CURRICULUM VITAE July 20, 2020 . - University Of Florida

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CURRICULUM VITAEJuly 20, 2020Peter P. SayeskiADDRESSDepartment of Physiology and Functional GenomicsUniversity of Florida College of Medicine1345 Center Drive, Room M552P.O. Box 100274Gainesville, FL 32610phone: 352-392-1816fax:352-846-0270e-mail: psayeski@ufl.eduURL: ATIONMay 1988March 1996B. A., Physiology-Anatomy, The University of California at Berkeley.Ph.D., Physiology and Biophysics, The University of Alabama at Birmingham.PROFESSIONAL EXPERIENCE1986-1988Undergraduate Student Researcher, Department of Biology/Reproductive Endocrinology, TheUniversity of California at Berkeley, Berkeley, California.1987-1988Undergraduate Student Researcher, Department of Anatomy/Neuroanatomy, The University ofCalifornia at Berkeley, Berkeley, California.1988-1990Research Technician, Department of Psychiatry and Behavioral Sciences, Stanford UniversityMedical Center, Stanford, California.1990-1996Graduate Student, Department of Physiology & Biophysics, The University of Alabama atBirmingham School of Medicine, Birmingham, Alabama.1996-2000Post Doctoral Fellow, Department of Pathology, Emory University School of Medicine, Atlanta,Georgia.2000-2006Assistant Professor, Department of Physiology and Functional Genomics, University of FloridaCollege of Medicine, Gainesville, Florida.2006-2012Associate Professor, Department of Physiology and Functional Genomics, University of FloridaCollege of Medicine, Gainesville, Florida.2012-present Professor, Department of Physiology and Functional Genomics, University of Florida College ofMedicine, Gainesville, Florida.ADMINISTRATIVE POSITIONS2008-present Program Director, University Scholars Program, University of Florida College of Medicine.2010-present Associate Chair, Department of Physiology and Functional Genomics, University of Florida Collegeof Medicine.2013-2017Associate Program Director, NIH T32 Multi-Disciplinary Training Program in Hypertension,University of Florida Health Science Center.2015-present Program Director, Graduate Physiology Certificates, University of Florida College of Medicine.2017-present Program Director, Medical Honors Program, University of Florida College of Medicine.

Peter P. Sayeski, Ph.D.ACADEMIC AFFILIATIONSMember, The University of Florida Hypertension CenterMember, The UF Health Cancer CenterINDUSTRY AFFILIATIONS2010-2012Scientific and Business Advisory Board Member, TeraDiscoveries, Inc.2013-2019Collaborator, Cellworks Group, Inc.2014-2017Founder and Chief Scientific Officer, MyeloJAK Biomarkers, LLCPROFESSIONAL SOCIETIESAmerican Heart AssociationAmerican Physiological SocietyFACULTY ADVISOR2013 - present TopSoccer, University of Florida2017 - present UF MEDLIFE, University of Florida2019 – present Footprints, University of Florida2019 – present Phi Delta Epsilon Medical Fraternity, University of FloridaPAST GRANT AWARDSEndocrinology, Metabolism, and Diabetes. National Institutes of Health/Research Training Grant, EmoryUniversity, Division of Endocrinology (T32-DK07298). 05/01/1996 - 04/30/1997. Total direct costs are 19,608.The Role of Src in Angiotensin II Signaling. National Institutes of Health/Individual National Research Service Award(NRSA). F32-HL09678. 05/01/1997 - 04/30/2000. Total direct costs are 93,948.Structure/Function Analysis of AT1/Jak2 Co-association. American Heart Association (National)/ScientistDevelopment Grant (#0130041N). 01/01/2001 - 12/31/2004. Total direct costs are 260,000.Characterization of Angiotensin II-mediated Stat1 Nuclear Accumulation. Howard Hughes Medical InstituteBiomedical Research Pilot Project Award (#53000287). 04/01/2001 - 12/31/2003. Total direct costs are 25,000.The Role of Jak2 in Cardiac Ischemia/Reperfusion. University of Florida Medical Guild Fellowship, Supervisor toEric M. Sandberg. 01/01/03 - 12/31/03. Total direct costs are 500.The Role of Jak2 in Angiotensin II Growth Responses. National Institutes of Health/Mentor Sponsored ResearchAward (K01-DK60471). 05/01/2001 - 04/30/2004. Total direct costs are 248,370.The Role of Jak2 in Cardiovascular Disease. American Heart Association, Florida/Puerto Rico Affiliate Pre DoctoralAward (#0315126B). Supervisor to Eric M. Sandberg. 07/01/03 - 06/30/05. Total direct costs are 38,000.Jak2 Phosphorylation Mapping and Protein Identification. American Heart Association, Florida/Puerto RicoAffiliate Post Doctoral Award (#0425378B). Supervisor to Dr. Xianyue Ma. 07/01/04 - 06/30/06. Totaldirect costs are 97,000.The Role of Jak2 in Mediating Angiotensin II-induced IP3 Receptor Degradation. American Heart Association,Florida/Puerto Rico Affiliate Pre Doctoral Award (#0515284B). Supervisor to Tiffany A. Wallace. 07/01/05- 06/30/06. Total direct costs are 21,000.Mechanisms of Jak2 Tyrosine Kinase Activation and Pharmacological Inhibition. American Heart Association,Florida/Puerto Rico Affiliate Grant in Aid (#0555359B). Principal Investigator. 07/01/05 - 06/30/07. Totaldirect costs are 120,000.The Role of c-Src/Yes/Fyn on ERK1/2 Cellular Function. American Heart Association, Florida/Puerto Rico AffiliatePre Doctoral Award (#0515138B). Supervisor to Michael D. Godeny. 07/01/05 - 06/30/07. Total directcosts are 42,000.2

