NMR SOLVENTS Deuterated Solvents For NMR
Cambridge Isotope Laboratories, Inc.www.isotope.comNMR SOLVENTSDeuterated Solventsfor NMR NMR Solvents NMR Reference Standards NMR Tubes
NMR .comTABLE OF CONTENTSContact Information.1Shipping Information.1Packaging Information.2NMR Solvents.3-16NMR Tubes.17NMR Reference Standards.15,16NMR Solvent Technical Tips.19NMR Solvents Data Chart.20, 21Chemical Shifts of Solvents.22tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comContact InformationContact CIL by Phone, Fax or E-mailThe CIL Customer Service Department is open Monday-Thursday 8:00 A.M. to 5:30 P.M.; Friday 8:00 A.M. to 5:00 P.M EST.PhoneFaxE-mail1-800-322-1174 (USA)1-978-749-2768cilsales@isotope.com (North America)1-800-643-7239 (Canada)intlsales@isotope.com (International)1-978-749-8000 (International)envsales@isotope.com (Environmental Products)1-800-322-1174 (Environmental)1-800-ISOTOPE ( US Regional Sales Manager)Contact Your Regional Sales ManagerPlease contact your local sales representative to request a quote or discuss long term blanket discount orders. Dialing1-800-ISOTOPE within the US will automatically put you in touch with your local Sales Manager. You may also visit ourWeb site at www.isotope.com for a list of Regional Sales Managers and the areas they service.Contact Your Customer Account CoordinatorIn order to provide our loyal customers with seamless customer service, each Regional Sales Manager has a dedicatedCustomer Account Coordinator assigned to their territory. Your Customer Account Coordinator is available to processyour orders and quote requests as well as to confirm the delivery status of your order. Please contact your local CustomerAccount Coordinator to request a quote or to place an order. For a listing of Domestic and International Customer AccountCoordinators and the areas they service, please visit our Web site at www.isotope.com.Contact Your International DistributorIn order to provide our international customers with the best service possible, CIL has an established network ofindependent international distributors. Most of our distributors have worked with CIL for more than ten years. To requesta quotation or place an order, please contact your local distributor noted on back cover. Our International CustomerService Department is also available to assist you.sHIPPING INFORMATIONShipments within the United States will be sent via UPS, Federal Express, or truck. Canadian shipments will besent via Federal Express or truck. International shipments of non-hazardous materials will be sent via Federal Express or best method. Hazardous materials will be shipped by air freight, surface vessel or Federal Express where applicable. CIL triesto be as cost effective as possible, but the carrier may place additional charges. Hazardous substances are identified with the appropriate UN number and transported in compliance with UNrecommendations. We will oblige your shipping instructions whenever it is feasible to do so. CIL reserves the right to change themethod of transportation if required to comply with transportation regulations. Such a change would not alteryour responsibility for payment of shipping charges. Additional shipping charges may apply.tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com2
Cambridge Isotope Laboratories, Inc.www.isotope.comNMR SolventsunitCatalog listings includeNew Indicator: NEWAlternative NameFormulaMolecular Weight *UnitDensityEnrichmentCompound NameDimethyl Sulfoxide-d6 (D,99.9%) (contains 0.05% v/v TMS) (DMSO)CD3SOCD3DLM-10tbCIL Catalog #CAS #[2206-27-1]10x0.6 mL10x0.75 mL10x1 g3x(10x1 g)5g10 g10x10 g3x(10x10 g)25 g50 gmw 84.17d 1.18Additional InformationUN#Hazard ClassStorage Information*** Molecular weight is based on 100% enrichmentShipping RestrictionsStructure** Stable if stored under normal conditions, unless other wise notedour labels includeCambridge IsotopeLaboratories, Inc. Product