Int J Ayu Pharm Chem

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Int J Ayu Pharm ChemREVIEW ARTICLEwww.ijapc.come-ISSN 2350-0204Role of SwarnaPrashan to Boost Immunity in ChildrenDivya1*, Deepshikha2, Utkarsh Gupta3 and G.P.Garg41-4Dept.of Kaumarbhritya, UAU, Gurukul Campus, Haridwar, Uttarakhand, IndiaABSTRACTSwarna Prashan Sanskar mentioned under shodash sanskar is an ancient ritual. SwarnaPrashanameans to administer Swarna (gold) in liquid form along with honey, ghee and some herbalmedicines. It improves the intellectual power and enhances the non-specific immunity of thebody. Materials and Methods-Many databases including research articles from Pub med, JAIM, research gate, ayurvedic text books were considered with the key words like ‘SwarnaPrashan Sanskar’, ‘Sanskar’, ‘Immunity’, ‘Immunization’. Results-In Swarna Prashan we useSwarna bhasma which is in form of nano particle which is easily absorb by small intestine andwould reach the target site of action through blood. Several studies show Swarna bhasmashowed no toxicity as judged by SGOT, SGPT, Serum creatinine and Serum urea level andhistological studies. Gold ash is also effective in motor neuron disease in small doses. Gold isa good immunostimulant and also stimulate phagocytic index of macrophages. Swarna bhasmaalso prevents free radical injury to tissues and have nootropic, antiacetylcholinesterase,analgesic and antistress activity. Honey has an inhibitory effect to many bacteria and alsodevelops resistance against allergens remaining unaffected by them. Ghee has Omega 6 andOmega 3 fatty acid that is good for neurological and brain development. ConclusionAccording to Ayurvedic literature it would possess properties like madhura, rejuvenate,immunity booster, improves complexion and growth of the body, accelerate growth of the brainand improves memory, also increase digestion power of the body.KEYWORDSSwarna, Prashan, ImmunityGreentree Group PublishersReceived 25/12/19 Accepted 08/02/19 Published 10/03/19Divya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com157

INTRODUCTIONVaccinesSanskar are performed for the physical,immunity means immunity to a particularsocial, and religious development. Thediseases,word Sanskar is derived from root wordproduces non-specific immunity means it‘Kri’ with ‘Sam’ upsarga, which is beingactivates non specific immune cell thatused for several meanings for example inrespond to various antigen and protect thesenseabody from various diseases. It is a mostpurifacatory sacrament or ceremony tochallenging question for parents and to theenhance the qualities. In Ayurveda, thegovernment too, how to preserve uiredSwarnaPrashanhienhance the physical, mental health andGunaantradhyanum” means incorporatingimmunity of children where they suffersthe specific qualities (in various dravyas orfrom adverse effect of modern medicines,medicines as rasa aushadhi)1.improper life style, excessive intake of junkIn hindu dhrama granthas about 16-40foods and preservative foods, and exposuresanskar are described, but in practice 16of electronic distraction. In Ayurvedawordsanskaris“SanskaraoJatakarmaSwarna Prashana Sanskar is in practice forSanskar is the first sanskar, which ismore than of 1000 years. It enhances thedescribed by Acharya Charaka. In Jataphysical and mental health of childrenkarma sanskar honey mixed with gheewithout any side effects. Now a days,shouldbornswarna prashan sanskar is promoted bychild3.OtherAcharyas said that it can bemany ayurvedic practitioner and by themixed with Swarna also& it boost thegovernment of few states. In many places inimmunity of children many folds.India swarna prashan sanskar is termed asFrom ancient time, Swarna Prashan hasSwarna Amrita Prashana, Swarna Bindubeen effectively done for boosting thePrashana4.immunity of neonate, which has beenAIMlargely replacedTo study benefits of Suvarna ly vaccines.Immunity means capacity of body to limitSanskar in details.the spread of infection and decrease theintensity of disease. In ayurved immunityMATERIALS & METHODScan be correlated with vyadhikshamtava.Many databases including research articles,Pub med, J-AIM, Research Gate, , AyurvedDivya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com158

