ISSUE 65 BUILDING BRIDGES TROUGH TOXICOLOGY
WINTER ISSUE JANUARY – FEBRUARY 2021ISSUE 65BUILDING BRIDGES TROUGH TOXICOLOGYHOT AwardeesHOT Posters and TalksHOT Letter.asp
HOT OFFICERSEnrique Fuentes Mattei, Ph.D.PresidentM E S S A G EF R O MT H EP R E S I D E N TAline de Conti, Ph.D.Vice PresidentDear HOT members,Teresa Palacios-Hernández, Ph.D.Vice President-ElectJulieta Martino, Ph.D.SecretaryRanulfo Lemus Olalde, Ph.D.Past PresidentVinicius de Paula Venancio, Ph.D.TreasurerCarmen Rubio-Armendáriz, Ph.D.CouncilorMichelle Hernández, Ph.D.CouncilorPatricia Ruiz, Ph.D.CouncilorMercedes Salvador-Silva, Ph.D.CouncilorVacantPostdoctoral RepresentativeHenry LujanGraduate Student RepresentativeJulia Rezende da SilvaToxenlaces EditorGeneral Contacthispanicorgtox@gmail.comWe hope you all and your families are well and safe!On behalf of the HOT Executive Committee (EC) it is my pleasure to inviteyou to join us during the very anticipated 2021 SOT Virtual Annual Meeting,the 2021 HOT Annual Awards Ceremony & Reception (see page 4), and thevirtual event Session on Strategies to Increase Global Awareness ofToxicology: Focus on Developing Countries (see page 5). We are very proudof the outstanding work of the HOT EC members during this unprecedentedtime with the CoViD-19 pandemic and unexpected challenges that hasimpacted us all, directly or indirectly.We want to take the time and thank our HOT membership for yourparticipation in both the HOT EC and SOT general election process duringthese unprecedented times. We are very excited and happy to welcome ournew HOT EC member Dr. Veronica Ramirez-Alcaraz (Vice-PresidentElect), Dr. Kelly Salinas (Treasurer), Dr. Alexandra M. Moita (Councilor),Dr. Federico L. Sinche (Councilor), Dr. Isabel Alvarado-Cruz (PostdoctoralRepresentative), and Mr. Jose F. Delgado (Student Representative). In thesame way, the HOT-SIG is very proud to have several HOT members orstrong HOT supporters nominated to serve as officers and members of SOTelected committees during 2021–2022. We want to congratulate two of ourHOT Past-Presidents Dr. Elena Hernandez Ramón and Dr. Pedro L. DelValle for being elected to the SOT Membership Committee and the SOTAwards Committee, respectively.With the outstanding leadership of our Councilor, Dr. Carmen RubioArmendáriz, we continue reinforcing our current bridge and adding newbridges with sister organizations. Moreover, with the outstanding leadershipof Julia Rezende da Silva, we keep reaching you all via ToxEnlaces andFacebook. A special thanks to our donors to help us keep promoting thecareer development of trainees/scientists of Iberoamerican (Latin-Americanscountries, Spain, and Portugal) in toxicology by providing the funds for theHOT awards and the HOT Endowment Funds. We strongly encourage todonate by visiting the SOT’s endowment fund website. We stronglyencourage you to donate money (any amount will help) to our recentlyestablished Endowment Fund and/or look for Sponsors for our TravelAwards (see page 12).Looking forward to seeing you soon at the 2021 SOT Virtual AnnualMeeting events! Stay safe and continue working hard to create a safer andhealthier world by advancing science and increasing the impact oftoxicology. And remember, together we can continue building bridges withtoxicology!Un fuerte abrazo!#IamHOTEnrique Fuentes-Mattei, Ph.D.HOT President
ContentsTO X E N L AC E S WI NTER I SSUE J AN U AR Y – F E B R U AR Y 2 0 2 1469HOT Activitiesat SOTHOT AchievementsHOT Executive CommitteeHOTAwardeesEDITORIAL BOARDJulia Rezende da Silva10HOT Posters and Talks12Support HOTJulieta MartinoAline de ContiTeresa Palacios-HernándezCarmen Rubio Armendáriz3