name and description50 Frontage RoadAndover, MA 01810 USA978-749-8000 Health and safety information Lot specific number Package size Pictograms for hazard recognition CAS numbersDIMETHYL SULFOXIDE-D610 X 0.75MILLILITERS(D, 99.9%)DLM-10-10X0.75CAS 2206-27-1LOT# 9C-999Irritant. Combustible. Hygroscopic. Maybe harmful if inhaled,swallowed, or absorbed through skin.Store at room temperature away from light and moisture. Storage information Packaging number Catalog numberFor research use only - not for diagnostic purposesTech Info:Each batch of CIL solvent isroutinely tested for chemical andisotopic purity after initialHazardous iconspurification, before packaging,and after losiveFlammableHarmful IrritantOxidizingToxicCompounds listed in this catalog are considered non-hazardous unless otherwise noted.3tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitAcetic Acid-d4 (D,99.5%)DLM-12NMR Solvents[1186-52-3]CD3COODmw 64.08d 1.1210 g25 g50 gCD3COODmw 64.08d 1.1210x0.75 mL5 mLCD3COCD3mw 64.12d 0.8710x0.6 mL10x0.75 mL5x3 mL1L10x1 g3x(10x1 g)10 g10x10 g3x(10x10 g)25 gmw 64.12d 0.8710x1 g3x(10x1 g)10 g10x10 g3x(10x10 g)25 gCD3COCD3mw 64.12d 0.8710x1 g3x(10x1 g)10 g10x10 g3x(10x10 g)25 gCD3COCD3mw 64.12d 0.875x0.5 mL10x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mL5 mLmw 64.12d 0.8710x0.75 mLUN# 2789Acetic Acid-d4 “100%” (D,99.93%)DLM-41[1186-52-3]UN# 2789Acetone-d6 (D,99.9%)DLM-9[666-52-4]UN# 1090Acetone-d6 (D,99.9%) (contains 1% v/v TMS)CD3COCD3DLM-9ta[666-52-4]UN# 1090Acetone-d6 (D,99.9%) (contains 0.05% v/v TMS)DLM-9tb[666-52-4]UN# 1090Acetone-d6 “100%” (D,99.96%)DLM-38[666-52-4]UN# 1090Acetone-d6 “100%” (D,99.96%) (contains 0.03% v/v TMS)DLM-38tc[666-52-4]CD3COCD3UN# 1090Acetonitrile-d3 HPLC grade (D,96-97%)DLM-20[2206-26-0](contains approximately 15-20% D2O) CD3C Nmw 44.07d 0.841LUN# 1648tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com4
Cambridge Isotope Laboratories, Inc.www.isotope.comunitAcetonitrile-d3 (D,96-97%)DLM-22NMR Solvents[2206-26-0]CD3C Nmw 44.07d 0.841LCD3C Nmw 44.07d 0.8410x0.6 mL10x0.75 mL1L10x1 g3x(10x1 g)10 g25 g50 gCD3C Nmw 44.07d 0.8410x0.6 mLCD3C Nmw 44.07d 0.8410x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mL5 mLC6D6mw 84.15d 0.9510x0.6 mL10x0.75 mL10x1 g3x(10x1 g)5g10 g10x10 g25 g50 g100 gC6D6mw 84.15d 0.9510x0.6 mLNEW 10 gC6D6mw 84.15d 0.955x0.5 mL10x0.5 mL5x0.75 mLNEW 10x0.610x0.75 mL5 mLmw 84.15d 1.5210x0.75 mLUN# 1648Acetonitrile-d3 (D,99.8%)DLM-21[2206-26-0]UN# 1648Acetonitrile-d3 (D,99.8%) (contains 0.05% v/v TMS)DLM-21tb[2206-26-0]UN# 1648Acetonitrile-d3 “100%” (D,99.96%)DLM-53[2206-26-0]UN# 1648Benzene-d6 (D,99.5%)DLM-1[1076-43-3]UN# 1114Benzene-d6 (D,99.5%) (contains 0.05% v/v TMS)DLM-1tb[1076-43-3]UN# 1114Benzene-d6 “100%” (D,99.96%)DLM-40[1076-43-3]UN# 1114Benzene-d6 “100%” (D,99.96%) (contains 0.03% v/v TMS)DLM-40tc[1076-43-3]C6D6UN# 11145tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitBromobenzene-d5 (D,99%)DLM-398[4165-57-5]C6D5Brmw 162.04d 1.525g10 g25 gC6D5Clmw 117.59d 1.161g5gCDCl3mw 120.38d 1.5010x0.6 mL10x0.75 mL10x1 g3x(10x1 g)50 g100 g10x100 g3x(10x100 g)mw 120.38d 1.5050 g100 gmw 120.38d 1.5010x1 g3x(10x1 g)50 g100 g10x100 g3x(10x100 g)CDCl3mw 120.38d 1.5010x1 g3x(10x1 g)50 g100 g10x100 g3x(10x100 g)CDCl3mw 120.38d 1.5010x0.25 mL10x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mL10 mL5x10 mL50 gmw 120.38d 1.5010x0.75mLNMR SolventsUN# 2514Chlorobenzene-d5 (D,99%)DLM-263[3114-55-4]UN# 1134Chloroform-d (D,99.8%)DLM-7No stabilizers are used in this product.[865-49-6]UN# 1888Chloroform-d (D,99.8% stabilized with silver d (D,99.8%) (contains 1% v/v TMS)DLM-7taNo stabilizers are used in this product.[865-49-6]CDCl3UN# 1888Chloroform-d (D,99.8%) (contains 0.05% v/v TMS)DLM-7tbNo stabilizers are used in this product.[865-49-6]UN# 1888Chloroform-d “100%” (D,99.96%)DLM-29No stabilizers are used in this product.[865-49-6]UN# 1888Chloroform-d “100%” (D,99.96%) (contains 0.03% v/v TMS)DLM-29tc[865-49-6]No stabilizers are used in this product.CDCl3UN# 1888tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com6
