Introducing The Most Advanced Systems In Hemostasis Testing.
1tIntroducingThe most advanced systemsin Hemostasis testing.
A breakthrough in Hemostasis testing.New ACL TOP Family 50 SeriesOffering the most advanced automation and qualitymanagement from routine to specialty assays.Standardized across all ACL TOP systems—for superiorperformance across your entire testing process Same quality results Same comprehensive reagent portfolio Same powerful and intuitive software Same features and usabilityAnd now: Same assay-specific pre-analytical sample checks Same advanced lab accreditation support Same advanced quality management2tThe new ACL TOP Family 50 Series is designedto minimize errors and enhance quality.
Completely standardized for advanced automation and qualityIdeal for medium- to high-volume labs, including integrated lab automation systems—routineor specialty testing.For high-volume labsACL TOP 750Runs more tests in less time—user-friendly andhigh-throughput for routine analysis in laboratorieswith the heaviest workloads.ACL TOP 750 CTSClosed-Tube Sampling adds safety in routine, high-volumeand specialty labs.ACL TOP 750 LASConnects to laboratory automation tracks for maximumflexibility and efficiency.ACL TOP 750ACL TOP 750 CTSup to 360up to 270Samples onboard120120Reagents onboard6060Throughput (PT/hr)ACL TOP 550 CTSFor highly automated testing in routine,medium- to high-volume and specialty labs.Throughput (PT/hr)For medium-volume labsup to 240Samples onboard80Reagents onboard40ACL TOP 350 CTSThe most compact ACL TOP Family 50 Series system forroutine or specialty assays in medium-volume labs. Perfectcompanion to ACL TOP 750 CTS and 550 CTS systems.Throughput (PT/hr)up to 110Samples onboard40Reagents onboard263tFor medium- to high-volume labs
The ACL TOP FamilyAnalyzer automation Barcoded reagentsContinuous onboard reagent-stability monitoringAutomatic QC frequency executionRerun and reflex testing capabilitiesFully automated reporting of factor assays with parallelismAuto-verification and uploading of resultsClosed-Tube Sampling via cap-piercing (CTS models only)Continuous operation Continual loading and unloading of samples and reagents via racks with no system interruption Uninterrupted cuvette loading and waste disposalSimple maintenance Daily maintenance, ordered by user and performed by system, in 5 minutes “Maintenance overdue” notifications to alert user Remote instrument diagnostics and troubleshooting via web in real time* (optional)Laboratory automation Follows CLSI Guidelines (AUTO 1–5) for true “Point-of-Reference” sampling Open system compatible with most laboratory automation track systems Eliminates need for costly and slow robotic interfaceFast turnaround Up to 360 PT/hr PT results from standby in approximately 3 minutes Samples loaded on any rack, in any position, at any time, including STAT* Not available in all countries.Onboard barcode reader allows real-timereagent management.t4Closed-Tube Sampling enhances safetyin the testing process.