Do not miss the opportunity to attendour traditional HOT Annual Reception!And yes, we are still going to have ourvirtual SALSA DANCING!March 25th, 4:15 PM to 5:45 PM ETHOT SESSION:GLOBALAWARENESSOFTOXICOLOGYHOT ANNUALAWARDSCEREMONYANDRECEPTIONIf you are a toxicologist interested ininternational networking, this is agreat opportunity to improve yourknowledge in toxicology withoutstanding speakers!March 23rd, 11:15 AM ETREGISTER egistration.asp#Register-now4
ANNOUNCEMENTSTRATEGIES TO INCREASE GLOBAL AWARENESS OF TOXICOLOGY: FOCUS ONDEVELOPING COUNTRIESTuesday, March 23, 2021Session Time: 11:15 AM-2:00 PM US Eastern TimeSOT and IUTOX Efforts to Promote Toxicology Global OutreachProf. Jose ManautouDept. Head of Pharmaceutical SciencesAssistant Dean for Graduate Education and Research andProfessor of Toxicology, School of Pharmacy, University of ConnecticutPresident elected of the International Union of Toxicology (IUTOX)International Mentoring as a Tool to Promote Toxicology Higher Education and GlobalOutreachDr. Zafira Castano CorsinoPresident/Co-Founder International Mentoring Foundation for the Advancement of HigherEducation (IMFAHE), Boston, MASenior Scientist Rubius Therapeutics, Cambridge, MA, USAInternationalization of Research to Improve Diversity and Quality of ScienceProf. Silvia Berlanga de Moraes BarrosSenior Professor, Skin Biology Group, School of Pharmaceutical Sciences, Clinical Chemistryand Toxicology Department, University of Sao Paulo.Director IUTOX (2019-2022)Past-President Hispanic Organization of Toxicologists-HOT/SOT (2019-2020)Challenges for Toxicological Sciences in Latin AmericaProf. Jesus Olivero-VerbelEnvironmental and Computational Chemistry Group, School of Pharmaceutical Sciences,Zaragocilla CampusUniversity of Cartagena, ColombiaChallenges for Toxicological Sciences Internationalization in Countries from AfricaProf. Darryl HoodCollege of Public Health, Division of Environmental Health Sciences, The Ohio StateUniversity, Columbus, OH, USAChair: Aline de Conti, Ph.D.Staff Fellow Researcher at National Center for Toxicological Research, Foodand Drug AdministrationVice-president of the Hispanic Organization of ToxicologistsCo-chair: Carmen Rubio Armendáriz, PhDSenior Professor of Toxicology, Universidad de La Laguna, Canary Island,SpainCouncilor of the Hispanic Organization of Toxicologists
SPECIAL ARTICLE2020-2021 Achievements2021-2022 Executive Committee2020-2021 HOT Achievements For the 2021 SOT Virtual Meeting, HOT awarded 1 Distinguished Toxicologist Award and1 Graduate Student Travel Award . Special thank you to our sponsors and congratulationsto all the awardees! In 2020 with the support of SOT, HOT offered the Mentoring Activity “A path of success:Leadership in Toxicology” . The main panelists were: Dr. Silvia Barros, Dr. Pedro Del Valle,Dr. Ofelia Olivero and Dr. Linval DePass, all HOT Past Presidents and leaders in diversetoxicology settings. The webinar had a total of 31 attendees from USA, Brazil, Cuba,Panama, Czech Republic, Mexico and Argentina.AwardsCareerDevelopment6
SPECIAL ARTICLE HOTNewsletter HOT Initiatives HOT signed agreements with two new sister organizations: Sociedade Brasileira deEcotoxicologia (ECOTOX Brasil) and Associação Latino Americana de Patologia Toxicológicae Experimental (ALAPTE). Additionally, HOT renewed its agreement with RedIberoamericana de Toxicología y Seguridad Química (RITSQ). Several HOT members and HOT Past Presidents participated in the “SOT Focus Group withLatinx Members” organized by 2020-2021 SOT President Dr. George P. Daston. This focusgroup served as a platform to share experiences, perspectives, and advice on what