research data base (6th edition from 2001-he can remember all things whatever he2014 thesis included), ayurvedic, variouslisten5.modern2. Acharya Vagbhatt described gold lickingtextbooksandAPIwereconsidered reviewed with the key wordsis as follows6-like Swarna Prashan Sanskar, Sanskar,Paste of aindri, brahmi, shankhpushpi andintellectualvacha ,one harenu in quantity, mixed withperformance,immunity,immunization.honey and ghee, sanctified by touching withSWARNA PRASHAN IN AYURVED-tip of kusa grass with sacred hymns andAcharya Kashyapa described the Swarnaheld in a plate resembling in asvattha leaf,Prashana vidhi in detail with its benefits.made of gold, should be given to the childAs per Aacharya Kashyap, In Swarnato lick to promote intelligence, long life andPrashan Swarn is rubbed on a washed stonestrength.with honey, ghee and water and then while3. Four formulation of Swarna arekeeping the baby′s face towards East Swarndescribed by Acharya Sushruta whichis given to child for licking. The benefits ofenhances intellectual power and overallthis Sanskar is-growth of baby. These are mbination of Swarna which are ाग्निबलवधणनम्। ��मासात परममेधावी व्याग्नधग्निनण च दृश्यते।षड् ��ा, सूत्रस्थानम् )meansimprovement in intelligency, digestivepower, and strength of body, Ayushyameans improvement in life span, Mangalyameans auspicious, Punya means sacred,Vrishya means aphrodisiac, Grahapahammeans relieves all bad effects of grahas. IfSwarnaPrashan administer to child for onechildbecomes Kustha, Vacha, Brahmi, honey andGhrita paste of Bhrami and -Parammedhavimeans Genious and if administering for six Arkapushpa, Vacha with Ghrita andhoney. Kaidarya and Shwet Durva withGhrita7.Dosage-Theaccuratedoseofswarnaprashan is not described by anyacharyas in literature, but by calculation ofdose of swarna bhasm we can calculateoverall dose of swarnaprashan. Referencesfrom the various text which are listed –months, child becomes Shruta Dhara meansDivya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com159

1/4th–1/8th Ratti (15–30 mg) Swarnananoparticles revealed that it conjugatesBhasma8with antigen to influence the activation of T 2 Gunja (250 mg)9cell. Gold nano particles act as drug carrier 1 Gunja (125 mg)/As per age10an important demonstration of potential of 1 Harenu11multifunctional for drug delivery. Swarna 1/32 Ratti (3.9 mg)12bhasma should be generally administered 15.5–62.5 mg of Swarna Bhasma13.orally mixed with honey, ghee or milk.Ayurvedic property of gold-14AccordingMany pharmacoclinical studies shows thatto Ayurvedic literature it would possess thegoldfollowing properties –restorativeproperty19.Gold nano particlesRasa-kashaya, Tikta, madhura, katualso have adjuvant property. It act as anGuna-guru, snigdh, picchilaantigen carriers and activate phagocyticVeerya-sheeta (cold)activity of macrophages and influenced theVipaka-madhura (sweet)function of lymphocytes. Thus it isProperty-Swarna bhasma is sweet in taste,responsible for their immunomodulatingstrengthen the body, beneficial for heart andeffect. By conjugating with low and highgood for eyes, it also improve intellectualmolecular weight antigen, gold stimulatespower .due to it has the property to pacjfyrespiratoryall doshas it as a rasayan, and helpful inreticuloendothelial and also show antistresspunsamvan sanskar, it remove all toxicactivity20.Apharmaco-clinical study donesubstance from the body and good for skin.on rat at different point of time in restraintIt is also helpful to cure many diseases asinduced stress .Prior to this stress induction,anemia, tuberculosis, diarrhea, colitis, heartrats were treated with swarna bhasm. Thedisease, murcha etc.dose of swarna bhasm was 25 mg/kg orallyPharmacodynamic property of gold-for 10 days. HPLC technique was used toInayurvedicdetermine brain catecholamine, serotoninbhasmaand plasma corticosterone levels. The levelSwarna(gold)bhasma has been utilized forof brain catecholamines (norepinephrine,severalincludingepinephrine and dopamine), 5 HT andbronchial asthma, rheumatoid arthritis,plasma corticosterone was near to bediabetes mellitus and nervous systemnormal21.diseases15-18.SeveralToxicity Study done on ndoftheDivya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com160

