 in QRD-7 (meaning that the providerorganization wants the maximum number of clients sent back).If IRIS matches 10 clients and 8 of those clients have locked records, then only 2 clients will be sent back inthe VXX message; the remaining 8 clients (having locked records) will not be sent back. The QRD-12 field (inthe VXX) will reflect the total number of matches found in IRIS (10 in our example) and the queryingorganization will need to assume that the 8 clients that were not returned had locked records.Example:VXQMSH \& IRIS QUERYINGORG 20040101101 VXQ V01 001 P 2.4 ERQRD 20040120 R I 01 0 RD 01 SALAMI STUART S VXI VACCINEINFORMATION HL700048 IRIS 0 QRF IRIS 19900607 VXXMSH \& IRIS QUERYINGORG 20040101101 VXX V02 001 P 2.4 ERMSA AA 001 0 0 Message Accepted HL70357 QRD 20040120 R I 01 0 RD 01 SALAMI STUART S VXI VACCINEINFORMATION HL700048 IRIS 10 QRF IRIS 19900607 PID 123 SR PI SALAMI BRAD S 19900607 M PID 456 SR PI SALAMI CHARLES 19900706 M NK1 1 SALAMI CHARLES SEL SELF HL70063 123 STREETADDRESS CITY WI 55555 USA (608)555-6666 Scenario 2:If IRIS matches 2 clients and both have locked records, then a QCK is generated. The QCK message will becomprised of the MSH, MSA and QAK segments. The MSA-01 field will have a value of “AR” (ApplicationReject). The MSA-3 field will display a message similar to “Potential match found. Record is locked; pleasecontact IRIS Help Desk for more information.” MSA-6 text will display, "Record not released".10 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0Example:VXQMSH \& IRIS QUERYINGORG 20040101101 VXQ V01 007 P 2.4 ERQRD 20040120 R I 01 0 RD 01 TEST INDICATOR NO VXI VACCINEINFORMATION HL700048 IRIS QRF IRIS 19760707 QCKMSH \& IRIS QUERYINGORG 20040101101 VXX V02 007 P 2.4 ERMSA AR 007 Potential match found. Record is locked; please contact IRIS Help Desk for moreinformation. 500 Record Not Released HL70357 QAK 01 NF ACK – Acknowledgment Messages (with Errors)ACK messages are generated for message rejections and for informational error messages. Three conditionsthat result in message rejection are:1. Sequencing (i.e., a PID segment must follow an MSH segment).2. Segment required fields contain no data.3. Segment required fields contain invalid data.An ACK is also generated when an informational error message has occurred, but it has not resulted inmessage rejection (i.e., NK1 segment contains no last name). In this case, the segment is ignored but theremainder of the message is processed. An ACK message is generated with a message informing the sender ofthe problem. The error message in the text does NOT include “Message Rejected”. The ACK contains the MSH,MSA and ERR segments.The MSH segment is generated according to normal HL7 processing guidelines. The MSA and ERR segmentsare detailed below:MSA – Message Acknowledgment OBORP/#TBL#00080102ELEMENT NAMEAcknowledgment codeMessage control IDText messageExpected sequence numberDelayed acknowledgment typeError conditionField Notes:The acknowledgment code indicates whether the message was accepted, rejected, error, etc.ThisMSA-1is a required field. IRIS generates an “AE” for messages resulting in informational or rejectionerrors. An “AA” is generated for a simple acknowledgment acceptance.The message control ID is the unique ID that is sent by the sending system. This is a requiredMSA-2field. It allows the sending system to associate each message with a response. In a response, thiswill be the same as the control ID that was sent in MSH-10 by the sending system.MSA-3This optional field further describes an error condition. When a message has been rejected, IRISgenerates “Message Rejection” as the first portion of the text describing the error message.Informational messages will not contain “Message Rejection”.MSA-4This optional numeric field is used in the sequence number protocol. IRIS does not generate thisfield.11 of 14

IRIS HL7 2.4 Real-time Transfer Specification Version 1.0MSA-5MSA-6This optional numeric field is used in the sequence number protocol. IRIS does not generate thisfield.Error Condition. IRIS does not generate this field.ERR – Error SegmentThe Error segment (ERR) is used to add error comments to acknowledgment messages. If the message wasrejected for functional reasons, this segment will locate the error and describe it using locally establishedcodes. Field components include: segment ID (ST) sequence (NM) field position (NM) code identifying error (CE) SEQ1Example:LEN80DTCMR/OR

Jan 07, 2013 · The underlying web service operation will be defined to be generic, and can exchange HL7 2.4 Messages and their appropriate Message Responses. The HL7 2.4 vaccination query (VXQ V01) or HL7 2.4 Unsolicited Vaccination Update (VXU V04) transactions and their Response Messages will be utilized under the same web service interface.

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