additionalwork SOT should do to promote inclusion.Two HOT Past Presidents were nominated and elected for SOT positions: Dr. Pedro DelValle was elected to be part of the Awards Committee and Dr. Elena Hernandez-Ramon waselected for the Membership Committee. HOT also had other nominees participating in theseimportant elections: HOT Past Presidents Dr. Ofelia Olivero and Dr. Silvia Barros , and HOTMembers Dr. Peter Goering and Dr. Kenneth Ramos. We would like to congratulate all thenominees and elected Officers for their involvement in SOT and for representing HOT.InternationalOutreachParticipationin SOTMembershipOur newsletter Toxenlaces welcomed a new Editor: Julia Rezende da Silva, BSc. From April1, 2020-March 1, 2021, 3 Toxenlaces have been published. The HOT newsletter includes aTrainee Section, short Scientific Articles by invited HOT members, HOT Professional Tips,News and achievements from our members, and information on upcoming meetings andopportunities.The communications committee has increased social media outreach to 1,164 followers.For the 2021 SOT Virtual Meeting, HOT organized the informational session “Strategies toIncrease Global Awareness of Toxicology: Focus on Developing Countries”. This session willbe online on Tuesday, March 23, 2021 from 11:15 AM to 2:00 PM (ET). The panelists includeDr. Jose Manautou, Dr. Zafira Corsino, Dr. Silvia Barros, Dr. Darryl Hood, and Dr. JesusOlivero-Verbel. The goals of this session are to highlight the strengths and challenges oftoxicological international outreach models in order to maximize the potential to benefitindividuals and institutions, and to discuss new strategies to increase the perception andapplication of toxicology around the world. HOT has 185 members, both students and professionals from over 10 different countriesrepresenting academia, industry, government and other sectors that employ toxicologists.7
SPECIAL ARTICLE2021-2022 Executive CommitteePresidentVice-PresidentAline de Conti, PhDTeresa PalaciosHernández, MSc, PhD Councilors Alexandra Maria MoitaAntunes, PhDPatricia Ruiz, PhDMercedes SalvadorSilva, PhD, DABTFederico LeonardoSinche Chele, PhDVice-President ElectVerónica RamírezAlcantara, PhDPast President(2020-2021)Enrique FuentesMattei, PhDGraduateStudentRepresentativeJosé F. DelgadoSecretaryJulieta Martino, PhDPostdoctoralRepresentativeIsabel Alvarado-Cruz, PhDTreasurerKelly Salinas, PhDToxenlaces EditorJulia Rezende da Silva, BSc8
DistinguishedToxicologist AwardDr. Silvia Berlanga deMoraes BarrosUniversity of SãoPaulo, BrazilGraduate StudentTravel AwardLuma MeloIndiana UniversityHOT wants to congratulate two of our HOT PastPresidents for being elected to SOT Committees!SOT Membership CommitteeDr. Elena Hernandez RamónSOT Awards CommitteeDr. Pedro L. Del Valle9
Abstract TitleCytoskeleton Rearrangement Induced in RAW264.7 Cells byExposure to Organophosphate CompoundsAbstract TitlePredicted binding sites for bisphenol S within the epidermalgrowth factor receptorSession TitlePesticidesSession TitleBiological ModelingAbstract #3106Poster Board #P237Presentation Date24/03/2021Presentation Time1:00:00 PMAuthorsDavid Sebastián Hernández-Toledano, Elizabet EstradaMuñiz, Libia Vega-LoyoAbstract TitleAbstract #2366Poster Board #P104Presentation Date22/03/2021Presentation Time11:15am to 1pmAuthorsJose Villegas, Elvis Ticiani, Almudena Veiga-LopezThe Effects of Endurance Training on High Fat Diet-InducedNonalcoholic Fatty Liver Disease in Male MiceAbstract TitleLow dose triphenyltin upregulates ABCA1 expressionwithout altering intracellular cholesterol in ovarian thecacellsSession TitleLiver: In vivoSession TitleReproductive and