Peter P. Sayeski, Ph.D.Pharmacological Inhibition of Jak2 Tyrosine Kinase. University of Florida Medical Guild Fellowship, Supervisor toJacqueline Sayyah. 07/01/06 - 06/30/07. Total direct costs are 500.Identification of Jak2 Tyrosine Kinase Inhibitors. University of Florida Division of Sponsored Research OpportunityFund. Principal Investigator. 07/01/07 - 12/31/08. Total direct costs are 68,000.Multi-Disciplinary Training Program in Hypertension. National Institutes of Health Training Grant (T32-HL83810).Supervisor to Jacqueline Sayyah (Dr. Chris Baylis, PI). 07/01/07 - 06/30/09. Total direct costs are 62,718.Prospective Identification of JAK2 Mutations that Render Resistance to the Novel JAK2 Inhibitor G6: Developmentof Next Generation Inhibitors. University of Florida / Moffitt Cancer Center Cooperative Funding Initiative(#0007-8481). Co-Principal Investigator. 12/10/08 - 12/09/09. Total direct costs are 100,000.Protein Kinases and Cell Growth. American Heart Association, Greater Southeast Affiliate Grant in Aid(#0855361E). Principal Investigator. 07/01/08 - 06/30/10. Total direct costs are 150,000.Vascular Smooth Muscle Cell Specific Deletion of Jak2 and the Pathogenesis of Cardiovascular Disease. Universityof Florida Medical Guild Fellowship, Supervisor to Annet Kirabo. 07/01/09 - 06/30/10. Total direct costsare 750.Methylarginines and Vascular Injury. National Institutes of Health/Independent Research Award (R01-HL81734).Co-Investigator (Dr. Arturo J. Cardounel, PI). 07/01/07 - 08/05/10.In Vivo Characterization of a Novel Jak2 Tyrosine Kinase Inhibitor for the Treatment of Jak2-mediated HumanPathologies. University of Florida Clinical and Translational Science Institute (#0008-5672). PrincipalInvestigator. 12/22/09 - 12/21/10. Total direct costs are 25,000.Vascular Smooth Muscle Cell Specific Deletion of Jak2 and the Pathogenesis of Cardiovascular Disease. AmericanHeart Association, Greater Southeast Affiliate Pre Doctoral Award (10PRE4310065), Supervisor to AnnetKirabo. 07/01/10 - 06/30/12. Total direct costs are 43,540.Improving the Metabolic Stability of the Jak2 Inhibitor G6. The State of Florida Biomedical ResearchPrograms/Bankhead Coley Technology Transfer Feasibility Award (2BF03). Principal Investigator.12/01/11 - 11/30/12. Total direct costs are 89,956.VSMC Jak2 and the Development of Chronic Kidney Disease in Ang II-dependent Hypertension. University of Florida/Division of Nephrology Cade Renal Pilot Project Award (#0009-2091). Co-Principal Investigator (Dr. ChrisBaylis). 01/01/11 - 12/31/12. Total direct costs are 80,000.The Role of Jak2 in Angiotensin II Signaling. National Institutes of Health/Independent Research Award (R01HL67277-09). Principal Investigator. 04/01/08 - 03/31/12. Total direct costs are 1,000,000. No costextension through 03/31/14.Vascular Ang II/Jak2 in Progression of Renal Disease. National Institutes of Health/Exploratory-DevelopmentalGrant Award (R21-DK92476-01). Co-Principal Investigator. 09/27/12 - 08/31/13. Total direct costs are 135,623.The Role of Vascular Smooth Muscle Cell Derived Jak2 Tyrosine Kinase in Angiotensin II-mediated pathogenesis.Greater Southeast Affiliate of the American Heart Association Grant-in-Aid Award (13GRNT16930005).Principal Investigator. 07/01/13 - 06/30/16. Total direct costs are 150,000.Pre-Clinical Analysis of Novel Therapeutic Strategies. Fee-for-Service Contract with CellWorks Group, Inc. Project#0011-1274. Principal Investigator. 10/01/13 - 03/31/17. Total Direct Costs are 48,735.Targeting Jak2 Tyrosine Kinase for the treatment of hypertension. Greater Southeast Affiliate of the AmericanHeart Association Grant-in-Aid Award (15GRNT25670060). Principal Investigator. 07/01/15 - 06/30/18.Total direct costs are 150,000.3

