Stanford Medicine Symposium Novel Strategies For . - Stanford University

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StanfordMedicineSymposiumNovel Strategies For The Treatment Of Neurologic DisordersMay 9, 2020 8:30am - 4:30pmFour Seasons Hotel, Hong KongEvent SponsorsChi-Li Pao FoundationHong Kong Academy of Medicine

Program8:30 am Welcome and IntroductionsGary Steinberg, MD, PhD, Chair of Neurosurgery, Stanford University School of MedicineLloyd Minor, MD, Dean, Stanford University School of MedicineRaymond Pao, Founder, Chi-Li Pao FoundationGilberto Ka-Kit Leung, MBBS, PhD, Vice President (Education and Examinations), Hong Kong Academy of MedicineCerebrovascular Disease/Virtual RealityChairperson: Gregory Albers, MD, Stanford University School of Medicine9:00 amAcute Stroke InterventionGregory Albers, MD, Stanford University School of Medicine9:30 am10:00 amAneurysm Treatment; Virtual RealityGary Steinberg, MD, PhD, Stanford University School of MedicineCase Discussion with PanelGregory Albers, MD, Stanford University School of MedicineAnderson Chung-On Tsang, MBBS, The University of Hong KongGary Steinberg, MD, PhD, Stanford University School of Medicine10:30 am Tea breakBrain Tumors/Pediatric NeurosurgeryChairperson: Jenny Kan-Suen Pu, MBBS, The University of Hong Kong10:45 amTreatment of Primary Brain Tumors11:05 amCyberknife RadiosurgeryGordon Li, MD, Stanford University School of MedicineSteven Chang, MD, Stanford University School of Medicine11:25 amInnovative Surgical Management of Brain Tumors in ChildrenGerald Grant, MD, Stanford University School of Medicine11:45 amCase Discussion with PanelSteven Chang, MD, Stanford University School of MedicineDaniel Chua, MD, Hong Kong Sanatorium & HospitalGerald Grant, MD, Stanford University School of MedicineGordon Li, MD, Stanford University School of MedicineJenny Kan-Suen Pu, MBBS, The University of Hong Kong1

12:15 pm LunchMovement Disorders/Epilepsy/NeuromodulationChairperson: Gerald Grant, MD, Stanford University School of Medicine1:00 pmMedical Treatment of Movement DisordersKathleen Poston, MD, Stanford University School of Medicine1:20 pmNeuromodulation for Movement Disorders, Epilepsy, and Other Conditions1:40 pmNeurosurgery for Pediatric EpilepsyCasey Halpern, MD, Stanford University School of MedicineGerald Grant, MD, Stanford University School of Medicine2:00 pmCase Discussion with PanelGerald Grant, MD, Stanford University School of MedicineCasey Halpern, MD, Stanford University School of MedicineKathleen Poston, MD, Stanford University School of MedicineWa Hou Tai, MD, PhD, Macau Neuromedical Society2:30 pm Tea BreakSpine Surgery /Stem Cell TherapyChairperson: John Ratliff, MD, Stanford University School of Medicine2:45 pmSpine SurgeryJohn Ratliff, MD, Stanford University School of Medicine3:15 pmStem Cell Therapy for Stroke and Spinal Cord InjuryGary Steinberg, MD, PhD, Stanford University School of Medicine3:45 pmCase Discussion with PanelJohn Ratliff, MD, Stanford University School of MedicineGary Steinberg, MD, PhD, Stanford University School of Medicine4:15 pm Concluding Remarks2

Faculty(Listed in alphabetical order by last name.)Gregory W. Albers, MDThe Coyote Foundation Professor of Neurology and Professor, by courtesy, of NeurosurgeryStanford University School of MedicineProfessor Gregory W. Albers is the Director of the Stanford Stroke Center, a position he has held since co-foundingthe center in 1992.Professor Albers’ primary research focus is the diagnosis, management, and prevention of ischemic stroke. ProfessorAlbers and his team use advanced imaging technology to expand the treatment window for ischemic stroke. He hasbeen the principal investigator of all 3 NIH-funded DEFUSE studies, which clarified the evolution of brain ischemiaand led to extending the treatment window for stroke to 24 hours in 2018.Professor Albers was instrumental in the development of RAPID, a software platform that interprets brain scans andhelps clinicians decide on appropriate treatments for ischemic stroke. Professor Albers is the Chairman of the StrokeTreatment Academic Industry Roundtable (STAIR).A prolific and distinguished researcher, Professor Albers has authored more than 400 articles on topics related tocerebrovascular disease in peer-reviewed journals.Steven D. Chang, MDRobert C. and Jennette Powell Professor of Neurosurgery and the Neurosciences and, by courtesy,of Neurology and Otolaryngology - Head and Neck SurgeryStanford University School of MedicineAfter completing his Medical Degree and his Neurosurgery residency training at Stanford, Professor Chang joinedStanford’s Department of Neurosurgery where he is now Professor and Vice-Chairman of Strategic Developmentand Innovation. Professor Chang has a worldwide reputation as an expert in microsurgery and radiosurgery fortreatment of brain, spine, and skull base tumors; of arteriovenous malformations and cavernous malformations of thebrain and spine; and of intracranial aneurysms. His radiosurgery practice focuses on the use of the Cyberknife. He iscurrently Co-Director of both the Stanford Cyberknife Radiosurgery and Surgical Neuro-Oncology Programs.Professor Chang’s research interests include the genetic analysis of arteriovenous malformation patients and theclinical outcomes for radiosurgery of brain and spine tumors. He is the Director of the Stanford NeurogeneticsOncology Program and the Director of the Stanford Neuromolecular Innovations Program. He has authored or coauthored more than 300 peer-reviewed publications and book chapters.3