Developmental Toxicology IIAbstract #2170Abstract #2709Poster Board #P163Poster Board #P175Presentation Date17/03/2021Presentation Date23/03/2021Presentation Time11:15am-1pmPresentation Time11:15:00 AM to 1:00:00 PMAuthorsYong Pu, Elvis Ticiani, Denny Martin, Sarah Pearl, AlmudenaVeiga-LopezAbstract TitleSex-specific extracellular matrix remodeling duringadipogenic differentiation by gestational bisphenol ASession TitleReproductive and Developmental Toxicology IAbstract #2491AuthorsLuma Melo, Merve Bilici, Amit Hagar, James E KlaunigAbstract TitleIn silico modeling of bisphenols: pregnancy-specificphysiologically-based toxicokinetic models for BPA and BPSSession TitleComputational Toxicology IAbstract #2537Poster Board #P275Presentation Date22/03/2021Presentation Time1:00pm - 2:45pmPoster Board #P229Presentation Date22/03/2021Presentation Time11:15:00 AM to 1:00:00 PMAuthorsElvis Ticiani, Yong Pu, Aniyta Waye, Kunzhe Dong, HuanmingZhang, Almudena Veiga-LopezAbstract TitleValidation of Zebrafish embryotoxicity test (ZET) as aqualified alternative assay for its regulatory useSession TitleReproductive and Developmental Toxicology IIAbstract #2718Poster Board #P184Abstract TitleDavid Filipovic, Jeremy Gingrich, Sudin Bhattacharya,Almudena Veiga-LopezBisphenol S impairs invasion and proliferation of extravilloustrophoblasts through epidermal growth factor receptorbinding inhibitionSession TitleReproductive and Developmental Toxicology IIAbstract #2708Poster Board #P174Presentation Date23/03/2021Presentation Date23/03/2021Presentation Time11:15:00 AM to 1:00:00 PMPresentation Time11:15:00 AM to 1:00:00 PMAuthorsElvis Ticiani, Yong Pu, Almudena Veiga-LopezAuthorsA.Alday, J.C. Solis, A.Muriana, C.QuevedoAuthors10
Abstract TitleDevelopmental and Functional Kidney Toxicity Assay inZebrafish EmbryosSession TitleKidneyAbstract #2132Poster Board #P125Presentation Date17/03/2021Presentation TimeAuthors11:15:00 AM to 1:00:00 PME. Hernández, A.Muriana, MJ. MazónAbstract TitleClinical Management of Poisoned Patients: An EducationalIntervention for Medicine Students of the University ofConcepción, ChileSession TitleAbstract #Education, Ethical, Legal, and Social Issues3061Poster Board #POS-119Presentation Date24/03/2021Presentation TimeAuthors01:00 PM - 02:45 PMMayerlic Urzúa-Farrán, Claudio Müller-RamírezAbstract TitleCirculating HMGB1 Triggers the Persistent Pro-InflammatoryMicroglia Phenotype: Implications for Gulf War IllnessSession TitleNeurotoxicity: GeneralAbstract #2471Poster Board #P209Presentation Date22/03/2021Presentation TimeAbstract Title11:15AM - 2:45 PMCarla Garza Lombo, Morrent Thang, Hendrik Greve, EvanMessenger, Chandrama Ahmed, Christen Mumaw, MichelleL BlockParticulate Hexavalent Chromium Alters microRNAsInvolved in CarcinogenesisSession TitleAbstract #Metals2073Poster Board #P174Presentation Date16/03/2021Presentation Time1:00:00 PM to 2:45:00 PMAuthorsIdoia Meaza, Rachel M. Speer, Jennifer H. Toyoda, Yuan Lu,Qian Xu, Ronald Walter, Maiying Kong, John Pierce Wise, Sr.AuthorsTalk TitleAdvancements on Global Efforts for Protocol Harmonizationfor Zebrafish Toxicology TestingSession TitleThe Need for Protocol Harmonization in the Advancementof Zebrafish as a Model for Toxicological Screening: GlobalPerspectives and Recent AdvancementsPresentation Date18/03/2021Presentation Time11:15 AM to 2:00 PMAuthorsJohn Ball, Celia Quevedo, Manon Beekhuijzen, N. De Croze,B. Flick, N. Powles-Glover, N. De Croze, B. Flick, N. PowlesGlover, A. Letamendia, Arantza Muriana, Steven VanCruchten11
