Pharmacology For Advanced Nursing Practice 3 Units
NURS 504Pharmacology for Advanced NursingPractice 3 UnitsIn modern pharmacology, it’s so clear that even if you have a fixed dose of a drug, theindividuals respond very differently to one and the same dose.—Arvid Carlsson, Nobel Prize in Physiology of Medicine 2000I.Course Prerequisites or CorequisitesRecent (within 5 years), satisfactory completion of undergraduate courses that include Biochemistry,Microbiology, Anatomy and Physiology, and Pharmacology. It is expected that enrolled students havereviewed their undergraduate coursework in Pharmacology and possess a wor king knowledge of cellbiology, biochemistry, microbiology, and human genetics at the undergraduate level.II.Catalogue DescriptionThis is a course in advanced pharmacology including pharmacodynamics, pharmacokinetics, andpharmacotherapeutics of all broad categories of agents.III.Course DescriptionsThis course is a comprehensive review of pharmacological concepts and principles. The course builds onthe pharmacology knowledge base acquired in the baccalaureate nursing program. It focuses on use ofpharmacotherapeutics in health promotion and the treatment of disease. The interrelationships of nursingand drug therapy will be explored through study of pharmacodynamics, dynamics of patient response tomedical and nursing therapeutic regimens, and patient teaching as well as the psychosocial, economic,cultural, ethical, and legal factors affecting drug therapy, patient responses, and nursing practice.NURS 5041
IV.Course ObjectivesAt completion of this course students will be able to:Objective No.12ObjectivesDemonstrate knowledge of advanced pharmacologic principles commensurate forindependent practice.Discuss therapeutics of the drug classes covered in this course with consideration of theirmechanismsof action, cautions, contraindications, and rationale for use across the lifespan.Articulate concepts of pharmacogenomics and apply these to understand the variation in drugresponses in specific patient groups, for example, those differing by age, sex, race, geographicorigin.Identify appropriate pharmacotherapy approaches to common conditions encountered in theprimarycare setting with an emphasis on safety and appropriate patient and family education.Demonstrate advanced knowledge of specific adverse drug effects and prioritization ofapproaches to ADE management.3456Apply knowledge of pharmacodynamics and pharmacokinetics relevant to polypharmacyand drug- drug interactions.7Demonstrate use of professional technological resources on drug therapy consistent withan ongoing commitment to lifelong learning to support advanced practice.V.Course Format/Instructional MethodsThe format of the course will be online, using both asynchronous and synchronous approaches.Weekly topics listed in the course outline will be covered using before-class online review of majordrug classes relevant to the topic, online lectures, textbook and other readings, “thought” questions,online discussions, audio visual materials, case studies, and cour se handouts. Weekly problemsolving sets will be assigned to assist students in learning the material and its clinical applications.VI.Student Learning OutcomesStudent learning for this course relates to one or more of the following nine nursing core compe tencies:Nursing Core Competencies123456789Scientific Foundation CompetenciesLeadershipQualityPractice InquiryTechnology and Information LiteracyPolicyHealth Delivery SystemEthicsIndependent PracticeNURS 504*CourseObjective1, 2, 3, 4*2, 3, 4, 5****2, 3113, 6*Highlighted in this courseNURS 5042
The following table explains the highlighted competencies for this course, the related student learningoutcomes, and the method of assessment.SCIENTIFIC FOUNDATION COMPETENCIESCompetencies/Knowledge,Student Learning OutcomesMethod of AssessmentValues,SkillsCritically analyzes data andLMS posting and participationevidence for improving advancedin synchronous sessionsFamily Nurse Practitionernursing practice.Homeworkcompetent in ScientificExamFoundation Competencies:Integrates knowledge from theIntegrates scientific findings fromnursing, biopsychosocial fields,genetics, public health, qualityimprovement, and organizationalsciences for the continualimprovement of nursing care acrossdiverse settings.humanities and sciences withinthe context of nursing science.Translates research and other formsof knowledge to improve practiceprocesses and outcomes.Develops new practice approachesbased on the integration of research,theory, and practice knowledge.QUALITY udent Learning OutcomesUses best available evidence tocontinuously improve quality ofclinical practice.Family Nurse Practitionercompetent in QualityCompetencies:Discusses methods, tools,performance measures, andstandards related to quality, andapplies quality principles within anorganization.Method of AssessmentLMS posting and participationin synchronous sessionsExamsEvaluates the relationships amongaccess, cost, quality, and safety andtheir influence on health care.Evaluates how organizationalstructure, care processes, financing,marketing and policy decisionsimpact the quality of health care.Applies skills in peer review to promotea culture of excellence.Anticipates variations in practiceand is proactive in implementinginterventions to ensure quality.NURS 5043