Daniel T.T. Chua, MD, FRCRAssociate Director, Comprehensive Oncology Center, Hong Kong Sanatorium & HospitalHonorary Associate Professor of Chinese University of Hong KongDr. Daniel Chua graduated from the Medical School of the Chinese University of Hong Kong in 1989. Shortly afterobtaining his specialist qualification in Clinical Oncology in 1994, Dr. Chua joined the Department of ClinicalOncology at the University of Hong Kong where he established the radiosurgery service and conducted most of hisresearch investigations.While an honorary faculty member of University of Hong Kong, Dr. Chua also maintains an active private practiceand continues with research. Dr. Chua’s primary interests are in the area of head and neck cancer, brain tumors,lung cancer, and precision radiotherapy. Dr. Chua has published over 200 peer-reviewed scientific papers and bookchapters.Gerald Grant, MD, FACSEndowed Professor in Pediatric Neurosurgery and Professor, by courtesy, of NeurologyStanford University School of MedicineProfessor Gerald Grant received his M.D. from Stanford University. Board-certified in neurosurgery and pediatricneurosurgery, Professor Grant specializes in the treatment of children and is Chief of Neurosurgery at Lucile PackardChildren’s Hospital. His clinical areas of interest include minimally invasive endoscopy, brain tumors, medicallyrefractory epilepsy, and concussion. As program director for the resident training program in neurosurgery atStanford, he is passionate about teaching and education. His translational research laboratory focuses on the bloodbrain barrier with the goal of improving drug delivery to improve the survival in children from brain tumors.Professor Grant recently served as Vice President of the Congress of Neurological Surgeons, and has served on theExecutive Committees of the AANS/CNS Joint Section of Pediatric Neurosurgery, and the American Society ofPediatric Neurosurgeons. He is currently Annual Meeting Chair for the AANS and is a national leader in developingquality metrics for pediatric neurosciences.Casey H. Halpern, MDAssistant Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences, andPsychiatry and Behavioral SciencesStanford University Medical CenterDr. Halpern received his medical degree from the University of Pennsylvania School of Medicine. He completedhis residency in Neurosurgery and a fellowship in Stereotactic and Functional Neurosurgery at the University ofPennsylvania. Dr. Halpern’s practice focuses on the surgical treatment of movement disorders, epilepsy, and severepsychiatric disease. He has particular interest in minimally invasive surgical approaches, as well as neurostimulationprocedures. Dr. Halpern’s research is involved in investigating the effects of deep brain stimulation in obesity usingmouse models of human behavior.4

Faculty ContinuedGordon Li, MDAssociate Professor of Neurosurgery and, by courtesy, of Neurology and of Head and Neck SurgeryStanford University School of MedicineAfter completing his medical degree at University of California Davis and his residency training at Stanford University,Dr Li joined the faculty in the Department of Neurosurgery at Stanford University School of Medicine where he isnow an Associate Professor. His active clinical practice is focused on the treatment of brain tumors, including the useof improved surgical techniques, immunotherapy, and novel applications of stereotactic radiosurgery. His research labstudies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant braintumors and translating that research into clinical trials.Kathleen Poston, MDAssociate Professor of Neurology & Neurological Sciences and, by courtesy of, NeurosurgeryStanford University School of MedicineDr. Kathleen Poston received her Bachelor’s of Science in Bioengineering at the University of Pennsylvania, herMaster’s Degree in Biomedical Engineering and her MD at Vanderbilt University. She completed her Neurologyresidency training at UCSF, completed a fellowship in clinical Movement Disorders at Columbia University and postdoctoral research training in Functional Neuroimaging at the Feinstein Institute.Dr. Poston’s research and clinical emphasis is to understand the motor and non-motor impairments that developin patients with alpha-synuclein pathology, such as Parkinson’s disease, Lewy body dementia, and Multiple SystemAtrophy. Her lab uses functional and structural imaging biomarkers, along with biological biomarkers, to understandthe underlying pathophysiology associated these symptoms. She holds joint appointments in Movement Disordersand Memory Disorders and is a founding member of the Stanford Alzheimer’s Disease Research Center. She leads theClinical Core for the Pacific Udall Center, which is an NIH-funded Parkinson’s disease Research Center of Excellence.Jenny Kan-Suen Pu, MBBSHonorary Clinical Associate ProfessorDepartment of Surgery, Division of NeurosurgeryThe University of Hong KongDr. Pu received a Bachelor of Science Degree from McGill University. She earned a MBBS and a Masters of Surgeryfrom the University of Hong Kong. She was awarded the Douglas Miller Medal from the Royal College of Surgeonsin Edinburgh, and now serves as a consultant in the division of neurosurgery at University of Hong Kong. She is theauthor of many articles published in peer reviewed journals and book chapters. Recognized for her expertise andleadership, she was elected and serves as President of the Hong Kong Society of Neuro-oncology.5