Peter P. Sayeski, Ph.D.STUDY SECTIONS AND COUNCILSMember, American Heart Association Southern and Ohio Valley Research Consortium, Committee 5A, CellularCardiovascular Physiology, Pharmacology, Molecular Genetics & Molecular Signaling, July 2001 - June2004.Ad Hoc Reviewer, University of Florida Shands Cancer Center, Pilot Project Research Committee Study Section,University of Florida College of Medicine, 2003.Ad Hoc Reviewer, Philip Morris External Research Program, 2004.Ad Hoc Reviewer, Minority Biomedical Research Support (MBRS) Program, Morehouse School of Medicine, 2005.Ad Hoc Reviewer, Office of Research and Graduate Programs, Beckman Young Investigator Award, University ofFlorida, 2006.Ad Hoc Reviewer, National Science Foundation, 2006.Ad Hoc Reviewer, University of Florida Shands Cancer Center, Young Investigator Award Study Section, Universityof Florida College of Medicine, 2006.Co-Chair, American Heart Association Southern and Ohio Valley Research Consortium, Committee 5A, CellularCardiovascular Physiology, Pharmacology, Molecular Genetics & Molecular Signaling, July 2006 - June2007.Ad Hoc Reviewer, Philip Morris External Research Program, 2007.Chair, American Heart Association Region II Basic Cell and Molecular Biology II Study Group, July 2007 - June 2009.Ad Hoc Reviewer, National Institutes of Health, Vascular Cell and Molecular Biology (VCMB) Study Section, 2009.Ad Hoc Reviewer, Basic Science Grant Review Subcommittee for the American Cancer Society Chris DiMarcoInstitutional Research Grant, The University of Florida Shands Cancer Center, 2010.Ad Hoc Reviewer, The Special Research Program of the Austrian Science Fund, 2011.Ad Hoc Reviewer, National Institutes of Health, Vascular Cell and Molecular Biology (VCMB) Study Section, 2011.Ad Hoc Reviewer, National Institutes of Health, Special Emphasis Panel for the NIH Director’s Early IndependenceAwards (DP5), 2011.Ad Hoc Reviewer, University of Florida Searle Scholars Grant Review Committee, 2011.Ad Hoc Reviewer, National Institutes of Health, P50 Pediatric Centers of Excellence in Nephrology (ZDK1 GRB-G)Study Section, 2012.Ad Hoc Reviewer, Basic Science Grant Review Subcommittee for the American Cancer Society Chris DiMarcoInstitutional Research Grant, The University of Florida Shands Cancer Center, 2012.Ad Hoc Reviewer, The Special Research Program of the Austrian Science Fund, 2012.Ad Hoc Reviewer, Physicians’ Services Incorporated (PSI) Foundation, Toronto, Ontario, Canada, 2013.Ad Hoc Reviewer, National Institutes of Health, Omnibus Special Emphasis Panel, Scientific Review Group 2014/01ZCA1 RPRB-0 (J1) S, 2013.Ad Hoc Reviewer, National Institutes of Health, Omnibus Special Emphasis Panel, Scientific Review Group 2014/10ZCA1 SRB-V (01) S, 2014.Ad Hoc Reviewer, Basic Science Grant Review Subcommittee for the American Cancer Society Chris DiMarcoInstitutional Research Grant, The UF Health Cancer Center, 2014.Ad Hoc Reviewer, National Institutes of Health, Omnibus Special Emphasis Panel, Scientific Review Group 2015/01ZCA1 SRB-V (J1) R, 2014.Ad Hoc Reviewer, National Institutes of Health, Omnibus Special Emphasis Panel, Scientific Review Group 2016/01ZCA1 SRB-V (J1) S, 2015.Ad Hoc Reviewer, Pharmacy Recurring Opportunity Seed Program for Education and Research (PROSPER),University of Florida College of Pharmacy, 2015.Ad Hoc Reviewer, National Institutes of Health, NCI Research Specialist Award (R50), Scientific Review Group2016/08 ZCA1 SRB-V (A1) S, 2016.Ad Hoc Reviewer, The Special Research Program of the Austrian Science Fund, 2016.4