A toxicity study was done on mice withused are more potent than the usual. Innanoparticle of 500nm for 15 days. Longayurved this day is best for collection ofterm survival and without toxicity wasdrugs.found in histological specimen of miceIMMUNOMODULATION EFFECT OFtissue (lungs, kidney, liver and spleen)22.SWARNA PRASHAN SANSKAR-Pharmacodynamic property of honey-A situation in which you are protectedHoneyandagainst disease is called body strength or wegluconic acid which are antibacterial incan say immuned. In ayurved it is coined byaction23.These two factors originated fromterm Vyadhikshamatva. Body strength ordissolution of sugar by glucose oxidase ofimmunity can be correlated with Ojas thathoney24-26. Honey also develops resistanceis bala (strength) of the body. Bala is ofagainst allergens remaining unaffected bythree type Sahajakalaja and Yuktikrita. Inthem. Due to its high sugar content it hasYuktikrita bala one can increase Ojas byhigh osmotic pressure unfavourable toYukti. Swarnaprashan is one of thebacterial growth and proliferation. Itsmethods which increase Sahaja bala or Ojasaromatic and phenolic compounds mayof the body without any adverse effect. Acontributestudy was done on timicrobialactivity27.Vacha combination in infants, the studyPharmacodynamic property of ghee–shows good response on immunologicalGhee pacifies Pitta and Vata, ghee issystem by a rise in the total proteins andbeneficial for rasa, sukra (semen) and Ojas,serumit pacifies burning sensation, it softensclinical study was done on gold nanobody, and improves voice and complexion.particles), which showed that gold nanoGhee has omega 6 and omega 3fatty acidparticles modulate the immunologicalwhich are good for neurological health andresponsebrain development28.inflammatory challenge. These resultsBenefits of Pushya Nakshtra-Due toindicatenourishing effect of Pushya Nakshtra allnanoparticles in diseases which involveayurvedic medicines are administered ininflammatory challenges31.Several studiesthis auspicious nakshtra29.The action ofon gold nano particles reveal that itdrug on this day is very fruitful. On this dayconjugates with antigen to influence thebody is in a better position to absorb theactivation of T cpharmcowithusageanofdrugs for its optimum benefits and the drugsDivya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com161

DISCUSSIONCONCLUSIONBrain development is continued up to 2Swarnprashanyears and at this stage by Swarnaprashanmultidimensional health by balancing theSansakar we can accelerate the growth ofphysicalbrain. According to Kashyapa Samhitafunctionsadministering Swarna to a child for oneSwarnaPrashana boosts the immunity asmonth, makes him Param Medhavi (superwell as intellectual power of a child. Goldintelligent) and by administering for up tohas anti-aging quality (Rasayana) andsix months, person becomes Shruta Dharaability to target drugs to the site (yogavahi).(can remember whatever she/ he hears)32.FurtherAs per literary review gold strengthens theundertaken to determine efficacy and safetybody, beneficial for heart (hridya), good forprofile of SwarnaPrashan in healthy andeyes (chakshusaya), improves intellectualdiseased ovidesmental(mansik)humanneedbody.tobepower, rejuvenative (rasayan), also helpfultocuremanydiseasesasanemia,tuberculosis, diarrhea, colitis, heart disease,etc33. Many pharmacoclinical studies showsthat gold nano particles helps in theactivation of T cell, act as a drug carrier, hasantioxidant and restorative property34. Goldhasadjuvantproperty,ithasimmunomodulating effect. It improves therecurrent attacks of common cold, fever andreversibleasthma.Inmalnourishedchildren, Suvarnaprashana Sanskar mayreduce the recurrent attacks of infectionsand help to improves digestive andmetabolic power. So from the abovediscussion we can conclude that gold(swarna) has many physical and mentalqualities that are beneficial for growingchild as well as adult.Divya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com162

