FCC LECTURE EXAM [#1] - Sinoe Medical Association

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[#1] FCC LECTURE EXAM Name: Group: Grade: 3/When a blood vessel is severed, the % damaged epithelial tissue that lines the vessel would be a. mesothelium b. simple columnar c. endothelium d. simple cuboid 4/Ciliated epithelium that is destroyed by disease would cause malfunction of which body system? a. digestive b. respiratory c. skeletal d. circulatory Total 70 questions: 50 multiple choice, matching 10 open questions 10 picture questions Multiple choice 1/ The space between the pleurae of the lungs that 5/Which statement about enzymes is false? A) Enzymes raise the activation energy needed to start a reaction. B) Enzymes are composed mostly of protein. C) Enzymes are organic catalysts. D) Enzymes may be damaged by high temperature. Answer: A extends from the sternum to the vertebral column is the a. cranium b. mediastinum c. pericardial cavity d. thorax 2/. Which of the following statements is true of connective tissue? A) Elastin fibers are sometimes called white fibers. B) When connective tissue is stretched, collagen gives it the ability to snap back. C) Collagen fibers provide high tensile strength. D) Reticular fibers form thick, ropelike structures. Answer: C d. coronal 6/Choose the answer that best describes HCO3-. A) a bicarbonate ion B) common in the liver C) a weak acid D) a proton donor Answer: A 7/ is fat soluble, produced in the skin on exposure to UV radiation, and necessary for normal bone growth and function. A) Vitamin K B) Cortisol C) Vitamin A D) Vitamin D Answer: D 8/Which of the following is not an electrolyte? A) HCl B) Ca2CO3 C) H2O D) NaOH

FCC LECTURE EXAM [#1] Answer: C 9/Sucrose is a . A) monosaccharide B) disaccharide C) polysaccharide D) triglyceride Answer: B 10/In order for the DNA molecule to get "short and fat" to become a chromosome, it must first wrap around small molecules called . a/ histones b/histamines c/phosphate d/thymine e/uracil c) The maintenance of the potential is based exclusively on diffusion processes. d) When the sodium-potassium pump is activated, potassium is pumped into the cell twice as fast as the sodium is pumped out, thus causing the membrane potentia 14/A surgical pathology specimen from a 24-yearold woman seen at a reproductive medicine clinic demonstrates a ciliated columnar epithelium. From which of the following locations in the female genital tract was the biopsy obtained? a) b) c) d) Cervix Endometrium Fallopian tube Ovary 11/Some hormones enter cells via . A) exocytosis B) endocytosis C) pinocytosis D) receptor-mediated endocytosis Answer: D 12/Why are free radicals so dangerous to cells, and how are they dealt with by the body? a/ Free radicals are highly reactive chemicals that cause havoc in any cellular environment by reacting with things they should not. Cells with peroxisomes have enzymes specific to reducing free radicals into less reactive chemicals. b/ Free radicals are highly reactive chemicals that cause havoc in any cellular environment by reacting with things they should not. c/ Cells with peroxisomes have enzymes specific to reducing free radicals into less reactive chemicals. d/ Cells with lysosomes have enzymes specific to increase free radicals into less reactive chemicals. 13/Which of the following is true regarding the generation of a membrane potential? a) Both potassium and sodium ions can "leak" through the cell membrane due to diffusion b) In the polarized state, sodium and potassium ion concentrations are in static equilibrium 15/ An epithelial membrane . A) usually involves transitional epithelium B) is formed of epithelium and smooth muscle C) contains simple or stratified epithelia and a basement membrane D) never contains mucus-forming cells Answer: C 16/The drug Procaine (also known as Novocaine) blocks sodium (Na ) channels in plasma membranes. Given this information, which one of the following statements is most likely true about a cell bathed in a solution that contains Procaine? a. There will be no osmosis across the cell’s plasma membrane. b. Na will diffuse directly across the lipid bilayer. c. Na will be unable to cross the membrane by facilitated diffusion. d. Mitochondria will not be able to generate ATP. e. Na will diffuse from a low concentration to a high concentration. 17/Transcytosis is . A. combining an endosome with a lysosome and degrading or releasing the contents B. transporting an endosome from one side of a cell to the other and releasing the contents by exocytosis

