Radiation-Utilizing Technology Overview

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Radiation-UtilizingTechnology OverviewA survey of critical technologies utilizing radiationandHow YOU will understand their functions after 22.01MIT 22.01: Intro to Ionizing RadiationPage 1

Motivation for Today Answer two question in a few ways: How can radiation be used to our benefit? What is the physics behind how it is used?MIT 22.01: Intro to Ionizing RadiationPage 2

Types of Technology PowerMedical SpaceSemiconductors Product DevelopmentCourtesy of City Labs, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationCourtesy of Argonne National Laboratory on Flickr. License CC BY-NC-SA.Page 3

Nuclear Powerhttp://www.nucleartourist.com/type/pwr cycle.htm Overall reactor diagram Westinghouse. All rights reserved. This content is excluded from our CreativeCommons license. For more information, see http://ocw.mit.edu/help/faq-fair-use/.MIT 22.01: Intro to Ionizing RadiationPage 4

Nuclear Powerhttp://www.nucleartourist.com/type/pwr cycle.htm Pressurized Water Reactor (PWR) Asian Network for Scientific Information. All rights reserved.This content is excluded from our Creative Commons license.For more information, see http://ocw.mit.edu/help/faq-fair-use/.Source: Hussain, A., and C. Xinrong. "Core OptimizationSimulation for a Pressurized Water Reactor." InformationTechnology Journal 8, no. 2 (2009): MIT 22.01: Intro to Ionizing Radiation Westinghouse. All rights reserved. This content is excluded from our CreativeCommons license. For more information, see http://ocw.mit.edu/help/faq-fair-use/.Page 5

How a Reactor Core Works Fuel, fission, and energetics Control rods Coolant and moderation Reflection and shieldingMIT 22.01: Intro to Ionizing RadiationPage 6

A Neat Aside"Advanced Test Reactor" by Argonne National Laboratory CherenkovRadiation Beta particlestraveling fasterthan the speed oflight in waterCourtesy of Argonne National Laboratory on Flickr. License CC BY-NC-SA.MIT 22.01: Intro to Ionizing RadiationPage 7

Fusion Energyhttp://www.iter.org/ Fuse light nuclei (D D or D T) instead ITER Organization. All rights reserved. This content is excluded from our CreativeCommons license. For more information, see http://ocw.mit.edu/help/faq-fair-use/.MIT 22.01: Intro to Ionizing RadiationPage 8

Fusion Reactor u/mirai-en/2006/3 12.html Fuse light nuclei, breed fuel from 7Li Use Pb-17Li, enrich in 7Li21𝐷 31𝑇 42𝐻𝑒 10𝑛10𝑛 73𝐿𝑖 31𝑇 42𝐻𝑒 10𝑛10𝑛 63𝐿𝑖 31𝑇 42𝐻𝑒 Japan Atomic Energy Agency. All rights reserved. This content is excluded from our CreativeCommons license. For more information, see http://ocw.mit.edu/help/faq-fair-use/.MIT 22.01: Intro to Ionizing RadiationPage 9

Why Fission and Fusion Workhttps://en.wikipedia.org/wiki/Nuclear binding energyFission releases binding energyFusionreleasesbindingenergyCan’t gain energy fromfission or fusion!Public domain image.MIT 22.01: Intro to Ionizing RadiationPage 10

Medical Uses of Radiation Imaging X-ray therapy Proton therapy Brachytherapy RadiotracersMIT 22.01: Intro to Ionizing RadiationPage 11

Imaging Differential absorption (attenuation) of x-raysFirst x-ray taken by C. RoentgenMIT 22.01: Intro to Ionizing Radiation2010Courtesy of Porcaro Family on Flickr. License CC BY-NC-SA.Page 12

Imaging Differential absorption (attenuation) of x-rays2010Public domain, from U.S. NIST.Courtesy of Porcaro Family on Flickr. License CC BY-NC-SA.First x-ray taken by C. RoentgenMIT 22.01: Intro to Ionizing RadiationPage 13

X-Ray Therapy Hinges upon absorption of x-rays by tumorsCONVERGINGGAMMA RAYSSHIELDINGTARGETRADIOACTIVECOBALT SOURCESSPHERICAL HELMETFOR FURTHER BEAMNARROWINGImage by MIT OpenCourseWare.MIT 22.01: Intro to Ionizing RadiationPage 14

Proton Therapy Use an accelerator (cyclotron) to accelerate protons, firethem into the tumor! The New York Times. All rights reserved. This content isexcluded from our Creative Commons license. For moreinformation, see http://ocw.mit.edu/help/faq-fair-use/.Courtesy of Vietnam Open Educational Resources. License CC from-energy/389d856bMIT 22.01: Intro to Ionizing RadiationSee 08/the-power-of-proton-therapyPage 15

Why Protons vs. X-Rays? Highly controllable range vs. just attenuationRun SRIM live as demoMIT 22.01: Intro to Ionizing RadiationPage 16