Cambridge Isotope Laboratories, Inc.www.isotope.comunitCyclohexane-d12 (D,99.5%)C6D12DLM-17[1735-17-7]mw 96.23d 0.89NMR SolventsUN# 11455x1 g10x1 g3x(10x1 g)5g10 gDecalin-d18 (D,99%) (Decahydronaphthalene)DLM-1386(cis/trans mixture)[28788-42-3]C10D18mw 156.36d 0.8961g5gC10D18mw 156.36d 0.875gDBrmw 81.92d 1.53710 g (of soln.)50 g (of soln.)mw 37.47d 1.2050 g (of soln.)mw 37.47d 1.305 g (of soln.)25 g (of soln.)mw 37.47d 1.2550 g (of soln.)mw 20.03d 1.111 kgD2Omw 20.03d 1.111 kgD2Omw 20.03d 1.111 kg5 kgD2Omw 20.03d 1.111 kgtrans-Decalin-d18 (D,98%)DLM-1843[493-02-7]Deuterium Bromide (D,99%)DLM-3021[13536-59-9](DBr 48% w/w solution in D2O)Packaged in clear glass ampoules onlyDeuterium Chloride (D,99.5%)DLM-2[7698-05-7](DCl 20% w/w solution in D2O)DClPackaged in clear glass ampoules onlyDeuterium Chloride “100%” (D,99.96%)DLM-54[7698-05-7](DCl 20% w/w solution in D2O)DClPackaged in clear glass ampoules onlyDeuterium Chloride (D,99.5%)DLM-3[7698-05-7](DCl 35% w/w solution in D2O)DClPackaged in clear glass ampoules onlyDeuterium Oxide (D,70%)DLM-4-70[7789-20-0]D2OUN# 1957Deuterium Oxide (D,70%) (sterility tested)DLM-2259-70[7789-20-0]UN# 1957Deuterium Oxide (D,99%)DLM-4-99[7789-20-0]UN# 1957Deuterium Oxide (D,99.8%)DLM-4-99.8[7789-20-0]UN# 19577tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitDeuterium Oxide (D,99.8%) (sterility tested)DLM-2259[7789-20-0]D2Omw 20.03d 1.11D2Omw 20.03d 1.11NEW 100mL250 mL1LNMR SolventsUN# 1957Deuterium Oxide (D,99.9%)DLM-4[7789-20-0]25 g100 g5x100 g10x100 g1000 g1 L InquireUN# 1957Deuterium Oxide (D,99.9%) (glass distilled, low paramagnetic, low conductivity)DLM-11[7789-20-0]D2Omw 20.03d 1.11100 gmw 20.03d 1.1110x0.6 mL5x0.7 mL10x0.7 mL5x(10x0.7 mL)10x1 g1000 gmw 20.03d 1.1110 g50 gmw 20.03d 1.1110x0.7 mLUN# 1957Packaged in plastic bottles onlyDeuterium Oxide “100%” (D,99.96%)DLM-6[7789-20-0]D2OUN# 1957Deuterium Oxide “100%” (D,99.96%)DLM-6-s[7789-20-0]D2OUN# 1957Packaged in serum bottles with Teflon coated rubber septum topsDeuterium Oxide “100%” (D,99.96%) (contains 0.01 mg/mL DSS)DLM-6DB[7789-20-0]D2OUN# 1957Deuterium Oxide “100%” (D,99.96%) (highest purity, glass distilled, low paramagnetic, low conductivity)DLM-1172[7789-20-0]mw 20.03d 1.1110 gBr(CD2)2Brmw 191.87d 2.2010 g25 gC6D4Cl2mw 151.03d 1.301g5gCl(CD2)2Clmw 102.98d 1.301g5x1 g5gD2OUN# 1957Packaged in plastic bottles only1,2-Dibromoethane-d4 (D,99%)DLM-195[22581-63-1]UN# 16051,2-Dichlorobenzene-d4 (D,99%)DLM-158[2199-69-1]UN# 15911,2-Dichloroethane-d4 (D,99%)DLM-18[17060-07-0]UN# 1184tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com8
Cambridge Isotope Laboratories, Inc.www.isotope.comunitDiethyl Ether-d10 (D,99%)DLM-1592[2679-89-2](CD3CD2)2O1g5x1 g5gmw 84.18d 0.82NMR SolventsUN# 1155Packaged in ampoules onlyDiglyme-d14 (D,98%)DLM-47[38086-00-9](CD3OCD2CD2)2Omw 148.26d 1.035Please inquireN,N-Dimethylformamide-d7 (D,99.5%) (DMF)DLM-25[4472-41-7]DCON(CD3)2mw 80.14d 1.045x1 g10x1 g5g10 gmw 80.14d 1.0410x0.6 mLmw 84.17d 1.1810x0.6 mL10x0.75 mL5x3 mL10x1 g3x(10x1 g)5g10 g10x10 g3x(10x10 g)25 g50 gNEW 1000 gmw 84.17d 1.1810 g25 gmw 84.17d 1.1810x1 g3x(10x1 g)5g10 g10x10 g3x(10x10 g)25 g50 gmw 84.17d 1.1810x0.6 mL10x0.75 mL10x1 g3x(10x1 g)5g10 g10x10 g3x(10x10 g)25 g50 gPackaged in ampoules onlyN,N-Dimethylformamide-d7 (D,99.5%) (contains 0.05% v/v TMS) (DMF)DLM-25tb[4472-41-7]DCON(CD3)2Packaged in ampoules onlyDimethyl Sulfoxide-d6 (D,99.9%) (DMSO)DLM-10[2206-27-1]CD3SOCD3Dimethyl Sulfoxide-d6 (D,99.9%) (DMSO)DLM-10-s[2206-27-1]CD3SOCD3Packaged in serum bottles with Teflon coated rubber septum topsDimethyl Sulfoxide-d6 (D,99.9%) (contains 1% v/v TMS) (DMSO)DLM-10ta[2206-27-1]CD3SOCD3Dimethyl Sulfoxide-d6 (D,99.9%) (contains 0.05% v/v TMS) (DMSO)DLM-10tb[2206-27-1]9CD3SOCD3tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitDimethyl Sulfoxide-d6 “100%” (D,99.96%) (DMSO)NMR Solventsmw 84.17d 1.1810x0.25 mL5x0.5 mL10x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mL5 mLCD3SOCD3mw 84.17d 1.1810x0.75 mLC4D8O2mw 96.15d 1.135x1 g10x1 g3x(10x1 g)5g10 g25 gCD3SOCD3DLM-34[2206-27-1]Dimethyl Sulfoxide-d6 “100%” (D,99.96%) (contains 0.03% v/v TMS) (DMSO)DLM-34tc[2206-27-1]1,4-Dioxane-d8 (D,99%) (p-Dioxane)DLM-28[17647-74-4]UN# 1165DSS — D2O reference standard (Sodium cal Purity: 97%[2039-96-5](CH3)3Si(CH2)3SO3Namw 218.311g10 g50 gUN# 1165Ethanol-d (D,99%) (Contains 6% D2O) (Ethyl Alcohol)DLM-16[925-93-9]mw 47.08d 0.8950 g2x50 gmw 52.11d 0.895x1 g10x1 g5gCD3CD2ODmw 52.11d 0.895x1 g5gDOCD2CD2ODmw 68.11d 1.1135gC6D5Fmw 101.13d 1.081gCD3(CD2)5CD3mw 116.30d 0.7941g5gCH3CH2ODUN# 1170Ethanol-d6 (D,99%) (anhydrous) (Ethyl Alcohol)DLM-31[1516-08-1]CD3CD2ODPackaged in ampoules onlyEthanol-d6 (D,99%) (Contains 6% D2O) (Ethyl Alcohol)DLM-31B[1516-08-1]Ethylene Glycol-d6 (D,98%)DLM-132[107-21-1]Fluorobenzene-d5 (D,98%)DLM-617[1423-10-5]UN# 2387n-Heptane-d16 (D,98%)DLM-423[33838-52-7]UN# 1206tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com10
Cambridge Isotope Laboratories, Inc.www.isotope.comunitHexafluoroacetone Trideuterate (D,99.5%)NMR Solventsmw 226.11d 1.7110 g(CF3)2CDODmw 170.05d 1.601g5x1 g5g10 gCD3(CD2)4CD3mw 100.26d 0.7671g5gCF3COCF3 3 ropanol-d2 (D,98%) (Hexafluoroisopropyl Alcohol, HFIP)DLM-143[38701-74-5]n-Hexane-d14 (D,98%)DLM-139[21666-38-6]UN# 1208Isopropanol-d8 (D,99%) (2-Propyl Alcohol)DLM-44[22739-76-0](CD3)2CDODmw 68.14d 0.905g25 gLiODmw 24.96d 1.21825 g100 gCH3ODmw 33.05d 0.8150 g2x50 gCD3ODmw 36.07d 0.8910x0.6 mL10x0.75 mL1L10x1 g3x(10x1 g)5g10 g10x10 g25 g50 gCD3ODmw 36.07d 0.8910 g25 g50 gmw 36.07d 0.8910x0.6 mL10x0.75 mL10x1 g10 g10x10 gUN# 1219Lithium Deuteroxide (D,99.5%)DLM-2173[12159-20-5](3N in D2O solution)Packaged in plastic bottles onlyMethanol-d (D,99%) (Methyl Alcohol)DLM-15[1455-13-6]UN# 1230Methanol-d4 (D,99.8%) (Methyl Alcohol)DLM-24[811-98-3]UN# 1230Methanol-d4 (D,99.8%) (Methyl Alcohol)DLM-24-s[811-98-3]UN# 1230Packaged in serum bottles with Teflon coated rubber septum topsMethanol-d4 (D,99.8%) (contains 0.05% v/v TMS) (Methyl Alcohol)DLM-24tb[811-98-3]CD3ODUN# 123011tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitNMR SolventsMethanol-d4 “100%” (D,99.95%) (Methyl Alcohol)DLM-51[811-98-3]CD3ODmw 36.07d 0.89C6D11CD3mw 112.27d 0.8810x0.25 mL5x0.5 mL10x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mLUN# 1230Methylcyclohexane-d14 (D,99.5%)DLM-288[10120-28-2]1g5gUN# 2296Methylene Chloride-d2 (D,99.9%) (Dichloromethane)CD2Cl2DLM-23[1665-00-5]mw 86.95d 1.3510x0.75 mL5x3 mL5x1 g10x1 g3x(10x1 g)5g10 g25 gmw 86.95d 1.3510x0.6 mLmw 86.95d 1.3510x0.5 mL10x0.6 mL5x0.75 mL10x0.75 mL5 mLUN# 1593Methylene Chloride-d2 (D,99.9%) (contains 0.05% v/v TMS) (Dichloromethane)CD2Cl2DLM-23tb[1665-00-5]UN# 1593Methylene Chloride-d2 “100%” (D,99.96%) (Dichloromethane)CD2Cl2DLM-55[1665-00-5]UN# 1593N-Methyl-2-pyrrolidinone-d9 (D,97%-99%) (NMP)DLM-1988-97[185964-60-7]NOmw 108.19 Please inquired 1.026CD3Nitric Acid-d (D,99%)DLM-3037[13587-52-5](65-70% w/w solution in D2O)DNO3mw 64.02d 1.0265 g (of soln.)25 g (of soln.)Packaged in clear glass ampoules onlyNitrobenzene-d5 (D,99%)DLM-294[4165-60-0]C6D5NO2mw 128.14d 1.255g10 g25 gCD3NO2mw 64.06d 1.2010 g25 gUN# 1662Nitromethane-d3 (D,99%)DLM-30[13031-32-8]UN# 1261tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com12