Peter P. Sayeski, Ph.D.Ad Hoc Reviewer, Research Opportunity Seed Fund Review Committee, University of Florida Office of Research,2017.Ad Hoc Reviewer, The Special Research Program of the Austrian Science Fund, 2018.Ad Hoc Reviewer, The UF Health Cancer Center Pre-Doctoral Awards Program. University of Florida College ofMedicine, 2018.Ad Hoc Reviewer, UFII-CTSI Pilot Project Program, “Big Data in Health,” UF Health Science Center, 2019.Ad Hoc Reviewer, The UF Health Cancer Center Pre-Doctoral Awards Program. University of Florida College ofMedicine, 2019.Ad Hoc Reviewer, Collaborative Sciences Award Review Committee, the American Heart Association, 2019.REVIEWER AND EDITORIAL BOARDSEditorial Board Member:PeptidesStem Cell InvestigationAd Hoc Reviewer: Journal of Clinical Investigation, EMBO Journal, Journal of Biological Chemistry, Nature ChemicalBiology, Hypertension, AJP-Cell Physiology, AJP-Renal Physiology, American Journal of Pathology, PLOS ONE,Journal of Pathology, International Journal of Cancer, Journal of Cellular Physiology, Journal of MedicinalChemistry, ACS Medicinal Chemistry Letters, Current Medicinal Chemistry, Expert Opinion on Therapeutic Targets,Pharmaceuticals, BMC Structural Biology, Physiological Genomics, Cardiovascular Diabetology, LaboratoryInvestigation, Journal of Hematology and Oncology, and Regulatory Peptides.HONOR AWARDSVeterans of Foreign Wars Scholarship, The University of California at Berkeley, 1983-1987.Sophus C. Gothe Honor Award, Tau Kappa Epsilon Fraternity, The University of California at Berkeley, 1985.Top Teke Merit Award, Tau Kappa Epsilon Fraternity, Univ. of California at Berkeley, 1986.William C. Dement Research Award, Stanford University Medical Center, Stanford, CA, 1989.Dean’s Award, UAB Dean of Student Affairs, University of Alabama at Birmingham, 1994.Samuel B. Barker Research Award, Dept. of Medicine, Univ. of Alabama at Birmingham, 1995.Trainee Investigator Award, The Clinical Research Meetings, San Diego, CA, 1995.Second Place Award, Sigma Xi Research Competition, Univ. of Alabama at Birmingham, 1995.Dean’s Award, UAB Dean of the Graduate School, University of Alabama at Birmingham, 1995.National Graduate Achievement Award, The National Graduate Council, Wash. D.C., 1995.Nominee, Emory University School of Medicine Nominee for the Burroughs Wellcome Career Award in theBiomedical Sciences, 1999.Trainee Investigator Award, Keystone Symposia on the Molecular Biology of the Cardiovascular System, Snowbird,Utah, 2000.Honorary Fellow, Council for High Blood Pressure Research of the American Heart Association, 2001.Young Investigator Travel Award, Cardiovascular Section of the American Physiology Society, Experimental BiologyMeetings, New Orleans, Louisiana, 2002.Recognized as the top 5% of Outstanding Teachers within the College of Medicine, University of Florida, 2004.Exemplary Teacher Award, University of Florida College of Medicine, 2005.Exemplary Teacher Award, University of Florida College of Medicine, 2006.Exemplary Teacher Award, University of Florida College of Medicine, 2007.Doctoral Mentoring Award, University of Florida College of Medicine, 2008.Exemplary Teacher Award, University of Florida College of Medicine, 2008.Honorary Fellow, Cardiovascular Section of the American Physiological Society, 2010.Exemplary Teacher Award, University of Florida College of Medicine, 2010.Doctoral Mentoring Award, University of Florida College of Medicine, 2012.5