John Ratliff, MD, FACSProfessor of Neurosurgery and, by courtesy, of Orthopaedic SurgeryStanford University School of MedicineProfessor Ratliff’s clinical practice focuses upon complex spinal reconstructive surgery and adult deformity surgery.He is presently a professor of Neurosurgery and Orthopedic Surgery (by courtesy) at Stanford University, where heacts as Vice Chair for Operations and Development, Department Quality Officer, Associate Program Director, andCo-Director of Division of Spine and Peripheral Nerve Surgery. He is President-elect for the California Associationof Neurological Surgeons. Professor Ratliff’s research focuses upon use of “big data” in health care and uponimproving outcomes assessment in spine surgery patients. His research is supported by research grants from theAgency for Healthcare Research and Quality, the Orthopedic Research and Education Foundation, and from privatefoundations. He has published over 130 peer reviewed articles, recently completed his first textbook, and has beenfaculty for over 50 AANS and CNS courses.Gary K. Steinberg, MD, PhDBernard and Ronni Lacroute-William Randolph Hearst Professor in Neurosurgery and Neurosciences,and Professor, by courtesy, of NeurologyStanford University School of MedicineProfessor Steinberg specializes in cerebrovascular surgery. Chair of the Department of Neurosurgery since 1996, hehas expanded the department from 5 faculty to 63, and has trained more than 170 residents, fellows, graduate students.Professor Steinberg’s research focuses on developing innovative surgical, endovascular and radiosurgical treatmentsfor patients with intracranial aneurysms, vascular malformations and occlusive cerebrovascular disorders. He isalso studying the pathophysiology of stroke and methods to restore function after stroke. The California Institute ofRegenerative Medicine awarded him a 20 million grant to investigate neural stem cell transplant for chronic strokeand translate this into a clinical trial. He is also leading clinical trials of stem cell transplantation for spinal cordinjury, and traumatic brain injury.Professor Steinberg has received the Congress of Neurological Surgeons Charles Drake Lecturer, Stanford UniversityMedicine Alumni Lifetime Achievement Award, American Heart Association Stroke Progress and InnovationAward, Global Genes RARE Champion of Hope Honoree, Smithsonian American Ingenuity Award, and Society ofNeurological Surgeons H. Richard Winn, MD Prize.6

Faculty ContinuedWa Hou Tai, MD, PhDConsultant NeurosurgeonPresident, Macau Neuromedical SocietyDirector, Macau Children Assessment & Early Intervention CenterDr. Wa Hou Tai graduated from Sun Yat-sen University of Medical Sciences. He subsequently obtained a master’sdegree in neuropsychology and a doctorate in neurosurgery. He is currently actively engaged in clinical work andresearch in neurosurgery in Macau. His main interests are cerebrovascular diseases, epilepsy and congenital disorders.Dr Tai is also involved in healthcare administration and medical education, and is a board member of Macau MedicalAcademy, focusing on physician’s training.Anderson Chung-On Tsang, MBBS, FRCSClinical Assistant Professor, Division of Neurosurgery, Department of SurgeryThe University of Hong KongDr. Tsang obtained his medical degree with honors at the University of Hong Kong in 2010, after which he joined thefaculty as Clinical Assistant Professor in the Department of Surgery. He completed neurosurgery training in QueenMary Hospital, Hong Kong, specializing in endovascular neurosurgery and stroke treatment. He was awarded a Healthand Medical Research Fund Research Fellowship to pursue a Fellowship in Interventional Neuroradiology at TorontoWestern Hospital in 2018.Dr. Tsang’s research and publications are focused on acute stroke treatment, endovascular interventions foraneurysms, AVMs, and large vessel occlusion, and clinical neurosurgery. He is also committed to improve thesystems of care for hyperacute stroke in Hong Kong, and initiated cross-specialty projects with ambulance services,statisticians and computer scientists in pre-hospital stroke diagnosis. His ongoing research projects include clinicalstudies on large vessel occlusion thrombectomy in Asia, intracranial atherosclerosis, cerebral aneurysm, andintracranial hemorrhage.Special AcknowledgmentsThe Stanford Club of Hong Kong7

Notes

Notes

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Raymond Pao, Founder, Chi-Li Pao Foundation Gilberto Ka-Kit Leung, MBBS, PhD, Vice President (Education and Examinations), Hong Kong Academy of Medicine . Steven Chang, MD, Stanford University School of Medicine . author of many articles published in peer reviewed journals and book chapters. Recognized for her expertise and

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