The ACL TOP Family 50 SeriesAutomated pre-analytical sample integrity checks Detects interference from Hemolysis, Bilirubin or Lipemia- Values exceeding assay-specific thresholds are flagged- Pre-set to validated thresholds with optional customization Detects tube-fill height issues Flags abnormal sample aspiration, prompting user to check for clotsAdvanced quality and accreditation support tools Most comprehensive set of audit-trail tools availableTime, date and operator stamps for all analyzer functions and activityMaintenance, QC and calibration logs, and temperature reportComprehensive and secure one-click audit reportsEnhanced system securitySecond-level password and electronic signatureAutomatic system log-offSystem-access restriction with user-specific log-in and passwordAutomatic password expirationComprehensive 21 CFR Part 11 support toolsOptional user-access restriction to patient-demographic information5t
Comprehensive assay menu fordisease state managementHemosIL assaysACL TOP Family 50 Series systems are optimized to operate with a comprehensive panel of HemosILassays. Together, they are a complete disease-state management solution. Innovative HemosIL assays,routine to specialty, help guide pathways for better patient care that can reduce costs associated withhospital length-of-stay and therapeutic management.True standardization throughout the lab for routine and specialty assays on all ACL TOP systemsGeneral Screening andAnticoagulant Monitoring/TestingRecombiPlasTin 2GPT-FIB HS PlusSynthASilAPTT-SPFibrinogen-CQ.F.A. ThrombinLiquid Anti-XaDirect Thrombin Inhibitor*D-DimerD-Dimer HS 500D-Dimer HSD-Dimer F4-H)*Antiphospholipid SyndromeSilica Clotting TimedRVVT Screen/ConfirmCoagulation FactorsIntrinsic FactorsExtrinsic FactorsFXIII AntigenThrombophiliaAntithrombinProtein C (Chromogenic)Protein C (Clotting)Free Protein S (Antigenic)Free Protein S (Clotting)FV Leiden (APC-R V)HomocysteineThromboPath*von Willebrand DiseaseVWF:RCo*VWF ActivityVWF:AgFVIIIFibrinolysisPlasminogenPlasmin Inhibitor* Not FDA cleared. Not saleable in the U.S.IIncreased efficiencies with HemosIL liquid,ready-to-use assays The great majority of Hemostasis tests performedin laboratories today are comprised of PT and APTT;therefore, their efficient use is essential. HemosIL high-sensitivity, liquid, ready-to-useassays are available for PT, APTT, D-Dimer,Anti-Xa and more. These assays deliver efficiency by:- Eliminating reconstitution errors for moreaccurate results- Eliminating extra pipetting steps forincreased efficiency- Reducing labor utilization overallLiquid, ready-to-use format.Significant Reduction in Hands-onTech Time for Vial Reconstitution*Competitor solutionHemosIL solutionReduced by – 65%*** Data on file, IL.** Assumes high-volume, routine testing with PT, APTT,D-Dimer and Fibrinogen assays.t6
A new breakthrough in Hemostasis testingACL TOP Family 50 Series systems are the first in Hemostasistesting to automate and integrate: Pre-analytical sample integrity checks Advanced quality management Lab accreditation tools7tACL TOP Family 50 Series. Advanced automation and qualityfor lab efficiency and better patient care.
ACL TOP Family 50 Series standardizes the Hemostasis testing process—forflexibility, efficiency and enhanced patient careTechnical SpecificationsTest menuClotting, chromogenic and immunological assaysSystem configurationsACLACLACLACLACLTOPTOPTOPTOPTOP750750 CTS750 LAS550 CTS350 CTSOpen-Tube SamplingClosed-Tube Sampling (cap-piercing)Laboratory Automation System compatibility (offboard sampling)Midsize with Closed-Tube SamplingCompact size with Closed-Tube SamplingSamples onboardACLACLACLACLTOPTOPTOPTOP750, 750 CTS750 LAS550 CTS350 CTS120Continuous from LAS track or 90 front-loaded8040Pre-analytical samplechecksAll ACL TOP Family50 Series systemsReagents onboardACL TOP 750, 750 CTS, 750 LAS 60ACL TOP 550 CTS40ACL TOP 350 CTS26Patient samples resultsdatabase20,000 samples (configurable)ACL TOP 750PT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . up to 360 tests/hr (360 samples/hr)APTT . . . . . . . . . . . . . . . . . . . . . . . up