FCC LECTURE EXAM [#1] C. recycling the contents of the endosome back to the surface of the cell 22/ A 35 year old female is suffering GERD [GastroEntero D. storing the contents of the endosome reflux disease] for the past 15 years, despite medical treatment the reflux are getting worst. A Nissa fundoduplicature surgery was proposed many years ago, to fix her esogatric sphincter but afraid of the outcome and 18/The RNA responsible for bringing the amino acids to complication she refuses the idea of any surgery. the "factory" site for protein formation is the . The patient did not have a gastrofibroscopy for over 6 A. rRNA years, but this year with the insistance of her GI doctor she B. mRNA did one. Where biopsies of the gastroesophageal junction C. tRNA were performed, showing a glandular tissue instead of a D. ssRNA non keratinized stratified squamous epithelium. What happened to this epithelium? 19/Cell junctions that promote the coordinated activity of cells by physically binding them together into a cell community include all of the following except A. gap junctions B. desmosomes C. peroxisomes D. tight junctions 20/Which of the following types of connective tissue exhibits these characteristics: Copious amount of blood vessels Dominated by large empty looking cells with thin margins and considerable amounts of stored lipids Often pale Performs cushioning functions for the kidneys and the posterior portions of the eyes. a/. Areolar b/. Dense regular connective tissue c/. Dense irregular connective tissue d/. Adipose tissue e/. Reticular tissue 21/ Which of the following modes of exocrine secretion is secretion by rupturing? a/. Merocrine b/. Apocrine c/. Holocrine d/. Endocrine a/ picnosis b/metaplasia c/anaplasia d/superplasia e/ I think you are nuts asking this type of questions

FCC LECTURE EXAM [#1] Match the following: A) Serous membrane B) Endothelium C) Mucous membrane D) Cutaneous 23) The epithelial membrane that lines the closed ventral cavities of the body. Diff: 1 Page Ref: 138 24) The epithelial membrane that lines body cavities open to the exterior. membrane Diff: 1 Page Ref: 138 25) Consists of keratinized stratified squamous epithelium. Diff: 2 Page Ref: 138 26) Found lining the digestive and respiratory tracts. Diff: 2 Page Ref: 138 27) Makes up the pleura and pericardium. Diff: 2 Page Ref: 138 28) Lines blood vessels and the heart. Diff: 1 Page Ref: 117 Answers: 11) A 12) C 13) D 14) C 15) A 16) B Match the following: A) Nucleus B) Nucleoli C) Microtubules D) Endoplasmic reticulum E) Ribosomes 29) Plays a role in the synthesis of steroid-based hormones and proteins. Diff: 2 Page Ref: 84-85; Table 3.3 30) The actual site of protein synthesis. Diff: 1 Page Ref: 84; Table 3.3 31) Hollow cytoskeletal elements that act as organizers for the cytoskeleton. Diff: 2 Page Ref: 88; Table 3.3 32) Dense spherical bodies in the nucleus that are the synthesis site for ribosomal RNA. Diff: 1 Page Ref: 93; Table 3.3 33) Houses DNA and RNA. Diff: 1 Page Ref: 91-92; Table 3.3 Answers: 26) D 27) E 28) C 29) B 30) A 4 P ag e .34/Nonpolar region of phospholipid. Answer: C 35/Glycocalyx. Answer: A 36/Polar region of phospholipid. Answer: B 37/Peripheral protein. Answer: E 38/Integral protein. Answer: D 39/Identification "tags" for the cell. Answer: A 40/Receptors for signal transducers. Answer: D 41/Hydrophilic portion. Answer: B Match the following: A) Tight junctions B) Desmosomes C) Gap junctions 42) Help prevent molecules from passing through the extracellular space between adjacent cells. Diff: 1 Page Ref: 66 43) Type of anchoring junction. Diff: 1 Page Ref: 66-67 44) Communicating junction. Diff: 1 Page Ref: 67 45) Present in electrically excitable tissues. Diff: 1 Page Ref: 67 46) Abundant in tissues subjected to great mechanical stress. Diff: 2 Page Ref: 66-67 Answers: 31) A 32) B 33) C 34) C 35) B 47/ A 45-year-old woman is admitted to the hospital for surgical removal of a tumor on her thyroid gland. The surgeon informs her that she will have only a very small scar. How could this