Support HOTMAKE A DONATION TO THE HISPANICORGANIZATION OF TOXICOLOGISTSENDOWMENT FUNDThe goal of the HOT AWARD FUND is to encourage students ofIbero-America (Latin-Americans countries, Spain, and Portugal)heritage to start a career in toxicology. The fund will be used toprovide awards based on scientific excellence and scientificprogress to domestic or international Ibero-american students(undergraduate and graduate students) and postdoctoral fellowswhose studies and research interests are in the toxicologicalsciences, or to those individuals with the objective of promotingglobal outreach by increasing research/academic excellence orleadership. These awards will be given to support thedevelopment of students and postdoctoral fellows throughvarious educational and scientific activities, including, but notlimited to: attendance at international scientific meetings tosupport presenters at scientific programs, symposiums,workshops, courses, internships, etc.This contribution is U.S. tax deductible, it will be recognized onour webpage and in Toxenlaces, but most importantly, it will helptremendously students to achieve their goals.To donate online, please click here andselect HOT Award Fund from the drop down
British Council offers Masters Scholarships to women in Latin AmericaThe British Council and Imperial College London (United Kingdom) offersix master's scholarships at British partner institutions in the fields ofscience, technology, engineering and mathematics (STEM) for femalestudents from Argentina, Brazil, Colombia, Cuba, Jamaica, Mexico,Peru or Venezuela.The opportunities are for the sub-areas of chemical engineering;environmental engineering; climate changes; ecology, evolution a;environmental technology; green chemistry; management of waterresources; international health management; sustainable energies;transport; taxonomy, biodiversity and evolution.Each scholarship covers the total cost of the course, monthly personalcosts and airfare. It also covers the IELTS exam fee, visa, UK healthcarefee and study materials.Applicants must demonstrate the need for financial support and sayhow they can inspire future generations of girls to choose careers inSTEM areas.Candidates can apply until March 26, 2021, via ImperialCollege London website. Academic activities begin inSeptember or October 2021.More information at: https://bit.ly/3uNpNin or byemail student.funding@imperial.ac.uk.Source:14
SPONSORS & SISTER ORGANIZATIONSSponsorsOfelia A. OliveroKrishan & VickyJoshi FoundationMichelle HernandezSister OrganizationsAsociación Española de Toxicologíahttp://www.aetox.es/Asociación Latinoamericana de Toxicologíahttp://www.alatox.org/Associação Latino Americana de Patologia Toxicológicae ExperimentalAsociación Toxicológica ArgentinaAsociación Venezolana de Toxicología MédicaCenter of Environmental and Toxicological Research –University of Puerto 0/?ref brhttp://cetr.rcm.upr.eduEscuela Académico-Profesional de Toxicología de laUniversidad Nacional Mayor de San Marcos, Limahttps://farmacia.unmsm.edu.pe/index.phPLAGBOL – Salud, Agricultura y Medio Ambientehttp://plagbol.org.bo/Red Iberoamericana de Toxicología y Seguridad Químicahttp://www.ritsq.orgSociedade Brasileira de Toxicologiahttp://www.sbtox.org/Sociedade Brasileira de Ecotoxicologiahttps://ecotoxbrasil.org.br/Sociedad Cubana de ociedad Mexicana de Toxicologíahttp://www.somtox.com.mx/Sociedad de Toxicología de Chilehttp://sotox.cl/Society for Risk Analysis Latin Americahttp://www.srala.org/Toxicología Acuática Ambiental, Medicina aUniversidad Nacional de ColombialezmaUniversidad de Cartagenahttp://reactivos.comp/toxicologia/If your Hispanic Organization is planning a Toxicology meeting or if you are organizing a Toxicology event intended for aprimarily Hispanic audience and want to promote in the upcoming Toxenlaces issues, send an email to CarmenRubio Armendáriz (Councilor for Sister Organizations) at crubiotox@gmail.com.15