di commentary, garbhini vyakaranmDr.Gorakhnath Chaturvedi, (2001) Charakshariram adhyaya , chapter 10 , verse 13-14,samhita, hindi commentary, Viman Sthan,313.Chapter1,RasViman,chaukhamba8. Kashinathvishvabharti , Varanasi, page no.680tarangani, 11th ed. New Delhi: Motilal2. Deepshikha (2014), critical analysis ofBanarasichildhood sanskaras (sacraments) in light of15th Taranga, 361–67.contemporary science, Int. J. Ayur. Pharma9. KulkarniResearch, 2(2): 95-100.Samuchaya, New Delhi: Mehar chand1. Pt.Kashi3. aSharma,RasaratnaVagbhata,Gorakhnath Chaturvedi, ( 2001), CharakVol. 1, 5/1, 11, 18, 13–6.Samhita, hindiShareera10. Dr.Bhaskar Govind Ghanekar, (2005),JatisutriyaSushruta Samhita, Varanasi Chaukhambashareeradhyaya, chaukhamba vishvabharti,Orientalia, Dalhana, Commentator, ShariraVaranasi, page no.950.Sthana 10/13-15, 68-70, reprint ed., 388–4. K.B.Jyothy, Srihari Sherhagiri, Kalpana95.S.Patel and S.Rajagopala (2014), A critical11. Hari Shastri Paradka, Astanga Hridya,appraisal on Swarnaprashana in children,(2002),AYU, oct-dec, 35 (4), 361-365.Adhyaya. 1/9, 47-48, 9th ed. Varanasi5. Dr. P.V.Tiwari (1996), 1st Ed., KashyapaChaukhambha Orientalia, 778–781.Samhita,and12. . Brhma Shankar Tripathi, (2009),commentary, sutra sthana, chapter-18 ,Bhaishajya Ratnavali, Balarogachikitsa,verses-26-28, chaukhamba vishva bharti,71/5-6, 19th ed., Varanasi: ChaukhambaVaranasi, 7.Prakashan, UttaraSthana,(2000),second13. AnonymousSamgraha,English18:20. 2nd ed. Delhi, The Controller oftranslation, Uttar sthan, chapter -1 ,Publications, Govt of India; The AyurvedicBalopacaraniya, verses-10, second edition ,Formulary of India; p. 247.2.14. Shri Sadananda Sharma, (1994), Ras7. Dr.Bhaskar Govind Ghanekar, (2013),tarangani, 11thedition, motilal banarasidasSushruta Samhita, Sharira Sthana withPrakashan,6. iyaSuvarnaPart-I,Sectvigyaniya,Panchdashtarang, 374-377.Divya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com163