FCC LECTURE EXAM [#1] be possible? a/ By making a thin incision, the amount of granulation (scar-forming) tissue will be minimal. As the scar tissue beneath matures and contracts, the layer of epithelium thickens and resembles the adjacent tissue. The final result may be only a fine white line. b/By making a large incision, the amount of granulation (scar-forming) tissue will be minimal. As the scar tissue beneath matures and contracts, the layer of epithelium thickens and resembles the adjacent tissue. The final result may be only a fine white line. c/ By making a large incision, the amount of granulation (scar-forming) tissue will be none. As the scar tissue beneath matures and contracts, the layer of epithelium thickens and resembles the adjacent tissue. The final result may be only a fine white line. 48/ Stool normally contains a small amount of mucus, but passing stools with visible amounts of mucus can be from a variety of causes. Mucus in the stool is a common symptom of irritable bowel syndrome (IBS) and ulcerative colitis (UC), and is seen to a lesser degree in Crohn's disease (CD). A bacterial infection, anal fissure, or a bowel obstruction may also cause the passage of mucus: What cells will secrete the extra mucus seen in these condition caused by irritation and inflammation: a/mucus cell b/goblets cells c/parietal cell d/zymogenic cells e/glial cells 49/ what structure the above picture represent” a/ duct compound b/ duct simple c/ simple tubular d/ papillary 5 P ag e 50/ A 120 kg patient is evaluated for his total amount of water in his total system, to help him establishing a a plan of diet including the amount of fluid needed daily for ingestion.His lab shows a Na at 135 meq/l, potassium 3 meq/l , creatinine 2. What amount of total body water this patient is composed of, and what is his ECF volume [extra cellular fluid ]. a/72L of Total Body Water,135 ECF b/ 120L of Total Body Water,135 ECF c/72L of Total Body Water,3 ECF d/60L of Total Body Water,2 ECF e/ need to do some calculation, and do not have that much time left. 51/Fluid regulation depends on : a/the sensing of the osmolality, or solute concentration, of the blood. b/ Fluid regulation depends on the sensing of the oncotic pressure, or solute concentration, of the blood. c/ Fluid regulation depends on the sensing of the temperature and IL4 d/ Fluid regulation depends on drinking water, kidney vessels, salts , erythropoeitin 52/Which of the following is TRUE? a. The number of negative feedback systems in the body is much less than the number of positive feedback systems in the body b. Positive feedback is ALWAYS detrimental to one's health c. Maintenance of blood glucose concentration at homeostatic levels (90mg/100ml) is an example of a negative feedback loop. d. Positive feedback is NEVER detrimental to one's health e. A and C are both TRUE