TECHNOLOGY AND INFORMATION LITERACY COMPETENCIESCompetencies/Knowledge,Student Learning OutcomesMethod of AssessmentValues,SkillsIntegrates appropriate technologies forLMS posting and participationknowledge management toin synchronous sessionsimprove health care.HomeworkExamsFamily Nurse Practitionercompetent in Technology andInformation LiteracyCompetencies:Integrates and incorporatesadvances in technology within thepractice setting, resolves practiceproblems, works as a changeagent, and disseminates results.NURS 504Translates technical and scientifichealth information appropriate forvarious users’ needs. Assesses the patient’s andcaregiver’s educational needs toprovide effective, personalizedhealth care. Coaches the patient and caregiverfor positive behavioral change.Demonstrates information literacy skillsin complex decision making.Contributes to the design of clinicalinformation systems that promotesafe, quality and cost effectivecare.Uses technology systems that capturedata on variables for the evaluation ofnursing care.4
POLICY mily Nurse Practitionercompetent in PolicyCompetencies:Defends the ability of the advancedpractice nurse to intervene at thesystem level through the policydevelopment process and to employadvocacy strategies to influencehealth and health care.Student Learning OutcomesRecognize and manage personalvalues in a way that allowsprofessional values to guide practice.Method of AssessmentLMS posting and participationin synchronous sessionsExamsAdvocates for ethical policies thatpromote access, equity, quality, andcost.Analyzes ethical, legal, and socialfactors influencing policydevelopment.Contributes in the development ofhealth policy.Analyzes the implications of healthpolicy across disciplines.Evaluates the impact of globalizationon health care policy development.HEALTH DELIVERY SYSTEM COMPETENCIESCompetencies/Knowledge,Student Learning OutcomesMethod of AssessmentValues,SkillsApplies knowledge of organizationalLMS posting and participation inFamily Nurse Practitionerspractices and complex systems tosynchronous sessionscompetent in Health Deliveryimprove health care delivery.ExamsSystem Competencies:Explains how the advancedpractice nurse applies andintegrates broad, organizational,client centered, and culturallyappropriate concepts in theplanning, delivery, management,and evaluation of evidence-basedclinical prevention and populationcare and services to individuals,families, and aggregates/identifiedpopulations. As a member andleader of interprofessional healthcare system, the advanced practicenurse communicates, collaborates,and consults with other healthprofessionals tomanage and coordinate care.NURS 504Effects health care change using broadbased skills including negotiating,consensus building, andpartnering.Minimizes risk to patients and providersat the individual and systems level.Facilitates the development of healthcare systems that address the needs ofculturally diverse populations, providers,and other stakeholders.Evaluates the impact of health caredelivery on patients, providers, otherstakeholders, and the environment.Analyzes organizational structure,functions and resources to improvethe delivery of care.5
ETHICS mily Nurse Practitionercompetent in EthicsCompetencies: Includes matters involving moralprinciples and social policyincluding professional guidelinesfor advanced practice nursingwhen providing care.VII.Student Learning OutcomesIntegrates ethical principles in decisionmaking.Evaluates the ethical consequences ofdecisions.Method of AssessmentLMS posting and participationin synchronous sessionsHomeworkExamsApplies ethically sound solutionsto complex issues related toindividuals, populations andsystems of care.Course Assignments, Due Dates, and GradingAssignmentExam 1Exam 2Exam 3Exam 4HomeworkClass ParticipationDue DateWeek 4ExamOpens9/20/2019Week 7% of FinalGrade17.5%exam opens10/11/2019Week 11Examopens11/08/2019Week 0%10%Each of the major assignments is described below.Assignment: Exams (70% of course grade)Students will be given four online, objective closed-book exams during Weeks 5, 8, 12, and 15.These exams are intended to evaluate student performance in the course. Four noncumulativetests of equal weight will be given.Exam 1 will be based on content material from Weeks 1 through 4. Exam 2 will be based oncontent from Weeks 5-7. Exam 3 will be based on content from Weeks 8-11, and Exam 4 will coverthe content from Weeks 12-14.Exam Policies: Students are expected to take all examinations as scheduled in the ContentOutline. Exams are password protected in 2NUSC; they will be provided via a wall post on the LMSor via email from your section instructor. The exam may be opened and started at 12:00 noonPacific Time. Students will have 72 hours to complete the exam, which must be completed the firstNURS 5046