Why Protons vs. X-Rays? Intensity Modulated Radiation Therapy (IMRT)A set of tungstenleaves control eachbeam's shapeProstate shapeBeam shapedynamically adjustedduring exposureto control intensityProstateTorsocross-section American Academy of Family Physicians. All rights reserved. Thiscontent is excluded from our Creative Commons license. For moreinformation, see /www.aafp.org/afp/2008/1201/p1254.htmlMIT 22.01: Intro to Ionizing RadiationImage by MIT OpenCourseWare.Page 17

Why Protons vs. X-Rays? Intensity Modulated Radiation Therapy (IMRT)Courtesy of Macmillan Publishers Ltd. License CC BY-NC-SA.Source: W. P. Levin et al. "Proton beam therapy." British J. Cancer, 93(8):849-854 (2005).W. P. Levin et al. "Proton beam therapy." British J.Cancer, 93(8):849-854 (2005).MIT 22.01: Intro to Ionizing RadiationPage 18

herapy Relies on simple radioactive decay Implanted directly into tumor Brachytherapy “seeds’Public domain photo.MIT 22.01: Intro to Ionizing RadiationIr-192 commonly usedShort or long range?Short or long half life?Biocompatibility?Courtesy of Korea Atomic Energy ResearchInstitute. Used with permission.Page 19

Radiotracers Typically 99Mo 99mTc, attached to otherchemicals for imaging proceduresDetected decayenergyCourtesy of Korea Atomic Energy Research Institute. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 20

tamibisSPECT.html Typically 99Mo 99mTc, attached to otherchemicals for imaging proceduresCourtesy of Bechara Y. Ghorayeb, MD. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 21

HUGE 99Mo Shortages!Nature 460, 312-313 (2009), doi:10.1038/460312aReprinted by permission of Macmillan Publishers Ltd.Source: Gould, Paula. "Medical isotope shortagereaches crisis level." Nature 460, 312-313 (2009).Soon, highly enriched targets will be illegal MIT 22.01: Intro to Ionizing RadiationPage 22

Space Applications Astronaut Shielding Radioisotope Thermoelectric Generators (RTGs) Nuclear RocketsMIT 22.01: Intro to Ionizing RadiationPage 23

Shielding Must know basic principles of shielding vs. Density fa beta gamma radiation penetration.svg EnergyCourtesy of Wikipedia User: Stannered. License CC BY.MIT 22.01: Intro to Ionizing RadiationPage 24

More Complex Shieldinghttp://www.nasa.gov/offices/oct/early stage innovation/niac/westover radiation protection.htmlPublic domain image.MIT 22.01: Intro to Ionizing RadiationPage 25

RTGs Long-lived, high power decay heat sourcesPublic domain ystem.nasa.gov/rps/docs/MMRTGfactsFeb 2010.pdfMIT 22.01: Intro to Ionizing RadiationPage 26

Nuclear orry-about-a-nuclear-future-in-space Thrust may be lower, but life is longer!Public domain MIT 22.01: Intro to Ionizing RadiationPage 27

Semiconductor Processinghttp://nrl.mit.edu/facilities/ntds VERY precise n-type doping of Si to PCourtesy of MIT Nuclear Reactor Laboratory. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 28

Accelerator Applicationssee animation at screens-are-made-2014-9 Making super thin, scratch-proof iPhone screensCourtesy of Neutron Therapeutics, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 29

Accelerator Applicationssee animation at screens-are-made-2014-9 Making super thin, scratch-proof iPhone screensCourtesy of Neutron Therapeutics, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 30

Accelerator Applicationssee animation at screens-are-made-2014-9 Making super thin, scratch-proof iPhone screensCourtesy of Neutron Therapeutics, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 31

Accelerator Applicationssee animation at screens-are-made-2014-9 Making super thin, scratch-proof iPhone screensCourtesy of Neutron Therapeutics, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 32

Other Productshttp://www.citylabs.net/ Betavoltaics – direct usage of beta particle charge Semiconductorband gap accelerates electronhole pairsCourtesy of City Labs, Inc. Used with permission.MIT 22.01: Intro to Ionizing RadiationPage 33

Detectors Various kinds for different usesBF3 neutron detector –Courtesy of ORAU Foundation. Used with ortional%20counters/nucchicago205bf3.htm STC RADEK Ltd. All rights reserved. Thiscontent is excluded from our Creative Commonslicense. For more information, ty Ge gamma spectrometer diometers-of-radiation/49/Courtesy of Robert Hart. Used with permission.Two ionization tubes used as a muon coincidencedetector - -9x9-pixel-hodoscopeMIT 22.01: Intro to Ionizing Radiation Libelium Comunicaciones Distribuidas S.L. All rightsreserved. This content is excluded from our CreativeCommons license. For more information, nt Geiger tube o-raspberry-pi-tutorial/Page 34

MIT OpenCourseWarehttp://ocw.mit.edu22.01 Introduction to Nuclear Engineering and Ionizing RadiationFall 2015For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.

Courtesy of Argonne National Laboratoryon Flickr. License CC BY-NC-SA. Nuclear Power Overall reactor diagram . MIT 22.01: Intro to Ionizing Radiation . . Intensity Modulated Radiation Therapy (IMRT) MIT 22.01: Intro to Ionizing Radiation . Page 18 . W. P. Levin et al. "Proton beam therapy." British J. Cancer

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