FCC LECTURE EXAM [#1] Integumental system: 51/ Which of the following is NOT a component of the epidermis of thin skin? What do these cell produce?[these cells are not to be confused with smooth muscle cells] a/ reticuline, collagen, elastin b/estrogen, progesterone c/insulin or glucagon d/ all of the above Which of the following are examples of extracellular fluid? I. Lymph II. Blood III. Cerebrospinal fluid Iv Intraocular fluid a. b. c. d. e. I,II, and III only I, II, and IV only I and II only I,II, III, and IV II, III, and IV only Which of the following is an example of NEITHER muscle nor connective tissue? a. Bone b. Cardiac muscle within the atrium of the heart c. Blood d. Hyaline cartilage e. None of the above In which of the following might you expect to find all of the following: 1. Nonkeratinized stratified squamous epithelium 2. Simple columnar epithelium 3. Simple columnar epithelium with goblet cells 4. Simple columnar epithelium with microvilli 5. NO pseudostratified columnar epithelium a. b. c. d. e. 6 P ag e Glomerular capsule Digestive Tract Respiratory tract Sebaceous gland duct Exterior body surface a. Melanosomes b. Keratinized cells c. Capillaries d. Keratin e. All of the above 52/ Keratohyalin granules are most apparent in which of the following layers of the epidermis? a. Stratum basale b. Stratum spinosum c. Stratum granulosum d. Stratum lucidum 53/ the base of its production is cholesterol, very important for our everyday life, although too much of it can hurt. A) Vitamin K B) Cortisol C) Vitamin A D) Vitamin D Answer: b 54/ Which of the following cells has been implicated in playing a role in immunological reactions in the skin? a. Melanocyte b. Capillary epithelial cell c. Langerhans cell d. Hair follicle cell 55/ A new miracle skin cream recently hit the beauty counters which is suppose to stimulate collagen production. Which cell is it supposedly stimulating? a. Langerhans cell b. Keratinocyte c. Melanocyte

FCC LECTURE EXAM [#1] d. Merkel cell e. Fibroblast Diff: 1 Page Ref: 150, 152 Answers: 8) D 9) A 10) B 11) E 12) C 56/ Epidermis what below answers might be correct: a. The epidermis lacks blood vessels. b. The deepest layer of the epidermis is called the stratum basale. c. The stratum basale is nourished by blood vessels in the dermis. d. Cells of the stratum basale can divide and grow because they are nourished so well. e. 67If a splinter penetrated the skin into the second epidermal layer of the sole of the foot, which cells would be damaged? A) granulosum B) basale C) lucidum D) spinosum Answer: C All of the above are correct Match the following: A) Erythemia B) Jaundice C) Addison’s disease D) Pallor E) Cyanosis 57) May indicate embarrassment, fever, hypertension, inflammation, or allergy. Diff: 2 Page Ref: 155 58) May indicate fear, anger, anemia, or low blood pressure. Diff: 2 Page Ref: 155 59) Usually indicates a liver disorder. Diff: 2 Page Ref: 155 60) Appearance of a permanent tan; bronzing. Diff: 2 Page Ref: 155 61) A bluish color in light-skinned individuals. Diff: 2 Page Ref: 155 Answers: 17) A 18) D 19) B 20) C 21) E A) Keratin B) Merkel disc C) Cornified keratinocytes D) Keratinocytes E) Epidermal dendritic cells 62) The most abundant cells of the epidermis. Diff: 1 Page Ref: 150 63) The protein found in the epidermis that is responsible for toughening the skin. Diff: 1 Page Ref: 150, 152 64) Cells plus a disc-like sensory nerve ending that functions as a sensory receptor for touch. Diff: 1 Page Ref: 150 65) Skin macrophages that help activate the immune system. Diff: 1 Page Ref: 150 66) Cell remnants of the stratum corneum. 7 P ag e 68/Which of the following cutaneous receptors is specialized for the reception of touch or light pressure? A) Meissner's corpuscles B) Pacinian corpuscles C) free nerve endings D) Krause's end bulbs Answer: A 69/The gland is a modified sudoriferous gland that secretes wax. A) eccrine B) apocrine C) ceruminous D) mammary Answer: C 70/Despite its apparent durability, the dermis is subject to tearing. How might a person know that the dermis has been stretched and/or torn? A) The pain is acute due to the large number of Meissner's corpuscles. B) The appearance of visible, silvery-white scars is an indication of stretching of the dermis. C) The blood vessels in the dermis rupture and the blood passes through the tissue, causing "black-and-blue marks." D) The stretching causes the tension lines to disappear. Answer: B 71/Burns are devastating and debilitating because of loss of fluids and electrolytes from the body. How do physicians estimate the extent of burn damage associated with such dangerous fluid loss? A) by measuring urinary output and fluid intake B) by observing the tissues that are usually moist C) through blood analysis D) by using the "rule of nines" Answer: D 72/Balding men have tried all kinds of remedies, including hair transplants, to restore their lost locks. Explain the cause of male pattern baldness.