15. Kulkarni DA., (1998), Ras RatnaSystem of Medicine, Basic and clinicalSamucchayaPharmacology and Toxicology,96:469–74.VijnanabodhiniCommentary. New Delhi, India: Mehar22. Christianchand Lachhman das Publications.RachelCouderc,16. Acharya Shri Radha Krishna Parashar,Villiers,and(1994), Sarangadhara-Samhita, publishedAnalysis of the Toxicity of Gold nanoby Baidhyanath Ayurved Bhawan, 382.particles on the Immune system , effect on17. ritic tions,Freitas,(2010),J. NanopartResearch, Jan , 12 (1) 55-60.for Ayurvedic Formulations. Vol. 15, New23. Ellen cristina Gaetti-Jardim, AntonioDelhi India, Central Council for ResearchCarlosinFaverani, and Elerson Jardim , rez(CCRIMH).Antimicrobial resistance of aerobes and18. Bajaj S, Vohora SB., (2000), Anti-facultative anaerobes isolated from the oralCataleptic,cavity, Journal of applied Oral Science,Anti-AnxietyandAnti-Depressant Activity of Gold PreparationsDec, 18 (6) 551-9.Used in Indian Systems of Medicine, Ind. J24. Molan P, (1992), The antibacterialPharmacol. 32:339–46.activity of honey. 2. Variation in the19. ctsofpotency of the antibacterial activity,International Bee Research Association, 73Calcined Gold Preparations Used in Indian(2), 59-76.Systems of Medicine against Global and25. Al- Naama RT (2009) Evaluation of in-Focal Models of Ischaemia, Pub Med, may,vitro inhibitory effect of honey on some90 (5), 254-9.microbial isolate, Iraqi J Med Sci, 1: 64-67.20. Lev A. Dykman, Nikalai G.Khlebtsov,26. Ruiz–Argueso T, Rodriguez-Navarro(2016), Immunological properties of goldA (1973) Gluconic acid-producing bacteriananoparticles, The Royal Society offrom honey bees and ripening Honey, J GenChemical Science, 1719-1735.Microbiol 76: 211-216.21. Shah ZA, Gilani RA, Sharma P,27. Weston RJ, Mitchell KR, Allen KLVohora SB.(2005), Attenuation of Stress-(1999), Antibacterial phenolic componentsElicited Brain Catecholamines, Serotoninof New Zealand Manuka honey, J Foodand Plasma Corticosterone Levels byChem, 64: 295-301.Calcined Gold Preparations Used in IndianDivya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com164

28. S.C.Dyall, A.T.Michael-Titus, (2008),34. ShahNeurological benefits of omega-3 fattyAntioxidant/Restorativeacids, Neuromolecular Medicine, VolumeCalcined Gold Preparations Used in Indian10, Issue 4, 219-235.Systems of Medicine against Global and29. Amarasimha,(2008)Amarakosa,Prathama Kanda, Digvarga, Varanasi,ZA,VohoraSB,(2002),EffectsofFocal Models of Ischaemia, Pub Med, may,90 (5), 254-9.Chaukhambha Sanskrit Sansthan, p. 48.30. ctof Madhu-Ghrita and Swarna-VachaMadhu-Ghritaonneonates, Jamnagar. India: Institute for PostGraduateTeachingandResearchinAyurveda, Gujarat Ayurved University;P.G. Dissertation work.31. DanielF.Moyano,YuanchangLiu, Furkan Ayaz, Singyuk Hou, PremsakPuangploy, Bradley Duncan, Barbara A.Osborne, and Vincent M. Rotello , (2016),Immunomodulatory effects of coated goldnanoparticlesinLPS-stimulatedinvitro and in vivo murine model systems,Pub Med, Chem, Aug 11,320-327.32. Dr.P.V.Tiwari(1996),1stEd.,Kashyapa Samhita, English translation andcommentary, Sutra Sthana, Chapter-18,verses-26-28, by chaukhamba vishvabharti,Varanasi, page no -7.33. Shri sadananda Sharma, (1994), Rastaranganiby,11thedition,MotilalBanarasidas Prakashan, Suvarna vigyaniya,Panchdash tarang page no. 374-377.Divya et al.Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2[e ISSN 2350-0204]2019 Greentree Group Publishers IJAPCwww.ijapc.com165

Int J Ayu Pharm Chem 2019 Vol. 10 Issue 2 www.ijapc.com 157 [e ISSN 2350-0204] Int J Ayu Pharm Chem REVIEW ARTICLE www.ijapc.com e-ISSN 2350-0204 ABSTRACT Swarna Prashan Sanskar mentioned under shodash sanskar is an ancient ritual. SwarnaPrashana means to administer Swarna (gold) in liquid form along with honey, ghee and some herbal .

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