time it is opened. The exam clock will be set for 75 minutes. Requests to take an exam on a daydifferent from the stated date will only be granted for serious situations and must be approved bythe instructor.All exams in this course will require students to deploy a software called Proctortrack. This is asoftware system that automatically proctors student exams, verifies student identities throughoutthe exam, and provides instructors with brief video clips and screenshots if potential testingviolations occur. Proctortrack is fully integrated with the Learning Management System, however,students are required to complete a practice exam at the start of the semester to ensure thetechnology is setup properly on their computers. If students experience issues or have questionswith the practice exam or with Proctortrack in general, students should contact student support forhelp in advance of taking the exam.To ensure a successful testing environment, students should: Choose a private location with no distractions Have nothing around that could make noise Set up proper lighting and ensure his/her face is clearly visible Not have food or drink Close all browser tabs and other programs Have only one keyboard, mouse, and monitor connected Not leave testing area/camera view during the exam Not take or use notes (unless specifically allowed by instructor) Not use or have nearby additional technology (phones, tablets, television, etc.) Not have other people in the room Have a hardwire connection Not write or take notes during the exam If disruption in the examination occurs for any reasons student must call tech support toreport concern and notify the section instructor.This assignment relates to Student Learning Outcomes 1, 3, 5, 6, 7, and 8.Assignment: Homework (20% of course grade)Assigned homework must be completed and uploaded before the start of synchronous sessioneach week, beginning with Week 3. Students are expected to complete and upload theirdocument within the timeframe set by the section instructor (refer to assignment section on theLMS for specific homework instructions and timelines). Homework is to be edited for correctgrammar and spelling; any references should be cited using APA format, and directquotations must be indicated in appropriate APA format. It is expected that students will watchALL asynchronous materials, and complete ALL online questions from the module beforeattempting the homework.Homework grades will be based on:1.2.3.4.Use of correct terminologyQuality of writingFactual accuracyEvidence of careful engagement with asynchronous materials and therecommended text book5. Accurate and eligible prescriptionNURS 5047
Due: Weekly (prior to Live Session)This assignment relates to Student Outcomes 1, 3, 5, 6, 7, and 8.Assignment: Class participation (10% of course grade)Class participation will recognize student asynchronous preparation for live session, evidence o fcomprehension of the material, and the ability to communicate knowledge with peers. Classparticipation is evidenced by completion of asynchronous exercise questions, verbal and chat podcontributions during synchronous sessions AND in the weekly question wall. Grading for classparticipation is based on the rubric for preparation and participation (posted in Course Tools).Posting a weekly wall question 24 hours prior to asynchronous class and responding to a fellowstudent’s question is included in the participation component of this course.Due: Weekly (prior to live session)This assignment relates to Student Learning Outcomes 1, 3, 5, 6, 7, and 8.Note: Faculty reserve the right to modify content and/or date for assignments and/orexams. In some cases, depending on national and University holidays, live session daysand times may be adjusted. Notice of such changes will be given at the start of thesemester to permit students to arrange their work schedules accordingly.Class grades will be based on the following:ClassGrades3.85–4.00 A3.60–3.84 A3.25–3.59 B 2.90–3.24 B2.60–2.89 B2.25–2.59 C 1.90–2.24 CFinal –7670–72AAB BBC CC-Within the School of Social Work, grades are determined in each class based on the following standards,which have been established by the faculty of the School: (1) Grades of A or A- are reserved for studentwork which not only demonstrates very good mastery of content but which also shows that the studenthas undertaken a complex task, has applied critical- thinking skills to the assignment, and/or hasdemonstrated creativity in her or his approach to the assignment. The difference between these twogrades would be determined by the degree to which these skills have been demonstrated by the student.(2) A grade of B will be given to work which is judged to be very good. This grade denotes that astudent has demonstrated a more-than-competent understanding of the material being tested in theassignment. (3) A grade of B will be given to student work which meets the basic requirements of theassignment. It denotes that the student has done adequate work on the assignment and meets basiccourse expectations. (4) A grade of B- will denote that a student’s performance was less than adequateon an assignment, reflecting only moderate grasp of content and/or expectations. (5) A grade of C wouldreflect a minimal grasp of the assignments, poor organization of ideas and/or several significant areasNURS 5048