Cambridge Isotope Laboratories, Inc.www.isotope.comunitn-Octane-d18 (D,99%)NMR SolventsDLM-50[17252-77-6]CD3(CD2)6CD3mw 132.34d 0.8151g5gCD3(CD2)3CD3mw 84.22d 0.731g5gD3PO4mw 101.01d 1.74C5D5Nmw 84.13d 1.055x1 g10x1 g3x(10x1 g)10 g25 g50 gC5D5Nmw 84.13d 1.0510x0.6 mL5x1 g10x1 g3x(10x1 g)10 g25 g50 gC5D5Nmw 84.13d 1.055x0.5 mL10x0.5 mL5x0.75 mL10x0.75 mL5 mLNaODmw 41.00d 1.4650 gmw 41.00d 1.4650 g100 gUN# 1262n-Pentane-d12 (D,98%)DLM-1213[2031-90-5]UN# 1265Phosphoric Acid-d3 (D,99%)DLM-1132[14335-33-2](approximately 85% w/w solutionin D2O)50 g100 gPyridine-d5 (D,99.5%)DLM-13[7291-22-7]UN# 1282Pyridine-d5 (D,99.5%) (contains 0.05% v/v TMS)DLM-13tb[7291-22-7]UN# 1282Pyridine-d5 “100%” (D,99.94%)DLM-39[7291-22-7]UN# 1282Sodium Deuteroxide (D,99.5%)DLM-57[14014-06-3](NaOD 30% w/w solutionin D2O)Packaged in polyethylene bottlesUN# 1282Sodium Deuteroxide (D,99.5%)DLM-45[14014-06-3](NaOD 40% w/w solutionin D2O)UN# 1282NaODPackaged in polyethylene bottlesSulfuric Acid-d2 (D,99%)DLM-33[13813-19-9]UN# 128213(96-98% solution in D2O)D2SO4mw 100.09d 1.8650 gPackaged in clear glass ampoules onlytel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, 2 (D,99.6%) (TCE)NMR SolventsDLM-35[33685-54-0]5g10 g100 gCl2CDCDCl2mw 169.86d 1.62C4D8Omw 80.16d 0.9910x0.75 mL5x3 mL5x1 g10x1 g3x(10x1 g)5g10 gC4D8Omw 80.16d 0.9910x0.5 mL10x0.75 mL5 mL(CH3)4Simw 88.22d 0.6450 g(CH3)3SiCD2CD2CO2Namw 172.27d 1.521g5x1 g5gC6D5CD3mw 100.19d 0.9410x1 g3x(10x1 g)5g10 g25 gC6D5CD3mw 100.19d 0.945x0.5 mL10x0.5 mL5x0.75 mL10x0.75 mL5 mLCF3COODmw 115.03d 1.5010x0.75 mL10x1 g10 g25 g4x25 gmw 102.05d 1.451g5gUN# 1702Tetrahydrofuran-d8 (D,99.5%) (THF)DLM-36[1693-74-9]UN# 2056Packaged in ampoules onlyTetrahydrofuran-d8 “100%” (D,99.95%) (THF)DLM-56[1693-74-9]UN# 2056Tetramethylsilane (TMS)DLM-43[75-76-3](NMR grade)Chemical Purity: 99.9%TMSP-2,2,3,3-d4 (D,98%) (Sodium 3-Trimethylsilylpropionate)DLM-48[24493-21-8](D2O ref er ence standard)Toluene-d8 (D,99.5%)DLM-5[2037-26-5]UN# 1294Toluene-d8 “100%” (D,99.94%)DLM-42[2037-26-5]UN# 1294Trifluoroacetic Acid-d (D,99.5%)DLM-46[599-00-8]UN# 2699Packaged in ampoules only2,2,2-Trifluoroethanol-d2 (D,98%) (Trifluoroethyl Alcohol)DLM-2318[77253-67-9]CF3CD2OHtel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com14
Cambridge Isotope Laboratories, Inc.www.isotope.comunit2,2,2-Trifluoroethanol-d3 (D,99%) (Trifluoroethyl Alcohol)[77253-67-9]NMR Solventsmw 103.06d 1.451g5x1 gCF3CD2ODmw 103.06d 1.451g5gH2Omw 18.02d 1.00CF3CD2ODDLM-272,2,2-Trifluoroethanol-d3 “100%” (D,99.85%) (Trifluoroethyl Alcohol)DLM-58[77253-67-9]Water, Deuterium DepletedDLM-52(2-3 ppm Deuterium)[7732-18-5]NEW25 g100 g1,3,5-Trimethyl Benzene (D12, 98%) (Mesitylene)DLM-3105[69441-16-3]C6D3(CD3)3mw 132.265gC6D4(CD3)2mw 116.23d 0.9535gC6D4(CD3)2mw 116.23d 0.9485gUN# 2325o-Xylene-d10 (D,98%)DLM-808[56004-61-6]UN# 1307p-Xylene-d10 (D,98%)DLM-313[41051-88-1]UN# 1307CARBON-12 AND CARBON-12/DEUTERIUM LABELED SOLVENTS (Carbon-13 Depleted)Benzene (12C6,99.95%)CLM-867(13C depleted)[71-43-2]*C6H6mw 78.05*CDCl3mw 120.38*CH3OHmw 32.040.8 mLChloroform (12C,99.95%;D,99%)CDLM-844(13C depleted)[865-49-6]Please inquireMethanol (12C,99.95%) (Methyl Alcohol)CLM-2472(13C depleted)[67-56-1]1gMethanol (12C,99.95%;D4,99.5%) (Methyl Alcohol)CDLM-01(13C depleted)[811-98-3]*CD3OD0.8 mL5gmw 36.07NMR Reference StandardsAs the leading supplier of NMR reference standards to the world’s largest NMR manufacturers, CIL has an extensive offering ofNMR reference standards. Accompanied by a com plete technical data package, these standards help to as sure prop er spec trom e terperformance. CIL’s total quality assurance protocols and in-house manufacturing capabilities guar an tee the high est stan dard of qualitythe first time and every time. These NMR Reference Standards have been evaluated and determined to meet or exceed industryrequirements. A representative listing of these NMR Reference Standards is provided below. We also welcome your requests for customformulations of oth er ref er ence stan dards as well as alternate fill heights of existing reference standards. Please contact us ifyou require a reference standard that is not listed below. CIL routinely produces other reference standards which are generallyavailable from stock.1% 1,2-Dichlorobenzene in Acetone-d6 (99.9%D)DLM-795mm x 8”Application: 1H-Resolution0.1% Ethylbenzene 0.01% TMS in Chloroform-d “100%” (99.96%D)DLM-74155mm