FCC LECTURE EXAM [#1] a/ It appears to be genetically determined and sexlinked, and is possibly caused by a delayed-action gene that responds to DHT and alters normal metabolism. b/ It appears to be genetically determined and sex-linked c/ It appears not to be genetically determined and sexlinked, and is possibly caused by a non delayed-action gene that responds to DHT and alters normal metabolism. d/all of the above are correct answer e/don’t know I am bold tried everything, did not work 73/ Billions of consumer dollars are spent for deodorants and antiperspirants each year. Explain the production of body odors frequently associated with axillary skin. a/ Sweat is mostly an odor watery secretion produced by holocrine and apocrine glands. The odor usually arises due to the metabolic activities of bacteria on the surface of the skin. b/Sweat is mostly an odorless watery secretion produced by eccrine and apocrine glands. . c/Sweat is mostly an odorless watery secretion produced by eccrine and apocrine glands. The odor usually arises due to the metabolic activities of bacteria on the surface of the skin. spot contains shades of black, brown, tan, and sometimes blues and reds; and diameter the spot is larger than 6 mm in diameter. It is imperative that Mary have a physician examine the spot immediately. Any unusual lesion on the skin of a sun worshipper should be examined b/ The ABC rule refers to the following: asymmetry where the two sides of the spot do not match; border irregularity the borders are not round and smooth; color the pigmented spot contains shades of black, brown, tan, and sometimes blues and reds; and diameter the spot is larger than 6 mm in diameter. It is imperative that Mary have a physician examine the spot immediately. Any unusual lesion on the skin of a sun worshipper should be examined c/ The ABCD rule refers to the following: symmetry where the two sides of the spot do not match; border regularity the borders are not round and smooth; color the pigmented spot contains shades of pink, white, tan, and sometimes blues and reds; and depth the spot is larger than 6 mm in diameter. It is imperative that Mary have a physician examine the spot immediately. Any unusual lesion on the skin of a sun worshipper should be examined d/ I am not a doctor but I think everything is fine with her and no further step need to be taken. d/ Sweat is mostly an odorless watery secretion produced by eccrine and holocrine glands. The odor usually arises due to the aerobic activities of virus on the surface of the skin. 75/ Explain why soap that has an alkaline base may not be healthy for some patients to use daily. e/ what are you talking about? a// The skin's basic mantle retards growth of bacteria. Soap may destroy the basic mantle of the skin, causing it to gain its protective mechanism. Some soaps contain antibacterial agents, which can change the natural flora of the skin. 74/ Mary noticed a large, brown spot on her skin. She has been playing tennis in the sun for several years without sun protection. She reported the discovery to a friend, who told her to apply the ABCD rule to determine whether or not she had malignant melanoma. Her friend told her that if her answer was "no" to the questions that were asked by the ABCD rule, she had nothing to worry about. What is the ABCD rule and should she ignore the spot if her answers are negative? a/ The ABCD rule refers to the following: asymmetry where the two sides of the spot do not match; border irregularity the borders are not round and smooth; color the pigmented 8 P ag e b/ The skin's acid mantle retards growth of bacteria. Soap may destroy the acid mantle of the skin, causing it to lose its protective mechanism. Some soaps contain antibacterial agents, which can change the natural flora of the skin. c/ The skin's acid mantle retards growth of bacteria. d// Some soaps contain antibacterial agents, which do not change the natural flora of the skin.