Peter P. Sayeski, Ph.D.Doctoral Dissertation Advisor/Mentoring Award, University of Florida Graduate School, 2012.Exemplary Teacher, Five Year Award, University of Florida College of Medicine, 2012.Commencement Speaker, Convocation of the Interdisciplinary Graduate Program (IDP) in Biomedical Sciences,University of Florida College of Medicine, 2013.Exemplary Teacher Award, University of Florida College of Medicine, 2013.Exemplary Teacher Award, University of Florida College of Medicine, 2014.Exemplary Teacher Award, University of Florida College of Medicine, 2015.Basic Science Teacher of the Year, University of Florida College of Medicine, 2015.Exemplary Teacher Award, University of Florida College of Medicine, 2017.Exemplary Teacher Award, University of Florida College of Medicine, 2018.Phase 1 Teacher of the Year, University of Florida College of Medicine, 2019.Exemplary Teacher Award, University of Florida College of Medicine, 2019.Commencement Marshall, University of Florida College of Medicine Class of 2020, Gainesville, FLHONOR AWARDS FOR TRAINEESEric Sandberg, Travel Award to attend the 14th Annual Meeting of European Society of Hypertension, Paris,France, 2004.Eric Sandberg, Medical Guild Research Award, University of Florida College of Medicine, 2004.Eric Sandberg, Named a Frederick Gardner Cottrell Postdoctoral Fellow at Emory University, 2004.Michael Godeny, Best Basic Science Poster Award, University of Florida College of Medicine Research Day, 2005.Michael Godeny, Medical Guild Research Award, University of Florida College of Medicine, 2006.Michael Godeny, Exemplary Teacher Award, University of Florida College of Medicine, 2006.Jacqueline Sayyah, University Women's Club Scholarship, University of Florida, 2006.Jacqueline Sayyah, University of Florida’s Graduate Student Nominee to attend the 2007 Nobel LaureatesMeeting, Lindau, Germany, 2007.Annet Kirabo, Selected to attend the American Physiological Society’s Critical First Skills Scientific Workshop,Orlando, FL, 2009.Kavitha Gnanasambandan, International Student Award, University of Florida, 2009.Annet Kirabo, Carolyn tum Suden/Francis A. Hellebrandt Professional Opportunity Award from the AmericanPhysiological Society, 2010.Sung Park, Travel Award to attend the 52nd Annual Meeting of the American Society of Hematology, Orlando, FL,2010.Kavitha Gnanasambandan, Travel Award from the American Society for Biochemistry and Molecular Biology toattend the Experimental Biology Meeting, Washington DC, 2011.Annet Kirabo, Minority Travel Award from the American Physiological Society/NIDDK to attend the ExperimentalBiology Meeting, Washington DC, 2011.Sung Park, Best in Research Award, University of Florida Hematological Malignancies Symposium, Gainesville, FL,2012.Sung Park, Physiological Genomics Research Award, Experimental Biology Meeting, San Diego, CA, 2014.TEACHING (Non Faculty Assignments) Teaching Assistant, Dental Physiology (PHY 701), Univ. of Alabama at Birmingham, 1991.Teaching Assistant, Graduate Biochemistry (CMB 701), Univ. of Alabama at Birmingham, 1991.Teaching Assistant, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1992.Laboratory Instructor, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1992.Lecturer, Physiology for Nurse Anesthetists (ANS 318), Univ. of Alabama at Birmingham, 1993.Laboratory Instructor, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1993.Teaching Assistant, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1993.6

Peter P. Sayeski, Ph.D.Laboratory Instructor, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1994.Teaching Assistant, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1994.Lecturer, Physiology for Biomedical Engineers (BME 510-710), University of Alabama at Birmingham, 1994.Laboratory Instructor, Medical Physiology (PHY 700), Univ. of Alabama at Birmingham, 1995.Lecturer, Physiology for Biomedi

CURRICULUM VITAE July 20, 2020 Peter P. Sayeski ADDRESS- Department of Physiology and Functional Genomics University of Florida College of Medicine 1345 Center Drive, Room M552 P.O. Box 100274 . Emory University School of Medicine, Atlanta, Georgia. 2000-2006 Assistant Professor, Department of Physiology and Functio

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