x 8”Application: 1H-Sensitivitytel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunit1% 3-Heptanone in Chloroform-d (99.8%D)NMR SolventsDLM-675mm x 8”Application: 1H APT Test12% TMS in ChloroformULM-735mm x 8”Application: 1H-Reference/Calibration5% Ethylbenzene 2% TMS in Chloroform-d (99.8%D)DLM-845mm x 8”Application: 1H-Sensitivity/Reference1% Chloroform in Acetone-d6 (99.9%D)DLM-765mm x 8”Application: 1H-Line Shape0.1 mg/mL GdCl3 6H2O in D2O (99.96%D)DLM-905mm x 8”Application: 1H-Homogeneity40% p-Dioxane in Benzene-d6 (99.6%D)DLM-725mm x 8”Application: 13C-Sensitivity/Resolution30% Menthol (by weight) in Chloroform-d (99.8%D)DLM-665mm x 8”Application: 13C App Test90% Formamide in DMSO-d6 (99.9%D)DLM-685mm x 8”Application: 15N-Sensitivity0.0485 M Triphenylphosphate in Chloroform-d (99.8%D)DLM-775mm x 8”Application: 31P-Sensitivity0.05% a,a,a,-Trifluorotoluene in Benzene-d6 (99.6%D)DLM-785mm x 8”Application: 19F-Sensitivity0.1% Methanol-13C 0.3 mg/mL GdCl3 in 98.9% D2O 1% H2OCDLM-1005mm x 8”Application: Auto Test Sample0.1 mg/mL GdCl3 0.1% DSS in 20% H2O in D2ODLM-885mm x 8”Application: Gradient Shimming1% 13CH3I, 0.2% CR(acac)3 1% (CH3O3)P in CDCl3 “100%”CDLM-965mm x 8”Application: Indirect Detection Test0.2% Cr(acac)3 2% Benzamide (15N,98% ) in DMSO-d6 “100%” (99.96%D)DNLM-975mm x 8”Application: Indirect Detection Test100% Ethylene GlycolULM-715mm x 8”Application: High Temperature Calibrant100% MethanolULM-695mm x 8”Application: Low Temperature Calibrant10% TMS in MethanolULM-92new5mm x 8”Application: Low Temperature Measurement0.1M Urea-15N 0.1M MeOH-13C in DMSO-d6 100%5mm x 8”CDNLM-5003 Application: Indirect Detection Experiments50mM Sodium Acetate 1% Water in Deuterium OxidePlease inquireDLM-5032-50mL Application: Homogeneity Standard1% Water in Deuterium OxideDLM-7005Please inquireApplication: Homogeneity Standardtel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com16
Cambridge Isotope Laboratories, Inc.www.isotope.comNMR SolventsunitSince 2006, CIL has partnered with Norell to offer our customers the convenience and quality of purchasing oursolvents and Norell’s standard and select series NMR tubes together. CIL offers Norell NMR tubes in North Americaonly. International customers should contact their local independent distributor.Norell Tubes (Sold only in North America)5 mm, 100 Mhz, 7” Standard Series502-750 PackNMR Tube5 mm, 100 Mhz, 8” Standard Series502-850 PackNMR Tube5 mm, 200 Mhz, 7” Select SeriesS-5-200-75 PackNMR Tube5 mm, 200 Mhz, 8” Select SeriesS-5-200-85 PackNMR Tube5 mm, 300 Mhz, 7” Select SeriesS-5-300-75 PackNMR Tube5 mm, 300 Mhz, 7” Standard SeriesXR-55-725 PackNMR Tube5 mm, 300 Mhz, 8” Select SeriesS-5-300-85 PackNMR Tube5 mm, 300 Mhz, 8” Standard SeriesXR-55-825 PackNMR Tube5 mm, 400 Mhz, 7” Select SeriesS-5-400-75 PackNMR Tube5 mm, 400 Mhz, 7” Standard Series507-HP-75 PackNMR Tube5 mm, 400 Mhz, 8” Select SeriesS-5-400-85 PackNMR Tube5 mm, 400 Mhz, 8” Standard Series507-HP-85 PackNMR Tube5 mm, 500 Mhz, 7” Select SeriesS-5-500-75 PackNMR Tube5 mm, 500 Mhz, 7” Standard Series508-UP-75 PackNMR Tube5 mm, 500 Mhz, 8” Select SeriesS-5-500-85 PackNMR Tube5 mm, 500 Mhz, 8” Standard Series508-UP-85 PackNMR Tube5 mm, 600 Mhz, 7” Select SeriesS-5-600-7175 PackNMR Tubetel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com
Cambridge Isotope Laboratories, Inc.www.isotope.comunitNMR SolventsUse and Handling of NMR SolventsCIL has implemented extensive quality control protocols for the evaluation of chemical and isotopic purities of our solvents.CIL understands that the increase in sensitivity and resolution of today’s high field NMR instruments requires solvents withthe highest chemical purity as well as high isotopic enrichment. Each lot of our NMR solvents receives thorough qualitycontrol testing before being released for shipment. All ampoules and bottles are clearly marked with both a production anda