FCC LECTURE EXAM [#1] Open question INTERSTITIAL FLUID ISF 2/3 EXTRACELLULAR FLUID Total blood volume plasma 1/ Epithelial Tissue functions? [extracellular volume] and the cellular -Protection mechanical dehydration chemicals (acids) enzymes pathogens -Absorption Nutrients Gasses Ions (salt) -Secretion Mucus enzymes/proteins lipds/steroid hormones salts water (sweat) nutrients (male/femal reproductive). -Sensation -Contraction (myoepithelial cells) -Transport elements of blood [red cells [intracellular 2/Briefly name the subphases of interphase and tell what they do G1 - growth phase. The cell is metabolically active and the centriole begins to divide at the end of this phase. S - DNA replicates itself. New histones are made and assembled into chromatin. G2 - Enzymes and proteins are synthesized and centriole replication is completed. This is the final phase of interphase 3/Name some membranous organelles [3]: – -Mitochondria, peroxisomes, lysosomes, endoplasmic reticulum, and Golgi apparatus 4/A med students found a slide on his microscope, the slide show a multiple layer epithelium with the apical layer looking like a dome. What type of epithelium are we dealing with in this case: a/transitional epithelium fluid] 6/ The three interdependent components of control mechanisms: Receptor – monitors the environments and responds to changes (stimuli) Control center – determines the set point at which the variable is maintained Effector – provides the means to respond to stimuli 7/List at least 7 characteristics of life. - MOVEMMENTchanges of either the entire organism or a part of the organism, externally from place to place and/or internally, such as in peristalsis. Responsiveness refers to the ability of an organism to detect changes either within itself or the environment surrounding it and then react to these changes. Growth generally refers to an increase in body size without important changes to its general shape. Reproduction is the process of making a new organism, as in parents producing offspring. It also discusses the process whereby cells can produce others like themselves to take the place of damaged or destroyed cells. Respiration refers to the process of obtaining oxygen, using the obtained oxygen in release of energy from foods, and removing waste gases that are produced in the process. Digestion is the chemical change of ingested foods into simpler substances that can be taken in and used by body parts. Absorption is the passage of digested substances through membranes 8/Name some Connective Tissue Cells [5]: 5/Fluid within the body composition: Intracellular fluid ICF 2/3 BODY WATER EXTRACELLULAR FLUID ECF 1/3 BODY WATER 9 P ag e -

FCC LECTURE EXAM [#1] Stratum lucidum—this layer appears between the stratum granulosum and stratum corneum in the thickened skin of the palms 9/ Aunt Jessie woke up one morning with excruciating pain in her chest. She had trouble breathing for several weeks. Following a visit to the doctor, she was told she had pleurisy. What is this condition and what did it affect? Answer: Pleurisy is an inflammation of the pleura, the serosal membranes covering the lungs and lining the thoracic wall. Pain is caused by the irritation and friction as the lungs rub against the walls of the cavity. 10/ John, a 72-year-old grandfather, had been smoking heavily for 24 years and had a persistent cough. A biopsy of his lung tissue revealed considerable amounts of carbon particles. How could this happen considering the natural cleaning mechanism of the respiratory system? Answer: The sweeping action of the ciliated epithelium is essential in order to propel inhaled dust and other debris out of the respiratory tract. Anything that inhibits this mechanism would allow foreign substances to remain in the tract, which may cause damage. Chemicals such as nicotine may inhibit the action of the cilia, allowing carbon particles found in smoke to remain in the lungs. List functions of skin. a. A protective covering b. Aids in body temperature regulation c. Retards water loss d. Houses sensory receptors e. Synthesizes various chemicals f. Secretes small quantities of waste substances 63. List the layers of the epidermis. The layers in the epidermis are: Stratum basale—the deepest layer Stratum spinosum—a relatively thick layer Stratum granulosum—a granular layer Stratum corneum—a fully keratinized layer 10 P a g e Lecture pictures: -----------------------------Bonus question: -----------------------------------------

FCC LECTURE EXAM It is tooo easy 11 P a g e [#1]

.34/Nonpolar region of phospholipid. Answer: C 35/Glycocalyx. Answer: A 36/Polar region of phospholipid. Answer: B 37/Peripheral protein. Answer: E 38/Integral protein. Answer: D 39/Identification "tags" for the cell. Answer: A 40/Receptors for signal transducers. Answer: D 41/Hydrophilic portion. Answer: B Match the following:

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