ANNOUNCEMENTHOT wants you to be part of the organization! To make it available to everyone, HOT acceptsapplications from non-SOT members to become HOT members. Yes, that is right! You only haveto have the desire to collaborate with and be part of our great organization.Your HOT membership provides you with valuable resources throughout your scientific career asfor networking through the largest Hispanic toxicologist community, giving you opportunity forTravel Awards or serving as a mentor to the young Hispanic toxicologists; besides you receive theToxenlaces newsletter!Download the application by clicking on the following link: Non-SOT Member Application.So, what are you waiting for? We are looking forward to receiving your application today!Follow us on Facebook at: cologistsDon’t forget to visit also the SOT Facebook cology-SOT/163627880427831?fref tsToxenlaces is the newsletter that informs Hispanic toxicologists in the United States and theinternational Spanish and Portuguese-speaking scientific communities about importanttoxicologica
Looking forward to seeing you soon at the 2021 SOT Virtual Annual Meeting events! Stay safe and continue working hard to create a safer and healthier world by advancing science and increasing the impact of toxicology. And remember, together we can continue building bridges with toxicology! U
8 · TROUGH SCREW CONVEYOR NEXT LEVEL TROUGH SCREW CONVEYOR NEXT LEVEL 9 CONVEYORS Technical Data Trough Screw Conveyor TSF NL 500 TSF NL 500 3 mm/4 mm/5 mm 5 mm (largest plate gauger for trough) S235 (St37-2), 1.4301 (V2A), 1.4571 (V4A-4) 2000 mm - 8500 mm (in 100 mm increments) ø 500/400 mm pitch/6mm thread blade thickness
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require less cable and can be built much faster than suspension bridges. Cable-stayed bridges are becoming the most popular bridges for medium-length spans (between 500 and 3,000 feet). Lower Mainland Bridges 1) Arthur Lang 2) Oak St 3) Knight St. 4) Queensborough 5) Alex Fraser 6) Pattullo 7) Port Mann 8) Second Narrows 9) Lions Gate
Seminar ‘Bridge Design with Eurocodes’ – JRC Ispra, 1-2 October 2012 13 Materials Concrete : Between C20 and C60 for composite bridges (C 90 for concrete bridges) Steel : up to S460 for steel and composite bridges (S 500 to S 700 in a separate part 1-12 for steel bridges)
Page 1 of 5 Bridges Lesson Plan 5/21/18 Unit Topic: Intro to Bridges Activity Name: Lesson #1, What is Bridges? This lesson plan is a great way to introduce your students to the Bridges Program. This lesson can be used as a student advising tool that provides an interactive acti
ENCE717 – Bridge Engineering Long-Span Bridges Chung C. Fu, Ph.D., P.E. (http: www.best.umd.edu) Classification Based on Main Span Length Short Span Bridges (up to 15m) Medium Span Bridges (up to 50m) Long Span Bridges (50-150m*) Extra Long Span Bridges (over 150m*) * (or 200 m) Long & Extra Long
Beam bridges are the oldest known bridges and tend to be the simplest to design and build. Roughly half of all bridges Roughly half of all bridges in the United States are beam bridges.They consist of vertical piers and horizontal beams.A beam bridge’s strength
Florida Post-Tensioned Bridges 2/15/2002 FINAL REPORT Volume 1 – Use of Post-Tensioning in Florida Bridges 5 of 68 Chapter 1 – Introduction The State of Florida has been, and continues to be, a leader in the development of prestressed concrete bridges in the United States. There are 72 major post-tensioned bridges in Florida