packaging lot number for easy tracking in the unlikely event that a problem should occur.Water PeaksWater contamination is a common problem for deuterated NMR solvents. There are several things that canbe done to minimize/eliminate water peaks. Consider using single-use ampoules. Many of our solvents are available in single-use breakseal ampoulesranging in size from 0.25 mL to 3 mL. Handle solvents in a dry atmosphere. Dry NMR tubes and pipettes used for sample preparation overnight in an oven and cool them in a dessicatorprior to use. Precondition an NMR tube by rinsing it with D2O. Remove residual D2O by rinsing first with methanol-D4 or acetone-D6and then with the solvent of choice. This process will not remove water, but it will exchange the protons for deuteriumand minimize the water peak.“100%” D2OTo avoid loss of enrichment due to exchange with ambient moisture, “100%” D2O stored in a serum bottle should besampled with a syringe that has been preflushed with dry nitrogen. Additionally, a volume of dry nitrogen equal to theamount of D2O being removed should be injected into the serum bottle prior to withdrawing D2O.TMS EvaporationWhen stored at room temperature (unless noted below) and properly capped, solvents containing TMS should not sufferfrom TMS evaporation. However, upon extended storage of these solutions, some loss of TMS may occur.StorageAll serum bottles should be stored upright in the refrigerator; we do not recommend freezing. We also recommend thatchloroform, diethyl ether, diglyme, tetrahydrofuran, and TMS be stored in the refrigerator.Deuterated ChloroformThe deuterated chloroform produced at CIL is of the highest chemical purity. Over time chloroform will decomposeregardless of the storage container or conditions. Over many months of storage at room temperature (for example,in a stockroom), deuterated chloroform can become acidic. However, decomposition is minimized if bottles are storedrefrigerated in the dark.CIL takes several precautions during production and packaging of chloroform-d to further minimize decomposition.Exposure to oxygen is minimized by using an argon atmosphere during production and packaging. Amber bottles areused to protect the product from light. Finally, silver foil is added to the solvent to act as a radical scavenger, which helpsto stabilize the material over time.Quality Control of Deuterated ChloroformTo ensure the highest quality, CIL routinely tests each batch of solvent for chemical and isotopic purity. The chemical purityis monitored during production and packaged using 1H NMR, GC, Karl-Fisher titration for total water content and other wetchemical methods for acidity and various impurities.Proper Storage and Use of Deuterated ChloroformUnopened bottles of chloroform-d should be refrigerated (-5 C to 5 C) to maximize shelf life. Moisture and oxygen willbe introduced to the solvent following initial use through air entering the bottle upon opening. Decomposition can followwhich results in the deuterated chloroform becoming acidic. The acidity can be easily tested using the following method:tel: 978-749-8000 800-322-1174 (USA)fax: 978-749-2768cilsales@isotope.com18
Cambridge Isotope Laboratories, Inc.www.isotope.comNMR SolventsunitTesting Deuterated Chloroform AcidityA 1mL aliquot of the solvent is added to a test tube containing 1 mL of distilled water (pH 5.0-7.0) and 2 drops ofBromothymol Blue (0.04% W/V). The color is compared to a 2 mL blank of distilled water (pH 5.0 – 7.0). If the samplesolution is discolored (yellow) relative to the blank (blue-green), the deuterated chloroform is acidic.Samples of deuterated chloroform which have become acidic can be easily neutralized using the following procedure: Place 3-5 grams of a 5Å molecular sieves into a 50 or 100g bottle of the solvent. Swirl slightly and allow to stand overnight. Excess water and traces of acidity will be removed. This is also