requiring improvement. (6) Grades between C- and F will be applied to denote a failure to meet minimumstandards, reflecting serious deficiencies in all aspects of a student’s performance on the assignment.NURS 5049
VIII.Required and Supplementary Instructional Materials and ResourcesRequired Textbook:Arcangelo, V.A., Peterson, A.M., Wilbur, V., & Reinhold, J.A. (2017). Pharmacotherapeuticsfor Advanced Practice: A Practical Approach (4th ed.). Philadelphia, PA: WoltersKluwer.Textbook readings will be supplemented by additional resources as appropriate;representative resources are listed in the weekly outline below. Student questions from thereadings will be posted in an online forum for responses, comments, and follow-up questionsfrom the whole class, as indicated in the class participation note s.Recommended Guidebook for APA Formatting:American Psychological Association. (2009). Publication manual of the AmericanPsychological Association (6th ed.). Washington, D.C.: American PsychologicalAssociation.Recommended Textbooks/Websites:Whalen, K. (2015). Lippincott Illustrated Reviews: Pharmacology (6th ed.). Philadelphia, PA:Wolters Kluwer.Woo, T.M. & Wynne, A.L. (2011). Pharmacotherapeutics for Nurse Practitioner Prescribers(3rd ed.). Philadelphia, PA: FA Davis Co.Note: Additional required and recommended readi10ngs may be assigned by the instructorthroughout the course.NURS 50410
WeekContent1Module 1: Introduction to Pharmacology This module covers an introduction to the course including courseexpectations. The topics of pharmacodynamics, pharmacokineticsand pharmacogenomics will be discussed. The major principles ofpharmacology across the lifespan will be reviewed.2Module 2: Advanced Principles of Pharmacology This module provides a foundation for prescriptive practice. Theart and science of prescribing will be discussed. This modulefocuses on prescribing considerations and a review of drugsafety.3Module 3: Central Nervous System Drugs, Part 1 This module provides an overview of neurotransmission. A reviewof drugs used for ADHD, dementia, epilepsy, and Parkinson’sdisease is covered in this module. Exemplar medications providedfor these topics include amphetamines, donepezil, phenytoin,levetiracetam, valproic acid, and carbidopa.4Module 4: Central Nervous System Drugs, Part 2 This module provides a review of mood-stabilizing drugs,antianxiety drugs, and antipsychotic drugs. Exemplarmedications provided for these topics include fluoxetine,citalopram, nortriptyline, lithium, alprazolam, and zolpidem.AssignmentsHomeworkHomeworkExam 1 (M1-4)Opens09/20/19 at 12pm PSTCloses09/22/19 at 12pm PST5Module 5: Management of Pain and Inflammation This module provides an overview of the concept of painphysiology. The module includes a review of opioid peptides,opiate drugs, anti- inflammatory drugs. Medications used forgout, management of headaches/migraines, atypical painsyndromes will be reviewed. Exemplar medications provided forthese topics include morphine, oxycodone, tramadol, NSAIDs,prednisone, etanercept, allopurinol, colchicine, gabapentin, andImitrex.Homework6Module 6: Anti-infective Agents, Part 1 This module provides an overview of the principles ofantibacterial therapy. Agents that target the cell wall and agentsthat target bacterial protein synthesis will be discussed. A reviewof other antibacterial drugs will be included. Systemic vs. localadministration will be discussed. Exemplar medications providedfor these topics include penicillin, amoxicillin/clavulanate,ceftriaxone, doxycycline, azithromycin, clindamycin,trimethoprim/sulfamethoxazole, nitrofurantoin, ciprofloxacin, andmetronidazole.HomeworkNURS 50411
7Module 7: Anti-infective Agents, Part 2 This module provides a review of medications used in thetreatment of mycobacteria, fungi, viruses and parasites. Patternsof infection and mechanisms of drug therapies will be reviewed.Exemplar medications provided for these topics include isoniazid,rifampin, clotrimazole, fluconazole, acyclovir, emtricitabine,tenofovir, nevirapine, and oseltamivir.HomeworkExam 2 (M5-7)Opens:October 11 12pm PSTCloses:October 14 12pm PST8Module 8: Respirator
Pharmacology for Advanced Nursing Practice 3 Units In modern pharmacology, it’s so clear that even if you have a fixed dose of a drug, the individuals respond very differently to one and the same dose. —Arvid Carlsson, Nobel Prize in Physiology of Medicine 2000 I. Course Prerequisites or Corequisites
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