to 320 tests/hr (320 samples/hr)PT and APTT. . . . . . . . . . up to 330 tests/hr (165 samples/hr)ACL TOP 750 CTSPT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . up to 270 tests/hr (270 samples/hr)APTT . . . . . . . . . . . . . . . . . . . . . . . up to 270 tests/hr (270 samples/hr)PT and APTT. . . . . . . . . . up to 260 tests/hr (130 samples/hr)ACL TOP 750 LASThroughput from the LAS track is dependent upon factorssuch as LAS track configuration and settingsACL TOP 550 CTSPT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . up to 240 tests/hr (240 samples/hr)APTT . . . . . . . . . . . . . . . . . . . . . . . up to 180 tests/hr (180 samples/hr)PT and APTT. . . . . . . . . . up to 180 tests/hr (90 samples/hr)ACL TOP 350 CTSPT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . up to 110 tests/hr (110 samples/hr)APTT . . . . . . . . . . . . . . . . . . . . . . . up to 110 tests/hr (110 samples/hr)PT and APTT. . . . . . . . . . up to 110 tests/hr (55 samples/hr)Unit dimensions(w x d x h)ACLACLACLACLTOPTOPTOPTOP750, 750 CTS750 LAS550 CTS350 PTOP750750 CTS750 LAS550 CTS350 CTS16216618414791kgkgkgkgkgWerfenCorporate HeadquartersPlaza de Europa, 21–2308908 L’Hospitalet de LlobregatBarcelona, Spain 34-93-4010101werfen.comInstrumentationLaboratory Headquarters180 Hartwell RoadBedford, MA 01730 USA 1-781-861-0710www.ilww.com76 x 73 cm (59 x 30 x 29 in)87 x 162 cm (74 x 34 x 64 in) (includes integrated table and arm)82 x 73 cm (43 x 32 x 29 in)84 x 73 cm (32 x 33 x 29 in)(356 lbs)(367 lbs)(406 lbs)(324 lbs)(200 lbs)Worldwide LocationsUS, Canada, Latin Americaand South AmericaBrazilSão Paulo 55-11-41543337br.werfen.comCanadaRichmond Hill, ON 1-800-552-2025 x6115www.ilus.comColombiaBogotá 57(1)-616-7513MexicoCol. Granada 52-55-5262-1760ildiagnostics.comUruguayMontevideo 5982-481-81-33USABedford, MA , Sydney 61-02-9098-0200ChinaShanghai 86-21-66308671Beijing 86-10-59756055cn.werfen.comHong KongHong Kong 852-2792-7773cn.werfen.comIndiaNew Delhi 91-490-29-550in.ilwerfen.comJapanMinato-ku, Tokyo 81-3-5419-1301jp.werfen.comKoreaSeoul 82-2-5719246kr.werfen.comThailandBangkok 66-271-226-28/9Europe, Middle East, AfricaAustriaVienna 43-1-256-58-000at.werfen.comBeneluxBelgium 32-2-7252052The Netherlands 31-76-5480100benelux.werfen.comCzech RepublicPrague 420-246-090-931cz.werfen.comFranceLe Pré Saint Gervais 33-182-30-86-00fr.werfen.comGermanyMunich 49-89-909070de.werfen.comHungaryBudapest 36-1-882-73-10hu.werfen.comItalyMilan 39-02-25221it.werfen.comLithuaniaKaunas 370-37-313157lt.werfen.comPolandWarsaw 48-22-336-18-00SpainBarcelona 34-902-20-30-90es.werfen.comUKEngland 44-1925-810141uk.werfen.comFor all other countries visitinternational.werfen.comPortugalCarnaxide 351-214247312pt.werfen.comRussiaMoscow 7-499-124-45-59ru.ilwerfen.comCODEThe Instrumentation Laboratory logo, HemosIL, ACL, ACL AcuStar, ACL ELITE and ACL TOP are trademarks of Instrumentation Laboratory Company and/or oneof its subsidiaries or parent companies and may be registered in the United States Patent and Trademark Office and in other jurisdictions. All other productnames, company names, marks, logos and symbols are trademarks of their respective owners. 2015 Instrumentation Laboratory. All rights reserved.AFor more information, contact your local Werfen sales representative or distributor.tThroughputAssay-specific HIL sample check andsample aspiration clog check
Samples onboard ACL TOP 750, 750 CTS ACL TOP 750 LAS ACL TOP 550 CTS ACL TOP 350 CTS 120 Continuous from LAS track or 90 front-loaded 80 40 Pre-analytical sample checks All ACL TOP Family 50 Series systems Assay-specific HIL sample check and sample aspiration clog check Reagents onboard ACL TOP 750, 750 CTS,
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Le genou de Lucy. Odile Jacob. 1999. Coppens Y. Pré-textes. L’homme préhistorique en morceaux. Eds Odile Jacob. 2011. Costentin J., Delaveau P. Café, thé, chocolat, les bons effets sur le cerveau et pour le corps. Editions Odile Jacob. 2010. 3 Crawford M., Marsh D. The driving force : food in human evolution and the future.