thepreferred way to store chloroform-d bottles once they have been opened, as it will keep the solvent dry andstable over time. Maintain an inert atmosphere (argon or nitrogen) in the bottle. Small “dust or powder” particles may break off from the molecular sieves. However, these particles can be removedsimply by filtering the quantity of deuterated chloroform needed for an NMR sample through a small plug of glasswool or cotton in a glass pipette.Special Applications Which Require Ultra Dry and Acid Free Deuterated ChloroformFor applications involving highly acid-sensitive or moisture-sensitive compounds, deuterated chloroform can be purifiedfurther prior to use. Solvents treated in the following manner will be exceptionally dry and acid free. Place a glass wool plug into a disposable glass pipette ( 7mm diameter). Add dry alumina powder into the pipette to a height of 3-4 cm. Pass the solvent through the small alumina bed into the sample container containing the product to be analyzed. Analyze the sample as soon as possible.This procedure will ensure that the deuterated chloroform is dry and free of trace amounts of acid prior to contact withthe sample. Note that the chloroform will react with basic compounds, such as alkaloids or amines. If the product is tobe recovered, this should take place as soon as possible to minimize possible reaction.NMR Solvent Technica
NMR SOLVENTS Deuterated Solvents for NMR NMR Solvents NMR Reference Standards NMR Tubes. Cambridge Isotope Laboratories, Inc. www.isotope.com s tel: 978-749-8000 800-322-1174 (USA) fax: 978-749-2768 cilsales@isotope.com TABLE OF CONTENTS
Aug 01, 2018 · 1H NMR, 19F NMR, 31P NMR experiments -about 3 5 mg 13C NMR short run experiment (0.5 -1 hr) about 20 50 mg; long run experiment about 5 10 mg 0.6-0.7 ml of NMR solvent is appropriate for the right solvent level in NMR tube. Unsuitable solvent level can lea
1985 –First Protein Structure solved by NMR 2009 –First 1 Gigahertz NMR Spectrometer (23.5 T) 2019 –High Temperature Superconducting Magnets 1.1 GHz NMR, St. Jude, Memphis TN 1.2 GHz NMR, Florence, Italy 1938 –NMR of LiCl molecular beams. Rabi (Columbia University) 1946 –NMR
Figure 2.1 1H-NMR of methyl 2,4-dihydroxy-5-nitrobenzoate 4 in deuterated DMSO 14 Figure 2.2 EI-MS of methyl 2,4-dihydroxy-5-nitrobenzoate 4 15 Figure 2.3 1H-NMR of 2-nitroresorcinol 5 in deuterated acetone 16 Figure 2.4 EI-MS of 2-niroresorcinol 5 16 Figure 2.5 1H-NMR o
5 Experiment 8.16 - Quantitative 13C NMR Spectroscopy with Inverse Gated 1H-Decoupling 68 Experiment 8.17 - NMR Using Liquid-Crystal Solvents 68 CHAPTER 9 - HETERONUCLEAR NMR SPECROSCOPY 70 SUMMARY 70 Experiment 9.1 - 1H-Decoupled 15N NMR Spectra with DEPT 70 Experiment 9.2 - 1H-Coupled 15N NMR Spectra
Solvents Nonpolar solvents: Chapter 2 -23 Solvents “Borderline” Polar aprotic solvents: - These solvents have moderately higher dielectric constants than the nonpolar solvents (between 5 and 20). - Since they have intermediate polarity they are good “general purpose” solvents
Bruksanvisning för bilstereo . Bruksanvisning for bilstereo . Instrukcja obsługi samochodowego odtwarzacza stereo . Operating Instructions for Car Stereo . 610-104 . SV . Bruksanvisning i original
5 nuclear magnetic resonance (nmr) spectroscopy 33 5.1 the physics of nuclear spins and nmr instruments 33 5.2 continuous wave (cw) nmr spectroscopy 37 5.3 fourier-transform (ft) nmr spectroscopy 39 5.4 chemical shift in 1h nmr spectroscopy 40 5.5 spin-spin coupling in 1h nmr spectroscopy 50
Kirsty Harris (Anglia Ruskin University) Now and in Ireland. Chair: Beatrice Turner (Newcastle University) Exile, Emigration and Reintegration: The journeys of three United Irish poets . Jennifer Orr (Trinity College Dublin) Cross-cultural borrowings and colonial tensions in the elegies on the death of Robert . Emmet . Alison Morgan (University of Salford) Anacreontic Imports: Thomas Moore and .
